Abstract：
:Plant based products laced with synthetic cannabinoids have become popular substances of abuse over the last decade. Quantitative analysis for synthetic cannabinoid content in the laced materials is necessary for health hazard assessments addressing overall exposure and toxicity when the products are smoked. A validated, broadly applicable HPLC-UV method for the determination of synthetic cannabinoids in plant materials is presented, using acetonitrile extraction and separation on a commercial phenylhexyl stationary phase. UV detection provides excellent sensitivity with limits of quantitation (LOQs) less than 10 μg/g for many cannabinoids. The method was validated for several structural classes (dibenzopyrans, cyclohexylphenols, naphthoylindoles, benzoylindoles, phenylacetylindoles, tetramethylcyclopropylindoles) based on spike recovery experiments in multiple plant materials over a wide cannabinoid contents range (0.1-81 mg/g). Average recovery across 32 cannabinoids was 94% for marshmallow leaf, 95% for damiana leaf, and 92% for mullein leaf. The method was applied to a series of case-related products with determined amounts ranging from 0.2 to >100 mg/g.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Ciolino LAdoi
10.1111/1556-4029.12795subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1171-81issue
5eissn
0022-1198issn
1556-4029journal_volume
60pub_type
杂志文章abstract：:Accurate quantification of DNA samples is an important step in obtaining accurate and reproducible short tandem repeat (STR) profiles. Quantitative real-time-PCR has improved the speed and accuracy of DNA quantification over earlier methods, albeit at significantly greater cost per reaction. Here, the performance of r...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2007.00525.x
更新日期：2007-09-01 00:00:00
abstract：:A case of multiple animal bite wounds is presented along with the techniques used to apprehend the culprits. The victim was a 13 month-old black female who had in excess of 80 puncture wounds. Initially the wounds were thought to be caused by a mechanical instrument but, after an autopsy, were determined to be caused ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1975-04-01 00:00:00
abstract：:A 48-year-old woman was found dead on a chair in her living room. She had received dialysis every day because of chronic renal failure for the past 15 years. On a table beside her, there was a mirror and 10-mL syringe on a napkin. A stopper was out of place in a portion of a three-way blood access tube established in ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01471.x
更新日期：2010-11-01 00:00:00
abstract：:The association between perpetration of sexual abuse and the offender's own victimization as a child has been well documented in the literature. Various researchers have examined this relationship by assessing the exclusiveness of the sexual abuser's behavior, the gender of his victims and the gender of his own childh...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:New procedures, tailored after such court decisions as Rogers v. Commissioner of the Department of Mental Health, have restricted the doctor's ability to treat psychiatric inpatients with psychotropic medication and have increased the protection of a competent patient's right to refuse. This study investigates how the...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Knowledge concerning the distribution of methadone in postmortem human tissue and the effect of postmortem redistribution on methadone is today limited making the choice of a suitable substitute for femoral blood difficult when this is not available. Cardiac blood, femoral blood, muscle, and brain tissue concentration...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12627
更新日期：2015-01-01 00:00:00
abstract：:A Scientific Working Group on DNA Analysis Methods (SWGDAM) developmental validation study was carried out on two Y-STR multiplex systems (MPI and MPII) that collectively permit the co-amplification of 19 Y-STR markers, including DYS393, DYS392, DYS391, DYS389I, DYS389II, Y-GATA-A7.2 (DYS461), DYS438, DYS385a and DYS3...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:Separation of male and female soft tissue depths into discrete groups for craniofacial identification implies that males and females differ enough from each other, with respect to this application, for this distinction to be useful. In this study, previously published soft tissue depth data were analyzed for sex separ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:Age estimation methods are often based on the age-related morphological changes of the auricular surface and the pubic bone. In this study, a mathematical approach to quantify these changes has been tested analyzing the curvature variation on 3D models from CT and laser scans. The sample consisted of the 24 Suchey-Bro...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12689
更新日期：2015-05-01 00:00:00
abstract：:The purpose of these studies was to evaluate the performance characteristics of the Cozart Microplate Enzyme Immunoassay (EIA) for the determination of methadone in oral fluid from patients in a drug misuse treatment program. Oral fluid specimens were collected using the Cozart RapiScan Collection system from 198 dono...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
abstract：:The aims of this study were to enable geometric morphometric sex classification using tibial proximal and distal sexual dimorphism and to evaluate the secular trend of tibial shape/form from the early 20th century to the present day. The study samples consisted of 61 adult tibias from an early 20th-century Czech popul...
journal_title：Journal of forensic sciences
pub_type： 历史文章,杂志文章
doi：10.1111/1556-4029.12641
更新日期：2015-01-01 00:00:00
abstract：:Sudden unexplained nocturnal death syndrome (SUNDS) is widely considered to be related to hereditary fatal arrhythmias. Hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) channels are widely distributed in sinus myocytes and play a profound role in generating pacemaker electro-activity in cardiomyocy...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13958
更新日期：2019-07-01 00:00:00
abstract：:Graphic exemplars of cranial sex and ancestry are essential to forensic anthropology for standardizing casework, training analysts, and communicating group trends. To date, graphic exemplars have comprised hand-drawn sketches, or photographs of individual specimens, which risks bias/subjectivity. Here, we performed qu...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13314
更新日期：2017-05-01 00:00:00
abstract：:Hungarian population data for the loci LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQA1, and D1S80 were generated. The genotype frequency distributions for the loci do not deviate from Hardy Weinberg expectations. Furthermore, there was little evidence for departures from expectations of independence between the loci. Using a tes...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:In this work, we present a measuring methodology for long bones of the limbs (humerus, femur, and tibia) of human corpses. Measurements of cadaveric height and long bone lengths were conducted on 72 corpses (20 females and 52 males) from the School of Medicine at the National Autonomous University of Mexico. Additiona...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12459
更新日期：2014-09-01 00:00:00
abstract：:The allele frequency distributions of three STR loci amplified by PCR have been studied in four Israeli communities: Ashkenazi Jews and three non-Ashkenazi groups, namely Moroccan, Yemenite, and Ethiopian Jews. The loci analyzed were CSF1PO, TPOX, and HUMTHO1. The typing was performed in sequencing polyacrylamide gels...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:This study examined the effects of fire on the features associated with saw marks in bone. Both class and individual characteristics were examined using stereomicroscopy and scanning electron microscopy (SEM). Twenty-four semifleshed Sus scrofa L. tibiae were sawed into three sections with the middle section having de...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12580
更新日期：2015-01-01 00:00:00
abstract：:The analysis of bloodstain patterns can assist investigators in understanding the circumstances surrounding a violent crime. Bloodstains are routinely subjected to pattern analysis, which is inherently dependent upon the ability of the examiner to locate and visualize bloodstain patterns on items of evidence. Often, t...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2012.02171.x
更新日期：2012-11-01 00:00:00
abstract：:A human skull identified as that of a 16-year-old female who had been reported missing about 3 years before the discovery of the specimen displayed evidence for the asymmetrical remodelling of bilateral neurosurgical burr holes. While one of the holes retained its original size and shape, gross evidence for the contra...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:Suicide by inhalation of carbon monoxide produced by mixing formic acid and sulfuric acid within a confined space is a rare method of suicide. This method is similar to the so-called "detergent suicide" method where an acid-based detergent is mixed with a sulfur source to produce hydrogen sulfide. Both methods produce...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12297
更新日期：2014-01-01 00:00:00
abstract：:Traditionally, the manner of death in most hospital autopsy cases is natural, in which death is due to the natural course of disease or reasonably anticipated outcomes of medical interventions. Some cases fall into a potential gray zone between natural and accident, including rare or unanticipated outcomes of medical ...
journal_title：Journal of forensic sciences
pub_type：
doi：10.1111/1556-4029.13844
更新日期：2019-01-01 00:00:00
abstract：:Trace metal ratios in human bones were examined to determine if there were ratios that were sufficiently consistent within an individual yet varying sufficiently from the bones of another individual so that bones in a mixed grave could be reassembled. The concentrations of 21 elements sampled at 54 places on 30 human ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1986-10-01 00:00:00
abstract：:Previously reported cases of suicide by intravenous barbiturates, as well as two other unusual cases [5,6], are compared in Table 2. All decedents were either medical or paramedical personnel and familiar with the drugs and the routes of administration used for their suicides. Lethal is used in veterinary euthanasia a...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1979-10-01 00:00:00
abstract：:The authors present the medico-legal investigations and identification after the aircrash of the Airbus A320 upon the Mount Sainte-Odile (France). The identification team comprising investigators from the gendarmerie, forensic pathologists, odontologists, and scientists of the Institute from Legal Medecine rapidly ret...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:The acetabulum/pubis index was tested on American Eskimo and Indian samples of innominate bones to which sex had been assigned by visual inspection. The index alone sexed 91 and 89% of the Eskimo and Indian samples, respectively. Subsequent sorting of misclassified specimens with femur head diameter resulted in 96 and...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：:In this report, the authors present a case of unusual, accidental methadone intoxication in a 40-year-old man, who had inhaled methadone powder. The drug dealer was a pharmacy technician; methadone had been stolen from a pharmacy and sold as cocaine. After having inhaled methadone powder, he suffered cardiopulmonary a...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2011.01730.x
更新日期：2011-07-01 00:00:00
abstract：:It is thought that, in a consignment of discrete units, a certain proportion of the units contain illegal material. A sample of the consignment is to be inspected. Various methods for the determination of the sample size are compared. The consignment will be considered as a random sample from some super-population of ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：:Unclaimed dead are deceased persons with no known next of kin (NoK) or NoK was located but did not claim the deceased. Unclaimed dead in Marion County, Indiana, 2004-2011, are examined. Comparisons are provided of the unclaimed to the claimed dead population and county death patterns. Race, gender, marital status, age...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12973
更新日期：2016-01-01 00:00:00
abstract：:Skeletal remains were discovered in an unused cistern near the Omaha, Nebraska airport and were positively identified through comparison of antemortem and postmortem dental radiographs. Although nearly nine years had elapsed between death and discovery, the bones and teeth revealed evidence of the application of a cor...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:A case is presented where phentermine, a sympathomimetic amine used as an anorectic drug, is believed to have significantly contributed to the death of an individual in whom other drugs were also found. Blood, urine, and tissue concentrations of phentermine are reported and compared to other cases in the literature. ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
