Multilevel Corpectomy With Anterior Column Reconstruction and Plating for Subaxial Cervical Osteomyelitis.

Abstract:

STUDY DESIGN:A retrospective case series. OBJECTIVE:The aim of this study was to evaluate patients with cervical spine osteomyelitis who underwent multilevel (≥2) subaxial corpectomies and anterior column reconstruction and plating. SUMMARY OF BACKGROUND DATA:Neglected multilevel subaxial cervical osteomyelitis is a potentially dangerous disease. As it is rare, early radiographic and clinical outcomes after multilevel anterior corpectomy and reconstruction for subaxial cervical osteomyelitis are incompletely defined. METHODS:Adults who underwent multilevel corpectomy and anterior plating/reconstruction for subaxial cervical osteomyelitis at two institutions were reviewed. Analysis of patient demographics, operative details, and radiographic cervical alignment parameters [segmental kyphosis, cervical lordosis, C2-7 sagittal vertical axis (SVA)] was performed. RESULTS:Nineteen patients [15 males, four females; average age 48 years (20-81 yrs)] met inclusion criteria. The majority had pre-operative neurologic deficits or was immunosuppressed. All were treated with ≥6 weeks of intravenous antibiotics following operation. All had anterior plating/reconstruction with titanium cages (expandable-6; mesh-6) or structural bone graft (fibular allogaft-6; tricortical iliac crest-1). The average number of corpectomies was 2.4 (2-4). The average numbers of levels fused anteriorly was 4.4 (4-6) and posteriorly was 6.3 (4-9). The majority of patients (74%) was treated with an anterior/posterior approach. Average follow-up was 16 ± 9 months. There was significant improvement in all cervical alignment parameters (segmental kyphosis, C2-7 SVA, cervical lordosis). No intraoperative complications occurred and no patient deteriorated neurologically postoperatively. Postoperative complications included anterior cage/graft dislodgement (n = 2), recurrent neck hematomas requiring revision (n = 1), epidural hematoma (n = 1), and wound infection (n = 1). Sixty percent of patients had persistent neurologic dysfunction at final follow-up. None required reoperation for recurrent infection or pseudarthrosis. CONCLUSION:Although overall prognosis and neurologic recovery are guarded in medically fragile patients with multilevel subaxial cervical osteomyelitis, reconstruction with multilevel (≥2) corpectomy and anterior reconstruction/plating results in excellent restoration of cervical alignment and low rates of recurrent infection and pseudarthrosis. LEVEL OF EVIDENCE:4.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Theologis AA,Lansdown D,McClellan RT,Chou D,Pekmezci M

doi

10.1097/BRS.0000000000001557

subject

Has Abstract

pub_date

2016-09-15 00:00:00

pages

E1088-E1095

issue

18

eissn

0362-2436

issn

1528-1159

pii

00007632-201609150-00009

journal_volume

41

pub_type

杂志文章

相关文献

SPINE文献大全
  • Occupational low-back injury in a hospital employee population: an epidemiologic analysis of multiple risk factors of a high-risk occupational group.

    abstract::A case-control study was carried out using 84 cases of employee back injuries and 168 controls (matched triplets) at Children's Hospital and Health Center, San Diego. The objective was to examine the impact of multiple individual and work-related risk factors for low-back injury from hospital employee health records. ...

    journal_title:Spine

    pub_type: 杂志文章,评审

    doi:10.1097/00007632-198903000-00012

    authors: Ryden LA,Molgaard CA,Bobbitt S,Conway J

    更新日期:1989-03-01 00:00:00

  • A vertebral fracture in childhood is not a risk factor for disc degeneration but for Schmorl's nodes: a mean 40-year observational study.

    abstract:STUDY DESIGN:Observational cohort study. OBJECTIVE:To evaluate by MRI whether a vertebral fracture during childhood is a risk factor for degeneration of adjacent discs. SUMMARY OF BACKGROUND DATA:Several studies infer that trauma is a major cause of disc degeneration. Only 1 study has by magnetic resonance imaging (M...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181573d6a

    authors: Möller A,Maly P,Besjakov J,Hasserius R,Ohlin A,Karlsson MK

    更新日期:2007-10-15 00:00:00

  • Nucleus replacement device failure: a case report and biomechanical study.

    abstract:STUDY DESIGN:Case report and biomechanical study. OBJECTIVE:The objectives of this study were to report on a single case of a failed nucleus replacement device and to test the biomechanical properties of the failed device. SUMMARY OF BACKGROUND DATA:The use of spine arthroplasty techniques in the treatment of degener...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181dfbc78

    authors: Lindley EM,Jaafar S,Noshchenko A,Baldini T,Nair DP,Shandas R,Burger EL,Patel VV

    更新日期:2010-10-15 00:00:00

  • Morphologic differences of the vascular buds in the vertebral endplate: scanning electron microscopic study.

    abstract:STUDY DESIGN:Vascular buds in rabbit vertebral endplates were examined by scanning electron microscopy of corrosion casts. OBJECTIVES:To examine morphologic differences between vascular buds in two regions of the vertebral endplate (inner anular and nucleus pulposar). SUMMARY OF BACKGROUND DATA:Vascular buds are spec...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199601150-00003

    authors: Oki S,Matsuda Y,Shibata T,Okumura H,Desaki J

    更新日期:1996-01-15 00:00:00

  • A motivational scoring system for outcome prediction with spinal pain rehabilitation patients.

    abstract::The aim of this study is to demonstrate an effective method of testing using the Sixteen Personality Factor Questionnaire (16 PF) along with the Minnesota Multiphasic Personality Inventory (MMPI) to predict outcome criteria in a spinal pain clinic. Using an objective system of criteria for patient achievement, includi...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-198203000-00012

    authors: Lawlis GF,Mooney V,Selby DK,McCoy CE

    更新日期:1982-03-01 00:00:00

  • Cost-effectiveness analysis of extended conservative therapy versus surgical intervention in the management of herniated lumbar intervertebral disc.

    abstract::The management of herniated lumbar intervertebral disc for patients not responding to an initial trial of conservative therapy is generally surgical. Little is known about the effect of continued conservative therapy on patients who have not improved or have deteriorated within the first 3 months. This study assessed ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199202000-00010

    authors: Shvartzman L,Weingarten E,Sherry H,Levin S,Persaud A

    更新日期:1992-02-01 00:00:00

  • MRI Signal Intensity Classification in Cervical Ossification of the Posterior Longitudinal Ligament: Predictor of Surgical Outcomes.

    abstract:STUDY DESIGN:Prospective cohort study. OBJECTIVE:To investigate whether classification of increased signal intensity (ISI) on magnetic resonance imaging (MRI) of spinal cord in patients with cervical ossification of the posterior longitudinal ligament (C-OPLL) reflects severity of myelopathy and surgical outcome. SUM...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000001717

    authors: Ito K,Imagama S,Ito K,Ito Z,Ando K,Kobayashi K,Hida T,Tsushima M,Ishikawa Y,Matsumoto A,Machino M,Nishida Y,Ishiguro N,Kato F

    更新日期:2017-01-15 00:00:00

  • Atlantoaxial dislocation as the presenting symptom of ankylosing spondylitis.

    abstract::A 27-year-old woman presented with nontraumatic atlantoaxial dislocation that required a C1-C2 fusion. A comprehensive investigation initially failed to reveal any evidence of infectious or rheumatologic disease and she remained well for 3 1/2 years, at which time a diagnosis of ankylosing spondylitis was established....

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199311000-00037

    authors: Hamilton MG,MacRae ME

    更新日期:1993-11-01 00:00:00

  • Load-sharing characteristics of stabilized lumbar spine segments.

    abstract:STUDY DESIGN:Load sharing in stabilized spinal segments was evaluated using sequential injury and stabilization with a posterior instrumentation system under an in vitro flexibility protocol. OBJECTIVE:To analyze the partitioning of applied loads between anatomic and implanted structures of lumbar functional spinal un...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-200001150-00006

    authors: Cripton PA,Jain GM,Wittenberg RH,Nolte LP

    更新日期:2000-01-15 00:00:00

  • Radiological Evaluation of Craniocervical Region in Patients with Basilar Invagination.

    abstract:STUDY DESIGN:A retrospective analysis of collected data. OBJECTIVE:Our study aims to present the morphology of cranial-cervical spinal canal in basilar invagination (BI) patients. SUMMARY OF BACKGROUND DATA:BI is characterized by protrusion of the odontoid process into the foramen magnum (C0), leading to compression ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000002706

    authors: Ji W,Xu X,Wu Z,Liu X,Kong G,Huang Z,Chen J

    更新日期:2018-11-15 00:00:00

  • Acupuncture for neck disorders.

    abstract:STUDY DESIGN:Systematic review. OBJECTIVE:To determine the effects of acupuncture for individuals with neck pain. SUMMARY OF BACKGROUND DATA:Neck pain is one of the 3 most frequently reported complaints of the musculoskeletal system. Treatments for neck pain are varied, as are the perceptions of benefits. METHODS.: W...

    journal_title:Spine

    pub_type: 杂志文章,评审

    doi:10.1097/01.brs.0000252100.61002.d4

    authors: Trinh K,Graham N,Gross A,Goldsmith C,Wang E,Cameron I,Kay T

    更新日期:2007-01-15 00:00:00

  • Use and outcome of MRI in the surgical treatment of adolescent idiopathic scoliosis.

    abstract:STUDY DESIGN:Multicenter, prospective, consecutive clinical series. OBJECTIVE.: To report on the use and outcomes of preoperative magnetic resonance imaging (MRI) in a prospective cohort study of 2206 children undergoing posterior spinal fusion and instrumentation for adolescent idiopathic scoliosis. SUMMARY OF BACKGR...

    journal_title:Spine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/BRS.0b013e3181da218c

    authors: Diab M,Landman Z,Lubicky J,Dormans J,Erickson M,Richards BS,members of the Spinal Deformity Study Group.

    更新日期:2011-04-15 00:00:00

  • Highly Cited Works in Spinal Disorders: The Top 100 Most Cited Papers Published in Spine Journals.

    abstract:STUDY DESIGN:Bibliometric analysis. OBJECTIVE:To identify, and summarize the key findings of, the top 100 most highly cited works published in spinal disorder topic-specific journals. SUMMARY OF BACKGROUND DATA:There is an abundance of published articles pertaining to spine surgery and spinal disorders. The number of...

    journal_title:Spine

    pub_type: 杂志文章,评审

    doi:10.1097/BRS.0000000000002735

    authors: Badhiwala JH,Nassiri F,Witiw CD,Mansouri A,Alotaibi N,Eagles M,Almenawer SA,da Costa L,Wilson JR,Fehlings MG

    更新日期:2018-12-15 00:00:00

  • Left thoracic scoliosis configurations. Why so different?

    abstract:STUDY DESIGN:Patients in the scoliosis screening database were analyzed with respect to curve convexity, severity, and outcome, using standard statistical methods. OBJECTIVES:This study assessed whether left thoracic scoliosis is always pathologic and inquired why this is the case. SUMMARY OF BACKGROUND DATA:Left tho...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199406000-00013

    authors: Goldberg CJ,Dowling FE,Fogarty EE

    更新日期:1994-06-15 00:00:00

  • Predominant leg pain is associated with better surgical outcomes in degenerative spondylolisthesis and spinal stenosis: results from the Spine Patient Outcomes Research Trial (SPORT).

    abstract:STUDY DESIGN:As-treated analysis of the Spine Patient Outcomes Research Trial. OBJECTIVE:To compare baseline characteristics and surgical and nonoperative outcomes in degenerative spondylolisthesis (DS) and spinal stenosis (SpS) patients stratified by predominant pain location (i.e., leg vs. back). SUMMARY OF BACKGRO...

    journal_title:Spine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/BRS.0b013e3181d77c21

    authors: Pearson A,Blood E,Lurie J,Abdu W,Sengupta D,Frymoyer JW,Weinstein J

    更新日期:2011-02-01 00:00:00

  • Relationship between subjective neck disorders and cervical spine mobility and motion-related pain in male machine operators.

    abstract:STUDY DESIGN:In a single blinded procedure, quantified cervical clinical tests were performed on machine operators with and without subjective reports of neck pain. OBJECTIVES:To evaluate whether subjective reports of neck pain are associated with limited and painful cervical spine mobility. SUMMARY OF BACKGROUND DAT...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199707010-00015

    authors: Hagen KB,Harms-Ringdahl K,Enger NO,Hedenstad R,Morten H

    更新日期:1997-07-01 00:00:00

  • Saphenous nerve somatosensory evoked potentials: a novel technique to monitor the femoral nerve during transpsoas lumbar lateral interbody fusion.

    abstract:STUDY DESIGN:A retrospective analysis of a case series was performed. OBJECTIVE:To describe a novel technique to monitor femoral nerve function by analyzing the saphenous nerve somatosensory evoked potential (SSEP) during transpsoas surgical exposures of the lumbar spine. SUMMARY OF BACKGROUND DATA:During transpsoas ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000000357

    authors: Silverstein J,Mermelstein L,DeWal H,Basra S

    更新日期:2014-07-01 00:00:00

  • Intraoperative computed tomography with integrated navigation system in spinal stabilizations.

    abstract::STUDY DESIGN.: A prospective interventional case-series study plus a retrospective analysis of historical patients for comparison of data. OBJECTIVE.: To evaluate workflow, feasibility, and clinical outcome of navigated stabilization procedures with data acquisition by intraoperative computed tomography. SUMMARY OF BA...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181b77b19

    authors: Zausinger S,Scheder B,Uhl E,Heigl T,Morhard D,Tonn JC

    更新日期:2009-12-15 00:00:00

  • Coexistence of cervical and lumbar disc disease.

    abstract::A retrospective analysis of 200 patients requiring cervical disc surgery was performed to determine the frequency of coexistent lumbar disc or spine abnormalities. The duration of follow-up ranged from 5 to 25 years, averaging 14 years. Sixty percent were women and 40% were men, their ages ranging from 25-73 years. An...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199012000-00006

    authors: Jacobs B,Ghelman B,Marchisello P

    更新日期:1990-12-01 00:00:00

  • Absence of biglycan accelerates the degenerative process in mouse intervertebral disc.

    abstract:STUDY DESIGN:A study of the histologic changes of the intervertebral discs (IVDs) in biglycan (Bgn)-deficient mice. OBJECTIVE:In this study, we investigate whether the absence of Bgn accelerates the degenerative process in mouse intervertebral disc (IVD). SUMMARY OF BACKGROUND DATA:Proteoglycans and collagen fibrils ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181b7c7ec

    authors: Furukawa T,Ito K,Nuka S,Hashimoto J,Takei H,Takahara M,Ogino T,Young MF,Shinomura T

    更新日期:2009-12-01 00:00:00

  • Do Prophylactic Antibiotics Reach the Operative Site Adequately?: A Quantitative Analysis of Serum and Wound Concentrations of Systemic and Local Prophylactic Antibiotics in Spine Surgery.

    abstract:STUDY DESIGN:Prospective cohort study. OBJECTIVE:To analyze the serum and drain concentrations of antibiotics administered by two different routes and compare the results. SUMMARY OF BACKGROUND DATA:Systemic antibiotics are expected to reach the surgical site and maintain adequate concentrations of the drug to preven...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000003238

    authors: Naresh-Babu J,Arun-Kumar V

    更新日期:2020-02-15 00:00:00

  • Annulus fissures are mechanically and chemically conducive to the ingrowth of nerves and blood vessels.

    abstract:STUDY DESIGN:Mechanical and biochemical analyses of cadaveric and surgically removed discs. OBJECTIVE:To test the hypothesis that fissures in the annulus of degenerated human discs are mechanically and chemically conducive to the ingrowth of nerves and blood vessels. SUMMARY OF BACKGROUND DATA:Discogenic back pain is...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e318263ba59

    authors: Stefanakis M,Al-Abbasi M,Harding I,Pollintine P,Dolan P,Tarlton J,Adams MA

    更新日期:2012-10-15 00:00:00

  • The effects of an interspinous implant on the kinematics of the instrumented and adjacent levels in the lumbar spine.

    abstract:STUDY DESIGN:Measurement of the kinematics of the lumbar spine after insertion of an interspinous spacer in vitro. OBJECTIVES:To understand the kinematics of the instrumented and adjacent levels due to the insertion of this interspinous implant. SUMMARY OF BACKGROUND DATA:An interspinous spacer (X Stop, SFMT, Concord...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.BRS.0000084877.88192.8E

    authors: Lindsey DP,Swanson KE,Fuchs P,Hsu KY,Zucherman JF,Yerby SA

    更新日期:2003-10-01 00:00:00

  • Symptomatic intraosseous synovial cyst in the cervical spine: a case report.

    abstract:STUDY DESIGN:A case report and review of the literature are presented. OBJECTIVE:To describe an unusual location for a cervical synovial cyst and to review characteristic presentations and findings of synovial cysts in the cervical spine. SUMMARY OF BACKGROUND DATA:Synovial cysts in the cervical spine are rare. To da...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.BRS.0000090501.42188.2A

    authors: Jost SC,Hsien Tu P,Wright NM

    更新日期:2003-09-01 00:00:00

  • Sagittal alignment of the spine and pelvis during growth.

    abstract:STUDY DESIGN:Prospective study of the sagittal plane alignment of the spine and pelvis in the normal pediatric population. OBJECTIVES:To document the sagittal alignment of the spine and pelvis and its change during growth in the normal pediatric population. SUMMARY OF BACKGROUND DATA:Pelvic morphology as well as sagi...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.brs.0000132312.78469.7b

    authors: Mac-Thiong JM,Berthonnaud E,Dimar JR 2nd,Betz RR,Labelle H

    更新日期:2004-08-01 00:00:00

  • Genetic linkage localizes an adolescent idiopathic scoliosis and pectus excavatum gene to chromosome 18 q.

    abstract:STUDY DESIGN:A single large family, in which adolescent idiopathic scoliosis (AIS) and pectus excavatum (PE) segregate as an autosomal dominant condition, was evaluated. Genome-wide linkage analysis and candidate gene sequencing were performed. OBJECTIVE:To map the disease-causing locus in a large white family in whic...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e31818b88a5

    authors: Gurnett CA,Alaee F,Bowcock A,Kruse L,Lenke LG,Bridwell KH,Kuklo T,Luhmann SJ,Dobbs MB

    更新日期:2009-01-15 00:00:00

  • Necessity of rib head resection for anterior discectomy in the thoracic spine.

    abstract:STUDY DESIGN:The relation between the rib head and the thoracic disc was investigated anatomically. OBJECTIVES:To clarify the necessity of rib head resection in thoracoscopic discectomy using the anterior approach. SUMMARY OF BACKGROUND DATA:When using the transthoracic anterior approach, the rib head must often be r...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.brs.0000132516.03023.c4

    authors: Moro T,Kikuchi S,Konno S

    更新日期:2004-08-01 00:00:00

  • Matrix metalloproteinases: the clue to intervertebral disc degeneration?

    abstract:STUDY DESIGN:A review of the current literature on the role of matrix metalloproteinases in intervertebral disc degeneration. OBJECTIVE:To detail the characteristics of matrix metalloproteinases (classification, structure, substrate specificity and regulation) and to report previous studies of intervertebral discs. S...

    journal_title:Spine

    pub_type: 杂志文章,评审

    doi:10.1097/00007632-199807150-00021

    authors: Goupille P,Jayson MI,Valat JP,Freemont AJ

    更新日期:1998-07-15 00:00:00

  • Efficacy of hemivertebra resection for congenital scoliosis: a multicenter retrospective comparison of three surgical techniques.

    abstract:STUDY DESIGN:Multicenter, retrospective study. OBJECTIVE:To compare the outcomes of three surgical treatments for congenital spinal deformity due to a hemivertebra. SUMMARY OF BACKGROUND DATA:Congenital anomalies of the spine can cause significant and progressive scoliosis and kyphosis. Their management may be challe...

    journal_title:Spine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/BRS.0b013e318233f4bb

    authors: Yaszay B,O'Brien M,Shufflebarger HL,Betz RR,Lonner B,Shah SA,Boachie-Adjei O,Crawford A,Letko L,Harms J,Gupta MC,Sponseller PD,Abel MF,Flynn J,Macagno A,Newton PO

    更新日期:2011-11-15 00:00:00

  • Predicting Neurologic Recovery after Surgery in Patients with Deficits Secondary to MESCC: Systematic Review.

    abstract:STUDY DESIGN:Systematic literature review and expert survey OBJECTIVE.: The aim of this study was to determine factors associated with neurologic improvement in patients with neurologic deficits secondary to metastatic epidural spinal cord compression (MESCC). Clear understanding of these factors will guide surgical de...

    journal_title:Spine

    pub_type: 杂志文章,评审

    doi:10.1097/BRS.0000000000001827

    authors: Laufer I,Zuckerman SL,Bird JE,Bilsky MH,Lazáry Á,Quraishi NA,Fehlings MG,Sciubba DM,Shin JH,Mesfin A,Sahgal A,Fisher CG

    更新日期:2016-10-15 00:00:00