Silencing of ABCG2 by MicroRNA-3163 Inhibits Multidrug Resistance in Retinoblastoma Cancer Stem Cells.

abstract：:p21 protein has been reported to be a critical downstream effector of p53 and a potent inhibitor of cyclin-dependent kinases. Thus, the p21 gene is thought to play a central role in tumor suppression. In this study we investigated p21 protein expression and mutation in gastric adenocarcinoma. A total of 76 primary gas...

journal_title：Journal of Korean medical science

authors： Park YE,Choi KC,Choi YH

更新日期：1998-10-01 00:00:00

abstract：:Despite the increasing use of the rectal balloon in prostate cancer radiotherapy, many issues still remain to be verified objectively including its positional reproducibility and relevance to treatment morbidity. We have developed a custom rectal balloon that has a scale indicating the depth of insertion and dilates s...

journal_title：Journal of Korean medical science

authors： Cho JH,Lee CG,Kang DR,Kim J,Lee S,Suh CO,Seong J,Suh YG,Lee I,Kim GE

更新日期：2009-10-01 00:00:00

abstract：:Since Zika virus has been spreading rapidly in the Americas from 2015, the outbreak of Zika virus infection becomes a global health emergency because it can cause neurological complications and adverse fetal outcome including microcephaly. Here, we report clinical manifestations and virus isolation findings from a cas...

journal_title：Journal of Korean medical science

authors： Jang HC,Park WB,Kim UJ,Chun JY,Choi SJ,Choe PG,Jung SI,Jee Y,Kim NJ,Choi EH,Oh MD

更新日期：2016-07-01 00:00:00

abstract：:A series of five endodermal sinus tumors was studied for their cytoskeletal and other phenotypic markers. They included 2 ovarian, 2 testicular, and 1 inguinal tumors. The cytoskeletal expression was also studied by gel electrophoresis and immunoblotting. Every tumor was diffusely and strongly immunostained for cytoke...

journal_title：Journal of Korean medical science

authors： Chung J,Gong G,Cho J,Choe G,Yu E,Lee I

更新日期：1994-04-01 00:00:00

abstract：:[This corrects the article on p. 1482 in vol. 29, PMID: 25408578.]. ...

journal_title：Journal of Korean medical science

authors： Choi EJ,Kim SA,Kim NR,Rhee JA,Yun YW,Shin MH

更新日期：2015-01-01 00:00:00

abstract：:A patient with a sciatic artery aneurysm, which is so rare that only 31 cases have been reported in the literature to date, was treated successfully with transcatheter arterial embolization (TAE) alone. Potentially risky and difficult surgery was avoided. This was the first trial with a good result. TAE alone is simpl...

journal_title：Journal of Korean medical science

authors： Song HY,Chung GH,Han YM

更新日期：1992-09-01 00:00:00

abstract：:The combined use of a drug-eluting balloon (DEB) and a bare metal stent (BMS) for the treatment of de novo non-small vessel coronary artery diseases (CAD) remains to be evaluated. We investigated the efficacy of a sequential treatment using a DEB together with a BMS implantation in comparison to a zotarolimus-eluting ...

journal_title：Journal of Korean medical science

authors： Chae IH,Yoon CH,Park JJ,Oh IY,Suh JW,Cho YS,Youn TJ,Choi DJ

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to present and analyze, for the first time, the results of a government-supported nationwide newborn hearing screening (NHS) pilot project in the 17 major cities and provinces of Korea. METHODS:We analyzed a nationwide NHS database of 344,955 newborns in the pilot project from 2014...

journal_title：Journal of Korean medical science

authors： Chung YS,Oh SH,Park SK

更新日期：2020-08-10 00:00:00

abstract：:We examined the relationship of high emotional demands and low job control to suicidal ideation among service and sales workers in Korea. A total of 1,995 service and sales workers participated in this study. Suicidal ideation and level of emotional demand and job control were assessed by self-reported questionnaire i...

journal_title：Journal of Korean medical science

authors： Yoon JH,Jeung D,Chang SJ

更新日期：2016-07-01 00:00:00

abstract：Background:The role of antidepressants (ADs) in bipolar disorder is long-standing controversial issue in psychiatry. Many clinicians have used ADs as a treatment for bipolar depression, and the selection of therapeutic agents is very diverse and inconsistent. This study aimed to examine recent AD prescription patterns ...

journal_title：Journal of Korean medical science

authors： Yoon W,Shon SH,Hong Y,Joo YH,Lee JS

更新日期：2018-10-19 00:00:00

abstract：:Head and neck metastasis from glioblastoma is rare event usually seen in patients with previous and repeated surgery. We present the case of a 35 yr-old-female suffering from metastatic glioblastoma in cervical lymph node that was diagnosed by fine needle aspiration. During the last 4 yr, she had four separate craniot...

journal_title：Journal of Korean medical science

authors： Moon KS,Jung S,Lee MC,Kim IY,Kim HW,Lee JK,Kim TS

更新日期：2004-12-01 00:00:00

abstract：:We aimed to elucidate whether the eNOS T-786C mutant allele is implicated in subarachnoid hemorrhage (SAH) susceptibility or vasospasm after SAH, and whether the mutant allele is differentially expressed in those with small and large ruptured aneurysms in Korean population. 136 consecutive patients diagnosed with aneu...

journal_title：Journal of Korean medical science

authors： Song MK,Kim MK,Kim TS,Joo SP,Park MS,Kim BC,Cho KH

更新日期：2006-10-01 00:00:00

abstract：:[This corrects the article e66 in vol. 34, PMID: 30833883.]. ...

journal_title：Journal of Korean medical science

authors：

更新日期：2019-03-06 00:00:00

abstract：:Our study aimed to examine the knowledge and attitude of nursing personnel toward depression in general hospitals of Korea. A total of 851 nursing personnel enrolled at four university-affiliated general hospitals completed self-report questionnaires. Chi-square tests were used to compare the knowledge and attitude of...

journal_title：Journal of Korean medical science

authors： Park SC,Lee HY,Lee DW,Hahn SW,Park SH,Kim YJ,Choi JS,Lee HS,Lee SI,Na KS,Jung SW,Shim SH,Choi J,Paik JW,Kwon YJ

更新日期：2015-07-01 00:00:00

abstract：:The increasing interest in healthcare and health screening events is revealing additional cases of asymptomatic isolated microscopic hematuria (IMH). However, a consensus of the evaluation and explanation of the IMH prognosis is controversial among physicians. Here, we present the natural course of IMH together with t...

journal_title：Journal of Korean medical science

authors： Lee HM,Hyun JI,Min JW,Lee K,Kim YK,Choi EJ,Song HC

更新日期：2016-06-01 00:00:00

abstract：Background:We aimed to estimate whether elevated levels of complement C3a and C5a in amniotic fluid (AF) are independently associated with increased risks of intra-amniotic infection and/or inflammation (IAI) and spontaneous preterm delivery (SPTD) in women with cervical insufficiency or a short cervix (≤ 25 mm). Meth...

journal_title：Journal of Korean medical science

authors： Kim YM,Park KH,Park H,Yoo HN,Kook SY,Jeon SJ

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:Mechanism and predictive biomarkers for tyrosine kinase inhibitor (TKI) resistance of advanced clear cell renal cell carcinoma (ccRCC) have not been fully evaluated. METHODS:We performed gene expression profiling on samples from an acquired TKI resistance cohort that consisted of 10 cases of TKI-treated ccR...

journal_title：Journal of Korean medical science

authors： Hwang HS,Park YY,Shin SJ,Go H,Park JM,Yoon SY,Lee JL,Cho YM

更新日期：2020-02-10 00:00:00

abstract：:An experiment was designed to investigate the reaction mechanism of AP (apurinic or apyrimidinic) DNA endonucleases (APcI, APcII, APcIII) purified from rat liver chromatin. Sulfhydryl compounds (2-mercaptoethanol, dithiothreitol) brought about optimal activities of AP DNA endonucleases and N-ethylmaleimide or HgCl2 in...

journal_title：Journal of Korean medical science

authors： Kim YS,Kim JW,Lee SE,Oh SH

更新日期：1990-09-01 00:00:00

abstract：:Pulmonary bronchogenic cyst in adults is rare and the typical appearance is a sharply circumscribed, round or oval nodule or mass, usually in the medial third of the lungs. Bronchial polyps are rare histopathologically distinct nonneoplastic endobronchial lesions and are classified as multiple papillomas, solitary pap...

journal_title：Journal of Korean medical science

authors： Kim JH,Jang AS,Park JS,Lee JH,Park SW,Koh ES,Park JS,Park CS

更新日期：2005-10-01 00:00:00

abstract：:Several factors can affect the perioperative immune function. We evaluated the effect of propofol and desflurane anesthesia on the surgery-induced immune perturbation in patients undergoing breast cancer surgery. The patients were randomly assigned to receive propofol (n = 20) or desflurane (n = 20) anesthesia. The to...

journal_title：Journal of Korean medical science

authors： Woo JH,Baik HJ,Kim CH,Chung RK,Kim DY,Lee GY,Chun EH

更新日期：2015-10-01 00:00:00

abstract：:This observational study aimed at evaluating recent superwarfarin intoxication of Korean patients. Ten patients were diagnosed as or highly suspicious for superwarfarin intoxication. Case report forms described by attending hematologists of the patients were collected and analyzed. Bleeding symptoms were varied among ...

journal_title：Journal of Korean medical science

authors： Hong J,Yhim HY,Bang SM,Bae SH,Yuh YJ,Yoon SS,Yoon HJ,Kim ST,Chi HS

更新日期：2010-12-01 00:00:00

abstract：:The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Korean workers. In 1995, 23 of the 33 workers (25 female and 8...

journal_title：Journal of Korean medical science

authors： Park J,Shin KS,Kim Y

更新日期：2010-12-01 00:00:00

abstract：:We examined the possible anti-inflammatory mechanisms of gabapentin in the attenuation of neuropathic pain and the interaction between the anti-allodynic effects of gabapentin and interleukin-10 (IL-10) expression in a rat model of neuropathic pain. The anti-allodynic effect of intrathecal gabapentin was examined over...

journal_title：Journal of Korean medical science

authors： Lee BS,Jun IG,Kim SH,Park JY

更新日期：2013-02-01 00:00:00

abstract：:Oxysterol 7α-hydroxylase deficiency is a very rare liver disease categorized as inborn errors of bile acid synthesis, caused by CYP7B1 mutations. As it may cause rapid progression to end-stage liver disease even in early infancy, a high index of suspicion is required to prevent fatal outcomes. We describe the case of ...

journal_title：Journal of Korean medical science

authors： Hong J,Oh SH,Yoo HW,Nittono H,Kimura A,Kim KM

更新日期：2018-11-22 00:00:00

abstract：:Neuroblastomas originating from different sites might have different clinical and biological characteristics. In the present study, the clinical (age, sex and stage) and biological (N-myc amplification, Shimada pathology and levels of lactate dehydrogenase, ferritin and neuron-specific enolase) characteristics of pati...

journal_title：Journal of Korean medical science

authors： Sung KW,Yoo KH,Koo HH,Kim JY,Cho EJ,Seo YL,Kim J,Lee SK

更新日期：2009-06-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) strains may cause serious nosocomial infections, including pneumonia and septicemia. The rate of methicillin-resistance among S. aureus isolates in Korea is over 50%. In this study, 90 MRSA isolates from Kyung Hee University Hospital were characterized employing bacte...

journal_title：Journal of Korean medical science

authors： Lee HJ,Suh JT,Kim YS,Lenz W,Bierbaum G,Schaal KP

更新日期：2001-08-01 00:00:00

abstract：:This study was done to determine whether recombinant human erythropoietin (rhEPO) treatment could attenuate hyperoxia-induced lung injury, and if so, whether this protective effect is mediated by the down-modulation of inflammation in neonatal rats. Newborn Sprague Dawley rat pups were subjected to 14 days of hyperoxi...

journal_title：Journal of Korean medical science

authors： Lee JH,Sung DK,Koo SH,Shin BK,Hong YS,Son CS,Lee JW,Chang YS,Park WS

更新日期：2007-12-01 00:00:00

abstract：:Clear-cell chondrosarcoma, a recently specified entity, is a low-grade malignant tumor and has characteristic clinical, roentgenographic and pathologic findings which separate it from conventional chondrosarcoma and other benign tumors. Therefore, correct diagnosis is important from the viewpoint of both prognosis and...

journal_title：Journal of Korean medical science

authors： Lee SD,Ahn GH,Chi JG,Ham EK

更新日期：1989-09-01 00:00:00

abstract：:Emergency surgical repair for acute traumatic aortic ruptures has been associated with a high peri-procedural mortality rate. Endovascular stent-grafting, as a less invasive procedure, has shown encouraging results. This report describes a patient with a short landing zone, who was treated by transposing the supra-aor...

journal_title：Journal of Korean medical science

authors： Ryu YG,Choo SJ,Lim JY,Yoon HK,Chung CH

更新日期：2010-01-01 00:00:00

abstract：:Testicular torsion is a surgical emergency in the field of urology. Knowledge of the epidemiology and pathophysiology is significant to an urologist. However, the epidemiology of testicular torsion in Korea has not been studied. We performed a nationwide epidemiological study to improve knowledge of the epidemiology o...

journal_title：Journal of Korean medical science

authors： Lee SM,Huh JS,Baek M,Yoo KH,Min GE,Lee HL,Lee DG

更新日期：2014-12-01 00:00:00