Assessing risk/benefit for trials using preclinical evidence: a proposal.

abstract：:Article 3.4 of EC directive 89/381 requires member states to take "all necessary measures to promote Community self-sufficiency in human blood or human plasma" and, for this purpose, to "encourage the voluntary unpaid donation of blood and plasma". This paper presents an ethical case in support of the policy of volunt...

journal_title：Journal of medical ethics

authors： Keown J

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVES:Potentially life-shortening medical end-of-life practices (end-of-life decisions (ELDs)) remain subject to conceptual vagueness. This study evaluates how physicians label these practices by examining which of their own practices (described according to the precise act, the intention, the presence of an expli...

journal_title：Journal of medical ethics

authors： Deyaert J,Chambaere K,Cohen J,Roelands M,Deliens L

更新日期：2014-07-01 00:00:00

abstract：:This paper relates two experiences of teaching medical ethics, the first to a small group of clinical medical students, the second to a larger group of GP trainees. :Boyd, a theologian who is Scottish Director of the Institute of Medical Ethics, comments on a day he spent teaching two ethics sessions, one to a group ...

journal_title：Journal of medical ethics

authors： Boyd K

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:According to the Declaration of Helsinki, patients who take part in a clinical trial must be adequately informed about the trial's aims, methods, expected benefits, and potential risks. The declaration does not, however, elaborate on what "adequately informed" might amount to, in practice. Medical researcher...

journal_title：Journal of medical ethics

authors： Ferguson PR

更新日期：2002-02-01 00:00:00

abstract：:Some disability rights advocates criticise prenatal testing and selective abortion on the grounds that these practices express negative attitudes towards existing persons with disabilities. Disability rights advocates also commonly criticise and oppose physician-assisted suicide (PAS) and euthanasia on the same ground...

journal_title：Journal of medical ethics

authors： Reed P

更新日期：2020-08-01 00:00:00

abstract：:In popular lay discourse, objections to human biological enhancement technologies are sometimes expressed in terms of the charge that they are unnatural. This paper critiques the literal claim that seems to be presented here, namely that such technologies are in some ordinary sense 'unnatural' and that it follows from...

journal_title：Journal of medical ethics

authors： Miller PR

更新日期：2019-02-01 00:00:00

abstract：:Literary accounts of traumatic events can be more informative and insightful than personal testimonials. In particular, reference to works of literature can give us a more vivid sense of what it is like to receive a devastating diagnosis. In turn this can lead us to question some common assumptions about the nature of...

journal_title：Journal of medical ethics

authors： Spriggs M

更新日期：1998-04-01 00:00:00

abstract：:This paper argues that the HFEA's recent report on sex selection abdicates its responsibility to give its own authentic advice on the matters within its remit, that it accepts arguments and conclusions that are implausible on the face of it and where they depend on empirical claims, produces no empirical evidence what...

journal_title：Journal of medical ethics

authors： Harris J

更新日期：2005-05-01 00:00:00

abstract：:Clinicians' work depends on sincere and complete disclosures from their patients; they honour this candidness by confidentially safeguarding the information received. Breaching confidentiality causes harms that are not commensurable with the possible benefits gained. Limitations or exceptions put on confidentiality wo...

journal_title：Journal of medical ethics

authors： Kottow MH

更新日期：1986-09-01 00:00:00

abstract：:Physician-written "do not resuscitate" DNR orders elicit negative reactions from stakeholders that may decrease appropriate end-of-life care. The semantic significance of the phrase has led to a proposed replacement of DNR with "allow natural death" (AND). Prior to this investigation, no scientific papers address the ...

journal_title：Journal of medical ethics

authors： Venneman SS,Narnor-Harris P,Perish M,Hamilton M

更新日期：2008-01-01 00:00:00

abstract：:The objective of this paper is to stimulate academic debate on embryo and fetal research from the perspective of the drafting of a protocol to the European Convention on Biomedicine. The Steering Committee on Bioethics of the Council of Europe was mandated to draw up such a protocol and for this purpose organised an i...

journal_title：Journal of medical ethics

authors： Byk JC

更新日期：1997-02-01 00:00:00

abstract：:With the recent developments in the Human Genome Mapping Project and the new technologies that are developing from it there is a renewal of concern about eugenic applications. Francis Galton (b1822, d1911), who developed the subject of eugenics, suggested that the ancient Greeks had contributed very little to social t...

journal_title：Journal of medical ethics

authors： Galton DJ

更新日期：1998-08-01 00:00:00

abstract：:A new human life comes into being not when there is mere cellular life in a human embryo, but when the newly developing body organs and systems begin to function as a whole, the author argues. This is symmetrical with the dealth of an existing human life, which occurs when its organs and systems have permanently cease...

journal_title：Journal of medical ethics

authors： Shea MC

更新日期：1985-12-01 00:00:00

abstract：:It is a common feature of debates on the regulation of reproductive medicine to find law portrayed as a crude form of intervention consisting in the imposition of inflexible rules on doctors and medical researchers. This paper argues that this view must be replaced by a more accurate assessment of the law's potential ...

journal_title：Journal of medical ethics

authors： Jabbari D

更新日期：1990-03-01 00:00:00

abstract：:Ancell and Sinnott-Armstrong argue that medical providers possess wide freedoms to determine the scope of their practice, and therefore, prohibiting almost any conscientious objections is a bad idea. They maintain that we could create an acceptable system on the whole which even grants accommodations to discriminatory...

journal_title：Journal of medical ethics

authors： Card RF

更新日期：2019-03-01 00:00:00

abstract：:In this article, we discuss the ethical dimensions for the prescribing behaviours of opioids for a chronic pain patient, a scenario commonly witnessed by many physicians. The opioid epidemic in the USA and Canada is well known, existing since the late 1990s, and individuals are suffering and dying as a result of the e...

journal_title：Journal of medical ethics

authors： Yan E,Kuo DJ

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Consultation methods differ between medical practitioners depending on the individual setting. However, the central tenet to the doctor-patient relationship is the issue of confidentiality. This prospective survey highlights patient attitudes towards consultation methods in the setting of an ophthalmic out...

journal_title：Journal of medical ethics

authors： Aslam SA,Colapinto P,Sheth HG,Jain R

更新日期：2007-03-01 00:00:00

abstract：:This paper is a response to Dr Shinebourne's response to my recent paper assessing the relative merits of the Staffordshire Protocol on covert video surveillance. Dr Shinebourne does not take the opportunity to rebut the criticisms made of the text of the protocol. It is further suggested that judicial oversight of th...

journal_title：Journal of medical ethics

authors： Thomas T

更新日期：1996-12-01 00:00:00

abstract：:Because of cultural differences between East and West, any attempt at outright adaptation of Western ideas in Asia will undoubtedly encounter problems, if not rejection. Transferring an idea from one place to another is just like transplanting an organ from a donor to a recipient--rejection is to be expected. Human cu...

journal_title：Journal of medical ethics

authors： Tai MC,Lin CS

更新日期：2001-02-01 00:00:00

abstract：:This article tackles the current deficit in the supply of cadaveric organs by addressing the family veto in organ donation. The authors believe that the family veto matters-ethically as well as practically-and that policies that completely disregard the views of the family in this decision are likely to be counterprod...

journal_title：Journal of medical ethics

authors： De Wispelaere J,Stirton L

更新日期：2010-03-01 00:00:00

abstract：:Dr. Bernstein suggests that anti-vivisectionists should be able to fill in a directive requesting that they receive no medical treatment developed through work on animals. It is replied that this would only be reasonable if research not using animals had long been funded as adequately and its results were currently av...

journal_title：Journal of medical ethics

authors： Sprigge T

更新日期：1996-10-01 00:00:00

abstract：:This article reports on moral problems that were raised by medical students as the basis for an ethical case-conference in an obstetrics and gynaecology clerkship. After introducing the issue of teaching clinical ethics, the method of our case-conference is explained. Next, the variety of topics and related moral prob...

journal_title：Journal of medical ethics

authors： Olthuis G,Dukel L

更新日期：2008-09-01 00:00:00

abstract：:Antimicrobial therapy is a cornerstone of therapy in critically ill patients; however, the wide use of antibiotics has resulted in increased antimicrobial resistance and outbreaks of resistant disease. To counter this, many hospitals have instituted antimicrobial stewardship programmes as a way to reduce the inappropr...

journal_title：Journal of medical ethics

authors： Oczkowski S

更新日期：2017-10-01 00:00:00

abstract：:The feasibility of a common European code of medical ethics is discussed, with consideration and evaluation of the difficulties such a project is going to face, from both the legal and ethical points of view. On the one hand, the analysis will underline the limits of a common European code of medical ethics as an inst...

journal_title：Journal of medical ethics

authors： Patuzzo S,Pulice E

更新日期：2017-01-01 00:00:00

abstract：:As the demand for healthcare rises, so does the need for priority setting in healthcare. In this paper, I consider a prominent priority-setting principle: proportional shortfall. My purpose is to argue that proportional shortfall, as a principle, should not be adopted. My key criticism is that proportional shortfall f...

journal_title：Journal of medical ethics

authors： Altmann S

更新日期：2018-05-01 00:00:00

abstract：:Technological advances in genetic testing have enabled prospective parents to learn about their risk of passing a genetic condition to their future children. One option for those who want to ensure that their biological children do not inherit a genetic condition is to create embryos through in vitro fertilisation (IV...

journal_title：Journal of medical ethics

authors： Kilbride MK

更新日期：2020-08-19 00:00:00

abstract：:In healthcare, a tension sometimes arises between the injunction to do as much good as possible with scarce resources and the injunction to rescue identifiable individuals in immediate peril, regardless of cost (the "Rule of Rescue"). This tension can generate serious ethical and political difficulties for public poli...

journal_title：Journal of medical ethics

authors： Cookson R,McCabe C,Tsuchiya A

更新日期：2008-07-01 00:00:00

abstract：:In an influential essay entitled Why abortion is wrong, Donald Marquis argues that killing actual persons is wrong because it unjustly deprives victims of their future; that the fetus has a future similar in morally relevant respects to the future lost by competent adult homicide victims, and that, as consequence, abo...

journal_title：Journal of medical ethics

authors： Brown MT

更新日期：2000-04-01 00:00:00

abstract：:We propose a principle of sustainability to complement established principles used for justifying healthcare resource allocation. We argue that the application of established principles of equal treatment, need, prognosis and cost-effectiveness gives rise to what we call negative dynamics: a gradual depletion of the v...

journal_title：Journal of medical ethics

authors： Munthe C,Fumagalli D,Malmqvist E

更新日期：2021-02-01 00:00:00

abstract：:In his paper "Scientific research is a moral duty", John Harris argues that individuals have a moral duty to participate in biomedical research by volunteering as research subjects. He supports his claim with reference to what he calls the principle of beneficence as embodied in the "rule of rescue" (the moral obligat...

journal_title：Journal of medical ethics

authors： Shapshay S,Pimple KD

更新日期：2007-07-01 00:00:00