Abstract:
BACKGROUND:Illicit drug users have a high prevalence of HCV and represent the majority of newly infected persons in the U.S. Despite the availability of effective HCV treatment, few drug users have been evaluated or treated for HCV. Racial and ethnic minorities have a higher incidence and prevalence of HCV and higher HCV-related mortality. Factors contributing to poor engagement in care are incompletely understood. METHODS:Fourteen mixed-gender focus groups of either African American or Latino/a drug users (N = 95) discussed barriers to HCV testing and treatment. Themes were identified through content analysis of focus group discussions. RESULTS:Many drug users were tested for HCV in settings where they were receiving care. Outside of these settings, most were unaware of voluntary test sites. After testing HCV positive, drug users reported not receiving clear messages regarding the meaning of a positive HCV test, the impact of HCV infection, or appropriate next steps including HCV clinical evaluations. Many drug users perceived treatment as unimportant because they lacked symptoms, healthcare providers minimized the severity of the diagnosis, or providers did not recommend treatment. Mistrust of the motivations of healthcare providers was cited as a barrier to pursuing treatment. Social networks or social interactions were a source of HCV-related information and were influential in shaping drug users perceptions of treatment and its utility. CONCLUSION:Drug users perceived a paucity of settings for self-initiated HCV testing and poor provider-patient communication at test sites and during medical encounters. Notably, drug users reported having an unclear understanding about the meaning of a positive HCV test, the health implications of HCV infection, the importance of clinical evaluations and monitoring, and of treatment options for HCV. Efforts to improve the delivery of clinical messages about HCV infection for drug users at test settings and clinical encounters are needed.
journal_name
Harm Reduct Jjournal_title
Harm reduction journalauthors
Jordan AE,Masson CL,Mateu-Gelabert P,McKnight C,Pepper N,Bouche K,Guzman L,Kletter E,Seewald RM,Des-Jarlais DC,Sorensen JL,Perlman DCdoi
10.1186/1477-7517-10-10subject
Has Abstractpub_date
2013-06-20 00:00:00pages
10issn
1477-7517pii
1477-7517-10-10journal_volume
10pub_type
杂志文章abstract:BACKGROUND:People who smoke crack cocaine experience a wide variety of health-related issues. However, public health programming designed for this population is limited, particularly in comparison with programming for people who inject drugs. Canadian best practice recommendations encourage needle and syringe programs ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0144-3
更新日期:2017-05-12 00:00:00
abstract:BACKGROUND:There are few studies of mortality amongst people who inject drugs (PWID) in Australia. In this study, we estimate mortality in a cohort of PWID in Melbourne and examine predictors of mortality including health service use, demographic characteristics, drug use and personal wellbeing. FINDINGS:We linked ide...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-015-0089-3
更新日期:2015-12-09 00:00:00
abstract::Young people aged 15-24 years account for fifty percent of all new AIDS cases worldwide. Moreover, half of all new HIV infections are associated with injection drug use. The average age for initiation into injecting drug use is 20 years of age. This paper investigates whether HIV prevention programs have reduced risk ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-2-5
更新日期:2005-03-17 00:00:00
abstract:BACKGROUND:We utilized multiple recruitment approaches to recruit IDUs in a longitudinal cohort study to examine HIV incidence and behavior change pre- and post-introduction of comprehensive HIV prevention services. METHODS:IDUs were recruited through peer referral, targeted outreach by outreach workers (ORWs) and as ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-10-16
更新日期:2013-09-25 00:00:00
abstract::Whilst unsupervised injectable methadone and diamorphine treatment has been part of the British treatment system for decades, the numbers receiving injectable opioid treatment (IOT) has been steadily diminishing in recent years. In contrast, there has been a recent expansion of supervised injectable diamorphine progra...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-3-28
更新日期:2006-09-27 00:00:00
abstract:BACKGROUND:Greece has the highest smoking rates (in the 15-nation bloc) in Europe. The purpose of this study was to investigate Greek smokers' intention and appraisal of capability to quit employing the theoretical frameworks of Decisional Balance (DB) and Cognitive Dissonance (CD). METHODS:A cross-sectional study inc...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-3-13
更新日期:2006-03-29 00:00:00
abstract::A decade of research in Switzerland, The Netherlands, Germany, and Spain now constitutes a massive body of work supporting the use of heroin treatment for the most difficult patients addicted to opiates. These trials concur on this method's safety and efficacy and are now serving as a prelude to the institution of her...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-3-16
更新日期:2006-05-02 00:00:00
abstract:BACKGROUND:Prevalence of HIV infection among people who inject drugs (PWID) has been reported to be higher than that of the general population. The present study aimed to estimate the prevalence of HIV infection and associated risk factors among PWID in Dar es Salaam, Tanzania, following the introduction of a comprehen...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00364-5
更新日期:2020-03-24 00:00:00
abstract:BACKGROUND:Due to the high prevalence of mental disorders among people with opioid use disorder, the objective of this study was to determine the association between concurrent mental disorders, mortality, morbidity, and continuous treatment retention for patients in opioid agonist treatment in Ontario, Canada. METHOD...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00396-x
更新日期:2020-07-23 00:00:00
abstract:BACKGROUND:To understand the limits of HCV screening programs to reach all drug users (DUs). METHOD:The association of the recruitment of a representative sample of a population of DUs in a specific area with the use of a questionnaire that included 250 items allowed the use of uni- and multifactorial analysis to expl...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-018-0264-4
更新日期:2018-12-12 00:00:00
abstract:BACKGROUND:Patients with substance use disorders grow older thanks to effective treatments. Together with a high prevalence of comorbidities, psychological problems, and low social support, these patients are at high risk for medication non-adherence. Established treatment facilities face challenges to accommodate thes...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0182-x
更新日期:2017-08-16 00:00:00
abstract:BACKGROUND:Cannabis intoxication is related to a number of physical and mental health risks with ensuing social costs. However, little attention has been given to the investigation of possible pharmacological interactions in this condition. OBJECTIVE:To review the available scientific literature concerning pharmacolog...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-9-7
更新日期:2012-01-25 00:00:00
abstract:BACKGROUND:The current illicit drug overdose crisis within North America and other countries requires expanded and new responses to address unpredictable and potentially lethal substances, including fentanyl analogues, in the unregulated drug market. Community-wide drug checking is being increasingly explored as one su...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-020-00373-4
更新日期:2020-05-12 00:00:00
abstract:BACKGROUND:This study aimed to investigate the development of opioid tolerance in patients receiving long-term methadone maintenance treatment (MMT). METHODS:A region-wide cross-sectional study was performed focusing on dosage and duration of treatment. Differences between racemic methadone and levomethadone were exam...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-016-0095-0
更新日期:2016-02-16 00:00:00
abstract:BACKGROUND:New, more effective and better-tolerated therapies for hepatitis C (HCV) have made the elimination of HCV a feasible objective. However, for this to be achieved, it is necessary to have a detailed understanding of HCV epidemiology in people who inject drugs (PWID). Respondent-driven sampling (RDS) can provid...
journal_title:Harm reduction journal
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12954-017-0172-z
更新日期:2017-07-11 00:00:00
abstract:BACKGROUND:The HIV epidemic among people who inject drugs (PWID) in Russia continues to spread. This exploratory study examines how HIV-prevention measures are perceived and experienced by PWID in the northwestern region of Russia. METHODS:Purposive sampling was used to obtain a variety of cases that could reflect pos...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0162-1
更新日期:2017-06-05 00:00:00
abstract::Alcohol and other drug misuse are significant but neglected public health issues in conflict-affected populations. In this article, we review the literature on the challenges and strategies for implementing substance misuse treatment and prevention services in conflict and post-conflict settings in low- and middle-inc...
journal_title:Harm reduction journal
pub_type: 杂志文章,评审
doi:10.1186/s12954-018-0267-1
更新日期:2018-11-28 00:00:00
abstract:BACKGROUND:We have recently published some work on CEA levels in hookah (also called narghile, shisha elsewhere) and cigarette smokers. Hookah smokers had higher levels of CEA than non-smokers although mean levels were low compared to cigarette smokers. However some of them were also users of other tobacco products (ci...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-5-19
更新日期:2008-05-24 00:00:00
abstract:OBJECTIVES:This study explored the relationship between product trials and consumer demand for alternative nicotine products (ANP). METHODS:An experimental auction was conducted with 258 adult smokers, wherein participants were randomly assigned to one of four experimental conditions. The participants received the opp...
journal_title:Harm reduction journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12954-015-0052-3
更新日期:2015-06-11 00:00:00
abstract:BACKGROUND:During the 1990s, the New York Police Department (NYPD) greatly expanded arrests for smoking marijuana in public view (MPV). By 2000, MPV accounted for 15% of all arrests. The NYPD's supporters report this arrest activity is just part of quality-of-life (QOL) policing, which seeks to promote order in public ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-3-22
更新日期:2006-08-04 00:00:00
abstract::The findings of our research show that while police play multiple roles in the fight against drug-related crime, they often perceived their tasks - especially preventing and controlling drug use on the one hand, and supporting harm reduction on the other - as contradictory, and this creates tensions in their work and ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-9-25
更新日期:2012-07-09 00:00:00
abstract:BACKGROUND:Recovery from substance use disorder (SUD) is often considered at odds with harm reduction strategies. More recently, harm reduction has been categorized as both a pathway to recovery and a series of services to reduce the harmful consequences of substance use. Peer recovery support services (PRSS) are effec...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-018-0258-2
更新日期:2018-10-22 00:00:00
abstract:AIMS:To identify geographic "hotspots" for potential transmission of HIV and HCV and for drug overdose among persons who use heroin and cocaine in New York City and to examine historical continuities in problem drug use hotspots in the city. METHODS:A total of 2714 study participants were recruited among persons enter...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-019-0326-2
更新日期:2019-09-02 00:00:00
abstract:BACKGROUND:In some countries, "Big Events" like crises and transitions have been followed by large increases in drug use, drug injection and HIV/AIDS. Argentina experienced an economic crisis and political transition in 2001/2002 that affected how people use their time. This paper studies how time use changes between y...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-8-2
更新日期:2011-01-20 00:00:00
abstract:BACKGROUND:Community pharmacies are important for health access by rural populations and those who do not have optimum access to the health system, because they provide myriad health services and are found in most communities. This includes the sale of non-prescription syringes, a practice that is legal in the USA in a...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-019-0327-1
更新日期:2019-09-18 00:00:00
abstract:BACKGROUND:Gambling has quickly emerged as an important global public health issue. With new technologies used to develop high intensity gambling products and promotions aimed at driving consumption, public health organisations and researchers, community groups, and politicians have argued for a range of regulatory and...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/s12954-017-0173-y
更新日期:2017-07-25 00:00:00
abstract:: In their commentary, Dar and Frenk call into question the validity of all published data that describe the onset of nicotine addiction. They argue that the data that describe the early onset of nicotine addiction is so different from the conventional wisdom that it is irrelevant. In this rebuttal, the author argues t...
journal_title:Harm reduction journal
pub_type: 社论
doi:10.1186/1477-7517-7-26
更新日期:2010-11-04 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) infection is a global epidemic with an estimated 71 million people infected worldwide. People who inject drugs (PWID) are overrepresented in prison populations globally and have higher levels of HCV infection than the general population. Despite increased access to primary health care...
journal_title:Harm reduction journal
pub_type: 杂志文章,多中心研究
doi:10.1186/s12954-018-0269-z
更新日期:2018-12-11 00:00:00
abstract::With a worldwide prevalence of 15.4%, hepatitis C virus (HCV) has been estimated to be the most prevalent major infectious disease in prisons. The exceptionally high prevalence of HCV in prisons is attributable to common risk behaviors including sharing contaminated tattooing equipment and drug paraphernalia, as well ...
journal_title:Harm reduction journal
pub_type: 信件
doi:10.1186/s12954-020-00379-y
更新日期:2020-05-24 00:00:00
abstract::This article examines harm reduction from a novel perspective. Its central thesis is that harm reduction is not only a social concept, but also a biological one. More specifically, evolution does not make moral distinctions in the selection process, but utilizes a cannabis-based approach to harm reduction in order to ...
journal_title:Harm reduction journal
pub_type: 杂志文章
doi:10.1186/1477-7517-2-17
更新日期:2005-09-22 00:00:00