Abstract：
:Prostate cancer is a slow progressing cancer that affects millions of men in the US. Due to uncertainties in outcomes and treatment complications, it is important that patients engage in informed decision making to choose the "optimal treatment". Patient centered care that encompasses informed decision-making can improve treatment choice and quality of care. Thus, assessing patient treatment preferences is critical for developing an effective decision support system. The objective of this patient-centered randomized clinical trial was to study the comparative effectiveness of a conjoint analysis intervention compared to usual care in improving subjective and objective outcomes in prostate cancer patients. We identified preferred attributes of alternative prostate cancer treatments that will aid in evaluating attributes of treatment options. In this two-phase study, in Phase 1 we used mixed methods to develop an adaptive conjoint task instrument. The conjoint task required the patients to trade-off attributes associated with treatments by assessing their relative importance. Phase 2 consisted of a randomized controlled trial of men with localized prostate cancer. We analyzed the effect of conjoint task intervention on the association between preferences, treatment and objective and subjective outcomes. Our conjoint task instrument can lead to a values-based patient-centered decision aid tool and help tailor treatment decision making to the values of prostate cancer patients. This will ultimately improve clinical decision making, clinical policy process, enhance patient centered care and improve prostate cancer outcomes.
journal_name
Contemp Clin Trialsjournal_title
Contemporary clinical trialsauthors
Jayadevappa R,Chhatre S,Gallo JJ,Wittink M,Morales KH,Bruce Malkowicz S,Lee D,Guzzo T,Caruso A,Van Arsdalen K,Wein AJ,Sanford Schwartz Jdoi
10.1016/j.cct.2015.09.024subject
Has Abstractpub_date
2015-11-01 00:00:00pages
296-301issue
Pt Beissn
1551-7144issn
1559-2030pii
S1551-7144(15)30099-9journal_volume
45pub_type
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