Abstract:
BACKGROUND:Patients with opioid use disorder (OUD) frequently present to the emergency department for acute treatment of overdose and withdrawal. CASE PRESENTATION:A 29-year-old male presented to the emergency room after intravenous heroin use followed by accidental ingestion of naltrexone. He was treated with buprenorphine with significant improvement in his Clinical Opioid Withdrawal Score, from moderately severe to mild withdrawal symptoms within a few hours. CONCLUSION:Buprenorphine and minimal supportive care can be used to treat acute withdrawal precipitated by oral naltrexone in patients with OUD.
journal_name
Harm Reduct Jjournal_title
Harm reduction journalauthors
Szczesniak LM,Calleo VJ,Sullivan RWdoi
10.1186/s12954-020-00417-9subject
Has Abstractpub_date
2020-10-07 00:00:00pages
71issue
1issn
1477-7517pii
10.1186/s12954-020-00417-9journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Due to the high prevalence of mental disorders among people with opioid use disorder, the objective of this study was to determine the association between concurrent mental disorders, mortality, morbidity, and continuous treatment retention for patients in opioid agonist treatment in Ontario, Canada. METHOD...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00396-x
更新日期:2020-07-23 00:00:00
abstract:BACKGROUND:The hepatitis C virus (HCV) is a major cause of drug-related morbidity and mortality, with incidence data implicating a wide range of HCV transmission risk practices. The Blood-Borne Virus Transmission Risk Assessment Questionnaire (BBV-TRAQ) is a content valid instrument that comprehensively assesses HCV ri...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-5-12
更新日期:2008-04-23 00:00:00
abstract:BACKGROUND:In response to the opioid epidemic, naloxone distribution programs aim to prevent overdose death by making naloxone available and training people to use it. Peers of individuals at risk of opioid overdose are well-positioned to administer naloxone and prevent overdose death. METHODS:We conducted key informa...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-019-0352-0
更新日期:2020-01-09 00:00:00
abstract:BACKGROUND:Smoking is endemic amongst people accessing homeless services, and they are disproportionately affected by smoking-related diseases. This paper reports on the results of a 3-month small scale intervention which explored the efficacy, challenges and opportunities of using electronic nicotine delivery systems ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00406-y
更新日期:2020-10-12 00:00:00
abstract:OBJECTIVES:This study explored the relationship between product trials and consumer demand for alternative nicotine products (ANP). METHODS:An experimental auction was conducted with 258 adult smokers, wherein participants were randomly assigned to one of four experimental conditions. The participants received the opp...
journal_title:Harm reduction journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12954-015-0052-3
更新日期:2015-06-11 00:00:00
abstract:BACKGROUND:New, more effective and better-tolerated therapies for hepatitis C (HCV) have made the elimination of HCV a feasible objective. However, for this to be achieved, it is necessary to have a detailed understanding of HCV epidemiology in people who inject drugs (PWID). Respondent-driven sampling (RDS) can provid...
journal_title:Harm reduction journal
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12954-017-0172-z
更新日期:2017-07-11 00:00:00
abstract::Harm reduction is a controversial model for treating drug users, with little formal research available on its operation and effectiveness. In order to advance the field, we first conducted participatory research of harm reduction with 120 clients using nominal-group technique to develop culturally relevant outcomes to...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-1-7
更新日期:2004-06-01 00:00:00
abstract:: For over 15 years the Australian Agency for International Development (AusAID) has been a leading donor for harm reduction projects in Southeast Asia. The recent AusAID-supported harm reduction projects of greatest significance have included the Asia Regional HIV/AIDS Project (AHRP), from 2002 until 2007,1 and the HI...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-9-23
更新日期:2012-07-09 00:00:00
abstract:BACKGROUND:In 2016, the Australian federal government passed legislation enabling a range of cannabis-based products to be prescribed to patients by registered healthcare professionals. An online survey conducted immediately prior to these legislative changes found that the vast majority of respondents at the time were...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00377-0
更新日期:2020-06-08 00:00:00
abstract::BACKGROUND: Harm reduction is a relatively new and controversial model for treating drug users, with little formal research on its operation and effectiveness. In order to advance the study of harm reduction programs and our understanding of how drug users define their progress, qualitative research was conducted to d...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-1-8
更新日期:2004-08-26 00:00:00
abstract:BACKGROUND:This study aimed to investigate the development of opioid tolerance in patients receiving long-term methadone maintenance treatment (MMT). METHODS:A region-wide cross-sectional study was performed focusing on dosage and duration of treatment. Differences between racemic methadone and levomethadone were exam...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-016-0095-0
更新日期:2016-02-16 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) infection is a global epidemic with an estimated 71 million people infected worldwide. People who inject drugs (PWID) are overrepresented in prison populations globally and have higher levels of HCV infection than the general population. Despite increased access to primary health care...
journal_title:Harm reduction journal
pub_type: 杂志文章,多中心研究
doi:10.1186/s12954-018-0269-z
更新日期:2018-12-11 00:00:00
abstract:BACKGROUND:The HIV epidemic among people who inject drugs (PWID) in Russia continues to spread. This exploratory study examines how HIV-prevention measures are perceived and experienced by PWID in the northwestern region of Russia. METHODS:Purposive sampling was used to obtain a variety of cases that could reflect pos...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0162-1
更新日期:2017-06-05 00:00:00
abstract:OBJECTIVES:The COVID-19 pandemic led to the closure of the IDEA syringe services program medical student-run free clinic in Miami, Florida. In an effort to continue to serve the community of people who inject drugs and practice compassionate and non-judgmental care, the students transitioned the clinic to a model of Te...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00438-4
更新日期:2020-11-17 00:00:00
abstract:BACKGROUND:Options for opioid agonist therapy (OAT) are expanding with the development of prolonged-release (also known as extended-release) 1-week, 1-month, and 6-month formulations of buprenorphine. There is an assumption that patients will welcome these new treatments and medication adherence will correspondingly in...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-019-0296-4
更新日期:2019-04-03 00:00:00
abstract:BACKGROUND:Illicit drug users have a high prevalence of HCV and represent the majority of newly infected persons in the U.S. Despite the availability of effective HCV treatment, few drug users have been evaluated or treated for HCV. Racial and ethnic minorities have a higher incidence and prevalence of HCV and higher H...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-10-10
更新日期:2013-06-20 00:00:00
abstract:: In their commentary, Dar and Frenk call into question the validity of all published data that describe the onset of nicotine addiction. They argue that the data that describe the early onset of nicotine addiction is so different from the conventional wisdom that it is irrelevant. In this rebuttal, the author argues t...
journal_title:Harm reduction journal
pub_type: 社论
doi:10.1186/1477-7517-7-26
更新日期:2010-11-04 00:00:00
abstract:BACKGROUND:Ongoing legal and social discrimination, and stigmatization of people with lived experience of drug use (PWLE) continues to contribute to overdose-related deaths in Canada. The involvement of PWLE working in harm reduction services has proven effective in decreasing drug-related harms among PWLE; however, th...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00453-5
更新日期:2021-01-06 00:00:00
abstract:AIMS:To identify geographic "hotspots" for potential transmission of HIV and HCV and for drug overdose among persons who use heroin and cocaine in New York City and to examine historical continuities in problem drug use hotspots in the city. METHODS:A total of 2714 study participants were recruited among persons enter...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-019-0326-2
更新日期:2019-09-02 00:00:00
abstract:BACKGROUND:Health services globally are struggling to manage the impact of COVID-19. The existing global disease burden related to opioid use is significant. Particularly challenging groups include older drug users who are more vulnerable to the effects of COVID-19. Increasing access to safe and effective opioid agonis...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00394-z
更新日期:2020-07-17 00:00:00
abstract:INTRODUCTION:The aim of this study is to identify the profiles of young people who use drugs (YPUD) and their exposure to HIV risks in the 3 main cities of Vietnam, Haiphong, Hanoi, and Ho Chi Minh City (HCMC), in order to design a community-based intervention to prevent HIV. METHODS:A survey using respondent-driven s...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00357-4
更新日期:2020-02-24 00:00:00
abstract:BACKGROUND:Smoking cessation treatment service is concerned to be a critical element in methadone maintenance treatment (MMT) in order to diminish the effect of smoke on health outcomes. To implement the smoking cessation services in Vietnam, we examined the stages of change to quit and determined associated factors am...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-015-0085-7
更新日期:2015-10-30 00:00:00
abstract:BACKGROUND:To examine the predictors of continued drug- and sex-related HIV-risk behaviors among drug users in methadone maintenance therapy (MMT) programs in China. METHODS:We followed a sample of 5,035 drug users enrolled for the first time in MMT programs at baseline, 6 months, and 12 months utilizing a longitudina...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-10-23
更新日期:2013-10-10 00:00:00
abstract::With a worldwide prevalence of 15.4%, hepatitis C virus (HCV) has been estimated to be the most prevalent major infectious disease in prisons. The exceptionally high prevalence of HCV in prisons is attributable to common risk behaviors including sharing contaminated tattooing equipment and drug paraphernalia, as well ...
journal_title:Harm reduction journal
pub_type: 信件
doi:10.1186/s12954-020-00379-y
更新日期:2020-05-24 00:00:00
abstract:UNLABELLED:This qualitative study of travel-related risk behaviours of Slovene injection drug users was based on interviews with individuals enrolled in drug addiction treatment programmes run by three regional centres for prevention and treatment of drug addiction. The primary objective of the study was to analyse beh...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-8-8
更新日期:2011-04-17 00:00:00
abstract::Young people aged 15-24 years account for fifty percent of all new AIDS cases worldwide. Moreover, half of all new HIV infections are associated with injection drug use. The average age for initiation into injecting drug use is 20 years of age. This paper investigates whether HIV prevention programs have reduced risk ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-2-5
更新日期:2005-03-17 00:00:00
abstract:BACKGROUND:We utilized multiple recruitment approaches to recruit IDUs in a longitudinal cohort study to examine HIV incidence and behavior change pre- and post-introduction of comprehensive HIV prevention services. METHODS:IDUs were recruited through peer referral, targeted outreach by outreach workers (ORWs) and as ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-10-16
更新日期:2013-09-25 00:00:00
abstract::Whilst unsupervised injectable methadone and diamorphine treatment has been part of the British treatment system for decades, the numbers receiving injectable opioid treatment (IOT) has been steadily diminishing in recent years. In contrast, there has been a recent expansion of supervised injectable diamorphine progra...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-3-28
更新日期:2006-09-27 00:00:00
abstract:BACKGROUND:Condom provision is one of the most effective harm reduction interventions to control sexually transmitted infections (STIs) including HIV/AIDS and viral hepatitis in prisons. Yet, very few countries around the world provide prisoners with condoms. The present study aimed to elucidate principles of effective...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-021-00462-y
更新日期:2021-01-28 00:00:00
abstract:BACKGROUND:In some countries, "Big Events" like crises and transitions have been followed by large increases in drug use, drug injection and HIV/AIDS. Argentina experienced an economic crisis and political transition in 2001/2002 that affected how people use their time. This paper studies how time use changes between y...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-8-2
更新日期:2011-01-20 00:00:00