当前位置： SCI文献检索 > JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA期刊下所有文献 > The Relevance of Postoperative Cognitive Decline in Daily Living: Results of a 1-Year Follow-up.

The Relevance of Postoperative Cognitive Decline in Daily Living: Results of a 1-Year Follow-up.

Abstract：

OBJECTIVES:Postoperative cognitive decline (POCD) has a perceivable influence on daily living and is noticed more often by close relatives than by patients themselves 3 months after aortic valve replacement. This study aimed to elucidate the longitudinal course of the subjective awareness of POCD. DESIGN:Follow-up of a prospective observational study. SETTING:A single cardiothoracic center in Germany. PARTICIPANTS:The study included 108 patients scheduled for elective aortic valve replacement surgery and 85 close relatives of the patients. INTERVENTIONS:In addition to conducting a neuropsychologic examination, the authors previously interviewed 82 patients with a Cognitive Failure Questionnaire for self-assessment (s-CFQ), and 62 relatives with the Cognitive Failure Questionnaire for others (f-CFQ) before and 3 months after surgery. Up until 12 months after surgery, the authors continuously interviewed additional patients (baseline and 3 months after surgery), thereby enlarging the original sample, and included the entire group (108 patients, 85 relatives) for the 12-month follow-up. RESULTS:The analysis showed that relatives (p = 0.026) and patients experienced patients' cognitive decline 3 months after surgery (p = 0.009). All changes still were observed in questions related to memory and attention. After 1 year, the s-CFQ no longer differed between baseline and postoperative assessment. Mean scores in the f-CFQ still were above baseline, barely missing statistical significance (p = 0.051). In patients with "change to worse" in the f-CFQ at 1-year follow-up, declining cognitive results in nonverbal learning (p = 0.021) could be observed 3 months postoperatively. Only a decrease in 3-month f-CFQ correlated with a decline in specific neuropsychologic tests 3 months after surgery. CONCLUSIONS:Contrary to the authors' previous results, the impact of POCD on daily living functions also was recognized by the patients themselves. The long-term influence and the associations between subjective deficits and psychometric cognitive measures seemed to be assessed more reliably by close relatives.

journal_name

J Cardiothorac Vasc Anesth

journal_title

Journal of cardiothoracic and vascular anesthesia

authors

Kastaun S,Gerriets T,Schwarz NP,Yeniguen M,Schoenburg M,Tanislav C,Juenemann M

doi

10.1053/j.jvca.2015.12.008

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

297-303

issue

eissn

1053-0770

issn

1532-8422

pii

S1053-0770(15)00969-6

journal_volume

pub_type

杂志文章

在线工具

The Relevance of Postoperative Cognitive Decline in Daily Living: Results of a 1-Year Follow-up.