Altered multi-segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers-Danlos Syndrome/Hypermobility spectrum disorder. A case-control study.

Abstract:

OBJECTIVE:Ankle-foot problems have a considerable impact on daily functioning in patients with hypermobile Ehlers-Danlos syndrome and Hypermobility Spectrum Disorder (hEDS/HSD). Therefore, the objective of this study is to identify alterations in multi-segment ankle and foot kinematics during gait and assessing foot function and pain in these patients. METHODS:Twenty-three women with hEDS/HSD and 23 healthy controls participated in this three-dimensional (3D) gait analysis. Multi-segment ankle and foot kinematics were collected using the Ghent Foot Model (GFM) and analyzed with Statistical Parametric Mapping (SPM). Foot function and pain were assessed using Visual Analogue Scale (VAS)-scores, the Margolis Pain Diagram, and the Foot Function Index (FFI). RESULTS:Levels of pain and foot dysfunction were significantly higher in subjects with hEDS/HSD (p<0.001). Kinematic curve analyses provide evidence for a hypermobile first ray, represented by a significantly increased eversion position of the medial forefoot during stance phase (p<0.001) in subjects with hEDS/HSD compared to controls. In addition, significantly more dorsiflexion was found in the medial and lateral forefoot and the rearfoot (p<0.001). At the midfoot an increased plantar flexion (p<0.001) and at the level of the hallux a decreased dorsiflexion (p=0.037) and increased inversion (p<0.001) and abduction (p=0.016) were found in subjects with hEDS/HSD. CONCLUSION:This study is the first to apply a multi-segment foot model during gait in hEDS/HSD, which confirms the characteristic hypermobility throughout the foot, especially the hypermobile first ray.

authors

Vermeulen S,De Mits S,De Ridder R,Calders P,De Schepper J,Malfait F,Rombaut L

doi

10.1002/acr.24526

subject

Has Abstract

pub_date

2020-12-04 00:00:00

eissn

2151-464X

issn

2151-4658

pub_type

杂志文章
  • Milk consumption and progression of medial tibiofemoral knee osteoarthritis: data from the Osteoarthritis Initiative.

    abstract:OBJECTIVE:Milk consumption has long been recognized for its important role in bone health, but its role in the progression of knee osteoarthritis (OA) is unclear. We examined the prospective association of milk consumption with radiographic progression of knee OA. METHODS:In the Osteoarthritis Initiative, 2,148 partic...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22297

    authors: Lu B,Driban JB,Duryea J,McAlindon T,Lapane KL,Eaton CB

    更新日期:2014-06-01 00:00:00

  • Association Between Declining Walking Speed and Increasing Bone Marrow Lesion and Effusion Volume in Individuals with Accelerated Knee Osteoarthritis.

    abstract:OBJECTIVE:To determine whether a decline in walking speed during the year prior to disease onset is associated with concurrent changes in cartilage, bone marrow lesions (BMLs), or effusion in adults who develop common knee osteoarthritis (OA), accelerated knee OA, or no knee OA. METHODS:We identified 3 groups from the...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23613

    authors: Harkey MS,Price LL,McAlindon TE,Davis JE,Stout AC,Lu B,Zhang M,Eaton CB,Barbe MF,Lo GH,Driban JB

    更新日期:2019-02-01 00:00:00

  • Functional impairments characterizing mild, moderate, and severe hallux valgus.

    abstract:OBJECTIVE:Hallux valgus (HV) has been linked to functional disability and increased risk of falls, but mechanisms underpinning functional disability are unclear. This study investigated functional performance, muscle strength, and plantar pressures in adults with mild, moderate, and severe HV compared to controls, whil...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22380

    authors: Hurn SE,Vicenzino B,Smith MD

    更新日期:2015-01-01 00:00:00

  • Exercise programs in trials for patients with ankylosing spondylitis: do they really have the potential for effectiveness?

    abstract:OBJECTIVE:To evaluate if exercise programs in trials for patients with ankylosing spondylitis (AS) have the potential for effectiveness. METHODS:A systematic literature search was performed and randomized trials examining the effectiveness of exercise programs for AS patients were analyzed according to 3 elements: whe...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20415

    authors: Dagfinrud H,Halvorsen S,Vøllestad NK,Niedermann K,Kvien TK,Hagen KB

    更新日期:2011-04-01 00:00:00

  • Practice Pattern of Hepatitis B Testing in Rheumatoid Arthritis Patients: A Cross-National Comparison Between the US and Taiwan.

    abstract:OBJECTIVE:The hepatitis B virus (HBV) testing rates and patterns in rheumatoid arthritis (RA) patients starting disease-modifying antirheumatic drugs (DMARDs) have not been well studied. We describe and compare the practice patterns of HBV testing among RA patients in the US and Taiwan. METHODS:We conducted a retrospe...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.23241

    authors: Lin TC,Hashemi N,Kim SC,Yang YK,Yoshida K,Tedeschi S,Desai R,Solomon DH

    更新日期:2018-01-01 00:00:00

  • Clinical tool to identify patients who are most likely to achieve long-term improvement in physical function after total hip arthroplasty.

    abstract:OBJECTIVE:To develop a clinical risk prediction tool to identify patients most likely to experience long-term clinically meaningful functional improvement following total hip arthroplasty (THA). METHODS:We studied 282 patients from 2 health districts in England (Portsmouth and North Staffordshire) who were ≥45 years o...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.21594

    authors: Judge A,Javaid MK,Arden NK,Cushnaghan J,Reading I,Croft P,Dieppe PA,Cooper C

    更新日期:2012-06-01 00:00:00

  • Ultrasound of the knee during voluntary quadriceps contraction: a technique for detecting otherwise occult effusions.

    abstract:OBJECTIVE:To describe 1) a technique that can detect synovial effusions not seen on static ultrasound (US) examination and 2) the characteristics of patients with knee osteoarthritis (OA) for whom this technique proved useful. METHODS:From reviewed records of 76 patients with knee OA (112 knees) that we had seen for U...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.20047

    authors: Ike RW,Somers EC,Arnold EL,Arnold WJ

    更新日期:2010-05-01 00:00:00

  • Enhanced Pain Sensitivity Among Individuals With Symptomatic Knee Osteoarthritis: Potential Sex Differences in Central Sensitization.

    abstract:OBJECTIVE:Symptomatic knee osteoarthritis (OA) is a condition commonly associated with increased pain, disability, and functional limitations. Given the poor correspondence between radiographic evidence and clinical pain, central sensitization has been implicated as a potential mechanism underlying pain facilitation in...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22712

    authors: Bartley EJ,King CD,Sibille KT,Cruz-Almeida Y,Riley JL 3rd,Glover TL,Goodin BR,Sotolongo AS,Herbert MS,Bulls HW,Staud R,Fessler BJ,Redden DT,Bradley LA,Fillingim RB

    更新日期:2016-04-01 00:00:00

  • Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and hyperuricemia: a Cross-sectional Study.

    abstract:OBJECTIVE:Although several individual nutrients/foods are associated with uric acid status, the association of overall diet quality with hyperuricemia remains unclear. We thus examined the association between adherence to the dietary approaches to stop hypertension (DASH) diet and odds of having hyperuricemia in a Chin...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24150

    authors: Gao Y,Cui LF,Sun YY,Yang WH,Wang JR,Wu SL,Gao X

    更新日期:2020-01-21 00:00:00

  • Systemic lupus erythematosus in an African Caribbean population: incidence, clinical manifestations, and survival in the Barbados National Lupus Registry.

    abstract:OBJECTIVE:To assess the epidemiology, clinical features, and outcomes of systemic lupus erythematosus (SLE) in the predominantly African Caribbean population of Barbados. METHODS:A national registry of all patients diagnosed with SLE was established in 2007. Complete case ascertainment was facilitated by collaboration...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.21656

    authors: Flower C,Hennis AJ,Hambleton IR,Nicholson GD,Liang MH,Barbados National Lupus Registry Group.

    更新日期:2012-08-01 00:00:00

  • Traditional cardiovascular risk factors and coronary artery calcification in adults with polymyositis and dermatomyositis: a Danish multicenter study.

    abstract:OBJECTIVE:To determine the occurrence of traditional cardiovascular (CV) risk factors and coronary artery calcification (CAC) in adults with polymyositis (PM) or dermatomyositis (DM) compared to healthy controls and to assess the association between CV risk factors, PM/DM, and CAC score. METHODS:Traditional CV risk fa...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.22520

    authors: Diederichsen LP,Diederichsen AC,Simonsen JA,Junker P,Søndergaard K,Lundberg IE,Tvede N,Gerke O,Christensen AF,Dreyer L,Petersen H,Ejstrup L,Kay SD,Jacobsen S

    更新日期:2015-05-01 00:00:00

  • Impact of etanercept on work and activity impairment in employed moderate to severe rheumatoid arthritis patients in the United States.

    abstract:OBJECTIVE:To quantify the impact of etanercept on work and activity impairment in employed US patients with moderate to severe rheumatoid arthritis (RA). METHODS:This prospective, observational, longitudinal study recruited RA patients initiating etanercept (50 mg/week) between January 2009 and March 2010. The Work Pr...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.22022

    authors: Hone D,Cheng A,Watson C,Huang B,Bitman B,Huang XY,Gandra SR

    更新日期:2013-10-01 00:00:00

  • Relationship of intermuscular fat volume in the thigh with knee extensor strength and physical performance in women at risk of or with knee osteoarthritis.

    abstract:OBJECTIVE:To determine the extent to which thigh intermuscular fat (IMF) and quadriceps muscle (QM) volumes explained variance in knee extensor strength and physical performance in women with radiographic knee osteoarthritis (ROA) and without. METHODS:Baseline data from 125 women (age ≥50 years) in the Osteoarthritis ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.21868

    authors: Maly MR,Calder KM,Macintyre NJ,Beattie KA

    更新日期:2013-01-01 00:00:00

  • Association of Anemic Hypoxia and Increased Pulmonary Artery Systolic Pressure in Patients With Systemic Lupus Erythematosus.

    abstract:OBJECTIVE:Pulmonary arterial hypertension (PAH) is a rare but serious complication of systemic lupus erythematosus (SLE). Chronic hypoxia is known to cause PAH resulting from pulmonary vascular remodeling. We investigated the association between anemic hypoxia and PAH in SLE patients. METHODS:Systolic pulmonary artery...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.22630

    authors: Kim KJ,Baek IW,Yoon CH,Kim WU,Cho CS

    更新日期:2015-12-01 00:00:00

  • Pain, anxiety, and negative outcome expectations for activity: do negative psychological profiles differ between the inactive and active?

    abstract:OBJECTIVE:Adherence to physical activity at ≥150 minutes/week has proven to offer disease management and health-promoting benefits among adults with arthritis. While highly active people seem undaunted by arthritis pain and are differentiated from the moderately active by adherence-related psychological factors, knowle...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22421

    authors: Gyurcsik NC,Cary MA,Sessford JD,Flora PK,Brawley LR

    更新日期:2015-01-01 00:00:00

  • Late Nailfold Videocapillaroscopy Pattern Associated With Hand Calcinosis and Acro-Osteolysis in Systemic Sclerosis.

    abstract:OBJECTIVE:To determine whether calcinosis and acro-osteolysis are related to specific nailfold videocapillaroscopy (NVC) features in patients with systemic sclerosis (SSc; scleroderma). METHODS:NVC and bilateral hand radiographs were systematically performed in 155 consecutively recruited patients with SSc during a 24...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22672

    authors: Morardet L,Avouac J,Sammour M,Baron M,Kahan A,Feydy A,Allanore Y

    更新日期:2016-03-01 00:00:00

  • Trends in office visits during which opioids were prescribed for adults with arthritis: United States, 2006-2015.

    abstract:OBJECTIVE:To analyze trends in opioid prescriptions during visits to office-based physicians made by adults with arthritis in the US from 2006 to 2015. METHODS:We analyzed nationally representative data on patient visits to office-based physicians from the National Ambulatory Medical Care Survey (NAMCS) 2006-2015. Vis...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24447

    authors: Santo L,Schappert SM,Hootman JM,Helmick CG

    更新日期:2020-09-16 00:00:00

  • Patient Perspectives on Intravenous Biologics for Rheumatologic Disease.

    abstract:OBJECTIVE:Two surveys were conducted with patients with rheumatologic diseases to evaluate perceptions of different routes of administration (intravenous [IV] or subcutaneous [SC]) for biologic therapy. METHODS:In Survey I, patient preferences toward biologic treatment were evaluated at a rheumatology practice in Buff...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23758

    authors: Grisanti L,Kwiatkowski A,Dyrda P,Field E,Grisanti J,Hatem J,Dehoratius RJ,Gaylis N

    更新日期:2019-09-01 00:00:00

  • Association of peptic ulcer disease and pulmonary disease with risk of periprosthetic fracture after primary total knee arthroplasty.

    abstract:OBJECTIVE:To assess the association of specific comorbidities with periprosthetic fractures after primary total knee replacement (TKR). METHODS:We used the prospectively collected data in the Mayo Clinic total joint registry from 1989-2008 on all patients who had undergone primary TKR. The outcome of interest was post...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20548

    authors: Singh JA,Lewallen DG

    更新日期:2011-10-01 00:00:00

  • Clinical Remission and Low Disease Activity Outcomes Over 10 Years in Systemic Lupus Erythematosus.

    abstract:OBJECTIVE:A recent study conducted by our clinical group demonstrated that low disease activity (LDA), defined as a clinical Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) score ≤2, maintained for 12 months, confers the same risk for damage accrual as complete remission after 2 years. The aim of t...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23720

    authors: Tselios K,Gladman DD,Touma Z,Su J,Anderson N,Urowitz MB

    更新日期:2019-06-01 00:00:00

  • Utility and Associated Risk of Pulmonary Embolism Computed Tomography Scans in the Michigan Lupus Cohort.

    abstract:OBJECTIVE:Systemic lupus erythematosus patients are frequently evaluated for chest pain and may have multiple pulmonary embolism (PE) computed tomography (CT) scans. This study was undertaken to determine the incidence of pulmonary embolism in the University of Michigan Lupus Cohort patients who have undergone PE CT sc...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22684

    authors: Kado R,Siegwald E,Lewis E,Goodsitt MM,Christodoulou E,Kazerooni E,McCune WJ

    更新日期:2016-03-01 00:00:00

  • Efficiency Gains for Rheumatology Consultation Using a Novel Electronic Referral System in a Safety-Net Health Setting.

    abstract:OBJECTIVE:Health information technology (HIT) holds promise in increasing access to rheumatologists by improving the quality and efficiency of referrals, but few studies have examined its use for this purpose. We evaluated the use and impact of a novel electronic referral (eReferral) system in rheumatology in a safety-...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22559

    authors: Scheibe MM,Imboden JB,Schmajuk G,Margaretten M,Graf JD,Chen AH,Yelin EH,Yazdany J

    更新日期:2015-08-01 00:00:00

  • Factors explaining the discrepancy between physician and patient global assessment of joint and skin disease activity in psoriatic arthritis patients.

    abstract:OBJECTIVE:To assess the extent and determinants of discordance in scoring between patient global assessment (PtGA) and physician global assessment (PhGA) in patients with psoriatic arthritis (PsA). METHODS:A cross-sectional and longitudinal analysis of data was conducted in patients attending a large PsA clinic. The d...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22401

    authors: Eder L,Thavaneswaran A,Chandran V,Cook R,Gladman DD

    更新日期:2015-02-01 00:00:00

  • Pain, Fatigue, and Psychological Impact on Health-Related Quality of Life in Childhood-Onset Lupus.

    abstract:OBJECTIVE:To evaluate pain, fatigue, and psychological functioning of childhood-onset systemic lupus erythematosus (SLE) patients and examine how these factors impact health-related quality of life (HRQOL). METHODS:At a tertiary rheumatology clinic, 60 childhood-onset SLE patients completed the following: a visual ana...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.22650

    authors: Jones JT,Cunningham N,Kashikar-Zuck S,Brunner HI

    更新日期:2016-01-01 00:00:00

  • Effects of repetitive transcranial magnetic stimulation and multicomponent therapy in patients with fibromyalgia: a randomized controlled trial.

    abstract:OBJECTIVES:Fibromyalgia (FM) is a chronic painful condition partly due to alterations in pain modulation by the central nervous system. Multicomponent therapy (MT) and repetitive transcranial magnetic stimulation (rTMS) had both been reported as pain modulators in FM patients. The aim of this study was to compare the e...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24118

    authors: Guinot M,Maindet C,Hodaj H,Hodaj E,Bachasson D,Baillieul S,Cracowski JL,Launois S

    更新日期:2019-11-30 00:00:00

  • Access and cost-related non-adherence to prescription medications among lupus cases and controls: the Michigan Lupus Epidemiology & Surveillance (MILES) Program.

    abstract:BACKGROUND:Medication access and adherence are important determinants of health outcomes. We investigated factors associated with access and cost-related non-adherence to prescriptions in a population-based cohort of systemic lupus erythematosus (SLE) patients and controls. METHODS:Detailed sociodemographic and prescr...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.24397

    authors: Minhas D,Marder W,Harlow S,Hassett AL,Zick SM,Gordon C,Barbour KE,Helmick CG,Wang L,Lee J,Padda A,McCune WJ,Somers EC

    更新日期:2020-08-02 00:00:00

  • Dyspnea assessment and pulmonary hypertension in patients with systemic sclerosis: utility of the University of California, San Diego, Shortness of Breath Questionnaire.

    abstract:OBJECTIVE:The University of California in San Diego Shortness of Breath Questionnaire (UCSD SOBQ) has been used to assess dyspnea-related activity limitation in patients with airway and parenchymal lung disease. We sought to assess the construct validity and responsiveness of the UCSD SOBQ in systemic sclerosis (SSc; s...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.21827

    authors: Chung L,Chen H,Khanna D,Steen VD

    更新日期:2013-03-01 00:00:00

  • Using Physical Activity Trackers in Arthritis Self-Management: A Qualitative Study of Patient and Rehabilitation Professional Perspectives.

    abstract:OBJECTIVE:To compare and contrast the perspectives of patients with arthritis and those of rehabilitation professionals regarding starting and sustaining use of physical activity trackers (PATs). METHODS:We conducted focus group sessions with patients, physiotherapists, and occupational therapists in Ontario, Alberta,...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.23780

    authors: Leese J,Macdonald GG,Tran BC,Wong R,Backman CL,Townsend AF,Davis AM,Jones CA,Gromala D,Avina-Zubieta JA,Hoens AM,Li LC

    更新日期:2019-02-01 00:00:00

  • Association Between Biochemical Markers of Bone Turnover and Bone Changes on Imaging: Data From the Osteoarthritis Initiative.

    abstract:OBJECTIVE:To determine the relationship between biochemical markers involved in bone turnover and bone features on imaging in knees with osteoarthritis (OA). METHODS:We analyzed data from the Foundation for the National Institutes of Health OA Biomarkers Consortium within the Osteoarthritis Initiative (n = 600). Bone ...

    journal_title:Arthritis care & research

    pub_type: 杂志文章,多中心研究

    doi:10.1002/acr.23121

    authors: Deveza LA,Kraus VB,Collins JE,Guermazi A,Roemer FW,Bowes M,Nevitt MC,Ladel C,Hunter DJ

    更新日期:2017-08-01 00:00:00

  • Presence of peripheral arthritis and male sex predicting continuation of anti-tumor necrosis factor therapy in ankylosing spondylitis: an observational prospective cohort study from the South Swedish Arthritis Treatment Group Register.

    abstract:OBJECTIVE:To examine clinical characteristics as possible predictors of long-term treatment continuation with adalimumab, etanercept, and infliximab in ankylosing spondylitis (AS) patients who had never taken biologics treated in clinical practice. METHODS:Patients in southern Sweden with active AS starting biologic t...

    journal_title:Arthritis care & research

    pub_type: 杂志文章

    doi:10.1002/acr.20258

    authors: Kristensen LE,Karlsson JA,Englund M,Petersson IF,Saxne T,Geborek P

    更新日期:2010-10-01 00:00:00