Abstract:
BACKGROUND:There are few studies of mortality amongst people who inject drugs (PWID) in Australia. In this study, we estimate mortality in a cohort of PWID in Melbourne and examine predictors of mortality including health service use, demographic characteristics, drug use and personal wellbeing. FINDINGS:We linked identifiers from the Melbourne injecting drug use cohort study (MIX; n = 655) to the National Death Index from 2008 to 2012 to estimate standardised mortality ratios (SMRs). Cox regression was used to examine the bivariate relationship between exposures determined at baseline and subsequent mortality. There were 24 (3.6%) deaths over the study period. The mortality rate in the cohort was 1.0 per 100 PY (95% CI 0.71-1.57), with an SMR of 17.3 (95 % CI 11.6-25.8). Baseline reports of four or more lifetime incarcerations (HR 3.65, 95 % CI 1.16-11.52), past month ambulance attendance (HR 4.43, 95 % CI 1.76-11.17), past month emergency department presentation (HR 3.44, 95 % CI 1.47-8.03) and past 6-month self-reported heroin overdose (HR 3.14, 95 % CI 1.24-7.96) were associated with increased mortality risk. CONCLUSIONS:Contact with emergency services, particularly for drug overdose, remains a lost opportunity to provide referrals for harm reduction and naloxone training programmes to PWID at greater risk of mortality.
journal_name
Harm Reduct Jjournal_title
Harm reduction journalauthors
Nambiar D,Agius PA,Stoové M,Hickman M,Dietze Pdoi
10.1186/s12954-015-0089-3subject
Has Abstractpub_date
2015-12-09 00:00:00pages
55issn
1477-7517pii
10.1186/s12954-015-0089-3journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Illicit drug users have a high prevalence of HCV and represent the majority of newly infected persons in the U.S. Despite the availability of effective HCV treatment, few drug users have been evaluated or treated for HCV. Racial and ethnic minorities have a higher incidence and prevalence of HCV and higher H...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-10-10
更新日期:2013-06-20 00:00:00
abstract:INTRODUCTION:The aim of this study is to identify the profiles of young people who use drugs (YPUD) and their exposure to HIV risks in the 3 main cities of Vietnam, Haiphong, Hanoi, and Ho Chi Minh City (HCMC), in order to design a community-based intervention to prevent HIV. METHODS:A survey using respondent-driven s...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00357-4
更新日期:2020-02-24 00:00:00
abstract:BACKGROUND:Patients with substance use disorders grow older thanks to effective treatments. Together with a high prevalence of comorbidities, psychological problems, and low social support, these patients are at high risk for medication non-adherence. Established treatment facilities face challenges to accommodate thes...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0182-x
更新日期:2017-08-16 00:00:00
abstract:BACKGROUND:In Cambodia, HIV prevalence among female entertainment and sex workers (FESW) is up to twenty times higher than in the general population. Use of amphetamine-type stimulants (ATS) has been associated with increased risk of HIV and other sexually transmitted infections in key populations, including FESW. Whil...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-015-0068-8
更新日期:2015-10-16 00:00:00
abstract:BACKGROUND:Treatment of hepatitis C (HCV) among people who inject drugs (PWID) is a critical component of efforts to eliminate viral hepatitis. A recent study found high HCV prevalence among PWID in two cities, Pretoria (84%) and Cape Town (44%). Very few (< 5%) HCV-infected individuals attended follow-up appointments....
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00382-3
更新日期:2020-06-10 00:00:00
abstract:BACKGROUND:Health services globally are struggling to manage the impact of COVID-19. The existing global disease burden related to opioid use is significant. Particularly challenging groups include older drug users who are more vulnerable to the effects of COVID-19. Increasing access to safe and effective opioid agonis...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00394-z
更新日期:2020-07-17 00:00:00
abstract:BACKGROUND:In 2016, the Australian federal government passed legislation enabling a range of cannabis-based products to be prescribed to patients by registered healthcare professionals. An online survey conducted immediately prior to these legislative changes found that the vast majority of respondents at the time were...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00377-0
更新日期:2020-06-08 00:00:00
abstract::With a worldwide prevalence of 15.4%, hepatitis C virus (HCV) has been estimated to be the most prevalent major infectious disease in prisons. The exceptionally high prevalence of HCV in prisons is attributable to common risk behaviors including sharing contaminated tattooing equipment and drug paraphernalia, as well ...
journal_title:Harm reduction journal
pub_type: 信件
doi:10.1186/s12954-020-00379-y
更新日期:2020-05-24 00:00:00
abstract:BACKGROUND:Due to the high prevalence of mental disorders among people with opioid use disorder, the objective of this study was to determine the association between concurrent mental disorders, mortality, morbidity, and continuous treatment retention for patients in opioid agonist treatment in Ontario, Canada. METHOD...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00396-x
更新日期:2020-07-23 00:00:00
abstract::Harm reduction is a controversial model for treating drug users, with little formal research available on its operation and effectiveness. In order to advance the field, we first conducted participatory research of harm reduction with 120 clients using nominal-group technique to develop culturally relevant outcomes to...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-1-7
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:The current illicit drug overdose crisis within North America and other countries requires expanded and new responses to address unpredictable and potentially lethal substances, including fentanyl analogues, in the unregulated drug market. Community-wide drug checking is being increasingly explored as one su...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00373-4
更新日期:2020-05-12 00:00:00
abstract:BACKGROUND:In response to the opioid epidemic, naloxone distribution programs aim to prevent overdose death by making naloxone available and training people to use it. Peers of individuals at risk of opioid overdose are well-positioned to administer naloxone and prevent overdose death. METHODS:We conducted key informa...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-019-0352-0
更新日期:2020-01-09 00:00:00
abstract:BACKGROUND:Stigma and discrimination may adversely affect the benefits of methadone maintenance treatment (MMT) for drug users, especially in disadvantaged settings. This study assessed stigma and discrimination against MMT patients in the mountainous and rural areas in Vietnam and explored their associated factors to ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-016-0127-9
更新日期:2017-01-06 00:00:00
abstract:OBJECTIVES:This study explored the relationship between product trials and consumer demand for alternative nicotine products (ANP). METHODS:An experimental auction was conducted with 258 adult smokers, wherein participants were randomly assigned to one of four experimental conditions. The participants received the opp...
journal_title:Harm reduction journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12954-015-0052-3
更新日期:2015-06-11 00:00:00
abstract:BACKGROUND:People who smoke crack cocaine experience a wide variety of health-related issues. However, public health programming designed for this population is limited, particularly in comparison with programming for people who inject drugs. Canadian best practice recommendations encourage needle and syringe programs ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0144-3
更新日期:2017-05-12 00:00:00
abstract:BACKGROUND:Only July 1, 2017, Nevada became the fifth US state to allow the legal sale of recreational cannabis products for adults ages of 21 and over. This study investigates young adults' cannabis-related attitudes, perceptions, and behaviors in a state where recreational and medical cannabis use was recently legali...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00442-8
更新日期:2020-11-26 00:00:00
abstract::This article examines harm reduction from a novel perspective. Its central thesis is that harm reduction is not only a social concept, but also a biological one. More specifically, evolution does not make moral distinctions in the selection process, but utilizes a cannabis-based approach to harm reduction in order to ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-2-17
更新日期:2005-09-22 00:00:00
abstract:BACKGROUND:This study aimed to investigate the development of opioid tolerance in patients receiving long-term methadone maintenance treatment (MMT). METHODS:A region-wide cross-sectional study was performed focusing on dosage and duration of treatment. Differences between racemic methadone and levomethadone were exam...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-016-0095-0
更新日期:2016-02-16 00:00:00
abstract:: For over 15 years the Australian Agency for International Development (AusAID) has been a leading donor for harm reduction projects in Southeast Asia. The recent AusAID-supported harm reduction projects of greatest significance have included the Asia Regional HIV/AIDS Project (AHRP), from 2002 until 2007,1 and the HI...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-9-23
更新日期:2012-07-09 00:00:00
abstract::Alcohol and other drug misuse are significant but neglected public health issues in conflict-affected populations. In this article, we review the literature on the challenges and strategies for implementing substance misuse treatment and prevention services in conflict and post-conflict settings in low- and middle-inc...
journal_title:Harm reduction journal
pub_type: 杂志文章,评审
doi:10.1186/s12954-018-0267-1
更新日期:2018-11-28 00:00:00
abstract::Needle exchange programs chase political as well as epidemiological dragons, carrying within them both implicit moral and political goals. In the exchange model of syringe distribution, injection drug users (IDUs) must provide used needles in order to receive new needles. Distribution and retrieval are co-existent in ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-7-1
更新日期:2010-01-04 00:00:00
abstract:BACKGROUND:Cannabis intoxication is related to a number of physical and mental health risks with ensuing social costs. However, little attention has been given to the investigation of possible pharmacological interactions in this condition. OBJECTIVE:To review the available scientific literature concerning pharmacolog...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-9-7
更新日期:2012-01-25 00:00:00
abstract:BACKGROUND:We have recently published some work on CEA levels in hookah (also called narghile, shisha elsewhere) and cigarette smokers. Hookah smokers had higher levels of CEA than non-smokers although mean levels were low compared to cigarette smokers. However some of them were also users of other tobacco products (ci...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-5-19
更新日期:2008-05-24 00:00:00
abstract:BACKGROUND:Recovery from substance use disorder (SUD) is often considered at odds with harm reduction strategies. More recently, harm reduction has been categorized as both a pathway to recovery and a series of services to reduce the harmful consequences of substance use. Peer recovery support services (PRSS) are effec...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-018-0258-2
更新日期:2018-10-22 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) infection is a global epidemic with an estimated 71 million people infected worldwide. People who inject drugs (PWID) are overrepresented in prison populations globally and have higher levels of HCV infection than the general population. Despite increased access to primary health care...
journal_title:Harm reduction journal
pub_type: 杂志文章,多中心研究
doi:10.1186/s12954-018-0269-z
更新日期:2018-12-11 00:00:00
abstract:BACKGROUND:Patients with opioid use disorder (OUD) frequently present to the emergency department for acute treatment of overdose and withdrawal. CASE PRESENTATION:A 29-year-old male presented to the emergency room after intravenous heroin use followed by accidental ingestion of naltrexone. He was treated with bupreno...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00417-9
更新日期:2020-10-07 00:00:00
abstract:BACKGROUND:The HIV epidemic among people who inject drugs (PWID) in Russia continues to spread. This exploratory study examines how HIV-prevention measures are perceived and experienced by PWID in the northwestern region of Russia. METHODS:Purposive sampling was used to obtain a variety of cases that could reflect pos...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0162-1
更新日期:2017-06-05 00:00:00
abstract:BACKGROUND:The hepatitis C virus (HCV) is a major cause of drug-related morbidity and mortality, with incidence data implicating a wide range of HCV transmission risk practices. The Blood-Borne Virus Transmission Risk Assessment Questionnaire (BBV-TRAQ) is a content valid instrument that comprehensively assesses HCV ri...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-5-12
更新日期:2008-04-23 00:00:00
abstract:: In their commentary, Dar and Frenk call into question the validity of all published data that describe the onset of nicotine addiction. They argue that the data that describe the early onset of nicotine addiction is so different from the conventional wisdom that it is irrelevant. In this rebuttal, the author argues t...
journal_title:Harm reduction journal
pub_type: 社论
doi:10.1186/1477-7517-7-26
更新日期:2010-11-04 00:00:00
abstract::Whilst unsupervised injectable methadone and diamorphine treatment has been part of the British treatment system for decades, the numbers receiving injectable opioid treatment (IOT) has been steadily diminishing in recent years. In contrast, there has been a recent expansion of supervised injectable diamorphine progra...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-3-28
更新日期:2006-09-27 00:00:00