Abstract:
AIM:To estimate the proportional contribution of influenza viruses (IV), parainfluenza viruses (PIV), adenoviruses (AV), and coronaviruses (CV) to the burden of severe acute lower respiratory infections (ALRI). METHODS:The review of the literature followed PRISMA guidelines. We included studies of hospitalized children aged 0-4 years with confirmed ALRI published between 1995 and 2011. A total of 51 studies were included in the final review, comprising 56091 hospitalized ALRI episodes. RESULTS:IV was detected in 3.0% (2.2%-4.0%) of all hospitalized ALRI cases, PIV in 2.7% (1.9%-3.7%), and AV in 5.8% (3.4%-9.1%). CV are technically difficult to culture, and they were detected in 4.8% of all hospitalized ALRI patients in one study. When respiratory syncytial virus (RSV) and less common viruses were included, at least one virus was detected in 50.4% (40.0%-60.7%) of all hospitalized severe ALRI episodes. Moreover, 21.9% (17.7%-26.4%) of these viral ALRI were mixed, including more than one viral pathogen. Among all severe ALRI with confirmed viral etiology, IV accounted for 7.0% (5.5%-8.7%), PIV for 5.8% (4.1%-7.7%), and AV for 8.8% (5.3%-13.0%). CV was found in 10.6% of virus-positive pneumonia patients in one study. CONCLUSIONS:This article provides the most comprehensive analysis of the contribution of four viral causes to severe ALRI to date. Our results can be used in further cost-effectiveness analyses of vaccine development and implementation for a number of respiratory viruses.
journal_name
Croat Med Jjournal_title
Croatian medical journalauthors
Lukšić I,Kearns PK,Scott F,Rudan I,Campbell H,Nair Hdoi
10.3325/cmj.2013.54.122subject
Has Abstractpub_date
2013-04-01 00:00:00pages
122-34issue
2eissn
0353-9504issn
1332-8166journal_volume
54pub_type
杂志文章,meta分析,评审abstract:AIM:To establish the incidence of tumors of the central nervous system (CNS) in the population of Labin area in Istria, Croatia, characterized by very little population migration. METHOD:We retrospectively analyzed data on 175 patients (102 men and 73 women) diagnosed with CNS tumor according to the World Health Organ...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract:AIM:Analysis of countertransference problems in the treatment of a heterogeneous group of war veterans. METHOD:The method used in this work was psychodynamic clinical observation and analysis of countertransference phenomena in group therapy. RESULTS:In the beginning of our work, we faced with a regressive group, whi...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract:AIM:To determine the stimulation site of both facial and hypoglossal nerves after transcranial magnetic stimulation. METHODS:After surgical exposure of the brainstem in 22 patients with intrinsic pontine (n=9) or medullary (n=13) tumors, the facial colliculus and the hypoglossal triangle were electrically stimulated. ...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:AIM:In an effort to help alleviate the lack of an adequate pediatric cardiac surgical service that existed in Croatia following 1991 the International Childrens Heart Foundation (ICHF) was asked to provide the necessary surgery. Initially, this project was undertaken as a humanitarian program to provide pediatric cardi...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract:AIM:To evaluate the effectiveness of suture anchors in the reconstruction of chronic collateral ligaments of fingers. METHODS:We treated 8 patients, 6 with chronic instability of the collateral ligament of the thumb and 2 with the instability of the fifth finger, using the Statak suture anchor. A stable joint was achi...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract:AIM:To assess the ability to work and employability of individuals taking part in opioid substitution treatment programs (OSTP). METHODS:The study was composed of two surveys. In the first survey, 237 of 480 patients enrolled in OSTP responded to the questionnaire about their employment status, opinion about employmen...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2008.49.842
更新日期:2008-12-01 00:00:00
abstract:AIM:To investigate what Zagreb University students think about professor-student dating. METHODS:We surveyed 500 students from ten different Zagreb University schools using anonymous questionnaires. Twenty-five female and 25 male students from each school were asked to assess professor-student dating as either accepta...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract:AIM:To investigate the characteristics and determine risk factors for hantanvirus infection in natural focus of hemorrhagic fever with renal syndrome (HFRS) on the Dinara Mountain, where outbreak of disease emerged among Croatian soldiers in 1995, and to describe the features of HFRS acquired on the Dinara mountain and...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::The generally accepted structure of a scientific paper is four sections, an introduction, a methods section, the results, and a discussion. This so-called IMRaD format is, with a few small variations, found in most research articles in biomedical journals. However, as a guide for someone writing up research data for t...
journal_title:Croatian medical journal
pub_type: 社论
doi:
更新日期:2002-06-01 00:00:00
abstract::The Croatian Pharmaceutical Sector Reform Project was one component of a larger Health Reform Project financed by the World Bank. The Croatian government was concerned that Croatia appeared to spend more money on medicinal drugs than most other countries in the region; that the price of drugs purchased in Croatia was ...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract:AIM:To evaluate scientific production among research fellows employed at the Zagreb University School of Medicine and identify factors associated with their scientific output. METHOD:We conducted a survey among research fellows and their mentors during June 2005. The main outcome measure was publication success, defin...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract:AIM:To compare morbidity and mortality of patients with severe intra-abdominal infections after two types of surgical treatment, on-demand ("wait and see") relaparotomy and modified planned relaparotomy. METHODS:We prospectively analyzed the outcomes of 65 patients with severe peritonitis surgically treated in two Cro...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2005-12-01 00:00:00
abstract::For more than a century, since the introduction of modern hernia repair by Basinni, technical aspects of hernia surgery have been surrounded by controversies. The purpose of this article is to examine these controversies with special attention to (a) mechanical versus degenerative nature of hernias, (b) traditional ti...
journal_title:Croatian medical journal
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
abstract:AIM:To determine changes in sexual behaviors and other relevant characteristics related to human immunodeficiency virus (HIV) and sexually transmitted infection (STI) risks among young Croatian adults. METHOD:We surveyed adults aged 18-24 in 2005 (n=1092) and 18-25 in 2010 (n=1005). Both samples were probabilistic and...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2011.52.458
更新日期:2011-08-15 00:00:00
abstract:AIM:To assess the diagnostic value of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in lung cancer (LC). We compared the ratios between healthy participants and all LC patients, as well patients with different pathohistological LC subtypes. METHODS:We retrieved the data on neutrophil, lym...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2016.57.287
更新日期:2016-06-30 00:00:00
abstract:AIM:To assess the usefulness of a DNA-based method for identifying mushroom species for application in forensic laboratory practice. METHODS:Two hundred twenty-one samples of clinical forensic material (dried mushrooms, food remains, stomach contents, feces, etc) were analyzed. ITS2 region of nuclear ribosomal DNA (nr...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2015.56.32
更新日期:2015-02-01 00:00:00
abstract::Botulinum neurotoxins (BoNTs) are the most lethal of known human toxins, exerting their actions by cleaving the soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptors (SNAREs) required for neurotransmitter release. Early detection of these toxins is important for appropriate medical treatment....
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2005-08-01 00:00:00
abstract:AIM:To examine the role of perceived stressfulness of trauma exposure and economic, social, occupational, educational, and familial adaptation after trauma in posttraumatic stress disorder (PTSD) and depression in displaced war survivors. METHODS:A cross-sectional survey was conducted between March 2000 and July 2002 ...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2011.52.709
更新日期:2011-12-15 00:00:00
abstract::Kidney transplantation is the most efficient method of renal replacement therapy. When this method is performed, native urinary bladder is the preferred urinary reservoir. However, in some patients with an anatomically and functionally abnormal lower urinary tract, the urinary bladder cannot be used for transplantatio...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2019-12-31 00:00:00
abstract::Hydrocephalus is a common brain disorder that is treated only with surgery. The basis for surgical treatment rests on the circulation theory. However, clinical and experimental data to substantiate circulation theory have remained inconclusive. In brain tissue and in the ventricles, we see that osmotic gradients drive...
journal_title:Croatian medical journal
pub_type: 杂志文章,评审
doi:10.3325/cmj.2014.55.366
更新日期:2014-08-28 00:00:00
abstract:AIM:To evaluate the administration of antipyretics to children with upper respiratory tract infections (URTI) by their parents or guardians without consultation with physicians, and compare epidemiological and clinical characteristics of patients who received antipyretics and of untreated patients. METHODS:A prospecti...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2011.52.48
更新日期:2011-02-01 00:00:00
abstract:AIM:To asses prevalence of essential arterial hypertension in family members of soldiers killed in 1992-1995 war in Bosnia and Herzegovina. METHODS:The study enrolled 1144 subjects who lost a family member in the war and 582 of their close neighbors who experienced no such loss. Data on their medical history and habit...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::Academic medicine is usually considered to be a tripartite composition of teaching, research, and health care services delivery or patient care. The meaning of each component varies with interpretation. Developing countries such as Malawi face particular challenges in the field of academic medicine, including research...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract:AIM:To analyze the incidence, transvaginal detection age, sonographic appearance, clinical course, and outcomes of pregnancy in cases with abnormal fetal brain structure and/or circulation, and to evaluate the clinical significance of sonographic abnormalities. METHODS:Serial observation of the fetal brain and intracr...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:AIM:To conduct developmental validation studies on a polymerase chain reaction (PCR) based short tandem repeat (STR) multiplex typing system, developed for the purpose of genetic individualization and parentage testing in domestic cat samples. METHODS:To evaluate reproducibility of the typing system, the multiplex was...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract:AIM:To test antinociceptive properties of botulinum toxin type A (BTX-A) in rats with carrageenan- and capsaicin-induced pain and inflammation. METHODS:Pain was provoked with carrageenan (1%) or capsaicin (0.1%) injection into the plantar surface of the rat paw-pad. The effect of BTX-A 5 U/kg on carrageenan- and capsa...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract:AIM:To evaluate clinical features, diagnosis, and treatment of oral cancer in Jordan. METHOD:We retrospectively analyzed the medical records 118 consecutive patients treated for oral cancer from 1989 until 1998. RESULTS:The age of the patients ranged from 35 to 90 years (median 62.5 years); three quarters were men. N...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:AIM:To evaluate the changes in the expression level of gonadal steroid, insulin, and leptin receptors in the brain of adult Sprague-Dawley female rats due to ovariectomy and/or chronic stress. METHODS:Sixteen-week-old ovariectomized and non-ovariectomized female Sprague-Dawley rats were divided in two groups and expos...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2016.57.194
更新日期:2016-04-23 00:00:00
abstract:AIM:To test the hypothesis that tSSEP findings reflect clinical and MRI MS lesions, the aim of this study was to investigate tSSEP changes in patients with clinically isolated syndrome (CIS) in relation to clinical and brainstem MRI findings. The second aim was to investigate whether the interpretation of the tSSEP res...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2016.57.558
更新日期:2016-12-31 00:00:00
abstract:AIM:To assess genetic diversity and genetic distances among isolated populations from Dagestan. METHODS:A cross-population genetic epidemiology design was applied in ethnically and demographically diverse isolates from Dagestan, some with more than 200 and some with less than 100 generations of demographical history s...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2006-08-01 00:00:00