Abstract:
:Emotional and role functioning difficulties are associated with chronic alcohol use and liver disease. Little is known about prospective changes in psychological and psychosocial functioning following orthotopic liver transplantation (OLT) amongst patients with alcoholic liver disease (ALD). We aimed to assess the functioning of this patient group post liver transplantation. Comprehensive psychosocial assessment of depression (Beck Depression Inventory [BDI]), anxiety (State-Trait Anxiety Inventory-Form X [STAI]) and psychosocial adjustment (Psychosocial Adjustment to Illness Scale-Self-Report version [PAIS-SR]) was conducted with 42 ALD patients available for pre and post OLT testing. Dependence severity was assessed by the Brief Michigan Alcoholism Screening Test (bMAST). Significant reductions in average anxiety and depression symptoms were observed 12-months post-OLT. Significant improvements in psychosocial adjustment to illness were also reported. Patients with higher levels of alcohol dependence severity pre transplant assessment improved comparably to those with lower levels of dependence. In summary, the study found that OLT contributed to reducing overall levels of mood and anxiety symptoms in ALD patients, approximating general (non-clinical) population norms. Psychosocial adjustment also improved significantly post liver transplantation.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Pegum N,Connor JP,Young RM,Feeney GFdoi
10.1016/j.addbeh.2015.01.021subject
Has Abstractpub_date
2015-06-01 00:00:00pages
70-3eissn
0306-4603issn
1873-6327pii
S0306-4603(15)00022-2journal_volume
45pub_type
杂志文章abstract::Initial sensitivity to substances may affect patterns of future use and dependence. Because smoking and alcohol use are strongly linked, because animal studies indicate cross-sensitivity, and because genetic determinants of nicotine and alcohol dependence overlap, we studied the relationships between retrospectively r...
journal_title:Addictive behaviors
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journal_title:Addictive behaviors
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journal_title:Addictive behaviors
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journal_title:Addictive behaviors
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journal_title:Addictive behaviors
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journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
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journal_title:Addictive behaviors
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Addictive behaviors
pub_type: 杂志文章
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journal_title:Addictive behaviors
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journal_title:Addictive behaviors
pub_type: 杂志文章
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journal_title:Addictive behaviors
pub_type: 杂志文章
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journal_title:Addictive behaviors
pub_type: 杂志文章
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