Abstract:
:The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Korean workers. In 1995, 23 of the 33 workers (25 female and 8 male workers) who were exposed to 2-bromopropane during the assembly of tactile switch parts developed reproductive and/or hematopoietic disorders. A total of 17 (68%) workers were diagnosed with ovarian failure. Two of the eight male workers experienced azoospermia and four workers experienced some degree of oligospermia or reduced sperm motility. In summary, 2-bromopropane poisoning caused severe reproductive effects in Korean workers. The prognosis was poor for reproductive dysfunction. A few cases of occupational bladder cancer have been reported in Korea, whereas other cancers of the urinary tract have not been reported after occupational exposure. A few cases of benzidine-induced cancer have been reported in Korea and 592 workers in Japan have received compensation for benzidine and β-naphthylamine-induced cancer. In conclusion, a few cases of benzidine-induced occupational bladder cancer have been reported in Korea. However, benzidine-induced bladder cancer will likely be an important occupational health issue in Korea in the coming years.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Park J,Shin KS,Kim Ydoi
10.3346/jkms.2010.25.S.S41subject
Has Abstractpub_date
2010-12-01 00:00:00pages
S41-5issue
Suppleissn
1011-8934issn
1598-6357journal_volume
25pub_type
杂志文章,评审abstract::Thirty-six cases of necrotizing lymphadenitis--including 33 cases of unknown etiology, 1 typhoid lymphadenopathy, and 2 cases of suspicious lupus lymphadenopathy--were clinico-pathologically reviewed and analyzed with immunostaining for s-100 and lysozyme. All cases histologically showed architectural effacement by pa...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1991.6.1.55
更新日期:1991-03-01 00:00:00
abstract::To determine whether the p53 expression might be a predictor for treatment response and overall survival in nodal non-Hodgkin's lymphoma (NHL), we analyzed the expression of p53 in 69 NHL patients. p53 protein expression was analyzed by immunohistochemistry with long-term follow up (1-148 months: median 12.2). p53 exp...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2000.15.1.59
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Although hypertension (HTN) is a well-established major risk factor for renal progression in patients with chronic kidney disease (CKD), few studies investigating its role in renal deterioration in the general population with normal renal function (NRF) have been published. Here, we analyzed the correlation ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2020.35.e312
更新日期:2020-08-31 00:00:00
abstract::We investigated the incidence of unsuspected gallbladder (GB) carcinomas in a total of 527 consecutive GB specimens resected for benign biliary disease and their clinicopathological features. The GBs were examined microscopically using stepwise tissue sections at 5 mm interval. Clinical and pathological findings were ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1997.12.6.519
更新日期:1997-12-01 00:00:00
abstract::Various types of stress affect mental health in the form of mood disorders, anxiety disorders, and suicidal ideation. Recently, the increasing suicide rate in the working-age population has become a major mental health concern in Korea. Thus, we investigated what kind of stress influence depression, anxiety, and suici...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2017.32.5.843
更新日期:2017-05-01 00:00:00
abstract::The World Health Organization (WHO) enzyme-linked immunosorbent assay (ELISA) guideline is currently accepted as the gold standard for the evaluation of immunoglobulin G (IgG) antibodies specific to pneumococcal capsular polysaccharide. We conducted validation of the WHO ELISA for 7 pneumococcal serotypes (4, 6B, 9V, ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2017.32.10.1581
更新日期:2017-10-01 00:00:00
abstract::The study of cancer in patients treated with dialysis in Korea has not been reported. The aim of this study was to investigate the incidence and mortality of cancer among patients on dialysis in Korea. The study subjects were 106 cancer patients (2.3%) out of 4,562 end-stage renal disease (ESRD) patients maintained on...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2009.24.S1.S95
更新日期:2009-01-01 00:00:00
abstract::Using the methods of restriction fragment length polymorphism (RFLP) and single strand conformation polymorphism (SSCP) analyses, we have examined 33 cases of human gliomas with various malignant grades to detect the deletions of putative tumor suppressor gene loci, chromosome 10, 13q(retinoblastoma gene, Rb), 17p, an...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1995.10.6.442
更新日期:1995-12-01 00:00:00
abstract::Despite high prevalence of upper urinary tract calculi (UUTC), there are few studies regarding patterns of care in Asian populations. We investigated treatment patterns and time trends in patients with newly diagnosed UUTC in Korea using the National Health Insurance database that includes de-identified claims from a ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2016.31.12.1989
更新日期:2016-12-01 00:00:00
abstract::Multiple epiphyseal dysplasia is caused by heterogeneous genotypes involving more than six genes. Recessive mutations in the DTDST gene cause a phenotype of recessive multiple epiphyseal dysplasia (rMED). The authors report a 9-yr old Korean girl with the rMED phenotype having novel compound heterozygous mutations in ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2010.25.7.1105
更新日期:2010-07-01 00:00:00
abstract::Pulmonary bronchogenic cyst in adults is rare and the typical appearance is a sharply circumscribed, round or oval nodule or mass, usually in the medial third of the lungs. Bronchial polyps are rare histopathologically distinct nonneoplastic endobronchial lesions and are classified as multiple papillomas, solitary pap...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2005.20.5.892
更新日期:2005-10-01 00:00:00
abstract::When in need of medical treatment, Korean citizens have a choice of practitioners of western medicine (WM) or Traditional Korean Medicine (TKM). However, the two branches frequently conflict with one another, particularly with regard to mental disorders. This study was designed to compare the utilization of WM and TKM...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2016.31.5.770
更新日期:2016-05-01 00:00:00
abstract::Lyme disease is a vector-borne infection, primarily transmitted by Ixodes ticks, and caused by Borrelia burgdorferi. It has a wide distribution in the northern hemisphere. In Korea, however, only one human case has been reported, although B. burgdorferi was isolated from the vector tick I. persulcatus in the region. A...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1999.14.1.85
更新日期:1999-02-01 00:00:00
abstract::The Rejuran® is a new filler product made from purified polynucleotides. Here we present data from an animal study and a clinical trial to examine the durability, efficacy and safety of the Rejuran® on crow's feet. For the animal study, 25 mice were divided into three groups: Group 1 received phosphate buffered saline...
journal_title:Journal of Korean medical science
pub_type: 杂志文章,随机对照试验,收录出版
doi:10.3346/jkms.2014.29.S3.S201
更新日期:2014-11-01 00:00:00
abstract:Background:The role of antidepressants (ADs) in bipolar disorder is long-standing controversial issue in psychiatry. Many clinicians have used ADs as a treatment for bipolar depression, and the selection of therapeutic agents is very diverse and inconsistent. This study aimed to examine recent AD prescription patterns ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2018.33.e290
更新日期:2018-10-19 00:00:00
abstract::A 17-yr-old young woman was referred to our hospital with a 2-yr history of claudication of the lower extremities and severe arterial hypertension. Physical examination revealed significantly different blood pressures between both arms (160/92 and 180/95 mmHg) and legs (92/61 and 82/57 mmHg). The hematological and bio...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2008.23.3.551
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Routine blood pressure (BP) measurement is recommended to begin at 3 years of age, but there are no national BP reference values for Korean children less than 7 years of age. Therefore, we developed sex-, age-, and height-specific BP reference values for non-overweight children aged 3-9 years. METHODS:We an...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2020.35.e91
更新日期:2020-03-30 00:00:00
abstract:Background:We aimed to estimate whether elevated levels of complement C3a and C5a in amniotic fluid (AF) are independently associated with increased risks of intra-amniotic infection and/or inflammation (IAI) and spontaneous preterm delivery (SPTD) in women with cervical insufficiency or a short cervix (≤ 25 mm). Meth...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2018.33.e220
更新日期:2018-07-05 00:00:00
abstract::Hyalinizing spindle cell tumor with giant rosettes (HSCTGR) is a recently described tumor, which is regarded as an unusual variant of low-grade fibromyxoid sarcoma. Proof of a metastatic potential was lacking. The patient in the report was a 35-yr-old woman who showed multiple bilateral pulmonary nodules with massive ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2004.19.4.619
更新日期:2004-08-01 00:00:00
abstract::Current and primary treatment modality in overactive bladder includes the administration of anticholinergics. The demand for new agents has been rising since anticholinergics have proven to come with many side effects. This study was designed to investigate the effects of ylang-ylang essential oil (YYEO) on the relaxa...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2003.18.3.409
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to identify the characteristics of injuries of school-aged children transported via emergency medical services (EMS) that occurred in schools by comparing with injuries that occurred outside of school. METHODS:Data from the 119 EMS from 2012 to 2014 were analyzed. School and no...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2018.33.e73
更新日期:2018-03-05 00:00:00
abstract::As of April 18, 2020, there have been a total of 10,653 confirmed cases and 232 deaths due to coronavirus disease 2019 (COVID-19) in Korea. The pathogen spread quickly, and the outbreak caused nationwide anxiety and shock. This study presented the anecdotal records that provided a detailed process of the multidiscipli...
journal_title:Journal of Korean medical science
pub_type: 杂志文章,评审
doi:10.3346/jkms.2020.35.e211
更新日期:2020-06-08 00:00:00
abstract::Aim of this study was to compare the outcomes of transplantation by donor source and to help select the best alternative donor in children with leukemia. Donor sources included matched related donor (MRD, n = 35), allele-matched unrelated donor (M-UD, n = 10) or -mismatched (MM)-UD (n = 13) or unrelated umbilical cord...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2011.26.12.1548
更新日期:2011-12-01 00:00:00
abstract::Vivax malaria was endemic on the Korean peninsula for many centuries until the late 1970's when the Republic of Korea (ROK) was declared "malaria free". Since its re-emergence in 1993, the number of malaria cases in the military increased exponentially through 2000 near the demilitarized zone. Chemoprophylaxis with ch...
journal_title:Journal of Korean medical science
pub_type: 临床试验,杂志文章
doi:10.3346/jkms.2005.20.5.707
更新日期:2005-10-01 00:00:00
abstract::This study was undertaken to evaluate the incidence and risk factors associated with relative adrenal insufficiency (RAI) in Korean critically-ill patients. All patients who were admitted to the Medical Intensive Care Unit (MICU) of Samsung Medical Center between January 1, 2006 and April 30, 2007 were prospectively e...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2009.24.4.668
更新日期:2009-08-01 00:00:00
abstract::In 2010, we proposed the first Korean Guidelines for the Prevention of Venous Thromboembolism (VTE). It was applicable to Korean patients, by modifying the contents of the second edition of the Japanese guidelines for the prevention of VTE and the 8th edition of the American College of Chest Physicians (ACCP) evidence...
journal_title:Journal of Korean medical science
pub_type: 杂志文章,实务指引
doi:10.3346/jkms.2014.29.2.164
更新日期:2014-02-01 00:00:00
abstract::Childhood kidney tumors seldom metastasize into the cranial cavity unless it is a special histological variant. We report a 4-year-old boy with multiple intracranial metastases in the left parietotemporal and right cerebellar area from primary clear cell sarcoma of the kidney without evidence of bony metastases. Metas...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1997.12.5.473
更新日期:1997-10-01 00:00:00
abstract::Inflammatory myofibroblastic tumors (IMTs) are benign neoplasms that can occur at different anatomic sites with nonspecific clinical symptoms. A 48-yr-old woman presented with a 2-month history of a relapsed oral ulcer, progressive dyspnea, and a thoracic pain induced by breathing. A tumorous mass was noticed in the r...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2007.22.4.735
更新日期:2007-08-01 00:00:00
abstract::The purpose of this prospective study was to verify and compare the strengths of various blood markers and fibrosis models in predicting significant liver fibrosis. One hundred fifty-eight patients with chronic liver disease who underwent liver biopsy were enrolled. The mean age was 41 yr and male patients accounted f...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2010.25.1.67
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Invasive Streptococcus agalactiae (group B streptococcus, GBS) infection most commonly occurs in infants; however, cases of GBS infection in adults, particularly in the elderly with significant underlying diseases, are being increasingly reported. We analyzed the serotype specific opsonophagocytic antibodies...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2018.33.e127
更新日期:2018-04-16 00:00:00