Cutaneous Phaeohyphomycosis Caused by Exophiala attenuata in a Domestic Cat.

Abstract:

:A 7-year-old female-spayed, domestic short-haired cat was presented to her veterinarian with a mass on the hind paw. Histopathologic examination of a tissue biopsy revealed nodular pyogranulomatous panniculitis with intralesional pigmented fungal hyphae. A dematiaceous fungal isolate was isolated with a micromorphological phenotype consistent with the anamorphic genus Exophiala: budding cells, torulose mycelium and annellidic conidiogenesis from simple conidiophores consisting of terminal and lateral cells that tapered to a short beak at the apex. Sequence homology of the internal transcribed spacer region of the rDNA gene confirmed the identification of the isolate as Exophiala attenuata. Reported here is the first confirmed case of feline phaeohyphomycosis caused by E. attenuata in North America. Similar to historical cases of feline phaeohyphomycosis caused by Exophiala spp., there was no history or postmortem evidence to suggest the patient was in an immunocompromised state (e.g., suffering from FeLV or FIV). Although aggressive surgical excision of local lesions is recommended prior to drug treatment when dealing with subcutaneous phaeohyphomycosis, surgery followed by itraconazole treatment did not resolve the E. attenuata infection in this cat.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Overy DP,Martin C,Muckle A,Lund L,Wood J,Hanna P

doi

10.1007/s11046-015-9909-y

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

281-7

issue

3-4

eissn

0301-486X

issn

1573-0832

journal_volume

180

pub_type

杂志文章
  • Superficial mycoses observed at the Department of Dermatology of the University of Pavia. A 13-year survey.

    abstract::Over a period of 13 years, 4,100 specimens were cultured for fungi. Pityriasis versicolor (Malassezia furfur) was demonstrated in 17.6%, dermatophytosis in 34.6% and candidiasis in 10.8%. The most frequently isolated strains were M. canis (31.5%), T. rubrum (26.3%), E. floccosum (19.7%), T. mentagrophytes (19.3%) for ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00443824

    authors: Di Silverio A,Mosca M,Gatti M,Brandozzi G

    更新日期:1989-01-01 00:00:00

  • Fate of aflatoxin B-1 in fermented dairy products.

    abstract::Polyacrylamide gel electropheresis and thin layer chromatography (TLC) were applied to detect the fate of aflatoxin B-1 in milk fermented with an active culture of Streptococcus lactis (ATCC-11454). TLC analysis revealed the formation of two fluorescent metabolites (B2a and R0) in fermented milk. Electropheretic analy...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00439291

    authors: Megalla SE,Mohran MA

    更新日期:1984-10-30 00:00:00

  • Broth microdilution and time-kill testing of Caspofungin, voriconazole, amphotericin B and their combinations against clinical isolates of Candida krusei.

    abstract::Treatment of invasive Candida krusei infections can be difficult due to its intrinsic fluconazole resistance and its reduced susceptibility to amphotericin B and flucytosine. Caspofungin (CAS) acts on a different cellular target, and its combination with voriconazole (VOR) or amphotericin B (AmB) appears promising. We...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-011-9459-x

    authors: Oz Y,Dag I,Kiraz N

    更新日期:2012-01-01 00:00:00

  • Effects of penitrem A on rat's performances in passive avoidance and Morris water maze tests.

    abstract::Intraperitoneal administration of the mycotoxin penitrem A 30 min before a training session in passive avoidance task, impaired performance of rats subjected to a test-session 24 h after. This effect was not antagonised by pretraining administration of physostigmine or bicuculline. Administration of penitrem A 20 min ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1006853600205

    authors: Deschaux O,Bizot JC

    更新日期:1997-01-01 00:00:00

  • Natural occurrence of fumonisins and their correlation to Fusarium contamination in commercial corn hybrids growth in Argentina.

    abstract::Fifty commercial corn hybrids with different endosperm characteristics, vegetative cycle length and cross class grown in the same geographical area (Cordoba Province, Argentina) were analysed for fumonisin accumulation. All hybrids analysed showed fumonisin B(1) and B(2) contamination ranging from 185 to 27,050 ng/g f...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00436572

    authors: Ramirez ML,Pascale M,Chulze S,Reynoso MM,March G,Visconti A

    更新日期:1996-07-01 00:00:00

  • Granulomatous invasive aspergillosis of paranasal sinuses masquerading as actinomycosis and review of published literature.

    abstract::Cutaneous aspergillosis is a common systemic mycosis affecting immunosuppressed patients. Here, we describe a novel morphological type of cutaneous aspergillosis in a young immunocompetent woman who presented with a chronic history of multiple nodules and discharging sinuses over left side of the face, mimicking cervi...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/s11046-014-9732-x

    authors: Vinay K,Khullar G,Yadav S,Kanwar AJ,Saikia UN,Shivaprakash MR,Chakrabarti A,Dogra S

    更新日期:2014-04-01 00:00:00

  • Development of amphotericin B liposomes bearing antibody specific to Candida albicans.

    abstract::Liposomes expressing external antibody specific for Candida albicans and encapsulating amphotericin B were developed and characterized in this study. Antibody was first modified by the covalent attachment of palmitic acid residues. Liposomes were produced by reverse-phase evaporation and modified antibody was incorpor...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00455667

    authors: Hospenthal DR,Rogers AL,Mills GL

    更新日期:1988-01-01 00:00:00

  • Susceptibility and features of the ultrastructure of Prototheca zopfii following exposure to copper sulphate, silver nitrate and chlorexidine.

    abstract::One of the most important forms of the occurrence of protothecosis is bovine mastitis. Studies on the "in vivo" and "in vitro" susceptibility to antimicrobials have shown that the microorganism is resistant to most of them. Looking for alternative treatments this study aimed to study the susceptibility to copper sulph...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1021313118632

    authors: Melville PA,Benites NR,Sinhorini IL,Costa EO

    更新日期:2002-01-01 00:00:00

  • Cytologic findings in 43 cases of blastomycosis diagnosed ante-mortem in naturally-infected dogs.

    abstract::A retrospective study of the cytology of blastomycosis was undertaken. Sixty-one samples from 43 naturally infected dogs diagnosed ante-mortem by means of cytology were reviewed. Skin and lymph nodes rendered the highest number of positive samples with 17 out of 18 and 14 out of 17 respectively. Transtracheal washes c...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF01102884

    authors: Garma-Aviña A

    更新日期:1995-08-01 00:00:00

  • Entomophthora ferdinandii (Zygomycetes: Entomophthorales) causing natural infections of Musca domestica (Diptera: Muscidae) in Argentina.

    abstract::The identity and activity of an entomopathogenic fungus belonging to the Entomophthora muscae species complex and infecting Musca domestica in poultry houses from La Plata, Argentina, is reported. Entomophthora caused natural infections between September 2001 and September 2003. Primary conidia of this fungus were on ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-005-0248-2

    authors: Lastra CC,Siri A,García JJ,Eilenberg J,Humber RA

    更新日期:2006-04-01 00:00:00

  • Upper respiratory tract infection in mouse and rats.

    abstract::Spontaneous aspergilloma in the para-nasal cavities of 2 rats, and a chronic granuloma with grains, caused by Gram-positive cocci in the maxillary sinus of a mouse, are reported. ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00452893

    authors: Nyska A,Kuttin ES

    更新日期:1988-02-01 00:00:00

  • Decaying wood in tree trunk hollows as a natural substrate for Cryptococcus neoformans and other yeast-like fungi of clinical interest.

    abstract::The occurrence of Cryptococcus neoformans var. neoformans and other yeast-like fungi of clinical interest in decaying wood inside tree trunk hollows, bark and other plant materials is reported. The var. neoformans was isolated from 3 of 45 (6.6%) wood and one of 390 Eucalyptus bark samples. Two of the positive wood sa...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1010906220888

    authors: Randhawa HS,Mussa AY,Khan ZU

    更新日期:2001-01-01 00:00:00

  • Anti-Candida Activity of New Azole Derivatives Alone and in Combination with Fluconazole.

    abstract::The rate of Candida spp. infection is increasing, and resistance to azole antifungals is becoming increasingly common. Therefore, there is a need for discovery of new antifungal agents and for development of new modes of treatment using existing agents. In this in vitro study, the antifungal activity of two new imidaz...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-015-9899-9

    authors: Shi C,Liu C,Liu J,Wang Y,Li J,Xiang M

    更新日期:2015-10-01 00:00:00

  • Culture medium alkalinization by dermatophyes. (Influence of time and temperature of incubation).

    abstract::95 dermatophyte strains (12 of Trichophyton mentagrophytes, 12 of T. tonsurans, 11 of T. rubrum, 12 of T. megninii, 12 of T. violaceum, 2 of T. schoenleinii, 1 of T. soudanense, 12 of M. canis, 8 of Microsporum gypseum, 1 of M. ferrugineum and 12 of Epidermphoyton floccosum). 1 of Aspergillus niger, 1 of A. ochraceus,...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00467089

    authors: Paveia MH

    更新日期:1975-02-28 00:00:00

  • Clinical evolution of paracoccidioidomycosis in 38 children and teenagers.

    abstract::Paracoccidioidomycosis (PCM) in children is rare, and its clinical progression is not clearly understood. The admission and post-admission clinical records of 38 children and teenagers aged up to 14 were studied who had been under treatment for 24-30 months. It is a consecutive case series, 17 retrospective and 21 pro...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-005-3653-7

    authors: Nogueira MG,Andrade GM,Tonelli E

    更新日期:2006-02-01 00:00:00

  • Use of killer toxins for computer-aided differentiation of Candida albicans strains.

    abstract::Killer toxins were isolated from eight selected killer yeasts. Their activity on 100 Candida albicans isolates of human and animal origin was studied. A computer aided system for differentiating C. albicans strains was developed. By using this system, it was possible to differentiate 14 biotypes of C. albicans isolate...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00446297

    authors: Polonelli L,Castagnola M,Rossetti DV,Morace G

    更新日期:1985-09-01 00:00:00

  • Digestion of killed Paracoccidioides brasiliensis by neutrophils.

    abstract::We previously described an in vitro assay showing that neutrophils (PMNs) from patients with paracoccidioidomycosis (PARA) have a specific digestive deficiency against suspensions of live Paracoccidioides brasiliensis. We now report that this defect is equally detectable against autoclaved, but not Amphotericin B-kill...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00436927

    authors: Goihman-Yahr M,Rothenberg A,Bretaña A,Istúriz G,Rosquete R,Avila-Millán E,Viloria N,Saavedra de Borges N,Carrasquero M,Pérez de Fernández B

    更新日期:1989-04-01 00:00:00

  • Isolation of scopoletin from leaves of Hevea brasiliensis and the effect of scopoletin on pathogens of H. brasiliensis.

    abstract::Scopoletin (7-hydroxy-6-methoxy coumarin) which inhibited the conidial germination of Corynespora cassiicola was isolated from the uninfected mature leaves of Hevea brasiliensis. Scopoletin was not detected in uninfected immature rubber leaves. The immature leaves produced scopoletin after being infected with C. cassi...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1014910132595

    authors: Silva WP,Deraniyagala SA,Wijesundera RL,Karunanayake EH,Priyanka UM

    更新日期:2002-01-01 00:00:00

  • Trichophyton rubrum and Trichophyton interdigitale: genetic diversity among species and strains by random amplified polymorphic DNA method.

    abstract::Onychomycosis is a common condition that represents up to 50% of all nail problems and 30% of all cases of dermatophytoses. Trichophyton rubrum and Trichophyton interdigitale are the most common agents involved in this condition. In cases of recurrent post-treatment onychomycosis, strain fingerprinting could reveal wh...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-009-9261-1

    authors: Santos DA,Araújo RA,Hamdan JS,Cisalpino PS

    更新日期:2010-04-01 00:00:00

  • An overview of the immunopathology of human paracoccidioidomycosis.

    abstract::We review here the advances in the understanding of the immunopathology of human paracoccidioidomycosis (PCM). Its investigation must take in account the intriguing natural history of the mycosis and its agent, providing clues to the mechanisms that lead to development of disease (unbalanced host-parasite relationship...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/s11046-007-9065-0

    authors: Benard G

    更新日期:2008-04-01 00:00:00

  • Occurrence and population size of Malassezia spp. in the external ear canal of dogs and cats both healthy and with otitis.

    abstract::Malassezia yeasts are commensal organisms of human and animal skin that occasionally act as pathogens; lipid-dependent species are associated with human skin disorders. The aim of this work was to evaluate the occurrence, risk factors and population size of different species of Malassezia in the external ear canal of ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-005-0151-x

    authors: Cafarchia C,Gallo S,Capelli G,Otranto D

    更新日期:2005-09-01 00:00:00

  • Emergence of azole-resistant Candida albicans in small ruminants.

    abstract::Small ruminant production is a common agricultural activity worldwide. However, studies on the fungal microbiota of these animals are scarce. Therefore, this study aimed at isolating yeasts from goats and sheep and evaluating the antifungal susceptibility of the recovered Candida albicans. A total of 120 animals from ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-015-9888-z

    authors: Brilhante RS,Silva ST,Castelo-Branco DS,Teixeira CE,Borges LC,Bittencourt PV,de Oliveira JS,Monteiro AJ,Bandeira TJ,Cordeiro RA,Moreira JL,Sidrim JJ,Rocha MF

    更新日期:2015-10-01 00:00:00

  • Application of flow cytometry to differentiating Exophiala dermatitidis, E. moniliae and E. jeanselmei from each other.

    abstract::We applied a flow cytometry apparatus (FCM) to differentiating Exophiala dermatitidis, E. moniliae and E. jeanselmei from each other. The wavelength of the argon laser emitted from the FCM was 488 nm and the aperture of nozzle from which the stream of fluid containing single cells was blown out was 100 micron. By irra...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00441263

    authors: Taguchi H,Tanaka R,Nishimura K,Miyaji M

    更新日期:1988-08-01 00:00:00

  • In vivo interaction between alveolar macrophages and Cryptococcus neoformans.

    abstract::In vivo interactions of rabbit alveolar macrophages (AM) and Cryptococcus neoformans, a yeast pathogenic for humans, were studied. As a control, inert silica particles of a similar diameter (5-6 microns) were used. Of 16 rabbits, 6 were instilled intratracheally with fluorescein-labelled heat-killed C. neoformans, 6 w...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1006843202124

    authors: Nessa K,Gross NT,Jarstrand C,Johansson A,Camner P

    更新日期:1997-01-01 00:00:00

  • Fine structural studies of the Chrysosporium state of Renispora flavissima.

    abstract::Aspects of the fine structural characteristics of conidial and hyphal cells of the imperfect Chrysosporium state of the newly reported gymnoascaceous fungus, Renispora flavissima, are described and illustrated by electron micrographs of ultrathin sections. Preservation of the substructure of the thick-walled, smooth t...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00443903

    authors: Garrison RG,Mirikitani FK

    更新日期:1983-01-17 00:00:00

  • A natural focus of Histoplasma capsulatum var. duboisii is a bat cave.

    abstract::The natural reservoir of Histoplasma capsulatum var. duboisii, the etiological agent of histoplasmosis duboisii (African histoplasmosis) is not yet known. We report the isolation of H. capsulatum var. duboisii from soil admixed with bat guano and from the intestinal contents of a bat in a sandstone cave in a rural are...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF01102915

    authors: Gugnani HC,Muotoe-Okafor FA,Kaufman L,Dupont B

    更新日期:1994-09-01 00:00:00

  • Mycoflora and mycotoxins of Brazilian cashew kernels.

    abstract::Kernel samples of common and dwarf Brazilian cashew nuts were highly contaminated with field and storage fungi in comparison to healthy ones. In general, dwarf cashews were more contaminated than common. A total of 37 fungal species were identified. Aspergillus niger was the dominant species with more colonies being i...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1007081319685

    authors: Freire FC,Kozakiewicz Z,Paterson RR

    更新日期:1999-01-01 00:00:00

  • Effect of medicating ingredients and other additives on microflora present on swine and chicken feeds from a Manitoba mill.

    abstract::The occurrence of microfloral components on medicated and non-medicated swine and chicken feed pellets and crumbles, produced in a Manitoba feed mill between June 1991 and October 1992, was determined. Addition of medicates to feeds generally decreased bacterial incidence and increased that of Eurotium spp. fungi. The...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00436571

    authors: Mills JT,White ND,Woods SM

    更新日期:1996-01-01 00:00:00

  • Immunodiffusion test for diagnosing human pythiosis.

    abstract::An immunodiffusion test was developed for diagnosing subcutaneous and systemic pythiosis in humans. When culture filtrate antigen (CFA) from P. insidiosum was reacted against patient and rabbit antisera, 1-5 precipitin bands occurred both in patient and rabbit antisera, and a line of identity also occurred between pat...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00437089

    authors: Imwidthaya P,Srimuang S

    更新日期:1989-05-01 00:00:00

  • Identification of Pythium carolinianum causing 'root rot' of cotton in Egypt and its possible biological control by Pseudomonas fluorescens.

    abstract::A severe root rot disease of cotton caused by Pythium carolinianum was diagnosed in a cotton field in Beni-Musa village, 20 km southwest of El-Minia city, Egypt, during the summer of 1996. This was the first reported isolation of this fungus in Egypt. In the light of the importance of the cotton industry in Egypt, res...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/A:1006906212689

    authors: Abdelzaher HM,Elnaghy MA

    更新日期:1998-01-01 00:00:00