Abstract:
:Partial acid cleavage, comparative HPLC tryptic peptide mapping and amino acid sequencing of the C1 and C2 proteins of HeLa heterogeneous nuclear ribonucleoprotein (hnRNP) particles demonstrate that proteins C1 and C2 differ in primary structure by the presence of a 13 amino acid insert sequence in C2. This C2 insert sequence occurs after either glycine 106 or serine 107 in C1. The additional 13 amino acids that are present in C2 account for the observed molecular weight difference between the C1 and C2 hnRNP proteins on SDS polyacrylamide gel electrophoresis. Because C1 and C2 appear identical except for the 13 residue insert and because the 3' and 5' untranslated regions of the corresponding mRNAs also appear to be the same (Swanson et al., Mol. Cell. Biol. 7: 1731-1739), it is possible that both polypeptides are produced from a single transcription unit through an alternative splicing mechanism.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Merrill BM,Barnett SF,LeStourgeon WM,Williams KRdoi
10.1093/nar/17.21.8441subject
Has Abstractpub_date
1989-11-11 00:00:00pages
8441-9issue
21eissn
0305-1048issn
1362-4962journal_volume
17pub_type
杂志文章abstract::Bacteriophage T4 Dda helicase has recently been shown to be active as a monomer for unwinding of short duplex oligonucleotides and for displacing streptavidin from 3'-biotinylated oligonucleotides. However, its activity for streptavidin displacement and DNA unwinding has been shown to increase as the number of Dda mol...
journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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doi:10.1093/nar/22.20.4057
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
pub_type: 杂志文章
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journal_title:Nucleic acids research
pub_type: 杂志文章
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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更新日期:1988-11-11 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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journal_title:Nucleic acids research
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更新日期:2012-02-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2003-06-15 00:00:00
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doi:10.1093/nar/gkm1116
更新日期:2008-03-01 00:00:00
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journal_title:Nucleic acids research
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doi:10.1093/nar/26.13.3279
更新日期:1998-07-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2015-04-30 00:00:00
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journal_title:Nucleic acids research
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更新日期:1993-03-25 00:00:00
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更新日期:2008-03-01 00:00:00
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更新日期:1997-03-15 00:00:00
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更新日期:2012-07-01 00:00:00
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journal_title:Nucleic acids research
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更新日期:2001-05-15 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:1989-06-12 00:00:00
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journal_title:Nucleic acids research
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更新日期:2006-01-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/21.20.4726
更新日期:1993-10-11 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2001-08-01 00:00:00