Abstract：
UNLABELLED:Due to the increasing number of elderly as well as chronically-ill patients, venous thrombosis assumes an increasing role as a typical complication of many courses of disease. Postoperatively, in patients without anticoagulation, fibrinogen tests show venous thrombosis in the lower extremities in up to 50% but not all were clinically relevant. Prophylactic treatment has markedly lowered the manifestation of deep venous thrombosis. Nevertheless, in current epidemiologic studies, the prevalence of thrombotic disease is three-fold higher (1:7,500) than that of bleeding diseases (1:20,000). PATHOGENESIS:Congenital deficiency or congenital dysfunction of inhibitors of activated clotting factors have provided insight into the functional principles of limited proteolysis. Unequivocal causes of recurrent thrombosis are deficiency or dysfunction of AT III, protein C, protein S or plasminogen (Figure 1). Dysfibrinogenemia, in about 10% of the patients, leads to a tendency to thrombosis. Unclarified remains the relevance of lowered values for factor XII, heparin-cofactor II (HC II) and histidine-rich glycoprotein (HRG) (Table 1). Congenital disorders usually manifest themselves in the early adulthood. For the clinical manifestation of venous thrombosis, imbalance between pro-coagulatory and inhibitor factors are of importance, therefore the compensatory capabilities of other protease inhibitors, for example, alpha-2-macroglobulin should be taken into consideration. In acquired lowering of hemostasis factors, the balance in the plasma protein cascade should be assessed (Figure 1).(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Herzjournal_title
Herzauthors
Schramm W,Spannagl Msubject
Has Abstractpub_date
1989-12-01 00:00:00pages
323-8issue
6eissn
0340-9937issn
1615-6692journal_volume
14pub_type
杂志文章,评审相关文献
HERZ文献大全abstract：:The standardized and constant fixed-dose rate, no necessity for a close and regular blood monitoring as well as the small number of interactions with other drugs and daily food make therapy with the new oral anticoagulants dabigatran and rivaroxaban and in future presumably apixaban much easier and more feasible than ...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-012-3619-8
更新日期：2012-06-01 00:00:00
abstract：:Despite the almost complete disappearance of the so called "postperfusion lung syndrome" after cardiac surgery with extracorporeal circulation (ECC), there is still a need for respiratory treatment in some cases, primarily for cardio-circulatory or respiratory reasons. In addition postoperative artificial ventilation ...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：:Over the past decade there has been a steady proliferation of indices which have been proposed for assessing ventricular function. Many of these indices are based on single measurements and often are insensitive and have limited clinical utility. The present article focuses on the role of wall stress in assessing vent...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1981-10-01 00:00:00
abstract：BACKGROUND:Short-term prognosis of patients with chest pain and angiographically smooth coronary arteries is good in terms of development of coronary events (fatal or nonfatal myocardial infarction, coronary death, new coronary heart disease), but long-term studies are rare. PATIENTS AND METHODS:185 consecutive patien...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-003-2295-0
更新日期：2003-08-01 00:00:00
abstract：:Interventional treatment of mitral insufficiency has recently become possible on a limited basis. The developed percutaneous procedures aim at minimizing the trauma in high-risk surgical candidates. Echocardiography has a major role in the preinterventional evaluation, during the interventional procedure, and in the p...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-009-3281-y
更新日期：2009-09-01 00:00:00
abstract：:Plasma catecholamines and hemodynamic were assessed in 32 patients with heart failure of varying degrees due to coronary artery disease as well as in twelve healthy control subjects. The studies employed the use of a (Swan-Ganz) semi-floating, balloon-tipped, thermodilution catheter during supine bicycle ergometry at ...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：:As a result of an aging, increasingly obese, and decreasingly physically active population, the global incidence and prevalence of type 2 diabetes mellitus (DM) is increasing. While little can be done to influence the contribution of aging to the increasing global prevalence of diabetes, opportunities abound to develo...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-004-2605-1
更新日期：2004-08-01 00:00:00
abstract：:The presence of intraventricular obstruction is a powerful predictor of outcome in patients with hypertrophic cardiomyopathy (HCM) and, when associated with severe, drug-refractory symptoms, should be managed aggressively. Resting left ventricular outflow obstruction is found in approximately 20% of the patients, clas...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-006-2928-1
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Epidemiologic studies have found an association between overweight and increased mortality arising primarily from cardiovascular disorders. A major determinant is a chronically raised sympathetic nervous system activity which can arise from calorie intake-dependent and -independent mechanisms. Calorie-depend...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-003-2517-5
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:This study aimed to investigate the impact of metabolic syndrome (MetS) with microalbuminuria on the improvement of cardiac function after acute myocardial infarction (AMI). METHODS:Nondiabetic patients with acute ST segment elevation MI (STEMI) who underwent coronary revascularization from 2013 to 2017 wer...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-020-04918-y
更新日期：2020-05-11 00:00:00
abstract：:Chronic heart failure has an age-dependent prevalence of 2% and is therefore one of the most frequent diseases in western societies. A reduced hemoglobin concentration according to the definition of the World Health Organization is a common comorbidity affecting more than half of all heart failure patients. Elderly pa...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-3901-4
更新日期：2013-09-01 00:00:00
abstract：:Atrial fibrillation (AF) is the most frequently encountered sustained arrhythmia with a prevalence of 0.5-10%, depending predominantly on age. The arrhythmia is associated with significant morbidity and mortality, mainly due to thromboembolic events including stroke and systemic embolisms. These complications can be e...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-017-4648-0
更新日期：2018-02-01 00:00:00
abstract：:Coronary artery disease is still the no. 1 killer in the developed countries and must thus be detected and treated at an earlier stage. If coronary artery disease is advanced, patients have to be examined regarding the need for revascularization. For secondary prevention, of course, an optimal change of life style and...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/pl00001975
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:Renal denervation (RDN) has been proposed as a novel antihypertensive intervention for treating resistant hypertension. It remains to be investigated which patient groups can potentially benefit from RDN. The present study aimed to evaluate the efficacy and safety of RDN in patients with mild-moderate resist...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-017-4664-0
更新日期：2019-08-01 00:00:00
abstract：:Reducing cardiac mortality and improving quality of life are the main objectives of cardiac rehabilitation. In recent years, outpatient rehabilitation within easy patient reach has achieved the same status as inpatient rehabilitation. Outpatient rehabilitation permits close involvement of the patient's family and soci...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-011-3557-x
更新日期：2012-02-01 00:00:00
abstract：:In a medical out-patient clinic, over a period of several years, atrial myxoma was diagnosed in four patients with ages ranging between 32 and 69 years. With the exception of one patient referred for assessment of ventricular premature beats, presentation was not primarily attributable to cardiac causes. In all patien...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：:The European Society of Cardiology (ESC) has recently published new guidelines on the diagnosis and management of chronic coronary syndromes (CCS). Due to variable symptoms, objective tests are often necessary to confirm the diagnosis, exclude alternative diagnoses, and assess the severity of underlying disease. This ...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-020-04935-x
更新日期：2020-08-01 00:00:00
abstract：:Preliminary results are reported using 201Tl-myocardial scintigraphy (MSC) with quantitated analysis of redistribution kinetics immediately after ergometry (climbing step test) two to four hours later respectively and (Dual-ROI-) Equilibrium-Radionuclide-Ventriculography (ERNVG) with 99mTc-in vivo-labeled erythrocytes...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:A 68-year-old woman was admitted to hospital because of chronic heart failure. The cause was a left-right shunt between the left sinus of Valsalva and the right atrium. The patient underwent surgery with shunt closure. Intraoperatively, the ramus circumflexus of the coronary artery was occluded. 2.5 years later the pa...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-009-3216-7
更新日期：2009-05-01 00:00:00
abstract：:The 12-lead surface electrocardiogram (ECG) is of great importance for the diagnostics of cardiac arrhythmias. For the correct and systematic analysis it has a sensitivity and specificity for the correct diagnosis of supraventricular tachycardia or ventricular tachycardia of more than 95%. Nevertheless, the assessment...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-018-4684-4
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:The prognostic importance of high-sensitivity cardiac troponin T (hs-cTnT) has recently been reported in patients with heart failure. The myocardial performance index (MPI), which combines parameters of both systolic and diastolic ventricular function, provides a better marker of left ventricular dysfunction...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-015-4322-3
更新日期：2015-11-01 00:00:00
abstract：:The prevalence of overweight and obesity in children and adolescents is increasing. In Germany, 10-20% of children and youth are overweight and obese. Childhood obesity is associated with cardiovascular and other comorbidities. 25% suffer from arterial hypertension and/or hypercholesterolemia, 1% from diabetes mellitu...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-006-2860-4
更新日期：2006-09-01 00:00:00
abstract：:Although viral myocarditis has been mostly attributed to enterovirus and adenovirus infection until recently, the association with parvovirus B19 in Europe and hepatitis C virus in Asia has lately been noted. Clinical trials of antiviral agents, such as interferons, are in progress. Whereas immunosuppression with cort...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-007-3037-5
更新日期：2007-09-01 00:00:00
abstract：:Cardiovascular (CV) risk assessment is based on the utilization of risk scores, enabling clinicians to estimate an individual's risk to develop CV pathologies and events. Such risk scores comprise classic CV risk factors such as smoking, diabetes, hypertension, and blood cholesterol levels. Recently, other CV biomarke...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-019-04874-2
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:It is believed that most myocardial infarctions result from the rupture of "vulnerable plaques", that share certain common characteristics. These plaques typically consist of a lipid-rich core in the central portion of the thickened intima, covered by a thin friable fibrous cap. Today, one of the important c...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-003-2485-9
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Modern high-resolution imaging techniques have provided new insights into the pathogenesis of aortic dissection during recent years. Distinct pathologic entities or potential precursors of classic false-lumen aortic dissection such as intramural hematoma or penetrating atherosclerotic ulcer have been identif...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-002-2406-3
更新日期：2002-09-01 00:00:00
abstract：PURPOSE:This article describes the potential of dynamic contrast- enhanced magnetic resonance tomography (DCE-MRT) for the visualization and quantification of blood flow of lower leg muscles at rest and after individually adjusted muscular exercise. PATIENTS AND METHODS:Five cases were chosen to exemplify the qualitat...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-004-2532-1
更新日期：2004-02-01 00:00:00
abstract：:At present, in patients with diabetes mellitus and coronary multivessel disease no fixed general recommendation can be given in favor or to the disadvantage of surgical revascularization or in favor or to the disadvantage of percutaneous coronary intervention (PCI). In cases with an evidence-based indication for coron...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-010-3342-2
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:We aimed to investigate the predictive value of the fibrinogen-to-albumin ratio (FAR) regarding the development of major cardiovascular events (MACE) in patients treated with percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). METHODS:This was a prospective, observational cohort stud...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-019-4840-5
更新日期：2020-12-01 00:00:00
abstract：:In patients with chronic coronary artery disease different therapeutic strategies, such as optimal medical therapy, revascularization by percutaneous coronary intervention or coronary artery bypass grafting have been shown to improve the prognosis and symptoms and yield proven superiority over other treatment strategi...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-3803-5
更新日期：2013-06-01 00:00:00
