Variants of windmill nystagmus.


:Windmill nystagmus is characterized by a clock-like rotation of the beating direction of a jerk nystagmus suggesting separate horizontal and vertical oscillators, usually 90° out of phase. We report oculographic characteristics in three patients with variants of windmill nystagmus in whom the common denominator was profound visual loss due to retinal diseases. Two patients showed a clock-like pattern, while in the third, the nystagmus was largely diagonal (in phase or 180° out of phase) but also periodically changed direction by 180°. We hypothesize that windmill nystagmus is a unique manifestation of "eye movements of the blind." It emerges when the central structures, including the cerebellum, that normally keep eye movements calibrated and gaze steady can no longer perform their task, because they are deprived of the retinal image motion that signals a need for adaptive recalibration.


J Neurol


Journal of neurology


Choi KD,Shin HK,Kim JS,Kim SH,Choi JH,Kim HJ,Zee DS




Has Abstract


2016-07-01 00:00:00














  • Correction to: Diagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo‑ocular reflex: when nothing else matters.

    abstract::The article Diagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo‑ocular reflex: when nothing else matters, written by Florin Gandor, Manfred Tesch, Hannelore Neuhauser, Doreen Gruber, Hans‑Jochen Heinze, Georg Ebersbach and Thomas Lempert, was originally published electr...

    journal_title:Journal of neurology

    pub_type: 杂志文章,已发布勘误


    authors: Gandor F,Tesch M,Neuhauser H,Gruber D,Heinze HJ,Ebersbach G,Lempert T

    更新日期:2020-10-01 00:00:00

  • Pain and autonomic dysfunction in patients with sarcoidosis and small fibre neuropathy.

    abstract::Small fibre neuropathy (SFN) has been demonstrated in sarcoidosis. However, a systematic analysis of neuropathic pain and autonomic symptoms, key features of SFN, has not been performed. Clinimetric evaluation of pain and autonomic symptoms using the neuropathic pain scale (NPS) and the modified Composite Autonomic Sy...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Bakkers M,Faber CG,Drent M,Hermans MC,van Nes SI,Lauria G,De Baets M,Merkies IS

    更新日期:2010-12-01 00:00:00

  • Neuroprotection with glatiramer acetate: evidence from the PreCISe trial.

    abstract::The phase III, multicenter, randomized, placebo-controlled PreCISe trial assessed glatiramer acetate (GA) effects in patients with clinically isolated syndromes (CIS) suggestive of multiple sclerosis (MS). To assess the neuroprotective effect of GA in a subset of patients in the PreCISe trial, we used proton magnetic ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Arnold DL,Narayanan S,Antel S

    更新日期:2013-07-01 00:00:00

  • SOD2 as a potential modifier of X-linked adrenoleukodystrophy clinical phenotypes.

    abstract::X-linked adrenoleukodystrophy (XALD), a neurological disorder caused by mutations in the peroxisomal membrane protein gene ABCD1, presents as a rapidly progressing, inflammatory cerebral demyelination (cerebral cases) or a slowly progressing, distal axonopathy (non-cerebral cases). Specific ABCD1 defects do not explai...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Brose RD,Avramopoulos D,Smith KD

    更新日期:2012-07-01 00:00:00

  • PTPRC (CD45) C77G mutation does not contribute to multiple sclerosis susceptibility in Sardinian patients.

    abstract::A linkage and association of the CD45 (protein-tyrosine phosphatase, receptor-type C) C77G polymorphism and multiple sclerosis (MS) has been found in some studies but not in others. We analysed the C77G polymorphism in MS patients from the genetically homogeneous population of Sardinia. Using the transmission disequil...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Cocco E,Murru MR,Melis C,Schirru L,Solla E,Lai M,Rolesu M,Marrosu MG

    更新日期:2004-09-01 00:00:00

  • Schwartz-Jampel syndrome associated with von Willebrand's disease.

    abstract::We report a very rare case of Schwartz-Jampel syndrome associated with von Willebrand's disease. This association might be coincidental because of the different modes of inheritance of the two disorders. However, we speculate that there might be some link between the two disorders, for example in the locus of the affe...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Kuriyama M,Shinmyozu K,Osame M,Kawahira M,Igata A

    更新日期:1985-01-01 00:00:00

  • Amyotrophic lateral sclerosis: early predictors of prolonged survival.

    abstract:OBJECTIVE:In order to define the predictors of prolonged survival available at the time of first examination we performed a historical cohort study of amyotrophis sclerosis (ALS) patients referred to our ALS Clinic over the last 20 years. METHODS:In a group of 1034 patients with the diagnosis of definite or probable A...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Czaplinski A,Yen AA,Appel SH

    更新日期:2006-11-01 00:00:00

  • Evolution of dose and response to botulinum toxin A in cervical dystonia: a multicenter study.

    abstract::Botulinum neurotoxin (BoNT) is an effective treatment for cervical dystonia (CD). Long-term changes of several variables, including the dose of BoNT, in these patients is largely unknown. We reviewed the clinical charts of 275 patients with CD treated with BoNT type A (BoNT-A) for at least 5 years since 1989 at ten te...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究


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    更新日期:2011-06-01 00:00:00

  • Cluster headache: pathophysiology, diagnosis and treatment.

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    journal_title:Journal of neurology

    pub_type: 杂志文章,评审


    authors: Ljubisavljevic S,Zidverc Trajkovic J

    更新日期:2019-05-01 00:00:00

  • Population studies highlight an increased risk of dementia in both dependent and non-dependent drinkers.

    abstract:: ...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Hu M,Corkill R

    更新日期:2019-03-01 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Uphaus T,Oberwittler C,Groppa S,Zipp F,Bittner S

    更新日期:2017-12-01 00:00:00

  • Rimmed vacuolar distal myopathy. An ultrastructural study.

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Mizusawa H,Kurisaki H,Takatsu M,Inoue K,Mannen T,Toyokura Y,Nakanishi T

    更新日期:1987-04-01 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Martin DT,Swash M

    更新日期:1987-12-01 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章,评审


    authors: Liu H,Wang J,Xu Z

    更新日期:2020-11-01 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Sehle A,Vieten M,Sailer S,Mündermann A,Dettmers C

    更新日期:2014-09-01 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Schröder R,Keller E,Flacke S,Schmidt S,Pohl C,Klockgether T,Schlegel U

    更新日期:1999-11-01 00:00:00

  • Tissue damage within normal appearing white matter in early multiple sclerosis: assessment by the ratio of T1- and T2-weighted MR image intensity.

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Beer A,Biberacher V,Schmidt P,Righart R,Buck D,Berthele A,Kirschke J,Zimmer C,Hemmer B,Mühlau M

    更新日期:2016-08-01 00:00:00

  • Intrafamilial phenotype variation in Friedreich's disease: possible exceptions to diagnostic criteria.

    abstract::Three families are described which include members with "typical" Friedreich's disease (FD) and others who are ataxic but do not satisfy all the diagnostic criteria for that disease. In family A two patients have an early-onset, rapidly progressive FD, while two others have a late-onset, more benign form. In families ...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Filla A,De Michele G,Cavalcanti F,Santorelli F,Santoro L,Campanella G

    更新日期:1991-06-01 00:00:00

  • Specific B- and T-cell populations are associated with cognition in patients with epilepsy and antibody positive and negative suspected limbic encephalitis.

    abstract:OBJECTIVE:Neuropsychological impairments are major symptoms of autoimmune limbic encephalitis (LE) epilepsy patients. In LE epilepsy patients with an autoimmune response against intracellular antigens as well as in antibody-negative patients, the antibody findings and magnetic resonance imaging pathology correspond poo...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Helmstaedter C,Hansen N,Leelaarporn P,Schwing K,Oender D,Widman G,Racz A,Surges R,Becker A,Witt JA

    更新日期:2020-08-20 00:00:00

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    pub_type: 杂志文章,多中心研究


    authors: Balloy G,Pelletier J,Suchet L,Lebrun C,Cohen M,Vermersch P,Zephir H,Duhin E,Gout O,Deschamps R,Le Page E,Edan G,Labauge P,Carra-Dallieres C,Rumbach L,Berger E,Lejeune P,Devos P,N'Kendjuo JB,Coustans M,Auffray-Calv

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  • What is pathological with gaze shift fragmentation in Parkinson's disease?

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Kimmig H,Haussmann K,Mergner T,Lücking CH

    更新日期:2002-06-01 00:00:00

  • Bilateral reductions of hippocampal volume, glucose metabolism, and wada hemispheric memory performance are related to the duration of mesial temporal lobe epilepsy.

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Jokeit H,Ebner A,Arnold S,Schüller M,Antke C,Huang Y,Steinmetz H,Seitz RJ,Witte OW

    更新日期:1999-10-01 00:00:00

  • Epidemics and outbreaks of peripheral nervous system disorders: II. Toxic and nutritional causes.

    abstract::Peripheral neuropathies have various causes, both infectious and non-infectious. When we think of "epidemics", we often refer to an infectious or even post-infectious origin. Nevertheless, the history of mankind is marked by episodes of epidemics of peripheral neuropathies of non-infectious nature, either of nutrition...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Mathis S,Soulages A,Vallat JM,Le Masson G

    更新日期:2020-09-11 00:00:00

  • 18F-FDG PET in neurodegenerative Langerhans cell histiocytosis : results and potential interest for an early diagnosis of the disease.

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Ribeiro MJ,Idbaih A,Thomas C,Remy P,Martin-Duverneuil N,Samson Y,Donadieu J,Hoang-Xuan K

    更新日期:2008-04-01 00:00:00

  • Botulism: clinical neurophysical findings.

    abstract::Four cases of mild botulinus type B intoxication are reported with the clinical neurophysiological studies. Electromyographically tetanic stimulation of the N. ulnaris initially led to tetanic potentiation of the muscle action potential. After an interval without any symptoms tetanic reduction became apparent between ...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Hagenah R,Müller-Jensen A

    更新日期:1978-02-14 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章,评审


    authors: Ferrazzano G,Crisafulli SG,Baione V,Tartaglia M,Cortese A,Frontoni M,Altieri M,Pauri F,Millefiorini E,Conte A

    更新日期:2020-06-05 00:00:00

  • Platelet-derived extracellular vesicles in Huntington's disease.

    abstract::The production and release of extracellular vesicles (EV) is a property shared by all eukaryotic cells and a phenomenon frequently exacerbated in pathological conditions. The protein cargo of EV, their cell type signature and availability in bodily fluids make them particularly appealing as biomarkers. We recently dem...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Denis HL,Lamontagne-Proulx J,St-Amour I,Mason SL,Weiss A,Chouinard S,Barker RA,Boilard E,Cicchetti F

    更新日期:2018-11-01 00:00:00

  • The role of mutations in COL6A3 in isolated dystonia.

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Lohmann K,Schlicht F,Svetel M,Hinrichs F,Zittel S,Graf J,Lohnau T,Schmidt A,Mir P,Krause P,Lang AE,Jabusch HC,Wolters A,Kamm C,Zeuner KE,Altenmüller E,Naz S,Chung SJ,Kostic VS,Münchau A,Kühn AA,Brüggemann N,Kl

    更新日期:2016-04-01 00:00:00

  • Coenzyme Q in serum and muscle of 5 patients with Kearns-Sayre syndrome and 12 patients with ophthalmoplegia plus.

    abstract::Coenzyme Q10 (CoQ) was measured in serum and muscle of 17 patients with ophthalmoplegia plus (including 5 patients with Kearns-Sayre syndrome), in muscle of 9 patients with neurogenic atrophies, 5 patients with myositis, and 5 patients with progressive muscular dystrophies (including 1 patient with oculopharyngeal dys...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Zierz S,Jahns G,Jerusalem F

    更新日期:1989-02-01 00:00:00

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    abstract::The association of pathology and neurological deficit with quality of life (QoL) in multiple sclerosis (MS) is not fully understood. In this study, magnetic resonance imaging (MRI) measures of pathology--T1 and T2 lesion volume and ratio; active T2 lesion number; global and regional brain volume and atrophy; magnetiza...

    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Hayton T,Furby J,Smith KJ,Altmann DR,Brenner R,Chataway J,Hunter K,Tozer DJ,Miller DH,Kapoor R

    更新日期:2012-02-01 00:00:00