Abstract:
AIM:To assess the diagnostic value of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in lung cancer (LC). We compared the ratios between healthy participants and all LC patients, as well patients with different pathohistological LC subtypes. METHODS:We retrieved the data on neutrophil, lymphocyte, and platelet levels in 449 patients with different pathohistological LC subtypes (non-small cell LC, small-cell LC, atypical or metastatic LC, neuroendocrine, and sarcomatoid carcinoma) and 47 healthy controls. NLR and PLR were calculated by dividing the absolute number of neutrophils or platelets with the absolute number of lymphocytes. RESULTS:There were significant differences in both NLR and PLR (P<0.001) between all LC patients and the control group, but there were no differences between patients with different LC subtypes. Reciever operating characteristics analysis for NLR showed the optimal cut-off value of 2.71, with a sensitivity of 77.05% and specificity of 87.23%. The optimal cut-off value for PLR was 182.31, with a sensitivity of 51.09% and specificity of 91.49%. CONCLUSION:The results showed that the NLR and PLR may have added value in the early diagnosis of LC, but further research is needed to confirm these results.
journal_name
Croat Med Jjournal_title
Croatian medical journalauthors
Nikolić I,Kukulj S,Samaržija M,Jeleč V,Žarak M,Orehovec B,Taradi I,Romić D,Kolak T,Patrlj Ldoi
10.3325/cmj.2016.57.287subject
Has Abstractpub_date
2016-06-30 00:00:00pages
287-92issue
3eissn
0353-9504issn
1332-8166journal_volume
57pub_type
杂志文章abstract::A radical primary health care-oriented reform of the medical services in Albania is now under way, calling for adequate revision in medical education. The reform has started in 1994. In January 1997, the Department of Family Medicine at the Faculty of Medicine, University of Tirana, was established for the development...
journal_title:Croatian medical journal
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journal_title:Croatian medical journal
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abstract:AIM:To determine the diagnostic yield and criteria that could help to classify and interpret the copy number variations (CNVs) detected by chromosomal microarray (CMA) technique in patients with congenital and developmental abnormalities including dysmorphia, developmental delay (DD) or intellectual disability (ID), au...
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journal_title:Croatian medical journal
pub_type: 杂志文章,meta分析,评审
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doi:
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doi:
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doi:
更新日期:2007-10-01 00:00:00
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pub_type: 杂志文章
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doi:
更新日期:1998-06-01 00:00:00
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doi:
更新日期:2004-12-01 00:00:00
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doi:
更新日期:2000-12-01 00:00:00
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doi:
更新日期:2003-12-01 00:00:00
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journal_title:Croatian medical journal
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doi:
更新日期:2000-06-01 00:00:00
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journal_title:Croatian medical journal
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doi:
更新日期:2002-12-01 00:00:00
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journal_title:Croatian medical journal
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doi:
更新日期:1999-12-01 00:00:00
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journal_title:Croatian medical journal
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doi:
更新日期:2004-10-01 00:00:00
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更新日期:2006-06-01 00:00:00
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doi:
更新日期:2002-08-01 00:00:00
abstract:AIM:To assess the quality of diabetes care provided by family medicine teams in primary health centers in Bosnia and Herzegovina (BH) through a medical audit, addressing the extent to which clinical practice complied with pre-determined explicit criteria of long-term management. METHOD:Retrospective analysis included ...
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