Randomised controlled trial of long-term maintenance corticosteroid therapy in patients with autoimmune pancreatitis.

abstract：:Forty patients with endoscopically proven persistent duodenal ulcer who had been treated for six weeks with cimetidine (1 g/day) were randomly allocated to receive a further six weeks' treatment with cimetidine (1 g/day) or ranitidine (300 mg/day). Ulcers healed in 12 of 19 patients given cimetidine (63%) and in 13 of...

journal_title：Gut

authors： Quatrini M,Basilisco G,Bianchi PA

更新日期：1984-10-01 00:00:00

abstract：:The prevalence of methane production in an adult population of 256 subjects was 41%, but it was significantly higher in females (49%), than males (33%). When the population was subdivided into ethnic groups. Caucasians (48%) and Black (45%) had significantly more methane producers than Orientals (24%) and Indians (32%...

journal_title：Gut

authors： Pitt P,de Bruijn KM,Beeching MF,Goldberg E,Blendis LM

更新日期：1980-11-01 00:00:00

abstract：:Colonic biopsy specimens were obtained from patients undergoing surgery for carcinoma of the rectum. Colonic resistance arteries (internal diameter 178-345 microns) were dissected out under the microscope and mounted in a microvascular myograph capable of measuring isometric tension development. Experiments were desig...

journal_title：Gut

authors： Mortensen FV,Nielsen H,Mulvany MJ,Hessov I

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:Adherent-invasive Escherichia coli (AIEC) are a leading candidate bacterial trigger for Crohn's disease (CD). The AIEC pathovar is defined by in vitro cell-line assays examining specific bacteria/cell interactions. No molecular marker exists for their identification. Our aim was to identify a molecular proper...

journal_title：Gut

authors： O'Brien CL,Bringer MA,Holt KE,Gordon DM,Dubois AL,Barnich N,Darfeuille-Michaud A,Pavli P

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Bleeding after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) is a frequent adverse event after ESD. We aimed to develop and externally validate a clinically useful prediction model (BEST-J score: Bleeding after ESD Trend from Japan) for bleeding after ESD for EGC. DESIGN:This retrospe...

journal_title：Gut

authors： Hatta W,Tsuji Y,Yoshio T,Kakushima N,Hoteya S,Doyama H,Nagami Y,Hikichi T,Kobayashi M,Morita Y,Sumiyoshi T,Iguchi M,Tomida H,Inoue T,Koike T,Mikami T,Hasatani K,Nishikawa J,Matsumura T,Nebiki H,Nakamatsu D,Ohnit

更新日期：2020-06-04 00:00:00

abstract：AIM:This prospective study aimed to compare the accuracy of echo enhanced ultrasound with spiral computed tomography (CT) in assessing acute pancreatitis and to explore the correlation between ultrasound findings and clinical outcome. METHODS:Thirty one patients (24 men and 7 women, median age 39 years, range 19-67 ye...

journal_title：Gut

authors： Rickes S,Uhle C,Kahl S,Kolfenbach S,Monkemuller K,Effenberger O,Malfertheiner P

更新日期：2006-01-01 00:00:00

abstract：:We report two patients with periampullary cysts associated with recurrent attacks of acute pancreatitis. In both patients the diagnosis was made preoperatively by upper gastrointestinal endoscopy and ERCP, which was also useful in determining the relationship of the cysts to the biliary and pancreatic ductal systems. ...

journal_title：Gut

authors： Kalvaria I,Bornman PC,Girdwood AH,Marks IN

更新日期：1987-03-01 00:00:00

abstract：:Thirty male patients (27 homosexual) with biopsy proven chronic active hepatitis B were randomised to receive lymphoblastoid interferon (Wellferon) or no treatment. All patients were HBeAg positive and had continuing viral replication. Patients receiving treatment were given a single daily intramuscular injection of i...

journal_title：Gut

authors： Anderson MG,Harrison TJ,Alexander G,Zuckerman AJ,Murray-Lyon IM

更新日期：1987-05-01 00:00:00

abstract：:Human intrahepatic biliary epithelial cells were isolated from the livers of patients with primary biliary cirrhosis and from normal livers and established in primary culture. The in vitro expression of intercellular adhesion molecule-1, HLA class I, and HLA class II on biliary epithelial cells was studied in response...

journal_title：Gut

authors： Ayres RC,Neuberger JM,Shaw J,Joplin R,Adams DH

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Recently, non-invasive techniques such as 3 dimensional ultrasonography (3DUS) have been developed to assess gastric wall characteristics and to investigate their relationship with upper gastrointestinal sensations. To date, no head-to-head comparison has been carried out between the barostat and the 3DUS te...

journal_title：Gut

authors： Mundt MW,Samsom M

更新日期：2006-12-01 00:00:00

abstract：:Previous reports have shown that both Crohn's disease and ulcerative colitis affect people in white collar occupations associated with higher income and higher social class more frequently than other groups in the population. This study sought to carry these analyses one step further and investigate the distribution o...

journal_title：Gut

authors： Sonnenberg A

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVES:Lipid mediators in the GI tract regulate satiation and satiety. Bile acids (BAs) regulate the absorption and metabolism of dietary lipid in the intestine, but their effects on lipid-regulated satiation and satiety are completely unknown. Investigating this is challenging because introducing excessive BAs or ...

journal_title：Gut

authors： Higuchi S,Ahmad TR,Argueta DA,Perez PA,Zhao C,Schwartz GJ,DiPatrizio NV,Haeusler RA

更新日期：2020-09-01 00:00:00

abstract：:Visceral hypersensitivity has been recognised as a characteristic of patients with irritable bowel syndrome (IBS). It may be involved in the pathogenesis of abdominal pain/discomfort, and seems to result from the sensitisation of nerve afferent pathways originating from the gastrointestinal tract. From a clinical poin...

journal_title：Gut

authors： Delvaux M

更新日期：2002-07-01 00:00:00

abstract：:The isoenzyme pattern of lactic dehydrogenase was measured in rectal biopsies from six patients with ulcerative colitis in whom precancerous histological changes had been independently recognized. There was a highly significant increase in the ratio of isoenzymes IV + V to I + II. This suggests that lactic dehydrogena...

journal_title：Gut

authors： Lewis B,Morson BC,February AW,Jones JH,Misiewicz JJ

更新日期：1971-01-01 00:00:00

abstract：:This study was undertaken to determine the effect of cyclophosphamide, methotrexate, hydrocortisone, and cyclosporin A on a model of granulomatous infiltration in the terminal ileum and draining lymph nodes of the guinea pig. Treatment groups of six animals were used and compared to untreated groups of 12. Epithelioid...

journal_title：Gut

authors： Mitchell IC,Turk JL

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma cells express high levels of the antiapoptotic proteins Bcl-X(L) and Mcl-1 and are markedly chemo- and radioresistant. Mitochondria have emerged as central players in apoptosis. Antiapoptotic members of the Bcl-2 protein family localise to the outer mitochondrial membrane and regulate mito...

journal_title：Gut

authors： Okaro AC,Fennell DA,Corbo M,Davidson BR,Cotter FE

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Interstitial cells of Cajal (ICC) are pacemakers and mediators of motor neurotransmission in gastrointestinal smooth muscles. ICC require cellular signalling via Kit, a receptor tyrosine kinase, for development and maintenance of phenotype. Much of the evidence demonstrating the functions of ICC com...

journal_title：Gut

authors： Takayama I,Daigo Y,Ward SM,Sanders KM,Walker RL,Horowitz B,Yamanaka T,Fujino MA

更新日期：2002-06-01 00:00:00

abstract：:Daytime intragastric pH, fasting and meal stimulated serum gastrin and nocturnal acid output were studied in eight male duodenal ulcer patients before, during and two days after completing nizatidine 300 mg nocte (20:00 h) for four weeks. Median nocturnal acid output (mmol/10 h) decreased during treatment to 11.6 (ran...

journal_title：Gut

authors： Fullarton GM,McLauchlan G,Macdonald A,Crean GP,McColl KE

更新日期：1989-04-01 00:00:00

abstract：:A manometric method was developed to study the motor activity in the unprepared human colon, and the results in eight healthy subjects were compared with those obtained in the same subjects after bowel cleansing with a non-absorbable solution containing polyethylene glycol 4000 (PEG). A tube assembly (4.5 m long, 12 l...

journal_title：Gut

authors： Lémann M,Flourié B,Picon L,Coffin B,Jian R,Rambaud JC

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:The transcriptional profile of gastric epithelial cell lines cocultured with Helicobacter pylori and the global gene expression of whole gastric mucosa has been described previously. We aimed to overcome limitations of previous studies by determining the effects of H pylori eradication on the transcriptome of...

journal_title：Gut

authors： Resnick MB,Sabo E,Meitner PA,Kim SS,Cho Y,Kim HK,Tavares R,Moss SF

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Altered matrix degradation contributes to fibrosis in some liver diseases but the role of matrix degradation in fibrogenesis associated with genetic haemochromatosis has not previously been addressed. AIMS:To measure serum concentrations of tissue inhibitor of metalloproteinase 1 (TIMP-1) and matrix metallo...

journal_title：Gut

authors： George DK,Ramm GA,Powell LW,Fletcher LM,Walker NI,Cowley LL,Crawford DH

更新日期：1998-05-01 00:00:00

abstract：:In man, the main pancreatic duct is normally derived from ventral and dorsal embryological buds of the pancreas. In a minority of people, failure of fusion of the two buds results in separate drainage of the dorsal and ventral pancreas, so that the accessory duct provides the main drainage for the gland. Patients with...

journal_title：Gut

authors： Mitchell CJ,Lintott DJ,Ruddell WS,Losowsky MS,Axon AT

更新日期：1979-12-01 00:00:00

abstract：:This paper reports the association between severe, prolonged, watery diarrhoea and islet cell tumours of the pancreas. There appear to be significant differences between patients with these symptoms and those with the classical Zollinger-Ellison syndrome. ...

journal_title：Gut

authors： TELLING M,SMIDDY FG

更新日期：1961-03-01 00:00:00

abstract：:In order to investigate further the reported beneficial effect of deglycyrrhizinated liquorice in gastric ulcer, a trial with a double-blind, cross-over design was performed. The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo du...

journal_title：Gut

authors： Engqvist A,von Feilitzen F,Pyk E,Reichard H

更新日期：1973-09-01 00:00:00

abstract：BACKGROUND:Small bowel transplantation remains a difficult therapeutic option endangered by a high rate of rejection and infectious complications. To improve these clinical results, it is mandatory to set up animal models to test alternative immunosuppressive regimens which may lead to immunotolerance. AIMS:To determi...

journal_title：Gut

authors： Sarnacki S,Auber F,Crétolle C,Camby C,Cavazzana-Calvo M,Müller W,Wagner N,Brousse N,Révillon Y,Fischer A,Cerf-Bensussan N

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:HCV is a major cause of chronic liver disease worldwide, but the role of neutralising antibodies (nAbs) in its natural history remains poorly defined. We analysed the in vivo role of hypervariable region 1 (HVR1) for HCV virion properties, including nAb susceptibility. DESIGN:Analysis of HCV from human liver...

journal_title：Gut

authors： Prentoe J,Verhoye L,Velázquez Moctezuma R,Buysschaert C,Farhoudi A,Wang R,Alter H,Meuleman P,Bukh J

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Dietary fibre has beneficial effects on energy metabolism, and the majority of studies have focused on short-chain fatty acids produced by gut microbiota. Ginseng has been reported to aid in body weight management, however, its mechanism of action is not yet clear. In this study, we focused on the potential m...

journal_title：Gut

authors： Quan LH,Zhang C,Dong M,Jiang J,Xu H,Yan C,Liu X,Zhou H,Zhang H,Chen L,Zhong FL,Luo ZB,Lam SM,Shui G,Li D,Jin W

更新日期：2020-07-01 00:00:00

abstract：:This case report describes the histological and macroscopic changes seen within a few months in the gastric mucosa of a 28 year old woman patient with upper abdominal symptoms. With hindsight these changes were the first signs of Sjögren's syndrome. ...

journal_title：Gut

authors： van Leeuwen ML,Tjiong HL,van Blankenstein M,Mulder AH,Bakker CM

更新日期：1993-08-01 00:00:00

abstract：:Bacterial contamination of gastrointestinal fibre-endoscopes is a potential source of clinically significant infection. Aqueous 2% alkaline glutaraldehyde adequately disinfects fibre-endoscopes but may cause serious sensitivity reactions among endoscopy staff. A new 'closed-system' disinfecting apparatus is described ...

journal_title：Gut

authors： O'Connor HJ,Rothwell J,Maxwell S,Lincoln C,Axon AT

更新日期：1982-08-01 00:00:00

abstract：:125I-labelled human trypsin metabolism has been investigated in man. Three subjects received 125I-trypsin and 131I-albumin intravenously. Against a background secretin infusion (1 U/kg/h), trypsin decayed biexponentially from the serum with half-lives of 17.5, 21, and 24 minutes for the rapid disappearance phase and 5...

journal_title：Gut

authors： Lake-Bakaar G,Rubio CE,McKavanagh S,Potter BJ,Summerfield JA

更新日期：1980-07-01 00:00:00