Egg Production and Donation: A New Frontier in the Global Landscape of Cross-Border Reproductive Care: Ethical Concerns.

abstract：:Conventional biochemical assays are performed via an averaging procedure with the lysate of a large number of target cells; however, the averaged data lose information regarding the heterogeneity of individual cells. For quantitative assay of single cells, it is necessary to isolate single cells, extract cellular comp...

journal_title：Current pharmaceutical biotechnology

authors： Sasaki A,Sakata H,Kinjo M

更新日期：2010-01-01 00:00:00

abstract：:As sessile and filter-feeding metazoans, marine sponges represent an ecologically important and highly diverse component of marine benthic communities throughout the world. It has been suggested that marine sponges are hosts to many microorganisms which can constitute up to 40-60% of its biomass. Recently, sponges hav...

journal_title：Current pharmaceutical biotechnology

authors： Santos-Gandelman JF,Giambiagi-deMarval M,Oelemann WM,Laport MS

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Restoration of blood flow during ischemic stroke leads to cerebral ischemia reperfusion injury (CIRI) by activating neuroinflammatory cascades. Pomelo peel volatile oil (PPVO) extracted from Citrus maxima (Burm.) from the genus Rutaceae, comprises some anti-inflammatory ingredients, such as limonene and β-my...

journal_title：Current pharmaceutical biotechnology

authors： Tian XY,Xie L,Wang WY,Zou XS,Zhao GY,Chen MH

更新日期：2020-12-30 00:00:00

abstract：:Progress in many therapies, in particular in the therapies based on peptides, proteins and nucleic acids used as bioactive compounds, strongly depends on development of appropriate carriers which would be suitable for controlled delivery of the intact abovementioned compounds to required tissues, cells and intracellul...

journal_title：Current pharmaceutical biotechnology

authors： Slomkowski S,Gosecki M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Up to 25% of diabetic patients will develop a diabetic foot ulcer. Chronic wounds such as diabetic foot ulcers often fail to heal with conventional therapies. In recent years, it has been identified that chronic wounds are usually associated with elevated level of matrix metalloproteinases (MMPs). Doxycyclin...

journal_title：Current pharmaceutical biotechnology

authors： Xu DH,Zhu Z,Fang Y

更新日期：2017-01-01 00:00:00

abstract：:The biliary secretion of bile acids is critical for multiple liver functions including digesting fatty nutrients and driving bile flow. When this process is impaired, the accumulating bile acids cause inflammatory liver injury. Multiple ABC transporters in the liver are key players to safeguard the hepatocyte and avoi...

journal_title：Current pharmaceutical biotechnology

authors： Wang R,Sheps JA,Ling V

更新日期：2011-04-01 00:00:00

abstract：:Lactobacilli are common microorganisms in diverse vegetables and meat products and several of these are also indigenous inhabitants in the gastro-intestinal (GI) tract of humans and animals where they are believed to have health promoting effects on the host. One of the highly appreciated probiotic effects is their ab...

journal_title：Current pharmaceutical biotechnology

authors： Diep DB,Mathiesen G,Eijsink VG,Nes IF

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:The work was performed to investigate the feasibility of preparing ocular inserts loaded with Poly-ε-Caprolactone (PCL) nanoparticles as a sustained ocular delivery system. METHODS:First, Atorvastatin Calcium-Poly-ε-Caprolactone (ATC-PCL) nanoparticles were prepared and characterized. Then, the optimized nanop...

journal_title：Current pharmaceutical biotechnology

authors： Girgis GNS

更新日期：2020-01-01 00:00:00

abstract：:Staphylococcus aureus is a leading causative agent in sepsis, endocarditis, and pneumonia. An emerging concept is that prognosis worsens when the infecting S. aureus strain has the capacity to not only colonize tissue as an extracellular pathogen, but to invade host cells and establish intracellular bacterial populati...

journal_title：Current pharmaceutical biotechnology

authors： Cordero D,Fullenkamp CR,Pelly RR,Reed KM,Caffo LM,Zahrt AN,Newman M,Komanapalli S,Niemeier EM,Bishop DL,Bruns HA,Haynes MK,Sklar LA,Sammelson RE,McDowell SA

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Tamarix Articulata (T. articulata), commonly known as Tamarisk or Athal in Arabic region, belongs to the Tamaricaece species. It is an important halophytic medicinal plant and a good source of polyphenolic phytochemical(s). In traditional medicines, T. articulata extract is commonly used, either singly or in...

journal_title：Current pharmaceutical biotechnology

authors： Alnuqaydan AM,Rah B

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Pentoxifylline (PTX) is a drug commonly used in the treatment of intermittent claudication. However, numerous research groups report that PTX also may potentially be used in the anticancer therapy following one of the main trends in the nowadays medicine - combined anticancer therapy. SCOPE OF REVIEW:The re...

journal_title：Current pharmaceutical biotechnology

authors： Golunski G,Woziwodzka A,Piosik J

更新日期：2018-01-01 00:00:00

abstract：:Platelet-rich plasma (PRP) is widely used to promote tissue repair and accelerate osteogenesis, but there is no agreement about its mechanism of action. We characterized the modulatory effect of PRP on the in vitro osteoblast model SaOS-2, by using cell motility/chemoattraction and osteogenesis/mineralization assays, ...

journal_title：Current pharmaceutical biotechnology

authors： Martinotti S,Mazzucco L,Balbo V,Patrone M,Mozzati M,Ranzato E,Burlando B

更新日期：2014-01-01 00:00:00

abstract：:Tryparedoxin peroxidase (TryP) is a key enzyme of the trypanothione-dependent metabolism for removal of oxidative stress in leishmania. These enzymes function as antioxidants through their peroxidase and peroxynitrite reductase activities. Inhibitors of this enzyme are presumed to be antilesihmania drugs and structura...

journal_title：Current pharmaceutical biotechnology

authors： Singh BK,Dubey VK

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Although the stability of proteins is of significance to maintain protein function for therapeutical applications, this remains a challenge. Herein, a general method of preserving protein stability and function was developed using gelatin films. METHODS:Enzymes immobilized onto films composed of gelatin and...

journal_title：Current pharmaceutical biotechnology

authors： Zhang L,Shen Y,Lu W,Guo L,Xiang M,Zhang D

更新日期：2020-01-01 00:00:00

abstract：:The number of diseases found to be associated with defects of the mitochondrial genome has grown significantly over the last decade. Despite major advances in understanding mtDNA defects at the genetic and biochemical level, there is no satisfactory treatment for the vast majority of patients available. This is largel...

journal_title：Current pharmaceutical biotechnology

authors： Weissig V,Torchilin VP

更新日期：2000-12-01 00:00:00

abstract：:Proliposomes are phospholipid based drug delivery systems that are finding important applications in the field of pharmaceutics. Proliposomes have been extensively studied as a potential carrier for oral delivery of drugs with poor bioavailability, but the mechanism of absorption and cellular uptake pathways has not y...

journal_title：Current pharmaceutical biotechnology

authors： Nekkanti V,Venkatesan N,Betageri GV

更新日期：2015-01-01 00:00:00

abstract：:Even though malnutrition is associated with an adverse prognosis after allogeneic stem cell transplantation, few studies have addressed the question what is the optimal nutritional support for these patients. There is a general agreement that the body weight, body mass index and nutritional intake can be used to guide...

journal_title：Current pharmaceutical biotechnology

authors： Tvedt TH,Reikvam H,Bruserud Ø

更新日期：2016-01-01 00:00:00

abstract：:Plants are rich in a wide variety of secondary metabolites with antimicrobial properties. Phytochemistry studies on the plants extracts in general, and on essential oils (EOs) in particular are focused on the isolation and identification of the components of complex mixtures, in order to determine structure - activity...

journal_title：Current pharmaceutical biotechnology

authors： Saviuc CM,Drumea V,Olariu L,Chifiriuc MC,Bezirtzoglou E,Lazăr V

更新日期：2015-01-01 00:00:00

abstract：:Nitric oxide (NO) participates in the control of the cardiovascular system where two constitutive isoforms of NO-synthase were discovered: endothelial and neuronal. Both isoforms were observed in various cells, however, endothelial NO-synthase is predominantly present in the endothelium. Injury of the endothelium dist...

journal_title：Current pharmaceutical biotechnology

authors： Cacanyiova S

更新日期：2011-09-01 00:00:00

abstract：:Pulmonary fibrosis is an unremitting degenerative lung disease that has an associated high mortality. The major pathological features include the growth of fibroblasts, emergence of myofibroblasts and their production of extracellular matrix that distorts the peripheral lung tissue and impairs respiratory function. Ef...

journal_title：Current pharmaceutical biotechnology

authors： Glasser SW,Senft AP

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Alternative medicine is available for those diseases which cannot be treated by conventional medicine. Ayurveda and herbal medicines are important alternative methods in which the treatment is done with extracts of different medicinal plants. This work is concerned with the evaluation of anti-stress bioactiv...

journal_title：Current pharmaceutical biotechnology

authors： Daddam JR,Sreenivasulu B,Umamahesh K,Peddanna K,Rao DM

更新日期：2020-01-01 00:00:00

abstract：:Excessive cell proliferation contributes to the pathobiology of human diseases with a high health and socio-economic impact, including cancer and vascular occlusive diseases (e. g., atherosclerosis, in-stent restenosis, transplant vasculopathy, and vessel bypass graft failure). Recent advances in the understanding of ...

journal_title：Current pharmaceutical biotechnology

authors： Ivorra C,Samyn H,Edo MD,Castro C,Sanz-González SM,Déez-Juan A,Andrés V

更新日期：2003-02-01 00:00:00

abstract：:The purpose of this review article is to describe the history of photodynamic therapy (PDT), its current medical applications, the mechanism of action, contraindications of the method, and different types of photosensitizers used. The second part of the article deals with applications for gastrointestinal diseases. Th...

journal_title：Current pharmaceutical biotechnology

authors： Wiedmann MW,Caca K

更新日期：2004-08-01 00:00:00

abstract：AIM OF THE STUDY:To assess tramadol and O-desmethyltramadol (M1) concentrations and their correlations with analgesia in patients with cancer pain. PATIENTS AND METHODS:Thirty opioid-naive patients with nociceptive pain intensity on VAS (visual analogue scale) > 40 received controlled-release tramadol as the first (15...

journal_title：Current pharmaceutical biotechnology

authors： Leppert W,Mikolajczak P

更新日期：2011-02-01 00:00:00

abstract：:Understanding and consequently treating neuropathic pain effectively is a challenge for modern medicine, as unlike inflammation, which can be controlled relatively well, chronic pain due to nerve injury is refractory to most current therapeutics. Here we define a target pathway for a new class of analgesics, tetrahydr...

journal_title：Current pharmaceutical biotechnology

authors： Latremoliere A,Costigan M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Citronella Oil (CO) was used by the Indian army as mosquito repellant to repel mosquitoes at the beginning of the 20th century and later in 1948, it was registered in the USA for commercial purposes. Due to its ecofriendly nature, CO possesses immense potential as a mosquito repellent. METHODS:Citronella oi...

journal_title：Current pharmaceutical biotechnology

authors： Sharma R,Kumar N,Singh SP,Kumar S,Rao R

更新日期：2020-01-01 00:00:00

abstract：:Herpes simplex virus (HSV) is a well-known vector that is often used for gene therapy to treat cancers. The most attractive feature of HSV is its ability to destroy tumors through a distinctive oncolytic mechanism where the virus can destroy cancer cells via cell lysis, a killing function that no anti-cancer drugs can...

journal_title：Current pharmaceutical biotechnology

authors： Wong J,Lee C,Zhang K,Rennie PS,Jia W

更新日期：2012-07-01 00:00:00

abstract：:More than 80% of all cancers are caused by solid malignancies. More than 90% of these tumours are of epithelial origin. The main principles in tumour treatment are surgery, radiotherapy, chemotherapy or combinations of these. Complete surgical removal of the tumour is the most effective therapy for solid malignancies....

journal_title：Current pharmaceutical biotechnology

authors： Mauerer R,Gruber R

更新日期：2012-06-01 00:00:00

abstract：:A novel steroidal oxime (SO) was synthesized using an economic method and then characterized by Fourier transform infrared (FTIR) and 1H nuclear magnetic resonance (NMR). When dispersed in pure water, SO can self-assemble into a nano-scale circular structure which was verified by dynamic light scattering (DLS) and tra...

journal_title：Current pharmaceutical biotechnology

authors： Chou TH,Chen CW

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Oxymatrine is one of the most promising alkaloids from Sophora flavescens for its excellent pharmacological effects. OBJECTIVE:The aim of this research is to assess the biopharmaceutical and pharmacokinetic activities of oxymatrine, and clarify its mechanisms of absorption and metabolism. METHODS:The biolo...

journal_title：Current pharmaceutical biotechnology

authors： Wang HQ,Chen FH,Wang L,Chi LQ,Wang GH

更新日期：2021-01-18 00:00:00