Influence of the Preoperative Neurological Status on Survival After the Surgical Treatment of Symptomatic Spinal Metastases With Spinal Cord Compression.


STUDY DESIGN:Consecutive case-series. OBJECTIVE:The main purpose of this study was to analyze the relationship between the preoperative neurological status and subsequent survival of patients undergoing surgical treatment for symptomatic spinal metastases. SUMMARY OF BACKGROUND DATA:The survival of cancer patients has increased over recent years with improvements in oncologic therapy. As many as 70% of cancer patients develop spinal metastases and ∼10% of all cancer patients are treated for metastatic spinal cord compression. METHODS:We retrospectively analyzed 166 patients who underwent surgery for symptomatic spinal metastases in our department between 2005 and 2012. The evaluated factors were age, primary tumor aggressiveness (slow, moderate, rapid growing), spinal location (cervical, thoracic, lumbar, and sacral), operation type (posterior decompression, anterior or posterior instrumented procedure, and radical combined instrumented surgery), preoperative evaluation using the revised Tokuhashi scoring system (<9, 9-11, and 12-15), pre- and postoperative neurological status according to the Frankel score (A-C and D-E), and the site of the main spinal cord compression (anterior, posterior, or combined). Postoperative complication and recurrence rate were also monitored. RESULTS:The mean age of the patients was 62 ± 12 years. The median survival time after surgery was 16.0 months. Preoperative neurological status influenced survival time significantly; the median survival was 5.1 months in Frankel A-C and 28.2 months in Frankel D-E (P < 0.001). Improvement on the Frankel scale did not influence the survival time (P = 0.131). When the patients' age was <65 years this related to a significantly longer survival time (P = 0.046). The Tokuhashi score predicted patient's survival independently (P < 0.001). The other factors had no statistical significance. CONCLUSION:The most important factors influencing postoperative survival time of these patients with symptomatic spinal metastases was the preoperative neurological condition and the Tokuhashi scoring system, which together represents a useful tool for planning the extent of surgical treatment.


Spine (Phila Pa 1976)




Vanek P,Bradac O,Trebicky F,Saur K,de Lacy P,Benes V




Has Abstract


2015-12-01 00:00:00














  • Posterior vertebral column resection in fixed lumbosacral deformity.

    abstract:STUDY DESIGN:Retrospective study. OBJECTIVES:To report the results and the technique of posterior vertebral column resection (PVCR) in fixed lumbosacral deformity. SUMMARY OF BACKGROUND DATA:Fixed lumbosacral deformity has gross imbalance as well as progressive compensatory thoracolumbar deformity because of the abse...


    pub_type: 杂志文章


    authors: Suk SI,Chung ER,Lee SM,Lee JH,Kim SS,Kim JH

    更新日期:2005-12-01 00:00:00

  • A Profile of Low Back Pain: Treatment and Costs Associated With Patients Referred to Orthopedic Specialists in Sweden.

    abstract:STUDY DESIGN:Analysis of Swedish national and regional register data. OBJECTIVES:The aim of this study was to characterize healthcare resource utilization, productivity loss, and costs of patients with low back pain (LBP) with or without leg pain, who have been referred from primary care settings to orthopedic special...


    pub_type: 杂志文章


    authors: Jonsson E,Olafsson G,Fritzell P,Hägg O,Borgström F

    更新日期:2017-09-01 00:00:00

  • Self-assembling Peptide Reduces Glial Scarring, Attenuates Posttraumatic Inflammation, and Promotes Neurite Outgrowth of Spinal Motor Neurons.

    abstract:STUDY DESIGN:Self-assembling peptide gel (SPG-178) provides new evidence for the role of a scaffold for treatment of the spinal cord through induction of neuroprotective factors. OBJECTIVE:To verify the reproducibility of SPG-178 as scaffold after spinal cord injury, we examine the characteristics of SPG-178 and prote...


    pub_type: 杂志文章


    authors: Ando K,Imagama S,Ito Z,Kobayashi K,Hida T,Nakashima H,Ito K,Tsushima M,Ishikawa Y,Matsumoto A,Nishida K,Nishida Y,Ishiguro N

    更新日期:2016-10-15 00:00:00

  • Construct validity and responsiveness of the single-item presenteeism question in patients with lower back pain for the measurement of presenteeism.

    abstract:STUDY DESIGN:Validity and responsiveness study using a randomized clinical trial and prospective cohort study of patients with low back pain (LBP). OBJECTIVE:To provide evidence for construct validity and responsiveness to change of a single-item presenteeism question (SIPQ) in patients with LBP. SUMMARY OF BACKGROUN...


    pub_type: 杂志文章


    authors: Kigozi J,Lewis M,Jowett S,Barton P,Coast J

    更新日期:2014-03-01 00:00:00

  • Defining Avoidable and Unavoidable Complications in Spine Surgery: A Survey-based Study of Spine Fellowship Directors.

    abstract:STUDY DESIGN:A cross-sectional survey of orthopedic spine surgery fellowship directors in the United States. OBJECTIVE:The aim of this study was to investigate whether consensus exists with respect to spine-related adverse events and certain hospital-acquired conditions (HACs) or "never events." SUMMARY OF BACKGROUND...


    pub_type: 杂志文章


    authors: Khaleel MA,Bono CM,White AP,Wood KB,Harris MB,Wagner K,Zurakowski D,McGuire KJ

    更新日期:2016-06-01 00:00:00

  • Long adult deformity fusions to L5 and the sacrum. A matched cohort analysis.

    abstract:STUDY DESIGN:A matched cohort analysis of long adult deformity fusions according to distal fusion level (L5 vs. S1). OBJECTIVE.: To compare the results of long adult deformity fusions to either L5 or the sacrum in the presence of a "healthy" 5-1 disc using a matched cohort analysis. SUMMARY OF BACKGROUND DATA:For adul...


    pub_type: 杂志文章,评审


    authors: Edwards CC 2nd,Bridwell KH,Patel A,Rinella AS,Berra A,Lenke LG

    更新日期:2004-09-15 00:00:00

  • Administration of sodium ibandronate in the treatment of complicated giant cell tumor of the spine.

    abstract:STUDY DESIGN:Case study. OBJECTIVE:To present three complicated cases of giant cell tumor of the spine treated with sodium ibandronate. SUMMARY OF BACKGROUND DATA:Spinal giant cell tumors are a rare clinical entity with a high recurrence rate after operation. Furthermore, complete resection of such lesions remains a ...


    pub_type: 杂志文章


    authors: Zhang W,Zhang Y,Li P,Rhodesm SD,Wang Y,Xue X,Dong Y,Ding W,Shen Y,Zhang B

    更新日期:2011-08-01 00:00:00

  • Spinal evoked potentials from the cervical spine.

    abstract::Spinal cord evoked potentials were recorded from spinous processes of the lumbar, thoracic, and cervical levels of the spinal column of normal cats in response to direct stimulation of the sciatic nerve and subcutaneous stimulation of the posterior tibial nerve. The typical primary response was altered by changes in l...


    pub_type: 杂志文章


    authors: Reger SI,Henry DT,Whitehill R,Wang GJ,Stamp WG

    更新日期:1979-11-01 00:00:00

  • Decision making in the surgical treatment of cervical spine metastases.

    abstract:STUDY DESIGN:Qualitative systematic review of the literature. OBJECTIVE:To determine whether surgical indications and techniques are influenced by the region of the cervical spine (occipitocervical, midcervical, and cervicothoracic junctions). SUMMARY OF BACKGROUND DATA:There are distinct differences in the anatomic ...


    pub_type: 杂志文章,评审


    authors: Fehlings MG,David KS,Vialle L,Vialle E,Setzer M,Vrionis FD

    更新日期:2009-10-15 00:00:00

  • Spontaneous cervical spinal epidural hematoma in the postpartum period.

    abstract:STUDY DESIGN:We present the case study of a 31-year-old lady who had a spontaneous cervical spinal epidural hematoma in the postpartum period and who presented with sudden onset of neck pain and lower limb weakness for which an emergency decompressive laminectomy was performed with neurological recovery. OBJECTIVE:To ...


    pub_type: 杂志文章


    authors: Puah KL,Tow BP,Yue WM,Guo CM,Chen JL,Tan SB

    更新日期:2012-03-15 00:00:00

  • Acute pyogenic sacroiliitis without predisposing conditions.

    abstract:STUDY DESIGN:Clinical and imaging findings of patients diagnosed with pyogenic sacroiliitis were retrospectively analyzed. OBJECTIVES:To characterize the clinical and magnetic resonance features of patients with acute pyogenic sacroiliitis without the usually known predisposing conditions and to investigate the diagno...


    pub_type: 杂志文章


    authors: Doita M,Yoshiya S,Nabeshima Y,Tanase Y,Nishida K,Miyamoto H,Watanabe Y,Kurosaka M

    更新日期:2003-09-15 00:00:00

  • Monitoring of lumbosacral nerve roots during spinal instrumentation.

    abstract::A technique is described for intraoperative, multimodality electrophysiologic monitoring of the spinal cord and lumbosacral nerve roots (cauda equina). Simultaneous monitoring with the techniques of electromyography, compound muscle action potentials, and somatosensory evoked potentials is found to provide highly usef...


    pub_type: 杂志文章


    authors: Hormes JT,Chappuis JL

    更新日期:1993-10-15 00:00:00

  • Extrusion of expandable stacked interbody device for lumbar fusion: case report of a complication.

    abstract:STUDY DESIGN:A case report. OBJECTIVE:We report on the device failure of a polyetherether-ketone expandable cage device with posterior migration of one of its components. SUMMARY OF BACKGROUND DATA:Posterior migration of transforaminal lumbar interbody fusion cage devices has been reported with static devices, and ou...


    pub_type: 杂志文章


    authors: Kim PD,Baron EM,Levesque M

    更新日期:2012-08-15 00:00:00

  • Zebris versus Myrin: a comparative study between a three-dimensional ultrasound movement analysis and an inclinometer/compass method: intradevice reliability, concurrent validity, intertester comparison, intratester reliability, and intraindividual variab

    abstract:STUDY DESIGN:Experimental study. OBJECTIVES:To compare two devices for measuring cervical range of motion, a three-dimensional ultrasound motion device (Zebris) and a gravity-reference goniometer (Myrin). SUMMARY OF BACKGROUND DATA:Assessment of cervical range of motion is used to evaluate the effect of different tre...


    pub_type: 杂志文章


    authors: Malmström EM,Karlberg M,Melander A,Magnusson M

    更新日期:2003-11-01 00:00:00

  • Vibration modes of injured spine at resonant frequencies under vertical vibration.

    abstract:STUDY DESIGN:A detailed three-dimensional finite element model of the spine segment T12-Pelvis was developed to investigate dynamic characteristics of whole lumbar spine with injured cases. OBJECTIVE:This study investigates the motion mechanism of the human lumbar spine and the effect of component injuries on adjacent...


    pub_type: 杂志文章


    authors: Guo LX,Zhang M,Zhang YM,Teo EC

    更新日期:2009-09-01 00:00:00

  • A systematic review of cross-cultural adaptation of the neck disability index.

    abstract:STUDY DESIGN:Systematic review of cross-cultural adaptation. OBJECTIVE:To perform a systematic review of cross-cultural adaptations of the Neck Disability Index (NDI) and to give a critical assessment to improve its translation. SUMMARY OF BACKGROUND DATA:The NDI is used to assess functional capacity and physical act...


    pub_type: 杂志文章,评审


    authors: Yao M,Sun YL,Cao ZY,Dun RL,Yang L,Zhang BM,Jiang HR,Wang YJ,Cui XJ

    更新日期:2015-04-01 00:00:00

  • A Computed Tomography Study of the C7 Vertebra Screws Fixation in Children.

    abstract:STUDY DESIGN:Retrospective analysis of computed tomographic images of 92 normal pediatric cervical vertebrae. OBJECTIVE:The aim of this study was to ascertain the feasibility of the pedicle, intralaminar, and lateral mass screws fixation in children. SUMMARY OF BACKGROUND DATA:Fixation techniques of C7 vertebrae are ...


    pub_type: 杂志文章


    authors: Liu J,Ji W,Huang Z,Kong G,Liu Q,Huang Z,Wu X,Zhu Q

    更新日期:2018-12-15 00:00:00

  • Radiation exposure to the spine surgeon in lumbar and thoracolumbar fusions with the use of an intraoperative computed tomographic 3-dimensional imaging system.

    abstract:STUDY DESIGN:A prospective clinical research article. OBJECTIVE:The primary goals were to determine (1) radiation exposure to the spine surgeon with the use of an intraoperative 3-dimensional imaging system and (2) to define the safe distance from the computed tomographic scanner. SUMMARY OF BACKGROUND:Intraoperative...


    pub_type: 临床试验,杂志文章


    authors: Abdullah KG,Bishop FS,Lubelski D,Steinmetz MP,Benzel EC,Mroz TE

    更新日期:2012-08-01 00:00:00

  • Selective arterial embolization with n-butyl cyanoacrylate in the treatment of aneursymal bone cyst of the thoracic vertebra: a case report.

    abstract:STUDY DESIGN:A case report of aneurysmal bone cyst of the mobile spine. OBJECTIVE:To present a pediatric case of aneurysmal bone cyst (ABC) of the mobile spine treated successfully by selective arterial embolization (SAE) with n-butyl cyanoacrylate (NBCA). SUMMARY OF BACKGROUND DATA:The endovascular treatment is an i...


    pub_type: 杂志文章


    authors: Marushima A,Matsumaru Y,Suzuki K,Takigawa T,Kujiraoka Y,Anno I,Matsumura A

    更新日期:2009-03-15 00:00:00

  • Time Demand and Radiation Dose in 3D-Fluoroscopy-based Navigation-assisted 3D-Fluoroscopy-controlled Pedicle Screw Instrumentations.

    abstract:STUDY DESIGN:Prospective single-center cohort study to record additional time requirements and radiation dose in navigation-assisted O-arm-controlled pedicle screw (PS) instrumentations. OBJECTIVE:The aim of this study was to evaluate amount of extra-time and radiation dose for navigation-assisted PS instrumentations ...


    pub_type: 杂志文章


    authors: Balling H

    更新日期:2018-05-01 00:00:00

  • Psychosocial Variables Contribute to Length of Stay and Discharge Destination After Lumbar Surgery Independent of Demographic and Clinical Variables.

    abstract:STUDY DESIGN:Prospective analysis of resource utilization (RU) after lumbar surgery. OBJECTIVE:To determine contributions of patient psychosocial variables to RU, specifically length of stay (LOS) and discharge destination. SUMMARY OF BACKGROUND DATA:Associations between demographic/clinical variables and RU are well...


    pub_type: 杂志文章


    authors: Mancuso CA,Duculan R,Craig CM,Girardi FP

    更新日期:2018-02-15 00:00:00

  • Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.

    abstract:STUDY DESIGN:We report on a 54-year-old man with chronic lower back pain after recent streptococcus pneumoniae pulmonary infection, resulting in a mycotic aortic aneurysm and spondylodiscitis of the eighth vertebrae 6 months later. Successful surgical treatment and recurrence-free survival after 4 years are described. ...


    pub_type: 杂志文章


    authors: Englert C,Aebert H,Lenhart M,Solleder A,Nerlich M,Neumann C

    更新日期:2004-09-01 00:00:00

  • The applied anatomy of the thoracolumbar fascia.

    abstract::The thoracolumbar fascia was studied by dissection in ten adult human cadavers. The posterior layer of this fascia was found to consist of two laminae. The superficial lamina is formed by the aponeurosis of latissimus dorsi. The deep lamina consists of bands of fibers passing caudolaterally from the midline. Both lami...


    pub_type: 杂志文章


    authors: Bogduk N,Macintosh JE

    更新日期:1984-03-01 00:00:00

  • Outcomes Following Arthrodesis for Atlanto-Axial Osteoarthritis.

    abstract:STUDY DESIGN:Retrospective analysis. OBJECTIVE:We set out to evaluate the radiographic and patient-reported outcomes following C1-C2 arthrodesis for atlantoaxial osteoarthritis (AAOA) using modern instrumentation and techniques. SUMMARY OF BACKGROUND DATA:Few studies have evaluated outcomes following C1-C2 arthrodesi...


    pub_type: 杂志文章


    authors: Kang DG,Lehman RA Jr,Wagner SC,Peters C,Riew KD

    更新日期:2017-03-01 00:00:00

  • Secondary prevention of low-back pain. A clinical trial.

    abstract::A clinical trial, aimed at secondary prevention of low-back pain, was performed in 142 hospital employees reporting at least three annual episodes of this condition. Participants were randomly assigned to one of three groups: a calisthenics program (CAL) for 3 months with biweekly sessions of flexion exercises, a back...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Donchin M,Woolf O,Kaplan L,Floman Y

    更新日期:1990-12-01 00:00:00

  • Juvenile idiopathic scoliosis: the effectiveness of part-time bracing.

    abstract:STUDY DESIGN:A retrospective review of 34 patients with juvenile idiopathic scoliosis (JIS) treated with a nighttime bending brace. OBJECTIVE:To determine the effectiveness of part-time bracing in JIS. SUMMARY OF BACKGROUND DATA:Although previous bracing studies have focused on adolescent idiopathic scoliosis, no aut...


    pub_type: 杂志文章


    authors: Jarvis J,Garbedian S,Swamy G

    更新日期:2008-05-01 00:00:00

  • Textiloma: A Case of Foreign Body Mimicking a Spinal Tumor.

    abstract:STUDY DESIGN:Case report OBJECTIVE.: To report a case of foreign body mimicking spinal tumor. SUMMARY OF BACKGROUND DATA:Gossypiboma or more broadly retained foreign object is a surgical complication resulting from foreign materials such as cotton or gauze pads and surgical sponge, accidentally left inside a patient's...


    pub_type: 杂志文章


    authors: Meshkini A,Salehpour F,Rezakhah A,Mirzaei F,Kazemzadeh M,Naseri Alavi SA

    更新日期:2017-11-01 00:00:00

  • Morphometry of the cervical spinal cord and its relation to pathology in cases with compression myelopathy.

    abstract::The purpose of this study was to determine whether or not computerized tomography myelography (CTM) gave an actual size and shape of the cervical spinal cord, and whether such dimensions reflected pathology of the spinal cord in cases suffering from compression myelopathy. Spinal cord transverse area and compression r...


    pub_type: 杂志文章


    authors: Fujiwara K,Yonenobu K,Hiroshima K,Ebara S,Yamashita K,Ono K

    更新日期:1988-11-01 00:00:00

  • Cervical sagittal alignment in idiopathic scoliosis treated by posterior instrumentation and in situ bending.

    abstract:STUDY DESIGN:Retrospective radiographical analysis of cervical and thoracolumbar sagittal alignment in young adults with idiopathic scoliosis. OBJECTIVE:To analyze cervical alignment types, the relationship between cervical and thoracolumbar alignment and the effect of posterior instrumentation. SUMMARY OF BACKGROUND...


    pub_type: 杂志文章


    authors: Charles YP,Sfeir G,Matter-Parrat V,Sauleau EA,Steib JP

    更新日期:2015-04-01 00:00:00

  • The injured canine cervical spine after six months of healing. An in vitro three-dimensional study.

    abstract::The cervical spine is a common site of spinal injuries. The stability of an injured cervical spine is not only dependent on injury severity, but also on the degree of healing time. Using a canine model, three injuries of varying degrees of severity were surgically produced at the C4-C5 level and allowed to heal for 6 ...


    pub_type: 杂志文章


    authors: Crisco JJ,Panjabi MM,Wang E,Price MA,Pelker RR

    更新日期:1990-10-01 00:00:00