A radiographic, histological, and histometric study of endodontic materials.

Abstract:

:Silicone tubes filled with CRCS, a calcium hydroxide-based cement, were implanted at two different localizations in the right tibias of white male Wistar rats. A similar number of solid silicone rods were implanted in the left tibias of the same animals and were used as inert controls. Fifteen days after implantation the bone tissue reactions to these materials were evaluated by means of radiographic, histological, and histometric methods. The radiographic and histometric analysis of the tissues around the deep end of the implants showed that the amount of reactional bone formation in contact with CRCS was significantly lower than that observed in contact with the controls (p less than 0.01). Also, the cell counts obtained from the tissues in contact with CRCS were significantly less than those obtained from the controls (p less than 0.01). This methodology appears to be a refined procedure for analyzing the possible toxic effects of endodontic materials in bone tissues. However, we feel that more extensive experiments will be necessary before predicting the long-term results which could be obtained from this experimental model.

journal_name

J Endod

journal_title

Journal of endodontics

authors

Guglielmotti MB,Zmener O,Cabrini RL

doi

10.1016/S0099-2399(89)80090-1

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

1-5

issue

1

eissn

0099-2399

issn

1878-3554

pii

S0099-2399(89)80090-1

journal_volume

15

pub_type

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