Sarcopenia Defined by Combining Height- and Weight-Adjusted Skeletal Muscle Indices is Closely Associated With Poor Physical Performance.

Abstract:

OBJECTIVES:To compare muscle strength and physical performance among subjects with and without sarcopenia of different definitions. DESIGN:A population-based cross-sectional study. PARTICIPANTS:857 community residents aged 65 years or older. METHODS:Sarcopenia was defined according to the European Working Group of Sarcopenia in Older People consensus criteria. Dual-energy X-ray absorptiometry measured lean soft tissue mass. Sarcopenic participants with low height-adjusted or weight-adjusted skeletal muscle index (SMI) were classified as having h-sarcopenia or w-sarcopenia, respectively. Combined sarcopenia (c-sarcopenia) was defined as having either h- or w-sarcopenia. The participants underwent six physical performance tests: walking speed, timed up-and-go, six-minute walk, single-leg stance, timed chair stands, and flexibility test. The strength of five muscle groups was measured. RESULTS:Participants with h-sarcopenia had lower weight, body mass index (BMI), fat mass, and absolute muscle strength (p ≤ .001); those with w-sarcopenia had higher weight, BMI, fat mass (p < .001), and low relative muscle strength (p ≤ .003). Participants with c-sarcopenia had poorer performance in all physical performance tests, whereas h-sarcopenia and w-sarcopenia were associated with poor performance in four tests. CONCLUSION:Subjects with h- and w-sarcopenia differ significantly in terms of obesity indicators. Combining height- and weight-adjusted SMIs can be a feasible method to define sarcopenia.

journal_name

J Aging Phys Act

authors

Meng NH,Li CI,Liu CS,Lin WY,Lin CH,Chang CK,Li TC,Lin CC

doi

10.1123/japa.2014-0036

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

597-606

issue

4

eissn

1063-8652

issn

1543-267X

pii

2014-0036

journal_volume

23

pub_type

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