Rotavirus capsid VP6 protein acts as an adjuvant in vivo for norovirus virus-like particles in a combination vaccine.

abstract：:Meningococcal serogroup B (MenB) is the predominant cause of invasive meningococcal disease in the United States, with older adolescents and young adults attending college at increased risk. Notably, MenB caused all meningococcal disease outbreaks at US colleges between 2011 and 2018. MenB disease is vaccine-preventab...

journal_title：Human vaccines & immunotherapeutics

authors： McDaniel A,Dempsey A,Srivastava A

更新日期：2019-01-01 00:00:00

abstract：:The introduction of human papillomavirus (HPV) vaccination in China aims to prevent HPV infection in all women. The issues that China might face include high cost of vaccines made in other countries, shortage in HPV vaccine supply, negative events attributed to vaccination (whether justified or not) that jeopardizes t...

journal_title：Human vaccines & immunotherapeutics

authors： Wong LP,Han L,Li H,Zhao J,Zhao Q,Zimet GD

更新日期：2019-01-01 00:00:00

abstract：:Polymeric carriers in the form of cellulose acetate phthalate (CAP) and alginate (ALG) microspheres were used for encapsulation of plasmid DNA for oral mucosal immunization. Access into the intestinal mucosa by pVAX1 eukaryotic expression plasmid vectors carrying gene-coding sequences, either for the cholera enterotox...

journal_title：Human vaccines & immunotherapeutics

authors： Rosli R,Nograles N,Hanafi A,Nor Shamsudin M,Abdullah S

更新日期：2013-10-01 00:00:00

abstract：:Aim: This research investigated the therapeutic effect of an allogeneic mouse brain microvascular endothelial cell vaccine on lung cancer and further elucidated its potential anti-angiogenic mechanism. Materials & methods: The immune effect of the allogeneic bEnd.3 vaccine and DC vaccine loaded with bEnd.3 antigen on ...

journal_title：Human vaccines & immunotherapeutics

authors： Zhao J,Zhang X,Du Y,Zhou L,Dong Z,Zhao J,Lu J

更新日期：2020-05-27 00:00:00

abstract：:Influenza vaccination aims at reducing the incidence of serious disease, complications and death among those with the most risk of severe influenza disease. Influenza vaccine effectiveness (VE) through sentinel surveillance data from the PIDIRAC program (Daily Acute Respiratory Infection Surveillance of Catalonia) dur...

journal_title：Human vaccines & immunotherapeutics

authors： Torner N,Martínez A,Basile L,Marcos MA,Antón A,Mar Mosquera M,Isanta R,Cabezas C,Jané M,Domínguez A,Program Of Catalonia TP

更新日期：2015-01-01 00:00:00

abstract：:Individuals infected with human immunodeficiency virus (HIV) have excess risk of developing human papillomavirus (HPV)-related disease. A substantial fraction of HPV-associated cancers is caused by HPV serotypes not included in the currently available vaccines. Among healthy women, both Cervarix(®) (HPV-16/18, GlaxoSm...

journal_title：Human vaccines & immunotherapeutics

authors： Toft L,Tolstrup M,Müller M,Sehr P,Bonde J,Storgaard M,Østergaard L,Søgaard OS

更新日期：2014-01-01 00:00:00

abstract：:Compared with the general population, patients with cancer in general are more susceptible to vaccine-preventable infections, either by an increased risk due to the malignancy itself or immunosuppressive treatment. The goal of immunizations in these patients is therefore to provide protection against these infections,...

journal_title：Human vaccines & immunotherapeutics

authors： Ariza-Heredia EJ,Chemaly RF

更新日期：2015-01-01 00:00:00

abstract：:Despite strong national recommendations to vaccinate adolescents against the human papillomavirus (HPV), only 14% of teenage girls completed all 3 doses in 2010. Parental hesitancy may be one of the strongest reasons behind this low uptake rate. This review investigates sources of parental hesitancy including parental...

journal_title：Human vaccines & immunotherapeutics

authors： Patel PR,Berenson AB

更新日期：2013-12-01 00:00:00

abstract：:A novel coronavirus (2019-nCov) emerged in China, at the end of December 2019 which posed an International Public Health Emergency, and later declared as a global pandemic by the World Health Organization (WHO). The International Committee on Taxonomy of Viruses (ICTV) named it SARS-CoV-2 (Severe Acute Respiratory Syn...

journal_title：Human vaccines & immunotherapeutics

authors： Siddique R,Bai Q,Shereen MA,Nabi G,Han G,Rashid F,Ahmed S,Benzhanova A,Xue M,Khan S

更新日期：2020-10-16 00:00:00

abstract：:One of the major obstacles to achieving complete eradication of tumors, even in the presence of circulating tumor-specific immunity, is the tumor-induced immunosuppressive environment, which includes myeloid-derived suppressor cells and regulatory T cells. Attenuated microorganisms have emerged as candidates for a nov...

journal_title：Human vaccines & immunotherapeutics

authors： Chang SY,Kim YJ,Ko HJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Over the past decade, there have been resurgences and large-scale outbreaks of mumps worldwide. Little evidence is available on the relationship between meteorological factors and the incidence of mumps. We aimed to explore the effects of meteorological factors on mumps incidence. METHODS:A Poisson regressi...

journal_title：Human vaccines & immunotherapeutics

authors： Yang Q,Yang Z,Ding H,Zhang X,Dong Z,Hu W,Liu X,Wang M,Hu G,Fu C

更新日期：2014-01-01 00:00:00

abstract：:A 9-valent HPV (9vHPV) vaccine has been developed to protect against HPV type 6/11/16/18/31/33/45/52/58-related infection and disease. Previous safety analyses from 7 clinical trials conducted in 9vHPV vaccine recipients 9-26 years of age, including comparisons of 9vHPV and quadrivalent HPV (qHPV) vaccines in girls an...

journal_title：Human vaccines & immunotherapeutics

authors： Moreira ED,Giuliano AR,de Hoon J,Iversen OE,Joura EA,Restrepo J,Van Damme P,Vandermeulen C,Ellison MC,Krick A,Shields C,Heiles B,Luxembourg A

更新日期：2018-02-01 00:00:00

abstract：:Dynamically changing social situation associated with migrations, increasing freedom rights, popularity of anti-vaccine movements and the resulting from that decrease in herd immunity, forces the medical society and the governments of various countries to reflect on the attitude toward vaccinations. Issues of freedoms...

journal_title：Human vaccines & immunotherapeutics

authors： Patryn RK,Zagaja A

更新日期：2016-08-02 00:00:00

abstract：:There is currently a lack of sufficient data on human papillomavirus (HPV)-attributable cervical carcinoma in China. Accordingly, we aimed to determine the prevalence and genotype distribution of HPV among women with cervical lesions in Shenzhen, in order to evaluate the potential benefit of HPV vaccination programs a...

journal_title：Human vaccines & immunotherapeutics

authors： Mai Q,Yang X,Cheng H,Wu G,Wu Z

更新日期：2020-09-22 00:00:00

abstract：:Different strategies have been proposed for the development of protein subunit vaccine candidates for tuberculosis (TB), which shows better safety than other types of candidates and the currently used Bacillus Calmette-Guérin (BCG) vaccine. In order to develop more effective protein subunits depending on the mechanism...

journal_title：Human vaccines & immunotherapeutics

authors： Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X

更新日期：2015-01-01 00:00:00

abstract：:We aimed to determine the efficacy of the 10-valent pneumococcal-Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in children aged 18-months to <18-years with recurrent protracted bacterial bronchitis (rPBB), chronic suppurative lung disease (CSLD) or bronchiectasis. In a multi-centre, double-blind randomi...

journal_title：Human vaccines & immunotherapeutics

authors： O'Grady KF,Chang AB,Cripps A,Mulholland EK,Smith-Vaughan H,Wood N,Danchin M,Thornton R,Wilson A,Torzillo PJ,Morris PM,Richmond P,Rablin S,Arnold D,Connor A,Goyal V,Stoney T,Perrett K,Grimwood K

更新日期：2018-01-01 00:00:00

abstract：:The 4-component vaccine 4CMenB, developed against invasive disease caused by meningococcal serogroup B, is approved for use in infants in several countries worldwide. 4CMenB is mostly used as 3 + 1 schedule, except for the UK, where a 2 + 1 schedule is used, and where the vaccine showed an effectiveness of 82.9%. Here...

journal_title：Human vaccines & immunotherapeutics

authors： Biolchi A,Tomei S,Santini L,Welsch JA,Toneatto D,Gaitatzis N,Bai X,Borrow R,Giuliani MM,Mori E,Pizza M

更新日期：2019-01-01 00:00:00

abstract：:The study of influenza virus evolution in humans has revealed a significant role of glycosylation profile alterations in the viral glycoproteins - hemagglutinin (HA) and neuraminidase (NA), in the emergence of both seasonal and pandemic strains. Viral antigenic drift can modify the number and location of glycosylation...

journal_title：Human vaccines & immunotherapeutics

authors： Cruz E,Cain J,Crossett B,Kayser V

更新日期：2018-03-04 00:00:00

abstract：:Some health care providers have adopted the policy of refusing to accept into their practices families who refuse to vaccinate their children according to the standard vaccine schedule. While the frustration that drives these policies is understandable, the practice of refusing to see these families is misguided. Such...

journal_title：Human vaccines & immunotherapeutics

authors： Diekema DS

更新日期：2013-12-01 00:00:00

abstract：:Senate Bill 277 (SB277) eliminated nonmedical exemptions for school-entry vaccines in California, but the impact of parental vaccine knowledge, attitudes, and beliefs on vaccine decision-making has not been extensively examined within the post-SB277 context. This study generates preliminary understanding and discussio...

journal_title：Human vaccines & immunotherapeutics

authors： Holroyd TA,Howa AC,Delamater PL,Klein NP,Buttenheim AM,Limaye RJ,Proveaux TM,Omer SB,Salmon DA

更新日期：2020-11-24 00:00:00

abstract：INTRODUCTION:Enterovirus A71(EV-A71)-associated hand, foot, and mouth disease (HFMD) has been reported worldwide, and poses a particularly heavy burden on patients, families, and society in China. Three Chinese companies have licensed inactivated EV-A71 vaccines, all of which have demonstrated good efficacy for prevent...

journal_title：Human vaccines & immunotherapeutics

authors： Wang X,An Z,Huo D,Jia L,Li J,Yang Y,Liang Z,Wang Q,Wang H

更新日期：2019-01-01 00:00:00

abstract：:Alzheimer disease is a devastating chronic disease without adequate therapy. More than 10 years ago, it was demonstrated in transgenic mouse models that vaccination may be a novel, disease-modifying therapy for Alzheimer. Subsequent clinical development has been a roller-coaster with some positive and many negative ne...

journal_title：Human vaccines & immunotherapeutics

authors： Fettelschoss A,Zabel F,Bachmann MF

更新日期：2014-01-01 00:00:00

abstract：:Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), is a major health problem particularly in developing countries. The available vaccines have certain limitations regarding their efficacy, and inability to induce an immune response especially in individuals under 2 years of age. Conjugate vaccines ...

journal_title：Human vaccines & immunotherapeutics

authors： Ali A,An SJ,Cui C,Haque A,Carbis R

更新日期：2012-02-01 00:00:00

abstract：:Rotavirus gastroenteritis accounts for an estimated 130,000 GP consultations and 13,000 hospitalisations for children under 5 y old each year in England and Wales. In July 2013, an oral live attenuated rotavirus vaccine (Rotarix®) was introduced into the UK infant immunisation program as a 2 dose schedule at 2 and 3 m...

journal_title：Human vaccines & immunotherapeutics

authors： Inns T,Trindall A,Dunling-Hall S,Shankar AG

更新日期：2016-04-02 00:00:00

abstract：OBJECTIVE:To study the awareness and acceptance of human papillomavirus (HPV) vaccination among sexually active men having sex with men (MSM) and men not having sex with men (MNSM) attending the largest sexual health clinic in Wuxi, China. METHODS:A questionnaire about participants' socio-demographic characteristics a...

journal_title：Human vaccines & immunotherapeutics

authors： Zou H,Meng X,Jia T,Zhu C,Chen X,Li X,Xu J,Ma W,Zhang X

更新日期：2016-06-02 00:00:00

abstract：:The 2014-2016 Ebola virus outbreak in West Africa led to advances in the development of vaccines against Ebola. This study examined factors associated with willingness to pay for an Ebola vaccine among a U.S. national sample during the recent Ebola outbreak. From April 30-May 8, 2015, a national survey was conducted u...

journal_title：Human vaccines & immunotherapeutics

authors： Painter JE,von Fricken ME,Viana de O Mesquita S,DiClemente RJ

更新日期：2018-07-03 00:00:00

abstract：:Ebola virus disease (EVD) has become a great threat to humans across the world in recent years. The 2014 Ebola epidemic in West Africa caused numerous deaths and attracted worldwide attentions. Since no specific drugs and treatments against EVD was available, vaccination was considered as the most promising and effect...

journal_title：Human vaccines & immunotherapeutics

authors： Wang Y,Li J,Hu Y,Liang Q,Wei M,Zhu F

更新日期：2017-01-02 00:00:00

abstract：:Within the past few years, several measles outbreaks have occurred in the southeast of Iran. To learn about the effectiveness of the immunization services for producing a serologic response against measles, this follow-up study was designed and implemented in the southeast of Iran. In Iran, all routine immunization se...

journal_title：Human vaccines & immunotherapeutics

authors： Zahraei SM,Izadi S,Mokhtari-Azad T

更新日期：2016-12-01 00:00:00

abstract：:Background: We performed a systematic review to evaluate factors affecting uptake of rotavirus vaccine amongst physicians, parents and health system. Methods: We identified 15 studies that met the inclusion criteria from 790 screened studies published between Jan 2005 to Jan 2016. Results: Perceived severity of rotavi...

journal_title：Human vaccines & immunotherapeutics

authors： Apte A,Roy S,Bavdekar A,Juvekar S,Hirve S

更新日期：2018-01-01 00:00:00

abstract：:In tick-borne encephalitis (TBE)-endemic regions, long-term vaccination programs are efficient in preventing the disease. A booster dose of a polygeline-free inactivated TBE vaccine (Encepur Adults, GSK), administered approximately 3 years post-primary vaccination according to 1 of 3 licensed vaccination schedules in ...

journal_title：Human vaccines & immunotherapeutics

authors： Costantini M,Callegaro A,Beran J,Berlaimont V,Galgani I

更新日期：2020-09-01 00:00:00