Abstract：
:The combined use of a drug-eluting balloon (DEB) and a bare metal stent (BMS) for the treatment of de novo non-small vessel coronary artery diseases (CAD) remains to be evaluated. We investigated the efficacy of a sequential treatment using a DEB together with a BMS implantation in comparison to a zotarolimus-eluting stent (ZES). This study was a prospective, randomized, open-label study. We designed it to demonstrate the non-inferiority of a sequential treatment using a DEB first followed by a BMS (DEB + BMS) compared with the use of a ZES. The primary endpoint was in-segment late loss (LL) at 9 months measured by quantitative coronary angiography (QCA). A total of 180 patients were enrolled in the study. The 9-month follow-up angiography was performed in 72 patients with DEB + BMS and 74 patients with ZES. When comparing the DEB + BMS results with the ZES ones, LL was 0.50 ± 0.46 mm in DEB + BMS patients vs. 0.21 ± 0.44 mm in ZES patients (P < 0.001). The mean difference of the LL was 0.31 mm, which was larger than the prespecified non-inferiority margin of 0.19 mm, and the 2-sided 95% confidence interval was 0.15-0.48. The clinical outcomes were not significantly different. In conclusion, the DEB + BMS strategy is inferior to the ZES one in terms of the LL result at 9 months. The DEB strategy for de novo coronary artery lesions needs to be improved for it to become an alternative treatment option.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Chae IH,Yoon CH,Park JJ,Oh IY,Suh JW,Cho YS,Youn TJ,Choi DJdoi
10.3346/jkms.2017.32.6.933subject
Has Abstractpub_date
2017-06-01 00:00:00pages
933-941issue
6eissn
1011-8934issn
1598-6357pii
32.933journal_volume
32pub_type
杂志文章,随机对照试验abstract：:Japanese encephalitis (JE) cases have been increasingly reported recently especially in Seoul and its vicinity. Pigs are known as amplifying host of JE virus (JEV), but do not play an important role in these recent events because pig-breeding is not common in Seoul. The distribution and the density of migratory birds ...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2018.33.e70
更新日期：2018-02-26 00:00:00
abstract：:Fracture of femur without evidence of severe osteoporosis rarely occurs as a result of minor external force such as a gentle passive or an active range of motion exercises. We report two cases of femoral shaft fracture occurred at the tip of heterotopic ossification of femur by a minor external force, in which the inv...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.1998.13.4.431
更新日期：1998-08-01 00:00:00
abstract：:Middle East respiratory syndrome (MERS) is a lethal respiratory disease - caused by MERS-coronavirus (MERS-CoV) which was first identified in 2012. Especially, pregnant women can be expected as highly vulnerable candidates for this viral infection. In May 2015, this virus was spread in Korea and a pregnant woman was c...
journal_title：Journal of Korean medical science
pub_type：
doi：10.3346/jkms.2017.32.10.1717
更新日期：2017-10-01 00:00:00
abstract：:Low quality clinical trials have a possibility to have errors in the process of deriving the results and therefore distort the study. Quality assessment of clinical trial is necessary in order to prevent any clinical application erroneous results is important. Randomized controlled trial (RCT) is a design for evaluate...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2012.27.9.973
更新日期：2012-09-01 00:00:00
abstract：:Local epidemiologic data on the etiologies of patients hospitalized with community-acquired pneumonia (CAP) is needed to develop guidelines for clinical practice. This study was conducted prospectively to determine the proportion of atypical bacterial pathogens in adults patients hospitalized with CAP in Korea between...
journal_title：Journal of Korean medical science
pub_type： 杂志文章,多中心研究
doi：10.3346/jkms.2006.21.4.602
更新日期：2006-08-01 00:00:00
abstract：:Obese subjects are more prone to sudden deaths and arrhythmias than non-obese subjects. Heart rate turbulence (HRT) impairment reflects cardiac autonomic dysfunction, in particular impaired baroreflex sensitivity and reduced parasympathetic activity. Our aim was to evaluate the cardiac autonomic function in obesity by...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2007.22.4.629
更新日期：2007-08-01 00:00:00
abstract：:Acute kidney injury (AKI) is closely associated with the mortality of hospitalized patients and long-term development of chronic kidney disease, especially in children. The purpose of our study was to assess the evidence of contrast-induced AKI after cardiac catheterization in children with heart disease and evaluate ...
journal_title：Journal of Korean medical science
pub_type： 临床试验,杂志文章
doi：10.3346/jkms.2014.29.8.1102
更新日期：2014-08-01 00:00:00
abstract：:Histiocytic sarcoma (HS) is a very rare neoplasm that often shows an aggressive clinical course and systemic symptoms, such as fever, weight loss, adenopathy, hepatosplenomegaly and pancytopenia. It may present as localized or disseminated disease. We describe here a 63-yr-old male who manifested systemic symptoms, in...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2010.25.2.313
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:On February 21, 2020, 2 coronavirus disease 2019 (COVID-19) cases in pilgrim travelers from Korea to Israel were identified. We investigated the source of infection, clinical features of COVID-19, and transmission potential of presymptomatic and asymptomatic cases. METHODS:All 39 pilgrim travelers were aggr...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2020.35.e424
更新日期：2020-12-14 00:00:00
abstract：:The purpose of the current study was to propose a Korean-specific parameter set for calculating the risk of Down syndrome in the second trimester of pregnancy and to determine the screening performances of triple and quadruple tests in Korean women. Using the data on triple or quadruple screening from three hospitals ...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2011.26.12.1619
更新日期：2011-12-01 00:00:00
abstract：:Deposition of basement membrane extracellular matrix is influenced by adjacent tumor cells, and in some cases, the pattern of type IV collagen deposit is characteristic in malignant tumors. In this report, we analyzed the difference in type IV collagen deposition patterns between benign and malignant phyllodes tumors ...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.1992.7.4.360
更新日期：1992-12-01 00:00:00
abstract：:Allergen-specific immunotherapy (SIT) reduces allergen specific IgE (sIgE) levels and achieves clinical and immunological tolerance by modulating innate and adaptive immunological responses. Increased temperature and CO2 concentrations caused by climate changes contribute to an increase of pollen count and allergenici...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2014.29.7.1025
更新日期：2014-07-01 00:00:00
abstract：:We evaluated alcohol consumption and alcohol-related problems in Korean adults by evaluating alcohol consumption and responses to the CAGE questionnaire obtained from the second Korea National Health and Nutrition Examination Survey. The age-adjusted prevalence of males who consumed 0, 0.1-20, 20.1-40, or >40 g/day of...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2008.23.2.199
更新日期：2008-04-01 00:00:00
abstract：:The permanent impairment evaluation for children in developmental stage is very difficult and it is even impossible in some cases. The impairment evaluation for developing children has not yet been included in the guideline of the American Medical Association. Due to frequent medical and social demands in Korea, we de...
journal_title：Journal of Korean medical science
pub_type： 杂志文章,实务指引
doi：10.3346/jkms.2009.24.S2.S323
更新日期：2009-05-01 00:00:00
abstract：:The rapid increases in childhood obesity and physical inactivity are linked to the incidence of diabetes among young individuals. However, few studies have evaluated the prevalence of diabetes among this population. Therefore, we used Korea National Health and Nutrition Examination Survey (KNHANES) data to evaluate th...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2017.32.12.1984
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to identify the characteristics of injuries of school-aged children transported via emergency medical services (EMS) that occurred in schools by comparing with injuries that occurred outside of school. METHODS:Data from the 119 EMS from 2012 to 2014 were analyzed. School and no...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2018.33.e73
更新日期：2018-03-05 00:00:00
abstract：:This study examined the normal ranges and the determinants for various parameters of the short-term heart rate variability (HRV) measurements in a large Korean sample of healthy people. HRV measurements were obtained in 2,748 healthy men and 735 healthy women 18-65 yr of age. The mean total power (TP), low frequency (...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2011.26.10.1293
更新日期：2011-10-01 00:00:00
abstract：:Despite the increasing use of the rectal balloon in prostate cancer radiotherapy, many issues still remain to be verified objectively including its positional reproducibility and relevance to treatment morbidity. We have developed a custom rectal balloon that has a scale indicating the depth of insertion and dilates s...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2009.24.5.894
更新日期：2009-10-01 00:00:00
abstract：Background:The aim of the study was to examine the characteristics of alpha wave peak frequency, power, and coherence in patients with schizophrenia. Methods:Thirty-one patients with schizophrenia and age- and sex-matched subjects with no psychopathology were enrolled. All study participants underwent quantitative ele...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2018.33.e179
更新日期：2018-05-17 00:00:00
abstract：:Our study aimed to examine the knowledge and attitude of nursing personnel toward depression in general hospitals of Korea. A total of 851 nursing personnel enrolled at four university-affiliated general hospitals completed self-report questionnaires. Chi-square tests were used to compare the knowledge and attitude of...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2015.30.7.953
更新日期：2015-07-01 00:00:00
abstract：:Pulmonary bronchogenic cyst in adults is rare and the typical appearance is a sharply circumscribed, round or oval nodule or mass, usually in the medial third of the lungs. Bronchial polyps are rare histopathologically distinct nonneoplastic endobronchial lesions and are classified as multiple papillomas, solitary pap...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2005.20.5.892
更新日期：2005-10-01 00:00:00
abstract：:Accessory ovary is a rare gynecologic condition, and tumors arising in accessory ovaries are extremely rare. Accessory ovary may result from separation of migrating ovaries during embryogenesis and injuries such as inflammation and operation on normal ovary. Congenital malformations, most frequently malformations of t...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2004.19.3.474
更新日期：2004-06-01 00:00:00
abstract：:A nation-wide survey was conducted to estimate the prevalence of otitis media and allied diseases through physical examination by otolaryngologic doctors from July to October, 1991. A sample study population was selected from a panel to be representative of the Korean population by multistage clustered and stratified ...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.1993.8.1.34
更新日期：1993-02-01 00:00:00
abstract：:We describe a 51-yr-old man presenting with syncope due to torsade de pointes. The torsade de pointes was refractory to conventional medical therapy, including infusion of isoproterenol, MgSO4, potassium, lidocaine, and amiodarone. His past history, physical findings, and hormone study confirmed that QT prolongation w...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2001.16.3.355
更新日期：2001-06-01 00:00:00
abstract：:We aimed to know the risk-stratification-based prevalence of bacterial contamination of ambulance vehicle surfaces, equipment, and materials. This study was performed in a metropolitan area with fire-based single-tiered Basic Life Support ambulances. Total 13 out of 117 ambulances (11.1%) were sampled and 33 sites per...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2011.26.1.124
更新日期：2011-01-01 00:00:00
abstract：:The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort ...
journal_title：Journal of Korean medical science
pub_type： 杂志文章,多中心研究
doi：10.3346/jkms.2014.29.9.1226
更新日期：2014-09-01 00:00:00
abstract：:We reviewed dinical, histological and ultrastructural findings of 124 cases of sural nerve biopsy specimens to delineate the trends of peripheral nerve diseases in our institute. Eighty-one were men and 43 were women. We categorized them into five groups: specific diagnosis (66 cases, 53.2%), axonal degeneration type ...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2000.15.2.211
更新日期：2000-04-01 00:00:00
abstract：:Effects of pH on vascular tone and L-type Ca2+ channels were investigated using Mulvany myograph and voltage-clamp technique in rabbit basilar arteries. In rabbit basilar arteries, high K+ produced tonic contractions by 11+/-0.6 mN (mean+/-S.E.,n=19). When extracellular pH (pHo) was changed from control 7.4 to 7.9 ([a...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2004.19.1.42
更新日期：2004-02-01 00:00:00
abstract：:A cadaveric study was performed to investigate the relationship between disc degeneration and morphological changes in the intervertebral foramen of cervical spine, including the effect on the nerve root. Seven fresh frozen human cadavers were dissected from C1 to T1, preserving the ligaments, capsules, intervertebral...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2004.19.1.101
更新日期：2004-02-01 00:00:00
abstract：:Inflammatory myofibroblastic tumors (IMTs) are benign neoplasms that can occur at different anatomic sites with nonspecific clinical symptoms. A 48-yr-old woman presented with a 2-month history of a relapsed oral ulcer, progressive dyspnea, and a thoracic pain induced by breathing. A tumorous mass was noticed in the r...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2007.22.4.735
更新日期：2007-08-01 00:00:00
