High plasma coenzyme Q10 concentration is correlated with good left ventricular performance after primary angioplasty in patients with acute myocardial infarction.

Abstract:

:Exogenous administration of coenzyme Q10 (CoQ10) has been shown in experimental models to have a protective effect against ischemia-reperfusion injury. However, it is unclear whether follow-up plasma CoQ10 concentration is prognostic of left ventricular (LV) performance after primary balloon angioplasty in patients with acute ST segment elevation myocardial infarction (STEMI).We prospectively recruited 55 patients with STEMI who were treated with primary coronary balloon angioplasty. Plasma CoQ10 concentrations were measured before primary angioplasty (baseline) and 3 days, 7 days, and 1 month after STEMI using high-performance liquid chromatography. Echocardiography was performed at baseline and at 6-month follow-up. The control group comprised 54 healthy age- and sex-matched volunteers.Serial circulating CoQ10 concentrations significantly decreased with time in the STEMI group. The LV ejection fraction at 6-month follow-up positively correlated with the 1-month plasma CoQ10 tertile. Higher plasma CoQ10 concentrations at 1 month were associated with favorable LV remodeling and systolic function 6 months after STEMI. Multiple linear regression analysis showed that changes in CoQ10 concentrations at 1-month follow-up were predictive of LV systolic function 6 months after STEMI. Changes in CoQ10 concentrations correlated negatively with baseline oxidized low-density lipoprotein and fibrinogen concentrations and correlated positively with leukocyte mitochondrial copy number at baseline.Patients with STEMI who had higher plasma CoQ10 concentrations 1 month after primary angioplasty had better LV performance at 6-month follow-up. In addition, higher plasma CoQ10 concentration was associated with lower grade inflammatory and oxidative stress status. Therefore, plasma CoQ10 concentration may serve as a novel prognostic biomarker of LV systolic function after revascularization therapy for acute myocardial infarction.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Huang CH,Kuo CL,Huang CS,Tseng WM,Lian IB,Chang CC,Liu CS

doi

10.1097/MD.0000000000004501

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

e4501

issue

31

eissn

0025-7974

issn

1536-5964

pii

00005792-201608020-00086

journal_volume

95

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Removal of the root canal smear layer using Carisolv III and sodium hypochlorite.

    abstract::The present study investigated the effectiveness of a Carisolv III + 0.5% sodium hypochlorite (NaOCl)-based root canal irrigant for smear layer removal.Forty maxillary incisors were randomly divided into 4 groups (n = 10 per group). The canals in group A (experimental) were prepared with 0.5% NaOCl, and Carisolv III a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020372

    authors: Wu D,Ma YZ,Jia J,Xin BC,Wang DS,Sun DG,Wang LX

    更新日期:2020-05-29 00:00:00

  • 11C-acetate and 18F-fluorodeoxyglucose positron emission tomography/computed tomography dual imaging for the prediction of response and prognosis after transarterial chemoembolization.

    abstract::The aim of the present study was to evaluate the clinical significance of dual radiotracer studies, C-acetate and F-fluoro-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT), for the prediction of response and recurrence after transarterial chemoembolization (TACE).This study retrospectively inc...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012311

    authors: Park S,Kim TS,Kang SH,Kim HB,Park JW,Kim SK

    更新日期:2018-09-01 00:00:00

  • Eosinophilic esophagitis in an octogenarian: A case report and review of the literature.

    abstract:INTRODUCTION:Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated disease characterized clinically by symptoms related to esophageal dysfunction and histologically by a marked eosinophilic infiltrate in the esophageal mucosa. What was once considered a rare disease has nowadays become one of the most fr...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000005169

    authors: Trifan A,Stoica O,Chihaia CA,Danciu M,Stanciu C,Singeap AM

    更新日期:2016-10-01 00:00:00

  • Short- and Long-Term Patient Outcomes From Combined Coronary Endarterectomy and Coronary Artery Bypass Grafting: A Meta-Analysis of 63,730 Patients (PRISMA).

    abstract::This meta-analysis aimed to compare the short- and long-term outcomes in patients undergoing combined coronary endarterectomy and coronary artery bypass grafting (CE + CABG) versus isolated CABG, and particularly to examine subgroup patients with high-risk profile and patients with diffuse disease in the left anterior...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000001781

    authors: Wang J,Gu C,Yu W,Gao M,Yu Y

    更新日期:2015-10-01 00:00:00

  • Prognostic role of platelet-lymphocyte ratio in colorectal cancer: A systematic review and meta-analysis.

    abstract::Many studies have been reported that platelet-lymphocyte ratio (PLR) may be associated with the prognosis of colorectal cancer (CRC), but the results are inconsistent. Current opinion on the prognostic role of the PLR in CRC is inconsistent and inconclusive. Therefore, we conduct a meta-analysis that combines these st...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003837

    authors: Tan D,Fu Y,Su Q,Wang H

    更新日期:2016-06-01 00:00:00

  • Natural history of adults with congenitally malformed aortic valves (unicuspid or bicuspid).

    abstract::Appreciation of the frequency of the congenitally malformed aortic valve has come about during the last 50 years, a period during which aortic valve replacement became a predictably successful operation. Study of patients at necropsy with either a congenitally unicuspid (1 true commissure) or bicuspid (2 true commissu...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0b013e3182764b84

    authors: Roberts WC,Vowels TJ,Ko JM

    更新日期:2012-11-01 00:00:00

  • Influence of surgical margins on overall survival after resection of intrahepatic cholangiocarcinoma: A meta-analysis.

    abstract:BACKGROUND:Surgical resection is shown to present the best chance of cure in the treatment of intrahepatic cholangiocarcinoma (ICC). However, the appropriate length of the negative margin remains unclear. The aim of the present meta-analysis was to investigate whether a clear margin of 10 mm or more (≥10 mm) conferred ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000004621

    authors: Tang H,Lu W,Li B,Meng X,Dong J

    更新日期:2016-08-01 00:00:00

  • Aggravation of an injured dentato-rubro-thalamic tract in a patient with mild traumatic brain injury: A case report.

    abstract:RATIONALE:We report on a patient with mild traumatic brain injury (TBI) by follow-up diffusion tensor tractography (DTT), and observed for approximately nine monthsby serial diffusion tensor tractography (DTT). PATIENT CONCERNS:A 66-year-old male patient was injured in a car crash. Approximately four weeks after the c...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008253

    authors: Jang SH,Kwon HG

    更新日期:2017-10-01 00:00:00

  • Impact of statin use on cancer-specific mortality and recurrence: A meta-analysis of 60 observational studies.

    abstract::This meta-analysis mainly summarized the studies reporting an association between statin use and cancer-specific mortality and recurrence or progression of cancer patients.We systematically searched for studies about the statin used in cancer patients in electronic databases, including PubMed, Web of Science, Cochrane...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000019596

    authors: Yang J,Li C,Shen Y,Zhou H,Shao Y,Zhu W,Chen Y

    更新日期:2020-04-01 00:00:00

  • The association between normal-range admission potassium levels in Israeli patients with acute coronary syndrome and early and late outcomes.

    abstract::Abnormal serum potassium levels are associated with an increased risk of ventricular arrhythmias and mortality in patients with acute myocardial infarction (AMI). The aim of the present study was to evaluate whether different levels of serum potassium, within the normal range, are associated with worse outcomes. The p...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000003778

    authors: Shlomai G,Berkovitch A,Pinchevski-Kadir S,Bornstein G,Leibowitz A,Goldenberg I,Grossman E

    更新日期:2016-06-01 00:00:00

  • Treatment of herpes labialis by photodynamic therapy: Study protocol clinical trial (SPIRIT compliant).

    abstract:BACKGROUND:Lesions of herpes labialis are caused by the herpes simplex virus type 1 and cause pain and aesthetic compromise. It is characterized by the formation of small vesicles that coalesce and rupture forming extremely painful ulcers, that evolve to crusts, dry desquamations until their complete remission. Current...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000019500

    authors: La Selva A,Negreiros RM,Bezerra DT,Rosa EP,Pavesi VCS,Navarro RS,Bello-Silva MS,Ramalho KM,Aranha ACC,Braz-Silva PH,Fernandes KPS,Bussadori SK,Horliana ACRT

    更新日期:2020-03-01 00:00:00

  • Prognostic significance of KIF2A and KIF20A expression in human cancer: A systematic review and meta-analysis.

    abstract:BACKGROUND:The kinesin family (KIF) is reported to be aberrantly expressed and significantly correlated with survival outcomes in patients with various cancers. This meta-analysis was carried out to quantitatively evaluate the prognostic values of partial KIF members in cancer patients. METHODS:Two well-known KIF memb...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000018040

    authors: Li X,Shu K,Wang Z,Ding D

    更新日期:2019-11-01 00:00:00

  • Use of methotrexate in the management of recurrent Tolosa-Hunt syndrome: Two case reports.

    abstract:RATIONALE:Tolosa-Hunt syndrome (THS) is rare condition characterized by painful ophthalmoplegia that usually responds well to corticosteroid. About a half of THS patients experience recurrence within intervals of months to years from initial presentation. Recurrence is more common in younger patients, and can be ipsila...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019882

    authors: Kwon HS,Kim TY,Kim JH,Bae JH,Koh SH,Choi H,Lee KY,Lee YJ,Kim YS,Kim HY

    更新日期:2020-04-01 00:00:00

  • Prognostic value of pretreatment neutrophil-to-lymphocyte ratio in patients with soft tissue sarcoma: A meta-analysis.

    abstract:BACKGROUND:The neutrophil-to-lymphocyte ratio (NLR) has been reported to possess significant prognostic value in multiple types of cancer. We conducted a meta-analysis to evaluate the prognostic value of pretreatment NLR in soft tissue sarcoma (STS). METHODS:A systematic literature search through April 2018 was conduc...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000012176

    authors: Liu G,Ke LC,Sun SR

    更新日期:2018-09-01 00:00:00

  • Doege-Potter syndrome: A review of the literature including a new case report.

    abstract:RATIONALE:We reviewed 76 published cases of Doege-Potter syndrome, and non-islet cell tumor hypoglycemia (NICTH) secondary to a solitary fibrous tumor (SFT) between 1989 and 2016, to study disease pathogenesis, diagnosis, and treatment of this rare paraneoplastic disease. Further, we report 1 new case of a patient pres...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000007417

    authors: Han G,Zhang Z,Shen X,Wang K,Zhao Y,He J,Gao Y,Shan X,Xin G,Li C,Liu X

    更新日期:2017-07-01 00:00:00

  • No association between abortion and risk of breast cancer among nulliparous women: Evidence from a meta-analysis.

    abstract:BACKGROUND:Various epidemiological studies have demonstrated the association between abortion and risk of breast cancer among nulliparous women; however, results remain inconclusive. This meta-analysis assessed the association based on previous studies. METHODS:PubMed, EMBase, China National Knowledge Infrastructure, ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000020251

    authors: Tong H,Wu Y,Yan Y,Dong Y,Guan X,Liu Y,Lu Z

    更新日期:2020-05-01 00:00:00

  • The effectiveness and safety of extracorporeal shock wave lithotripsy for the management of kidney stones: A protocol of systematic review and meta-analysis.

    abstract:BACKGROUND:Extracorporeal shockwave lithotripsy (ESWL) has gained worldwide popularity as one of the most commonly used minimally invasive management of urinary tract stones. The objective of this study was to evaluate the efficacy and safety of ESWL for patients with kidney stones (KS). MATERIALS AND METHODS:This pro...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021910

    authors: Cao L,Wang YQ,Yu T,Sun Y,He J,Zhong Y,Li X,Sun X

    更新日期:2020-09-18 00:00:00

  • Clinical characteristics of dysphagic stroke patients with salivary aspiration: A STROBE-compliant retrospective study.

    abstract::The aim of this study was to evaluate the correlation between radionuclide salivagram findings and clinical characteristics in stroke patient with swallowing difficulty.In this study, dysphagic stroke patients who had undergone both a radionuclide salivagram and videofluoroscopic swallowing study (VFSS) were included ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014977

    authors: Yu KJ,Park D

    更新日期:2019-03-01 00:00:00

  • Prognostic Effects of Adjuvant Chemotherapy-Induced Amenorrhea and Subsequent Resumption of Menstruation for Premenopausal Breast Cancer Patients.

    abstract::Chemotherapy-induced amenorrhea (CIA) is a side effect that occurs in patients with breast cancer (BC) as a result of chemotherapy. These patients require special treatments to avoid infertility and menopause. However, the factors controlling CIA, resumption of menstruation (RM), and persistence of menstruation after ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003301

    authors: Jeon SJ,Lee JI,Jeon MJ,Lee M

    更新日期:2016-04-01 00:00:00

  • Do routine blood test results help in the diagnosis of spine tumors? A retrospective study of the significance of pretreatment neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios from 503 spine tumor patients.

    abstract::The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are not fully evaluated for the diagnosis of musculoskeletal tumors, especially spine tumors. The objective of our study was to assess the feasibility of NLR and PLR as indicators for pretreatment diagnosis of spine tumors.Patients who...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014902

    authors: Li Y,Wang B,Zhou S,Jiang L,Yang S,Liu X,Wei F,Zhang H,Wang Y,Liu Z

    更新日期:2019-04-01 00:00:00

  • Association between the use of antibiotics and efficacy of gemcitabine plus nab-paclitaxel in advanced pancreatic cancer.

    abstract::It is unclear whether the use of antibiotics is related to the efficacy of gemcitabine plus nab-paclitaxel (GnP). Therefore, we investigated the association between the use of antibiotics and efficacy of GnP.We conducted a retrospective single center study from January 2014 to December 2018 in Hokkaido University Hosp...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022250

    authors: Nakano S,Komatsu Y,Kawamoto Y,Saito R,Ito K,Nakatsumi H,Yuki S,Sakamoto N

    更新日期:2020-09-25 00:00:00

  • Correlation analysis and clinical significance of CA125, HE4, DDI, and FDP in type II epithelial ovarian cancer.

    abstract::Ovarian cancer is one of the common female malignant tumors. The early diagnosis and treatment of ovarian cancer has been a research hotspot. Therefore, we aimed to investigate the correlations between the levels of carbohydrate antigen 125 (CA125), human epididymis protein 4 (HE4), D-dimer (DDI), and fibrinogen degra...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023329

    authors: Qiao L,Chen X,Xi X,Chen X,Zhang P,Dong H,Wu X,Chen X

    更新日期:2020-12-04 00:00:00

  • Tension band wiring for proximal femoral varus osteotomy fixation in children.

    abstract::For proximal varus osteotomy of the femur in children, a stable fixation, is a concern regarding the safety and the protection of the surgery. The methods of fixation are mostly represented by plating systems; however, the tension band wiring is a simple and eligible option for fixation of proximal femur osteotomy. Th...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000061

    authors: Maranho DA,Pagnano RG,Volpon JB

    更新日期:2014-08-01 00:00:00

  • Orthostatic Hypotension and Mortality in Elderly Frail Patients: A Retrospective Cross-Sectional Study.

    abstract::Orthostatic hypotension (OH) is a common problem in the elderly age group, and some studies have reported an association between OH and increased mortality. We evaluated possible associations between OH and mortality in a retrospective study of frail elderly patients who came for a comprehensive geriatric assessment. ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000977

    authors: Freud T,Punchik B,Press Y

    更新日期:2015-06-01 00:00:00

  • Successful treatment of disseminated intravascular coagulation by recombinant human soluble thrombomodulin in patients with acute myeloid leukemia.

    abstract::Disseminated intravascular coagulation (DIC) is a life-threatening condition that frequently occurs in patients with hematologic malignancies. Currently, recombinant human soluble thrombomodulin (rTM) is a therapeutic DIC drug that is manufactured and sold in Japan only. We evaluated the efficacy of rTM compared to th...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012981

    authors: Ookura M,Hosono N,Tasaki T,Oiwa K,Fujita K,Ito K,Lee S,Matsuda Y,Morita M,Tai K,Negoro E,Kishi S,Iwasaki H,Ueda T,Yamauchi T

    更新日期:2018-11-01 00:00:00

  • A clinical prediction rule for acute bilirubin encephalopathy in neonates with extreme hyperbilirubinemia: A retrospective cohort study.

    abstract::To establish a clinical prediction rule for acute bilirubin encephalopathy (ABE) in term/near-term neonates with extreme hyperbilirubinemia.A retrospective cohort study was conducted between January 2015 and December 2018. Six hundred seventy-three out of 26,369 consecutive neonates with extreme hyperbilirubinemia wer...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019364

    authors: Zhang F,Chen L,Shang S,Jiang K

    更新日期:2020-02-01 00:00:00

  • The value of the air bronchogram sign on CT image in the identification of different solitary pulmonary consolidation lesions.

    abstract::The aim of the present study is to investigate the value of air bronchogram sign on computed tomography (CT) image in the differential diagnosis of solitary pulmonary consolidation lesions (SPLs).A total of 105 patients (including 39 cases of lung cancer, 43 cases of tuberculosis, and 23 cases of pneumonia) with SPLs ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011985

    authors: Qu H,Zhang W,Yang J,Jia S,Wang G

    更新日期:2018-08-01 00:00:00

  • Auricular acupressure for overweight and obese individuals: A systematic review and meta-analysis.

    abstract:BACKGROUND:Auricular acupressure has been used for treating obesity, but inconsistent outcomes have been reported. Moreover, systematic reviews and meta-analyses have seldom addressed the effects of auricular acupressure and duration of treatment in overweight/obese individuals. This study reviewed research articles on...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000016144

    authors: Huang CF,Guo SE,Chou FH

    更新日期:2019-06-01 00:00:00

  • Effect of morphine added to multimodal cocktail on infiltration analgesia in total knee arthroplasty: A meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:The local injection of multimodal cocktail is currently commonly used in the treatment of postoperative pain after total knee arthroplasty (TKA). It is still inconclusive whether the morphine added to the intraoperative injection mixture could make some difference. This meta-analysis aimed to evaluate the ef...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000017503

    authors: Zhang Y,Mi F,Zhao H,Xie D,Shi X

    更新日期:2019-10-01 00:00:00

  • Efficacy and safety of Xiyanping for COVID-2019: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) is a global pandemic caused by the severe acute respiratory syndrome coronavirus-2.COVID-19 is highly pathogenic and infectious. COVID-19 epidemic is still spreading all over the world, and there is no sign of stopping at present. There is no specific cure for this disease...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000022962

    authors: Zhou H,Chen D,Zhang Y,Zhu Q,Yang Y,Liu Y,Gong G,Xie C

    更新日期:2020-11-13 00:00:00