Cost-Effectiveness of Cardiovascular Screening in Patients With Rheumatoid Arthritis.

Abstract:

OBJECTIVE:Early detection and preemptive treatment of patients at risk is of great importance in reducing the excess risk of cardiovascular (CV) disease in rheumatoid arthritis (RA). However, it is unclear how much screening is cost-effective in RA. The objective is to assess whether CV screening in RA proves to be cost-effective from a medical perspective, using different scenarios based on different guidelines. METHODS:A Markov chain model was used with a time horizon of 10 years. Parameter values were mainly obtained from literature and from RA patients screened for CV diseases at the Radboud University Medical Centre, Nijmegen, The Netherlands. The primary outcome was incremental cost-effectiveness expressed as costs per quality-adjusted life year (QALY) gained. Probabilistic sensitivity analysis was performed and described in willingness-to-pay curves; several scenarios were built. RESULTS:In the base case scenario, in 82% of the simulations, screening proved to be dominant compared to no screening. The mean QALY gain was 0.09 (95% percentile -0.07, 0.27), and the mean cost savings were €-1,057 (95% percentile -€2,825, €333). Different scenarios showed small differences in cost-effectiveness; the probability that screening is dominant remained high with the lowest probability being 50% for a very conservative scenario. CONCLUSION:Screening for CV events in RA patients was estimated to be cost-effective with high chances of being less expensive and more effective. These results support endorsement of screening for CV risk in patients with RA.

authors

Kievit W,Maurits JS,Arts EE,van Riel PL,Fransen J,Popa CD

doi

10.1002/acr.22929

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

175-182

issue

2

eissn

2151-464X

issn

2151-4658

journal_volume

69

pub_type

杂志文章
  • Modifications in Systemic Rheumatic Disease Medications: Patients' Perspectives during the Height of the COVID-19 Pandemic in New York City.

    abstract:OBJECTIVE:Concerns about SARS-CoV-2 infection may have led to changes or discontinuation of immunosuppressive medications among patients with systemic rheumatic disease. Our goal was to assess patients' perspectives regarding medication modifications and deviations from planned uses during the height of the pandemic. ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24489

    authors: Mancuso CA,Duculan R,Jannat-Khah D,Barbhaiya M,Bass AR,Mandl LA,Mehta B

    更新日期:2020-10-21 00:00:00

  • Altered multi-segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers-Danlos Syndrome/Hypermobility spectrum disorder. A case-control study.

    abstract:OBJECTIVE:Ankle-foot problems have a considerable impact on daily functioning in patients with hypermobile Ehlers-Danlos syndrome and Hypermobility Spectrum Disorder (hEDS/HSD). Therefore, the objective of this study is to identify alterations in multi-segment ankle and foot kinematics during gait and assessing foot fu...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24526

    authors: Vermeulen S,De Mits S,De Ridder R,Calders P,De Schepper J,Malfait F,Rombaut L

    更新日期:2020-12-04 00:00:00

  • Increased risk of subarachnoid hemorrhage in patients with systemic lupus erythematosus: a nationwide population-based study.

    abstract:OBJECTIVE:A relatively common occurrence of spontaneous subarachnoid hemorrhage (SAH) in patients with systemic lupus erythematosus (SLE) has been noted; however, the subsequent studies were conflicting. This nationwide population-based study aimed to evaluate the risk of SAH in patients with SLE. METHODS:We identifie...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.21846

    authors: Chang YS,Liu CJ,Chen WS,Lai CC,Wang SH,Chen TJ,Tzeng CH,Tsai CY,Wang SJ

    更新日期:2013-04-01 00:00:00

  • Musculoskeletal pain and incident disability in community-dwelling older adults.

    abstract:OBJECTIVE:To test the hypothesis that the number of areas of musculoskeletal pain reported is related to incident disability. METHODS:Subjects included 898 older persons from the Rush Memory and Aging Project without dementia, stroke, or Parkinson's disease at baseline. All participants underwent detailed baseline eva...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20200

    authors: Buchman AS,Shah RC,Leurgans SE,Boyle PA,Wilson RS,Bennett DA

    更新日期:2010-09-01 00:00:00

  • Very early improvements in the wrist and hand assessed by power Doppler sonography predicting later favorable responses in tocilizumab-treated patients with rheumatoid arthritis.

    abstract:OBJECTIVE:To investigate the response of tocilizumab (TCZ) in patients with rheumatoid arthritis (RA) by ultrasonographic evaluation of changes in the wrist and hand, and to determine whether such assessments during early TCZ treatment predict later clinical outcome. METHODS:Thirty-two RA patients about to receive TCZ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20537

    authors: Kume K,Amano K,Yamada S,Hatta K,Kuwaba N,Ohta H

    更新日期:2011-10-01 00:00:00

  • Diagnostic accuracy, internal consistency, and convergent validity of the Greek version of the patient health questionnaire 9 in diagnosing depression in rheumatologic disorders.

    abstract:OBJECTIVE:The Patient Health Questionnaire 9 (PHQ-9) was developed to screen for depressive disorders in community, primary care, and medical settings. We aimed to estimate its diagnostic accuracy, internal consistency, reliability, and convergent validity in diagnosing major depressive disorder (MDD) in Greek patients...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20505

    authors: Hyphantis T,Kotsis K,Voulgari PV,Tsifetaki N,Creed F,Drosos AA

    更新日期:2011-09-01 00:00:00

  • Treating to a target in established active rheumatoid arthritis patients receiving a tumor necrosis factor inhibitor: results from a real-world cluster-randomized adalimumab trial.

    abstract:OBJECTIVE:In early rheumatoid arthritis (RA), treating to a target is more effective than routine care (RC). Our aim was to determine if treating to a target has better outcomes than RC in established active RA. METHODS:We used a real-world, 18-month cluster-randomized trial in established active RA patients treated w...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/acr.22010

    authors: Pope JE,Haraoui B,Rampakakis E,Psaradellis E,Thorne C,Sampalis JS,Optimization of Adalimumab Trial Investigators.

    更新日期:2013-09-01 00:00:00

  • Self-management strategies in overweight and obese Canadians with arthritis.

    abstract:OBJECTIVE:To estimate the prevalence of overweight and obese Canadians with arthritis and to describe their use of arthritis self-management strategies, as well as explore the factors associated with not engaging in any self-management strategies. METHODS:Respondents to the 2009 Survey on Living with Chronic Diseases ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20654

    authors: Bernatsky S,Rusu C,O'Donnell S,Mackay C,Hawker G,Canizares M,Badley E

    更新日期:2012-02-01 00:00:00

  • Clinical Profiles of Young Adults With Juvenile-Onset Fibromyalgia With and Without a History of Trauma.

    abstract:OBJECTIVE:To examine the differential presentation(s) of psychological and health-related outcomes in young adults with juvenile-onset fibromyalgia (FM) with and without a history of trauma, compared to healthy controls. METHODS:In total, 110 participants (86 with juvenile-onset FM and 24 healthy controls, with a mean...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23192

    authors: Nelson S,Cunningham N,Peugh J,Jagpal A,Arnold LM,Lynch-Jordan A,Kashikar-Zuck S

    更新日期:2017-11-01 00:00:00

  • Predicting Incident Radiographic Knee Osteoarthritis in Middle-Aged Women Within Four Years: The Importance of Knee-Level Prognostic Factors.

    abstract:OBJECTIVE:To develop and internally validate risk models and a clinical risk score tool to predict incident radiographic knee osteoarthritis (RKOA) in middle-aged women. METHODS:We analyzed 649 women in the Chingford 1,000 Women study. The outcome was incident RKOA, defined as Kellgren/Lawrence grade 0-1 at baseline a...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23932

    authors: Garriga C,Sánchez-Santos MT,Judge A,Hart D,Spector T,Cooper C,Arden NK

    更新日期:2020-01-01 00:00:00

  • Perspectives of vulnerable U.S Hispanics with rheumatoid arthritis on depression: awareness, barriers to disclosure, and treatment options.

    abstract:OBJECTIVE:Despite the high prevalence of depression among vulnerable Hispanics with rheumatoid arthritis (RA), many do not disclose it or seek treatment. This study explored patient perceptions of depression, its association with their primary disease, barriers to disclosure, reasons for low utilization of mental healt...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22462

    authors: Withers M,Moran R,Nicassio P,Weisman MH,Karpouzas GA

    更新日期:2015-04-01 00:00:00

  • Preeclampsia Risk Prediction Model for Chinese Pregnant Patients With Systemic Lupus Erythematosus.

    abstract:OBJECTIVE:To screen for a high risk of preeclampsia in women with systemic lupus erythematosus (SLE). METHODS:A total of 513 antenatal care records of pregnant patients with SLE were obtained, and the data were randomly assigned to either a development set (n = 342) or a validation set (n = 171). Preeclampsia predicto...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24265

    authors: Jiang M,Wang Y,Fu Q,Lin S,Wu J,Di W

    更新日期:2020-11-01 00:00:00

  • Efficiency Gains for Rheumatology Consultation Using a Novel Electronic Referral System in a Safety-Net Health Setting.

    abstract:OBJECTIVE:Health information technology (HIT) holds promise in increasing access to rheumatologists by improving the quality and efficiency of referrals, but few studies have examined its use for this purpose. We evaluated the use and impact of a novel electronic referral (eReferral) system in rheumatology in a safety-...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22559

    authors: Scheibe MM,Imboden JB,Schmajuk G,Margaretten M,Graf JD,Chen AH,Yelin EH,Yazdany J

    更新日期:2015-08-01 00:00:00

  • Traditional cardiovascular risk factors and coronary artery calcification in adults with polymyositis and dermatomyositis: a Danish multicenter study.

    abstract:OBJECTIVE:To determine the occurrence of traditional cardiovascular (CV) risk factors and coronary artery calcification (CAC) in adults with polymyositis (PM) or dermatomyositis (DM) compared to healthy controls and to assess the association between CV risk factors, PM/DM, and CAC score. METHODS:Traditional CV risk fa...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.22520

    authors: Diederichsen LP,Diederichsen AC,Simonsen JA,Junker P,Søndergaard K,Lundberg IE,Tvede N,Gerke O,Christensen AF,Dreyer L,Petersen H,Ejstrup L,Kay SD,Jacobsen S

    更新日期:2015-05-01 00:00:00

  • The temporal relationship between juvenile idiopathic arthritis disease activity and uveitis activity.

    abstract:OBJECTIVE:To determine whether there is a temporal association between arthritis and uveitis activity among children with juvenile idiopathic arthritis-associated uveitis (JIA-U). METHODS:Uveitis and arthritis data from JIA-U patients ≤21 years were collected from 7/2013-12/2019 at a tertiary care center. Arthritis ac...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24483

    authors: Liebling EJ,Faig W,Chang JC,Mendoza E,Moore N,Ledesma Vicioso N,Lerman MA

    更新日期:2020-10-12 00:00:00

  • Prevalence and incidence in patients with autoimmune rheumatic diseases: a nationwide population-based study in Taiwan.

    abstract:OBJECTIVE:The purpose of this study was to determine the prevalence, incidence, and mortality rates of autoimmune rheumatic diseases (ARDs) by using a population-based database. METHODS:We used the longitudinal health insurance database (comprising 1,000,000 beneficiaries) of the Taiwan National Health Insurance from ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.21820

    authors: Yu KH,See LC,Kuo CF,Chou IJ,Chou MJ

    更新日期:2013-02-01 00:00:00

  • Efficacy of cardiorespiratory aerobic exercise in rheumatoid arthritis: meta-analysis of randomized controlled trials.

    abstract:OBJECTIVE:Several lines of evidence have emphasized an improvement in aerobic capacity and muscle strength after physical exercise programs in rheumatoid arthritis (RA) patients. Our objective was to evaluate the efficacy of aerobic exercises in RA on quality of life, function, and clinical and radiologic outcomes by a...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/acr.20146

    authors: Baillet A,Zeboulon N,Gossec L,Combescure C,Bodin LA,Juvin R,Dougados M,Gaudin P

    更新日期:2010-07-01 00:00:00

  • Comparison of three methods for calculating the Bath Ankylosing Spondylitis Metrology Index in a randomized placebo-controlled study.

    abstract:OBJECTIVE:To compare 3 methods for calculating the Bath Ankylosing Spondylitis Metrology Index (BASMI) score using patients who participated in the GO-RAISE study. METHODS:Patients with active ankylosing spondylitis (AS) were randomly assigned in a 1:1.8:1.8 ratio to receive subcutaneous injections of placebo, golimum...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/acr.21771

    authors: van der Heijde D,Deodhar A,Inman RD,Braun J,Hsu B,Mack M

    更新日期:2012-12-01 00:00:00

  • Potential impact on patient residence to hospital travel distance and access to care under a policy of preferential referral to high-volume knee replacement hospitals.

    abstract:OBJECTIVE:To examine the potential impact of a policy of selective referral to high-volume knee replacement hospitals on patients' travel distance to hospitals and access to care for patients seeking total knee replacement (TKR) in urban and rural settings. METHODS:The travel distance required for patients to reach th...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.21611

    authors: FitzGerald JD,Soohoo NF,Losina E,Katz JN

    更新日期:2012-06-01 00:00:00

  • Efficacy of Mycophenolate Mofetil and Oral Cyclophosphamide on Skin Thickness: Post Hoc Analyses From Two Randomized Placebo-Controlled Trials.

    abstract:OBJECTIVE:To assess the efficacy of mycophenolate mofetil (MMF) and cyclophosphamide (CYC) on modified Rodnan skin score (MRSS) in participants enrolled in the Scleroderma Lung Study (SLS) I and II. METHODS:SLS I participants received daily oral CYC or matching placebo for 1 year, whereas SLS II participants received ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/acr.23282

    authors: Namas R,Tashkin DP,Furst DE,Wilhalme H,Tseng CH,Roth MD,Kafaja S,Volkmann E,Clements PJ,Khanna D,Participants in the Scleroderma Lung Study I and members of the Scleroderma Lung Study II Research Group.

    更新日期:2018-03-01 00:00:00

  • External Validation of the Lupus Impact Tracker in a Southeastern US Longitudinal Cohort With Systemic Lupus Erythematosus.

    abstract:OBJECTIVE:To examine the external validity of the Lupus Impact Tracker (LIT), a systemic lupus erythematosus (SLE)-specific, health-related quality of life (HRQoL) tool in a population-based cohort of patients with SLE in Atlanta, Georgia. We modeled the association of LIT scores with patient-reported measures of SLE a...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23009

    authors: Brandt JE,Drenkard C,Kan H,Bao G,Dunlop-Thomas C,Pobiner B,Chang DJ,Jolly M,Lim SS

    更新日期:2017-06-01 00:00:00

  • Early Magnetic Resonance Imaging-Based Changes in Patients With Meniscal Tear and Osteoarthritis: Eighteen-Month Data From a Randomized Controlled Trial of Arthroscopic Partial Meniscectomy Versus Physical Therapy.

    abstract:OBJECTIVE:The present study was undertaken to evaluate changes in knee magnetic resonance imaging (MRI) findings over the course of 18 months in subjects with osteoarthritic change and meniscal tear treated with arthroscopic partial meniscectomy (APM) or nonoperatively with physical therapy (PT). METHODS:We used 18-mo...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/acr.23891

    authors: Collins JE,Losina E,Marx RG,Guermazi A,Jarraya M,Jones MH,Levy BA,Mandl LA,Martin SD,Wright RW,Spindler KP,Katz JN,MeTeOR Investigator Group.

    更新日期:2020-05-01 00:00:00

  • Recommendation Rates for Physical Therapy, Lifestyle Counseling, and Pain Medications for Managing Knee Osteoarthritis in Ambulatory Care Settings: A Cross-Sectional Analysis of the National Ambulatory Care Survey (2007-2015).

    abstract:OBJECTIVE:To describe and compare triennial rates of physicians' recommendations for physical therapy (PT), lifestyle counseling, and pain medication for knee osteoarthritis (OA) and to identify patient, physician, and practice factors associated with each treatment recommendation. METHODS:We conducted a cross-section...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24064

    authors: Khoja SS,Almeida GJ,Freburger JK

    更新日期:2020-02-01 00:00:00

  • In vivo Compositional Changes in the Articular Cartilage of the Patellofemoral Joint following Anterior Cruciate Ligament Reconstruction.

    abstract:OBJECTIVE:To compare T1ρ relaxation times of the medial and lateral regions of the patella and femoral trochlea at 6 and 12 months post-anterior cruciate ligament reconstruction (ACLR) on the ACLR and contralateral limb. Greater T1ρ relaxation times are associated with a lesser proteoglycan density of articular cartila...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24561

    authors: Boling MC,Dupell M,Pfeiffer SJ,Wallace K,Lalush D,Spang JT,Nissman D,Pietrosimone B

    更新日期:2021-01-18 00:00:00

  • Impact of Uveitis on Quality of Life in Adult Patients With Juvenile Idiopathic Arthritis.

    abstract:OBJECTIVE:To establish the impact of uveitis on the quality of life (QoL) in adult patients with juvenile idiopathic arthritis (JIA). METHODS:Adult patients with a history of JIA, both with (n = 31) or without (n = 51) chronic anterior uveitis, were included. Their scores on 3 validated QoL questionnaires (National Ey...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23224

    authors: Haasnoot AJW,Sint Jago NFM,Tekstra J,de Boer JH

    更新日期:2017-12-01 00:00:00

  • Cutaneous ulceration in dermatomyositis: association with anti-melanoma differentiation-associated gene 5 antibodies and interstitial lung disease.

    abstract:OBJECTIVE:To identify clinical and serologic correlates of cutaneous ulcers in dermatomyositis (DM). METHODS:We retrospectively examined a cohort of 152 DM patients. We compared the features of patients with ulcers to those without ulcers using chi-square or Fisher's exact tests and used univariate and multivariate lo...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22498

    authors: Narang NS,Casciola-Rosen L,Li S,Chung L,Fiorentino DF

    更新日期:2015-05-01 00:00:00

  • Association of higher methotrexate dose with lymphoproliferative disease onset in rheumatoid arthritis patients.

    abstract:OBJECTIVE:Methotrexate (MTX) is used as an anchor drug for rheumatoid arthritis (RA). Lymphoproliferative disease (LPD) occasionally develops in patients treated with MTX, and is known as MTX-associated LPD (MTX-LPD). Although MTX-LPD occurs mainly in RA patients, it has not been established if MTX administration is an...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22306

    authors: Kameda T,Dobashi H,Miyatake N,Inoo M,Onishi I,Kurata N,Mitsunaka H,Kawakami K,Fukumoto T,Susaki K,Izumikawa M,Nakashima S,Shimada H,Takeuchi Y,Haba R,Mano S,Onishi H,Imataki O,Matsunaga T

    更新日期:2014-09-01 00:00:00

  • Development and validation of a magnetic resonance imaging reference criterion for defining a positive sacroiliac joint magnetic resonance imaging finding in spondyloarthritis.

    abstract:OBJECTIVE:To validate a magnetic resonance imaging (MRI) reference criterion for a positive sacroiliac (SI) joint MRI finding based on the level of confidence in the classification of spondyloarthritis (SpA) by expert MRI readers. METHODS:Four readers assessed SI joint MRIs in 2 inception cohorts (cohorts A and B) of ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.21893

    authors: Weber U,Zubler V,Pedersen SJ,Rufibach K,Lambert RG,Chan SM,Østergaard M,Maksymowych WP

    更新日期:2013-06-01 00:00:00

  • A 21-Year-Old Woman with Joint Pain and Skin Ulceration.

    abstract::The illness started with pain and stiffness in her bilateral hands and wrists four months prior, with progression to bilateral elbows, knees, and ankles. The pain and stiffness were worse in the morning and limited her ability to use her hands or walk comfortably. She also noted swelling of her hands, knees, and ankle...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24141

    authors: French S,Lang U,Margaretten M

    更新日期:2020-01-21 00:00:00

  • Association between physical exercise, body mass index, and risk of fibromyalgia: longitudinal data from the Norwegian Nord-Trøndelag Health Study.

    abstract:OBJECTIVE:To examine the association between leisure time physical exercise, body mass index (BMI), and risk of fibromyalgia (FM). METHODS:A longitudinal study with baseline assessment of physical exercise (frequency, duration, and intensity) and BMI was used to explore the risk of having FM at 11-year followup in a l...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20118

    authors: Mork PJ,Vasseljen O,Nilsen TI

    更新日期:2010-05-01 00:00:00