Abstract：
:The administration of boldenone and androstadienedione to cattle is forbidden in the European Union, while prednisolone is permitted for therapeutic purposes. They are pseudoendogenous substances (endogenously produced under certain circumstances). The commonly used matrices in control analyses are urine or liver. With the aim of improving the residue controls, we previously validated a method for steroid analysis in bile. We now compare urine (a 'classic' matrix) to bile, both collected at the slaughterhouse, to understand whether the detection of steroids in the latter is easier. With the aim of having clearer results, we tested the presence of the synthetic corticosteroid dexamethasone. The results show that bile does not substantially improve the detection of boldenone, or its conjugates, prednisolone and prednisone. Dexamethasone, instead, was found in 10 out of 53 bovine bile samples, but only in one urine sample from the same animals. Bile could constitute a novel matrix for the analysis of residues in food-producing animals, and possibly not only of synthetic corticosteroids.
journal_name
Food Chemjournal_title
Food chemistryauthors
Chiesa L,Nobile M,Panseri S,Vigo D,Pavlovic R,Arioli Fdoi
10.1016/j.foodchem.2015.04.131subject
Has Abstractpub_date
2015-12-01 00:00:00pages
473-80eissn
0308-8146issn
1873-7072pii
S0308-8146(15)00688-3journal_volume
188pub_type
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