Intradermal vaccination using the novel microneedle device MicronJet600: Past, present, and future.

abstract：:WHO defines adolescence age between 10 to 19 years. In India, there are 243 million adolescents which constitute 21 per cent of the total population. The global burden of disease in adolescents (2011) reports that the total number of disability adjusted life years (DALYs) worldwide among adolescents were 230 million w...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P,Chawla S

更新日期：2015-01-01 00:00:00

abstract：:Adjuvants produce complex, but often subtle, effects on vaccine-induced immune responses that, nonetheless, play a critical role in vaccine efficacy. In-depth profiling of vaccine-induced cytokine, cellular, and antibody responses ("immunoprofiling") combined with machine-learning holds the promise of identifying adju...

journal_title：Human vaccines & immunotherapeutics

authors： Chaudhury S,Duncan EH,Atre T,Dutta S,Spring MD,Leitner WW,Bergmann-Leitner ES

更新日期：2020-01-01 00:00:00

abstract：:A cohort of 81 HIV-infected participants received seasonal trivalent inactivated influenza vaccine (TIV) and their humoral responses were monitored using hemagglutination inhibition (HAI) assay and enzyme-linked immunosorbent assay (ELISA). Three weeks after the vaccination, the percentage of the cohort that had an HA...

journal_title：Human vaccines & immunotherapeutics

authors： Lau YF,Tang LH,Chien Lye D,Ooi EE,Leo YS

更新日期：2017-03-04 00:00:00

abstract：:Previously, we have shown that DNA prime-protein boost is effective in eliciting neutralizing antibodies (NAb) against randomly selected HIV-1 isolates. Given the genetic diversity of HIV-1 viruses and the unique predominant subtypes in different geographic regions, it is critical to test the DNA prime-protein boost a...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang M,Zhang L,Zhang C,Hong K,Shao Y,Huang Z,Wang S,Lu S

更新日期：2012-11-01 00:00:00

abstract：:Combined therapy using chemotherapeutic drugs and immunotherapeutics offers some promise for treating patients with cancer. In this study, we evaluated whether cisplatin delivered by intratumoral (IT)-electroporation (EP) might enhance antitumor activity against established B16 melanoma and whether further addition of...

journal_title：Human vaccines & immunotherapeutics

authors： Kim H,Sin JI

更新日期：2012-11-01 00:00:00

abstract：:Compared with the general population, patients with cancer in general are more susceptible to vaccine-preventable infections, either by an increased risk due to the malignancy itself or immunosuppressive treatment. The goal of immunizations in these patients is therefore to provide protection against these infections,...

journal_title：Human vaccines & immunotherapeutics

authors： Ariza-Heredia EJ,Chemaly RF

更新日期：2015-01-01 00:00:00

abstract：:MENK, a penta-peptide is considered as being involved in the regulatory feedback loop between the immune and neuroendocrine systems, with marked modulation of various functions of human immune cells. The aim of the present work was to investigate change of lymphocyte subpopulations in peripheral blood of 50 cancer pat...

journal_title：Human vaccines & immunotherapeutics

authors： Wang Q,Gao X,Yuan Z,Wang Z,Meng Y,Cao Y,Plotnikoff NP,Griffin N,Shan F

更新日期：2014-01-01 00:00:00

abstract：:Human enterovirus 71 (EV71) has been associated with outbreaks of hand-foot-and-mouth disease (HFMD) in China. Susceptibility to EV71 is associated with age, but few studies have been accomplished to measure such a relationship. A better understanding of the connection between susceptibility and age is necessary to de...

journal_title：Human vaccines & immunotherapeutics

authors： Tu X,Wang Y,Zhu F,Chen F

更新日期：2015-01-01 00:00:00

abstract：:Hepatitis A virus (HAV) is considered one of the most important vaccine-preventable diseases in travelers. HAV spreads from person to person via the fecal-oral route and gives rise to an estimated 1.4 million cases worldwide each year. In developing countries with poor sanitary conditions people tend to be infected du...

journal_title：Human vaccines & immunotherapeutics

authors： Aasheim ET,Seymour M,Balogun K,Ngui SL,Williams CJ,Shankar AG

更新日期：2013-11-01 00:00:00

abstract：:In Japan, government support for human papillomavirus (HPV) vaccination began in November 2010. However, the mass media repeatedly reported on severe adverse events. The Japanese Ministry of Health, Labor and Welfare suspended proactive recommendations for HPV vaccines in June 2013. Japan's HPV vaccination rate droppe...

journal_title：Human vaccines & immunotherapeutics

authors： Tozawa-Ono A,Kamada M,Teramoto K,Hareyama H,Kodama S,Kasai T,Iwanari O,Koizumi T,Ozawa N,Suzuki M,Kinoshita K

更新日期：2020-10-29 00:00:00

abstract：UNLABELLED:NmenB vaccine (4CMenB) is now available, but studies on the cost-effectiveness of vaccine introduction in a country outbreak situation are lacking. The aim of this study was to evaluate the cost-effectiveness of 4CMenB in the context of a hypothetical epidemic outbreak in Chile. We analyzed the direct and in...

journal_title：Human vaccines & immunotherapeutics

authors： Izquierdo G,Torres JP,Santolaya ME,Valenzuela MT,Vega J,Chomali M

更新日期：2015-01-01 00:00:00

abstract：:Introduction: The aim of this study was to determine the knowledge, attitudes, and practices of family physicians and pediatricians in regard to adolescent immunization.Methods: The study was conducted from March to May 2017. A total of 665 physicians participated. Participants were asked 31 questions about their pers...

journal_title：Human vaccines & immunotherapeutics

authors： Kara Elitok G,Bulbul L,Altuntas SB,Altuntas B,Günindi G,Haltaş M,Yuvarlan A,Toprak D,Bulbul A

更新日期：2020-05-03 00:00:00

abstract：:The immune system responds to tumor cells. The challenge has been how to effectively use these responses to treat or protect against cancer. Toward the goal of developing a cancer vaccine, we are pursuing methodologies for the discovery and testing of useful antigens. We present an array-based approach for discovering...

journal_title：Human vaccines & immunotherapeutics

authors： Whittemore K,Sykes K

更新日期：2013-10-01 00:00:00

abstract：:Influenza vaccination is the cornerstone of prophylaxis. The regulatory authorities currently annually license vaccines based on serum antibodies directed toward the major surface glycoprotein haemagglutinin (HA). The most commonly used serological test, the haemagglutination inhibition (HI) assay utilizes red blood c...

journal_title：Human vaccines & immunotherapeutics

authors： Cox RJ

更新日期：2013-02-01 00:00:00

abstract：:Group B streptococcus (GBS) is a leading bacterial cause of neonatal sepsis and meningitis in many countries as well as an important cause of disease in pregnant women. Currently, serotype-specific conjugate vaccines are being developed. We conducted an epidemiological analysis of health administrative data to estimat...

journal_title：Human vaccines & immunotherapeutics

authors： Hartley J,Li Y,Kunkel L,Crowcroft NS

更新日期：2019-01-01 00:00:00

abstract：:HIV vaccine strategies are expected to be a crucial component for controlling the HIV epidemic. Despite the large spectrum of potential candidate vaccines for both prophylactic and therapeutic use, the overall development process of an efficacious HIV vaccine strategy is lengthy. The design of clinical trials and the ...

journal_title：Human vaccines & immunotherapeutics

authors： Richert L,Lhomme E,Fagard C,Lévy Y,Chêne G,Thiébaut R

更新日期：2015-01-01 00:00:00

abstract：:High-dose inactivated, influenza vaccine was licensed by the FDA in December 2009 for adults aged 65 y and older. The ACIP did not issue or state a preference for a specific vaccine in the elderly population. The extent of its on-label and off-label use is unknown. Using the MarketScan Commercial Claims and Encounters...

journal_title：Human vaccines & immunotherapeutics

authors： McGrath LJ,Brookhart MA

更新日期：2015-01-01 00:00:00

abstract：:Rotavirus (RV) and norovirus (NoV) are the 2 leading causes of acute viral gastroenteritis worldwide. We have developed a non-live NoV and RV vaccine candidate consisting of NoV virus-like particles (VLPs) and recombinant polymeric RV VP6 protein produced in baculovirus-insect cell expression system. Both components h...

journal_title：Human vaccines & immunotherapeutics

authors： Blazevic V,Malm M,Arinobu D,Lappalainen S,Vesikari T

更新日期：2016-03-03 00:00:00

abstract：:Objective: To evaluate the efficacy of an intervention utilizing patient navigators (PNs) to 1) educate families on human papillomavirus (HPV) vaccination in a clinic setting and 2) provide personalized reminders for follow-up. Method: Families with 9-17 year-old children who had no record of completing the HPV vaccin...

journal_title：Human vaccines & immunotherapeutics

authors： Berenson AB,Rupp R,Dinehart EE,Cofie LE,Kuo YF,Hirth JM

更新日期：2019-01-01 00:00:00

abstract：:Salmonella enterica serovars Typhi and Paratyphi A and B and certain non-typhoidal Salmonella enterica (NTS) serovars are important causes of invasive Salmonella disease worldwide. NTS serovars Typhimurium and Enteritidis typically cause gastroenteritis in healthy children and adults in industrialized countries but in...

journal_title：Human vaccines & immunotherapeutics

authors： Simon R,Levine MM

更新日期：2012-04-01 00:00:00

abstract：:Rubella is a contagious viral disease, which mainly affects the fetus, if the mother is infected in the 1st trimester of her pregnancy. All adolescent girls (aged 11 to 19 y) and women of childbearing age are at risk of developing rubella. This disease is mild and self-limiting, and incubation period is 2-3 weeks. Hum...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P,Chawla S

更新日期：2012-06-01 00:00:00

abstract：:The 2014-2016 Ebola virus outbreak in West Africa led to advances in the development of vaccines against Ebola. This study examined factors associated with willingness to pay for an Ebola vaccine among a U.S. national sample during the recent Ebola outbreak. From April 30-May 8, 2015, a national survey was conducted u...

journal_title：Human vaccines & immunotherapeutics

authors： Painter JE,von Fricken ME,Viana de O Mesquita S,DiClemente RJ

更新日期：2018-07-03 00:00:00

abstract：:Despite strong national recommendations to vaccinate adolescents against the human papillomavirus (HPV), only 14% of teenage girls completed all 3 doses in 2010. Parental hesitancy may be one of the strongest reasons behind this low uptake rate. This review investigates sources of parental hesitancy including parental...

journal_title：Human vaccines & immunotherapeutics

authors： Patel PR,Berenson AB

更新日期：2013-12-01 00:00:00

abstract：:Varicella is a potentially serious infectious disease caused by Varicella-Zoster Virus (VZV). In Italy childhood varicella vaccine have gradually introduced into national immunization program since 2003 and from 2017 a two-doses schedule has been stated nationally for all newborns and has become compulsory for school ...

journal_title：Human vaccines & immunotherapeutics

authors： Balbi O,Baldi S,Rizza S,Pietroiusti A,Perrone S,Coppeta L

更新日期：2020-07-09 00:00:00

abstract：:Introduction: International tourism has grown tremendously in the past 2-3 decades in India resulting in exposure of travelers to varied spectrum of diseases prevalent in different parts of the world. Immunization plays a prominent role in protection of the exposed individuals. The objective of the present study was t...

journal_title：Human vaccines & immunotherapeutics

authors： Bhatia V,Palepu S,Parida SP,Singh AK,Sahoo SS

更新日期：2020-09-01 00:00:00

abstract：:In Chronic Myeloid Leukemia (CML), standard treatment consists of modern tyrosine-kinase inhibitors (TKI). Nevertheless, there is evidence that immune responses against leukemia-associated antigens (LAA) may play an important role in disease control. Dendritic cell (DC)- based immunotherapy is able to induce T cell re...

journal_title：Human vaccines & immunotherapeutics

authors： Flörcken A,Kopp J,Kölsch U,Meisel C,Dörken B,Pezzutto A,Westermann J

更新日期：2016-05-03 00:00:00

abstract：OBJECTIVES:Periodical assessments of population susceptibility to polioviruses (PV) is essential for evaluating population protection and planning appropriate vaccination strategies. The aim of the current work was to assess serological protective titers against all three polioviruses in the general population of Flore...

journal_title：Human vaccines & immunotherapeutics

authors： Giammanco GM,Bechini A,Urone N,Bonura F,Li Muli S,De Grazia S,Bellini I,Tiscione E,Boccalini S,Nastasi A

更新日期：2018-01-01 00:00:00

abstract：:We conducted a multicentre test negative case control study to estimate the 2013-14 influenza vaccine effectiveness (IVE) against hospitalised laboratory confirmed influenza in 12 hospitals in France, Italy and Spain. We included all ≥18 years hospitalised patients targeted by local influenza vaccination campaign repo...

journal_title：Human vaccines & immunotherapeutics

authors： Rondy M,Castilla J,Launay O,Costanzo S,Ezpeleta C,Galtier F,de Gaetano Donati K,Moren A

更新日期：2016-05-03 00:00:00

abstract：:One of the major obstacles to achieving complete eradication of tumors, even in the presence of circulating tumor-specific immunity, is the tumor-induced immunosuppressive environment, which includes myeloid-derived suppressor cells and regulatory T cells. Attenuated microorganisms have emerged as candidates for a nov...

journal_title：Human vaccines & immunotherapeutics

authors： Chang SY,Kim YJ,Ko HJ

更新日期：2013-08-01 00:00:00

abstract：:Group A rotavirus (RV-A) genotypes isolated in Malaysia was studied to estimate the effectiveness of a universal RV-A vaccination in Malaysia. A simple mathematical model was used, with input from a two-year, two-center, prospective study on hospitalization of RV-A gastroenteritis (RVGE) in young children, published d...

journal_title：Human vaccines & immunotherapeutics

authors： Lee WS,Lim BT,Chai PF,Kirkwood CD,Lee JK

更新日期：2012-10-01 00:00:00