Matrix metalloproteinases: the clue to intervertebral disc degeneration?

abstract：STUDY DESIGN:A prospective study of 50 patients who underwent posterior thoracic or thoracolumbar instrumented spinal surgery from June 1998 through June 1999. OBJECTIVES:To highlight the advantages and disadvantages of neurogenic mixed evoked potential (NMEP) data obtained with three methods of stimulation: epidural,...

journal_title：Spine

authors： Wilson-Holden TJ,Padberg AM,Parkinson JD,Bridwell KH,Lenke LG,Bassett GS

更新日期：2000-09-15 00:00:00

abstract：STUDY DESIGN:Multicenter, prospective analysis of consecutive patients with adult spinal deformity (ASD). OBJECTIVE:Identify age-related radiographical parameters associated with poor health-related quality of life (HRQOL) and treatment preferences for ASD. SUMMARY OF BACKGROUND DATA:Patients with ASD report discrepa...

journal_title：Spine

authors： Fu KM,Bess S,Shaffrey CI,Smith JS,Lafage V,Schwab F,Burton DC,Akbarnia BA,Ames CP,Boachie-Adjei O,Deverin V,Hart RA,Hostin R,Klineberg E,Gupta M,Kebaish K,Mundis G,Mummaneni PV,International Spine Study Group.

更新日期：2014-08-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort study. OBJECTIVE:The fusion risk score (FRS) is introduced to assess baseline risk of spine fusion surgery preoperatively. An objective method of stratifying risk allows the surgeon to control risk through tailoring intervention and explain differences in complication profile in high-...

journal_title：Spine

authors： Hartin NL,Mehbod AA,Joglekar SB,Transfeldt EE

更新日期：2013-12-01 00:00:00

abstract：STUDY DESIGN:Case series. OBJECTIVE:To present the difficulty of diagnosing the origin of lower leg pain in patients with lumbar spinal stenosis and hip joint arthritis. SUMMARY OF BACKGROUND DATA:Pain arising from a degenerated hip joint is sometimes localized to the lower leg. Patients with lumbar spinal disease ma...

journal_title：Spine

authors： Saito J,Ohtori S,Kishida S,Nakamura J,Takeshita M,Shigemura T,Takazawa M,Eguchi Y,Inoue G,Orita S,Takaso M,Ochiai N,Kuniyoshi K,Aoki Y,Ishikawa T,Arai G,Miyagi M,Kamoda H,Suzuki M,Sakuma Y,Oikawa Y,Kubota G,In

更新日期：2012-12-01 00:00:00

abstract：STUDY DESIGN:This study was an exploratory repeated measures design comparing patients undergoing two magnitudes of surgery in the lumbar spine: lumbar herniated disc repair and posterior lumbar fusion. OBJECTIVE:The present study evaluated and compared the effect of perceived pain, perceived stress, anxiety, and mood...

journal_title：Spine

authors： Starkweather AR,Witek-Janusek L,Nockels RP,Peterson J,Mathews HL

更新日期：2006-08-15 00:00:00

abstract：STUDY DESIGN:Retrospective comparative cohort study. OBJECTIVE:Assess the incidence, risk factors, and outcomes of recurrent proximal junctional kyphosis (r-PJK) in PJK revision patients. SUMMARY OF BACKGROUND DATA:Several studies have identified the incidence and risk factors for PJK after primary surgery. However, ...

journal_title：Spine

authors： Kim HJ,Wang SJ,Lafage R,Iyer S,Shaffrey C,Mundis G,Hostin R,Burton D,Ames C,Klineberg E,Gupta M,Smith J,Schwab F,Lafage V,International Spine Study Group.

更新日期：2020-01-01 00:00:00

abstract：STUDY DESIGN:A finite element model of the ligamentous cervical spinal segment was used to compute loads in various structures in response to clinically relevant loading modes. OBJECTIVE:To predict biomechanical parameters, including intradisc pressure, tension in ligaments, and forces across facets that are not pract...

journal_title：Spine

authors： Goel VK,Clausen JD

更新日期：1998-03-15 00:00:00

abstract：STUDY DESIGN:Retrospective review of 750 consecutive multilevel cervical spine decompression surgeries performed by a single spine surgeon. OBJECTIVE:To determine the incidence of C5 palsy in a large consecutive series of multilevel cervical spine decompression procedures. SUMMARY OF BACKGROUND DATA:Palsy of the C5 n...

journal_title：Spine

authors： Nassr A,Eck JC,Ponnappan RK,Zanoun RR,Donaldson WF 3rd,Kang JD

更新日期：2012-02-01 00:00:00

abstract：STUDY DESIGN:Retrospective review of prospectively-collected, multicenter adult spinal deformity (ASD) database. OBJECTIVE:The aim of this study was to evaluate the rate of patients who accrue catastrophic cost (CC) with ASD surgery utilizing direct, actual costs, and determine the feasibility of predicting these outl...

journal_title：Spine

authors： Ames CP,Smith JS,Gum JL,Kelly M,Vila-Casademunt A,Burton DC,Hostin R,Yeramaneni S,Lafage V,Schwab FJ,Shaffrey CI,Bess S,Pellisé F,Serra-Burriel M,European Spine Study Group and International Spine Study Group.

更新日期：2020-03-01 00:00:00

abstract：:A posterolateral technique to decompress retropulsed bone from the spinal canal has been employed in nine patients, confirmed with intraoperative canal inspection and pre- and postoperative computed axial tomographic (CAT) evaluation. This technique has allowed reduction of retropulsed bony elements from the spinal ca...

journal_title：Spine

authors： Garfin SR,Mowery CA,Guerra J Jr,Marshall LF

更新日期：1985-04-01 00:00:00

abstract：STUDY DESIGN:Consecutive case-series. OBJECTIVE:The main purpose of this study was to analyze the relationship between the preoperative neurological status and subsequent survival of patients undergoing surgical treatment for symptomatic spinal metastases. SUMMARY OF BACKGROUND DATA:The survival of cancer patients ha...

journal_title：Spine

authors： Vanek P,Bradac O,Trebicky F,Saur K,de Lacy P,Benes V

更新日期：2015-12-01 00:00:00

abstract：STUDY DESIGN:Observational study of patients with scoliosis and matched controls. OBJECTIVES:To determine the validity and reliability of the modified Scoliosis Research Society Outcomes Instrument (SRS-22) for use in the assessment of deformity in adults. To demonstrate the discriminate validity of the SRS-22 in diff...

journal_title：Spine

authors： Berven S,Deviren V,Demir-Deviren S,Hu SS,Bradford DS

更新日期：2003-09-15 00:00:00

abstract：STUDY DESIGN:Retrospective case review of children completing dual growing rod treatment at our institutions. Patients had a minimum of 2 years follow-up. OBJECTIVE:To identify the factors influencing dual growing rod treatment outcome followed to final fusion. SUMMARY OF BACKGROUND DATA:Published reports on dual gro...

journal_title：Spine

authors： Akbarnia BA,Breakwell LM,Marks DS,McCarthy RE,Thompson AG,Canale SK,Kostial PN,Tambe A,Asher MA,Growing Spine Study Group.

更新日期：2008-04-20 00:00:00

abstract：STUDY DESIGN:A new magnetic resonance image analysis method is proposed which is based on the definition of the borders of the vertebral bodies adjacent to the intervertebral disc and their varying relationships. The reproducibility of this method (the so-called "centroid" method) was assessed by consecutive measuremen...

journal_title：Spine

authors： Boos N,Wallin A,Aebi M,Boesch C

更新日期：1996-03-01 00:00:00

abstract：STUDY DESIGN:Retrospective study. OBJECTIVE:Evaluate the relationship among the neurologic status, the Thoracolumbar Injury Classification System (TLICS) score, and the Magerl/AO classification system. SUMMARY OF THE BACKGROUND DATA:A wide range of classification schemes for thoracic and lumbar spine trauma have been...

journal_title：Spine

authors： Joaquim AF,Fernandes YB,Cavalcante RA,Fragoso RM,Honorato DC,Patel AA

更新日期：2011-01-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort study of the American College of Surgeons National Surgical Quality Improvement Program database from 2011 to 2012. OBJECTIVE:Minimizing the morbidity of posterior cervical fusion can be improved with identification of patient risk factors. SUMMARY OF BACKGROUND DATA:Posterior cervic...

journal_title：Spine

authors： Medvedev G,Wang C,Cyriac M,Amdur R,O'Brien J

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:Retrospective study of instrumentation failure after posterior vertebral column resection (pVCR) in adult spinal deformity (ASD) patients. OBJECTIVE:The morbidity and related risk factors of the instrumentation failure. SUMMARY OF BACKGROUND DATA:Instrumentation failure is another common complication aft...

journal_title：Spine

authors： Wang H,Guo J,Wang S,Yang Y,Zhang Y,Qiu G,Zhang J

更新日期：2017-04-01 00:00:00

abstract：STUDY DESIGN:Compression-induced changes in the concentration of substance P and VIP (vasoactive intestinal polypeptide), in spinal nerve roots and dorsal root ganglia were studied in an experimental nerve root compression model in pigs. OBJECTIVES:To analyze by radioimmunoassay the concentration of the neuropeptides ...

journal_title：Spine

authors： Cornefjord M,Olmarker K,Farley DB,Weinstein JN,Rydevik B

更新日期：1995-03-15 00:00:00

abstract：STUDY DESIGN:As-treated analysis of the Spine Patient Outcomes Research Trial. OBJECTIVE:To compare baseline characteristics and surgical and nonoperative outcomes in degenerative spondylolisthesis (DS) and spinal stenosis (SpS) patients stratified by predominant pain location (i.e., leg vs. back). SUMMARY OF BACKGRO...

journal_title：Spine

authors： Pearson A,Blood E,Lurie J,Abdu W,Sengupta D,Frymoyer JW,Weinstein J

更新日期：2011-02-01 00:00:00

abstract：STUDY DESIGN:Validity and responsiveness study using a randomized clinical trial and prospective cohort study of patients with low back pain (LBP). OBJECTIVE:To provide evidence for construct validity and responsiveness to change of a single-item presenteeism question (SIPQ) in patients with LBP. SUMMARY OF BACKGROUN...

journal_title：Spine

authors： Kigozi J,Lewis M,Jowett S,Barton P,Coast J

更新日期：2014-03-01 00:00:00

abstract：:A retrospective review of 326 female patients with untreated idiopathic scoliosis was performed to determine what factors might be useful in predicting the risk of curve progression. Components such as family history, height-weight ratio, lumbosacral transitional anomalies, kyphosis, lordosis, and trunk balance were n...

journal_title：Spine

authors： Bunnell WP

更新日期：1986-10-01 00:00:00

abstract：STUDY DESIGN:Two case reports of telangiectatic osteosarcoma treated with complete segmental resection of the spine, including the spinal cord. OBJECTIVES:To report the en bloc tumor excision, including the spinal cord, for telangiectatic osteosarcoma, and discuss the indication of cord transection and influence after...

journal_title：Spine

authors： Murakami H,Tomita K,Kawahara N,Oda M,Yahata T,Yamaguchi T

更新日期：2006-02-15 00:00:00

abstract：STUDY DESIGN:Narrative review of the literature and commentary. OBJECTIVE:To discuss from an epidemiological and sociological perspective whether the early clinical management of whiplash-associated disorders can lead to iatrogenic disability. SUMMARY OF BACKGROUND DATA:There is a lack of evidence supporting the effe...

journal_title：Spine

authors： Côté P,Soklaridis S

更新日期：2011-12-01 00:00:00

abstract：:Spinal stenosis should be considered in the differential diagnosis of disc disease when evaluating an adolescent presenting with unrelenting back and leg pain. Although they typically exhibit mechanical signs alone without neurological findings, they nevertheless may prove more vulnerable to rapidly progressive neurol...

journal_title：Spine

authors： Epstein NE,Epstein JA,Carras R

更新日期：1988-08-01 00:00:00

abstract：STUDY DESIGN:Patients in the scoliosis screening database were analyzed with respect to curve convexity, severity, and outcome, using standard statistical methods. OBJECTIVES:This study assessed whether left thoracic scoliosis is always pathologic and inquired why this is the case. SUMMARY OF BACKGROUND DATA:Left tho...

journal_title：Spine

authors： Goldberg CJ,Dowling FE,Fogarty EE

更新日期：1994-06-15 00:00:00

abstract：STUDY DESIGN:A quasi 3-dimensional pathologic survey of tears in the L4-L5 disc. OBJECTIVE:To seek accurate information on the pathogenesis and outcomes of tears to facilitate correlation with radiologic imaging and biomechanical testing; and to improve laboratory models for testing hypotheses of disc function and fai...

journal_title：Spine

authors： Vernon-Roberts B,Moore RJ,Fraser RD

更新日期：2007-12-01 00:00:00

abstract：STUDY DESIGN:Cross-sectional study. OBJECTIVE:To assess the inter- and intraobserver reliability of thoracic, spino-pelvic, and rod lengthening measurements made on biplanar spinal stereoradiography (EOS imaging) in children treated with magnetically controlled growing rod (MCGR). SUMMARY OF BACKGROUND DATA:MCGR trea...

journal_title：Spine

authors： Obid P,Yiu KKL,Cheung KM,Kwan K,Ruf M,Cheung JPY

更新日期：2018-11-15 00:00:00

abstract：STUDY DESIGN:This is a case report of a posterior extrusion of the polyethylene core from a CHARITÉ arthroplasty. This is the first reported case of posterior dislocation of the polyethylene and the revision strategies used to correct this problem. OBJECTIVE:To report a novel failure mechanism and revision strategy fo...

journal_title：Spine

authors： Eskander MS,Onyedika II,Eskander JP,Connolly PJ,Eck JC,Lapinsky A

更新日期：2010-11-15 00:00:00

abstract：STUDY DESIGN:Three transaxial slices, dividing each disc into four layers of equal thickness, were made in each of 19 T12-L1 discs. Naked-eye and stereoscopic examination was used to record abnormalities of the T12 (superior) surface of the upper slice, opposing surfaces of the central slice, and the L1 (inferior) surf...

journal_title：Spine

authors： Vernon-Roberts B,Fazzalari NL,Manthey BA

更新日期：1997-11-15 00:00:00

abstract：:The role of thermography for diagnosing lumbar radiculopathy was evaluated by literature review and meta-analysis. From 81 relevant citations, 28 studies could be analyzed for diagnostic-accuracy data (sensitivity and specificity) and method. Diagnostic-accuracy data varied significantly between studies; therefore mea...

journal_title：Spine

authors： Hoffman RM,Kent DL,Deyo RA

更新日期：1991-06-01 00:00:00