Absence of biglycan accelerates the degenerative process in mouse intervertebral disc.

abstract：STUDY DESIGN:Randomized, controlled trial. OBJECTIVE:To evaluate a four-session self-management group intervention for patients with pain in primary care, led by trained lay persons with back pain. The intervention was designed to reduce patient worries, encourage self-care, and reduce activity limitations. BACKGROUN...

journal_title：Spine

authors： Von Korff M,Moore JE,Lorig K,Cherkin DC,Saunders K,González VM,Laurent D,Rutter C,Comite F

更新日期：1998-12-01 00:00:00

abstract：STUDY DESIGN:A retrospective analysis of the clinical outcomes of eight patients with the lumbar pars interarticulars defects treated by direct repair with the aid of intraoperative O-arm based navigation and microendoscopic techniques. OBJECTIVE:The aim of this study was to investigate the efficacy and safety of dire...

journal_title：Spine

authors： Jia M,Wang J,Zhang Z,Zheng W,Zhou Y

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:The efficacy of intrathecal (spinal) morphine in the treatment of pain after posterior spinal fusions was assessed. OBJECTIVE:To investigate improved posterior pain control with fewer side effects in patients with posterior spinal fusions. SUMMARY OF BACKGROUND DATA:After multilevel spinal fusion with in...

journal_title：Spine

authors： Urban MK,Jules-Elysee K,Urquhart B,Cammisa FP,Boachie-Adjei O

更新日期：2002-03-01 00:00:00

abstract：STUDY DESIGN:Prospective measurement of rhBMP-2 from drains in a cohort of patients undergoing posterolateral spinal fusion. OBJECTIVE:To quantify the amount of rhBMP-2 that extravasates into drains after posterolateral fusion using its current commercially available form, rhBMP-2 within an absorbable collagen sponge....

journal_title：Spine

authors： Mok JM,Durrani SK,Piper SL,Hu SS,Deviren V,Berven SH,Burch S

更新日期：2008-07-01 00:00:00

abstract：STUDY DESIGN:Exploratory subgroup analysis in a randomized controlled trial (RCT). OBJECTIVE:To detect possible moderators in the effectiveness of a workplace intervention in a population of workers with sick leave due to sub acute nonspecific low back pain. SUMMARY OF BACKGROUND DATA:In a recently published RCT, a w...

journal_title：Spine

authors： Steenstra IA,Knol DL,Bongers PM,Anema JR,van Mechelen W,de Vet HC

更新日期：2009-05-20 00:00:00

abstract：:Biopsy or subtotal resection followed by radiation for intramedullary astrocytomas of the spinal cord offer palliation but not cure. A treatment modality using an ultrasonic suction device has revolutionized the treatment of these tumors and has been extended to include the treatment of intramedullary tumors involving...

journal_title：Spine

authors： Benzel EC,Mirfarkhraee M,Hadden T,Fowler M

更新日期：1987-10-01 00:00:00

abstract：STUDY DESIGN:We performed a retrospective study of spinal roentgenograms of a large cohort of patients suffering from osteogenesis imperfecta. OBJECTIVE:To determine the prevalence of vertebral pars defects (spondylolysis) in patients with osteogenesis imperfecta. SUMMARY OF BACKGROUND DATA:Patients suffering from os...

journal_title：Spine

authors： Verra WC,Pruijs HJ,Beek EJ,Castelein RM

更新日期：2009-06-01 00:00:00

abstract：STUDY DESIGN:Cross-sectional study to evaluate the thoracic and lumbar spine in patients with diastrophic dysplasia (DD). OBJECTIVES:To find the causative factors behind the spinal deformities and restricted mobility of the spine. SUMMARY OF BACKGROUND DATA:Typical findings in this skeletal dysplasia are short-limbed...

journal_title：Spine

authors： Remes V,Tervahartiala P,Poussa M,Peltonen J

更新日期：2001-01-15 00:00:00

abstract：STUDY DESIGN:This study prospectively analyzed gait in 21 patients with flatback and reviewed radiographs and charts. OBJECTIVE:To analyze the effect of sagittal imbalance on gait and hip and knee joints. SUMMARY OF BACKGROUND DATA:Loss of lumbar lordosis causes anterior displacement of the center of gravity, which c...

journal_title：Spine

authors： Sarwahi V,Boachie-Adjei O,Backus SI,Taira G

更新日期：2002-11-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort study. OBJECTIVE:To identify early independent mortality predictors after spine trauma. SUMMARY OF BACKGROUND DATA:Spine trauma consists of spinal cord and spine column injury. The ability to identify early (within 24 hours) risk factors predictive of mortality in spine trauma has th...

journal_title：Spine

authors： Tee JW,Chan PC,Gruen RL,Fitzgerald MC,Liew SM,Cameron PA,Rosenfeld JV

更新日期：2013-01-15 00:00:00

abstract：STUDY DESIGN:Posture and motion analysis after a Cotrel-Dubousset instrumentation. OBJECTIVES:To investigate the compensation role of pelvis. SUMMARY OF BACKGROUND DATA:Few existing studies found no compensation at the lower unfused level but did not investigate the pelvis. METHODS:Thirty patients were analyzed befo...

journal_title：Spine

authors： Skalli W,Zeller RD,Miladi L,Bourcereau G,Savidan M,Lavaste F,Dubousset J

更新日期：2006-05-20 00:00:00

abstract：STUDY DESIGN:A retrospective study investigated the progression risk of juvenile scoliosis until skeletal maturity or spinal fusion. OBJECTIVES:To define risk factors of curve progression during pubertal growth and analyze the timing of arthrodesis. SUMMARY OF BACKGROUND DATA:Juvenile scoliosis is characterized by a ...

journal_title：Spine

authors： Charles YP,Daures JP,de Rosa V,Diméglio A

更新日期：2006-08-01 00:00:00

abstract：STUDY DESIGN:A case of lumbar metastasis of a choriocarcinoma is presented. OBJECTIVE:To present and review a rare case of metastatic choriocarcinoma in the lumbar spine. SUMMARY OF BACKGROUND DATA:Choriocarcinoma is a highly anaplastic malignancy derived from trophoblastic cells characterized by the secretion of hum...

journal_title：Spine

authors： Naito Y,Akeda K,Kasai Y,Matsumine A,Tabata T,Nagao K,Uchida A

更新日期：2009-07-01 00:00:00

abstract：STUDY DESIGN:Clinical study. OBJECTIVE:To investigate the feasibility of the transoral endoscopic odontoidectomy without occipitocervical fusion. SUMMARY OF BACKGROUND DATA:Endoscopic transnasal resection of the odontoid process is less invasive than the conventional transoral odontoidectomy. However, the endonasal a...

journal_title：Spine

authors： Qiuhang Z,Feng K,Bo Y,Hongchuan G,Mingchu L,Ge C,Feng L

更新日期：2013-06-15 00:00:00

abstract：STUDY DESIGN:Animal model study of three healthy commercial pigs was conducted. OBJECTIVE:To determine whether near infrared spectroscopic monitoring of the spinal cord is feasible, and whether changes in near infrared spectroscopy correlate with changes in blood flow to the cord or operative maneuvers. SUMMARY OF BA...

journal_title：Spine

authors： Macnab AJ,Gagnon RE,Gagnon FA

更新日期：2002-01-01 00:00:00

abstract：STUDY DESIGN AND OBJECTIVES:The effects of nerve root retraction in posterior discectomy on pressure, blood flow, and electrophysiologic changes of the nerve root were investigated. OBJECTIVES:This study was performed to assess the effects of nerve root retraction in posterior discectomy on pressure, blood flow, and e...

journal_title：Spine

authors： Matsui H,Kitagawa H,Kawaguchi Y,Tsuji H

更新日期：1995-03-15 00:00:00

abstract：STUDY DESIGN:This study compared direct measurements of the distances between the vertebral arteries in the cervical spines of human cadaver specimens with data obtained from axial computed tomography images of these specimens. OBJECTIVE:To determine whether the information obtained from a computed tomography scan can...

journal_title：Spine

authors： Heary RF,Albert TJ,Ludwig SC,Vaccaro AR,Wolansky LJ,Leddy TP,Schmidt RR

更新日期：1996-09-15 00:00:00

abstract：:This article reports a prospective, randomized, multicentered study documenting changes in the intensity and location of low-back and referred pain to repeated end-range lumbar flexion and extension movements performed first while standing and then while recumbent during a single clinical patient evaluation. Significa...

journal_title：Spine

authors： Donelson R,Grant W,Kamps C,Medcalf R

更新日期：1991-06-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort comparative study. OBJECTIVE:To determine the prevalence of major complications, identify risk factors, and assess long-term clinical benefit after revision adult spinal deformity surgery. SUMMARY OF BACKGROUND DATA:No study has analyzed risk factors for major complications in long r...

journal_title：Spine

authors： Cho SK,Bridwell KH,Lenke LG,Yi JS,Pahys JM,Zebala LP,Kang MM,Cho W,Baldus CR

更新日期：2012-03-15 00:00:00

abstract：STUDY DESIGN:Clinical findings of spinal stenosis were compared to graded radiologic findings of dural sac narrowing. OBJECTIVES:To examine the changes of the dural sac area of the lumbar spine on computerized tomography (CT) performed without and with axial loading, and study the correlations between the radiologic f...

journal_title：Spine

authors： Lohman CM,Tallroth K,Kettunen JA,Lindgren KA

更新日期：2006-07-15 00:00:00

abstract：:The major objective of this investigation was to study the effectiveness of the physical conditioning program used at the University of Miami Comprehensive Pain and Rehabilitation Center in restoring certain elements of the functional abilities of individuals suffering from chronic low-back pain and to evaluate the ef...

journal_title：Spine

authors： Khalil TM,Asfour SS,Martinez LM,Waly SM,Rosomoff RS,Rosomoff HL

更新日期：1992-03-01 00:00:00

abstract：STUDY DESIGN:Retrospective study using a national administrative database. OBJECTIVE:To define the cohort differences in patient characteristics between patients undergoing cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) in a large national sample, and to describe the impact of thos...

journal_title：Spine

authors： Goz V,Martin BI,Donnally CJ 3rd,Brodke D,Spina N,Lawrence B,Spiker WR

更新日期：2020-07-15 00:00:00

abstract：STUDY DESIGN:Prospective cross-sectional measurement study. OBJECTIVE:To determine the ability of the Scoliosis Research Society (SRS)-22 questionnaire to discriminate among management and scoliosis severity subgroups and to correlate with internal and external measures of curve severity. SUMMARY OF BACKGROUND DATA:I...

journal_title：Spine

authors： Parent EC,Hill D,Mahood J,Moreau M,Raso J,Lou E

更新日期：2009-10-15 00:00:00

abstract：STUDY DESIGN:Retrospective analysis of national insurance billing database. OBJECTIVE:To examine trends in reoperation after single-level lumbar discectomy. SUMMARY OF BACKGROUND DATA:Lumbar discectomy is the most commonly performed procedure for treatment of radiculopathy caused by disc herniation. Randomized clinic...

journal_title：Spine

authors： Heindel P,Tuchman A,Hsieh PC,Pham MH,D'Oro A,Patel NN,Jakoi AM,Hah R,Liu JC,Buser Z,Wang JC

更新日期：2017-04-15 00:00:00

abstract：STUDY DESIGN:A multicenter assessor-blinded randomized clinical trial was conducted. OBJECTIVES:To investigate the difference in effectiveness of manipulative therapy and interferential therapy for patients with acute low back pain when used as sole treatments and in combination. SUMMARY OF BACKGROUND DATA:Both manip...

journal_title：Spine

authors： Hurley DA,McDonough SM,Dempster M,Moore AP,Baxter GD

更新日期：2004-10-15 00:00:00

abstract：STUDY DESIGN:Case-control study. OBJECTIVE:To examine factors influencing cervical alignment after corrective surgery for adult patients with adolescent idiopathic scoliosis (AdIS) SUMMARY OF BACKGROUND DATA.: Corrective surgery for spinal deformity influences postoperative cervical spinal alignment, but changes in th...

journal_title：Spine

authors： Nagoshi N,Yagi M,Daimon K,Suzuki S,Tsuji O,Okada E,Fujita N,Nakamura M,Matsumoto M,Watanabe K

更新日期：2020-07-01 00:00:00

abstract：STUDY DESIGN:A retrospective radiographical follow-up study of thoracolumbar deformity in 33 children with mucopolysaccharidosis 1 (Hurler syndrome). OBJECTIVE:To report the severity, natural history, risk factors for progression, and results of intervention for thoracolumbar kyphosis in children with Hurler syndrome....

journal_title：Spine

authors： Yasin MN,Sacho R,Oxborrow NJ,Wraith JE,Williamson JB,Siddique I

更新日期：2014-03-01 00:00:00

abstract：STUDY DESIGN:Retrospective case series. OBJECTIVE:To evaluate the accuracy of screw fixation using intraoperative three-dimensional fluoroscopy-based navigation (ITFN) and to assess the clinical outcomes of this treatment regimen. SUMMARY OF BACKGROUND DATA:The surgical management of symptomatic os odontoideum poses ...

journal_title：Spine

authors： Weng C,Tian W,Li ZY,Liu B,Li Q,Wang YQ,Sun YZ

更新日期：2012-10-01 00:00:00

abstract：STUDY DESIGN:Evaluation of a possible correlation of clinical symptoms of chronic low back pain (LBP) patients before and after application of external spinal fixation (ESF) with three-dimensional motion patterns. OBJECTIVE:To determine whether the intervertebral kinematics in chronic LBP patients correlate with pain ...

journal_title：Spine

authors： Lund T,Oxland TR,Nydegger T,Schlenzka D,Laine T,Heini P

更新日期：2002-12-01 00:00:00

abstract：STUDY DESIGN:The pretension of the Dynesys cord was varied to evaluate its effects on both tissue responses and screw-spacer behaviors by the finite-element method. OBJECTIVE:This study aimed to provide detailed information about the motion-preserving and load-shielding mechanisms of the Dynesys screw-spacer joint. S...

journal_title：Spine

authors： Chien CY,Tan CH,Lu TH,Lin SC,Chuang WH,Chiang MC,Luh YP,Chen YJ

更新日期：2013-06-01 00:00:00