Sex-, age-, and height-specific reference curves for the 6-min walk test in healthy children and adolescents.


UNLABELLED:The 6-min walk test is a simple and accurate method to measure functional exercise capacity in children. We provide smooth reference curves for the modified 6-min walk test in 696 healthy children and adolescents aged 4-19 years, enabling calculation of sex-, age-, and height-specific Z-scores. CONCLUSION:These reference curves will allow more accurate grading of mobility and exercise capacity in sick or disabled children and monitoring the effects of intervention or treatment.


Eur J Pediatr


Saraff V,Schneider J,Colleselli V,Ruepp M,Rauchenzauner M,Neururer S,Geiger R,Högler W




Has Abstract


2015-06-01 00:00:00












  • A mobile Meckel!

    abstract::A technetium-99m pertechnetate Meckel scan is the standard diagnostic test to diagnose Meckel diverticulum. Although a negative scan does not exclude Meckel diverticulum, it should be kept in mind that the diagnosis can be missed on the basis of a single negative scan. Another important point is the typical position o...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: El-Matary W,Roseman D,Lees G,Maguire C

    更新日期:2009-12-01 00:00:00

  • Quality of life and behavioral functioning in Dutch pediatric patients with hereditary spherocytosis.

    abstract:UNLABELLED:The objective of this study was to evaluate health-related quality of life (HRQoL) and behavioral functioning in pediatric patients with hereditary spherocytosis (HS). A cross-sectional study was conducted in 132 Dutch children and adolescents with HS and aged 8-18 years of whom 48 underwent splenectomy prio...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Teunissen M,Hijmans CT,Cnossen MH,Bronner MB,Grootenhuis MA,Peters M

    更新日期:2014-09-01 00:00:00

  • Growth hormone treatment in a child with Williams-Beuren syndrome: a case report.

    abstract:UNLABELLED:Growth retardation is a consistent finding in Williams-Beuren syndrome. The cause of short stature in this syndrome is unknown. Endocrine studies have failed to reveal abnormalities in the growth hormone-insulin-like growth factor I axis. We report a boy with confirmed Williams-Beuren syndrome, who was found...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Kuijpers GM,De Vroede M,Knol HE,Jansen M

    更新日期:1999-06-01 00:00:00

  • Pharmacokinetics of piritramide in newborns, infants and young children in intensive care units.

    abstract::Piritramide is indicated for treatment of postoperative pain and analgosedation in the intensive care unit (ICU) setting. In an open prospective study the pharmacokinetics of piritramide were investigated in four groups: newborns (NB, age: 1-28 days) (n=8), infants 1 (IF1, age: 2-4 months) (n=7), infants 2 (IF2, age: ...

    journal_title:European journal of pediatrics

    pub_type: 临床试验,杂志文章


    authors: Müller C,Kremer W,Harlfinger S,Doroshyenko O,Jetter A,Hering F,Hünseler C,Roth B,Theisohn M

    更新日期:2006-04-01 00:00:00

  • Male pseudohermaphroditism due to 5 alpha-reductase deficiency in a Swedish family.

    abstract::Three sibs with an inherited form of male pseudohermaphroditism are described. They were all born with ambiguous external genitalia but no diagnosis of a possible enzyme defect was made during childhood. First seen at the ages of 16, 14 and 10 years respectively, they were investigated in order to establish the pathog...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Ivarsson SA,Nielsen MD,Lindberg T

    更新日期:1988-06-01 00:00:00

  • Prevalence of coeliac disease in diabetic children and adolescents. A multicentre study.

    abstract::Screening for coeliac disease (CD) with serum antigliadin antibodies (AGA) was performed in 1032 diabetic children and adolescents. In 8 children CD had been diagnosed before study entry. Of the remaining 1024 children, 33 had an elevated AGA titre in the first serum sample. On follow-up an elevated AGA titre was conf...

    journal_title:European journal of pediatrics

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Koletzko S,Bürgin-Wolff A,Koletzko B,Knapp M,Burger W,Grüneklee D,Herz G,Ruch W,Thon A,Wendel U

    更新日期:1988-11-01 00:00:00

  • Population pharmacokinetics of doxapram in low-birth-weight Japanese infants with apnea.

    abstract:UNLABELLED:This study aimed to determine the population pharmacokinetics of doxapram in low-birth-weight (LBW) infants. A total of 92 serum concentration measurements that were obtained from 34 Japanese neonates were analyzed using nonlinear mixed-effect modeling (NONMEM). Estimates generated by NONMEM indicated that c...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Ogawa Y,Irikura M,Kobaru Y,Tomiyasu M,Kochiyama Y,Uriu M,Ishitsuka Y,Kondo Y,Yukawa E,Kamada N,Ohno H,Yamazaki T,Irie T

    更新日期:2015-04-01 00:00:00

  • Successful resumption of trimethoprim-sulfamethoxazole after oral desensitisation in patients with chronic granulomatous disease.

    abstract::Two patients with chronic granulomatous disease who had previously been intolerant to trimethoprim-sulfamethoxazole because of various adverse reactions completed a desensitisation protocol with a favourable clinical outcome. ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Hasui M,Kotera F,Tsuji S,Yamamoto A,Taniuchi S,Fujikawa Y,Nakajima M,Yoshioka A,Kobayashi Y

    更新日期:2002-06-01 00:00:00

  • Intracranial bleeding during therapy with L-asparaginase in childhood acute lymphocytic leukemia.

    abstract::Two patients developed clinical features of intracranial bleeding--which were confirmed by computerized axial tomograms--during their induction therapy for acute lymphocytic leukemia. Coagulation studies showed clotting abnormalities including severe hypofibrinogenemia. These findings most probably were related to the...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Urban C,Sager WD

    更新日期:1981-11-01 00:00:00

  • Familial trisomy 9p and spinal muscular atrophy: clinical, cytogenetic and embryological findings.

    abstract::The pre- and postnatal clinical, cytogenetic and embryological findings in a family suffering from trisomy 9p and spinal muscular atrophy are presented. The clinical picture of the "trisomy 9p" -syndrome is delineated. Concurrence of autosomal aberration and spinal muscular atrophy, probably of the Werdnig-Hoffmann ty...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Tolksdorf M,Kunze J,Gross-Selbeck G,Sperling K,Wegner RD,Wieczorek V,Vogel M

    更新日期:1977-08-23 00:00:00

  • Echocardiographic assessment of hemodynamic changes in preterm neonates with shock: a prospective pragmatic cohort study.

    abstract::Shock is a state of circulatory dysfunction and its diagnosis is complex in neonates. Hemodynamic assessment using echocardiography has potential to guide better management regimes in neonates with shock. Objective of this study is to analyze changes in the echocardiographic parameters in preterm neonates with shock a...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Pawale D,Murki S,Kulkarni D,Vardhelli V,Sharma D,Oleti T,Kiran S,Bakhru S,Koneti NR

    更新日期:2020-12-01 00:00:00

  • Esophageal perforation in very low birth weight infants.

    abstract::We aimed to assess the prevalence and outcomes of esophageal perforation in very low birth weight infants. This retrospective cohort study utilized the US National Inpatient Sample dataset for the years 2000 to 2017. A total of 1,755,418 very low birth weight infants were included; of them, 861 (0.05%) were diagnosed ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Elgendy MM,Othman H,Aly H

    更新日期:2021-02-01 00:00:00

  • Infrared thermography: experience from a decade of pediatric imaging.

    abstract::The aim of this study was to evaluate the feasibility of clinical application of infrared thermography (IRT) in the pediatric population and to identify pathological states that can be diagnosed as well as followed up using this non-invasive technique. In real time computer-assisted IRT, 483 examinations were performe...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Saxena AK,Willital GH

    更新日期:2008-07-01 00:00:00

  • Association of increased numbers of peripheral blood double-negative T-lymphocytes with elevated serum IgG levels in severely handicapped children.

    abstract::CD3+4-8- double negative cells in peripheral blood lymphocytes were examined in 21 severely handicapped children divided into two groups according to serum IgG level. All children were bedridden and were taking multiple anticonvulsants and there were no apparent clinical differences between these two groups. Serum lev...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Kawano Y,Noma T,Yoshizawa I,Maruki K,Yata J

    更新日期:1994-12-01 00:00:00

  • Successful prenatal treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

    abstract::A mother carrying a fetus affected with 21-hydroxylase deficiency received prenatal treatment with dexamethasone (0.5 mg, tid, p.o.) started from the very beginning of the 8th week of gestation. Prenatal diagnosis had to rely on amniocentesis with karyotyping and steroid hormone determination, because HLA and DNA data...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Wudy SA,Homoki J,Teller WM

    更新日期:1994-08-01 00:00:00

  • Crohn disease with sclerosing cholangitis and liver cirrhosis in adolescence.

    abstract::A 17-year-old patient suffering from Crohn disease (CD) and liver cirrhosis is presented. At an advanced stage of the disease, he died of a concomitant urosepsis. Autopsy showed that the liver cirrhosis was caused by sclerosing cholangitis. This very rare complication of CD in adolescence is discussed. ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Ramelli GP,Tönz O,Zimmermann A,Lentze MJ

    更新日期:1991-06-01 00:00:00

  • Fear effects by the media.

    abstract:UNLABELLED:Both news media and entertainment fiction may lead to short-term and enduring fright reactions. Even TV programs, movies and news made for children may trigger fear. Preoperational children (3 to 7 years of age) are most afraid of fantasy characters, transformations and interpersonal violence. Operational ch...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Custers K,Van den Bulck J

    更新日期:2012-04-01 00:00:00

  • In vivo propionate oxidation as a prognostic indicator in disorders of propionate metabolism.

    abstract::Biochemical markers such as plasma and urinary metabolite concentrations and in vitro enzyme activity are of limited prognostic value in the most common disorders of propionate metabolism, methylmalonic acidaemia (MMA) and propionic acidaemia (PA). In vivo propionate oxidation was compared with conventional prognostic...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Thompson GN,Walter JH,Bresson JL,Bonnefont JP,Saudubray JM,Leonard JV,Halliday D

    更新日期:1990-03-01 00:00:00

  • Management of neurogenic bladder dysfunction secondary to myelomeningocele.

    abstract::We investigated 55 children, aged from 24 months to 14 years with neurogenic bladder dysfunction secondary to myelomeningocele, by serial urodynamic. They were serially evaluation over 2-5 years. Management consisted of drug therapy together with intermittent vesical catheterization in different combinations on the ba...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Castro-Gago M,Novo I,Cimadevila A,Peña J,Rodriguez-Núñez A,Marqués'-Queimadelos A

    更新日期:1990-11-01 00:00:00

  • Agranulocytosis following infectious mononucleosis.

    abstract::A girl developed acute agranulocytosis (45/mm3), 37 days after the onset of infectious mononucleosis. The bone marrow showed myeloid hyperplasia with maturation arrest and erythroid hypoplasia. A normal amount of colony forming units of granulocytes and macrophages (CFU-GM) colonies with a relative high number of clus...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Sumimoto S,Kasajima Y,Hamamoto T,Miyanomae T,Iwai Y,Mayumi M,Mikawa H

    更新日期:1990-07-01 00:00:00

  • Predictive factors for the effect of gonadotrophin releasing hormone analogue therapy on the height of girls with idiopathic central precocious puberty.

    abstract::The factors influencing the final height of central precocious puberty patients treated with gonadotrophin releasing hormone (GnRH) analogues remain a critical issue. This study compares the predicted final height before and after GnRH analogue therapy to identify predictive factors for final height. Fourteen girls wi...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Brauner R,Malandry F,Rappaport R

    更新日期:1992-10-01 00:00:00

  • Two-year outcome data suggest that less invasive surfactant administration (LISA) is safe. Results from the follow-up of the randomized controlled AMV (avoid mechanical ventilation) study.

    abstract::Less invasive surfactant administration (LISA) is a method to deliver surfactant to spontaneously breathing premature infants via a thin catheter. Here we report the two-year outcome from the AMV (avoid mechanical ventilation) study, the first randomized controlled trial on this mode of surfactant delivery. No statist...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Herting E,Kribs A,Härtel C,von der Wense A,Weller U,Hoehn T,Vochem M,Möller J,Wieg C,Roth B,Göpel W,German Neonatal Network (GNN).

    更新日期:2020-08-01 00:00:00

  • Plasma fibronectin concentrations in healthy newborns and in children.

    abstract::Plasma fibronectin (FN) concentrations were measured by an immunonephelometric method in cord blood from 76 healthy newborns (45 full term and 31 preterm), in 181 healthy children, from 1 month-15 years old, divided by age into seven groups and in 81 control adults. FN levels in newborns were 35% of those of adults. T...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Valletta EA,Bonazzi L,Zuanazzi R,Del Col G,Andreoli A,Stocchero L,Boner AL

    更新日期:1988-01-01 00:00:00

  • Rational diagnostic strategies for Lyme borreliosis in children and adolescents: recommendations by the Committee for Infectious Diseases and Vaccinations of the German Academy for Pediatrics and Adolescent Health.

    abstract::The varying clinical manifestations of Lyme borreliosis, transmitted by Ixodes ricinus and caused by Borrelia burgdorferi, frequently pose diagnostic problems. Diagnostic strategies vary between early and late disease manifestations and usually include serological methods. Erythema migrans is pathognomonic and does no...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,实务指引


    authors: Huppertz HI,Bartmann P,Heininger U,Fingerle V,Kinet M,Klein R,Korenke GC,Nentwich HJ,Committee for Infectious Diseases and Vaccinations of the German Academy for Pediatrics and Adolescent Health.

    更新日期:2012-11-01 00:00:00

  • Time course of nocturnal cough and wheezing in children with acute bronchitis monitored by lung sound analysis.

    abstract::Cough and wheezing are the predominant symptoms of acute bronchitis. Hitherto, the evaluation of respiratory symptoms was limited to subjective methods such as questionnaires. The main objective of this study was to objectively determine the time course of cough and wheezing in children with acute bronchitis. The impa...

    journal_title:European journal of pediatrics

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Koehler U,Hildebrandt O,Fischer P,Gross V,Sohrabi K,Timmesfeld N,Peter S,Urban C,Steiß JO,Koelsch S,Kerzel S,Weissflog A

    更新日期:2019-09-01 00:00:00

  • Early onset sepsis calculator implementation is associated with reduced healthcare utilization and financial costs in late preterm and term newborns.

    abstract::The neonatal early onset sepsis (EOS) calculator is a novel tool for antibiotic stewardship in newborns, associated with a reduction of empiric antibiotic treatment for suspected EOS. We studied if implementation of the EOS calculator results in less healthcare utilization and lower financial costs of suspected EOS. F...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Achten NB,Visser DH,Tromp E,Groot W,van Goudoever JB,Plötz FB

    更新日期:2020-05-01 00:00:00

  • Neurodevelopmental outcomes after moderate to severe neonatal hypoglycemia.

    abstract::The long-term consequences of transient neonatal hypoglycemia are sparsely studied. We performed a follow-up of a cohort of neonates with blood glucose recordings < 1.7 mmol/L (< 30 mg/dL), treated with > 2.5 mmol/L (> 45 mg/dL), compared with healthy siblings. Exclusion criteria were gestational age < 35 weeks, sever...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Rasmussen AH,Wehberg S,Pørtner F,Larsen AM,Filipsen K,Christesen HT

    更新日期:2020-12-01 00:00:00

  • Prevalence of complementary/alternative medicine for children: a systematic review.

    abstract:UNLABELLED:Complementary/alternative medicine (CAM) has become an important topic, not least because of its popularity with patients. This systematic review is aimed at summarising the data known about CAM use in paediatric populations. A thorough search strategy was designed to identify all surveys on the prevalence o...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,评审


    authors: Ernst E

    更新日期:1999-01-01 00:00:00

  • Intussusception in infants and children: feasibility of ambulatory management.

    abstract::To evaluate the ambulatory management of ileo-colic intussusception in infants and children, a retrospective study over 3 years of 113 children treated for ileo-colic intussusception in a paediatric emergency department was undertaken with the aim of shortening the length of stay. A total of 113 children aged 10 days ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Le Masne A,Lortat-Jacob S,Sayegh N,Sannier N,Brunelle F,Cheron G

    更新日期:1999-09-01 00:00:00

  • Septic arthritis of the hip by Fusobacterium necrophorum after tonsillectomy: a form of Lemierre syndrome?

    abstract:UNLABELLED:Lemierre syndrome used to be a complication of severe oropharyngeal infection with regional thrombophlebitis, septicaemia and septic metastatic infections caused by Fusobacterium necrophorum in the pre-antibiotic era. A case of septic arthritis of the hip caused by F. necrophorum as a complication of tonsill...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章


    authors: Beldman TF,Teunisse HA,Schouten TJ

    更新日期:1997-11-01 00:00:00