Abstract:
:Treatments targeting the Ebola virus may eventually be shown to work, but they will not have an impact on overall Ebola mortality in West Africa. Endothelial dysfunction is responsible for the fluid and electrolyte imbalances seen in Ebola patients. Because inexpensive generic statins and angiotensin receptor blockers restore endothelial barrier integrity, they can be used to treat the host response in these patients. In Sierra Leone, approximately 100 Ebola patients were treated with this combination, and reports indicate that survival was greatly improved.
journal_name
mBiojournal_title
mBioauthors
Fedson DS,Jacobson JR,Rordam OM,Opal SMdoi
10.1128/mBio.00716-15subject
Has Abstractpub_date
2015-06-23 00:00:00pages
e00716issue
3issn
2150-7511pii
mBio.00716-15journal_volume
6pub_type
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