Abstract:
BACKGROUND:Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. CASE REPORT:We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions. CONCLUSION:Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.
journal_name
Balkan Med Jjournal_title
Balkan medical journalauthors
Resim S,Kadıoğlu A,Akman T,Bayrak AG,Efe Edoi
10.5152/balkanmedj.2012.107subject
Has Abstractpub_date
2013-06-01 00:00:00pages
250-2issue
2eissn
2146-3123issn
2146-3131pii
bmj-30-2-250journal_volume
30pub_type
杂志文章abstract:BACKGROUND:Pulmonary arterial hypertension secondary to untreated left-to-right shunt defects leads to increased pulmonary blood flow, endothelial dysfunction, increased pulmonary vascular resistance, vascular remodelling, neointimal and plexiform lesions. Some recent studies have shown that inflammation has an importa...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2014.13307
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:The choroid plexuses, which could secrete a number of neurotrophins, have recently been used in transplantation in central nervous system diseases. AIMS:To study the mechanism of nerve regeneration in the central nervous system by grafting choroid plexus tissues. STUDY DESIGN:Animal experimentation. METHO...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2013.8259
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To investigate possible mitochondrial DNA (mtDNA) mutations in patients with Leber's hereditary optic neuropathy (LHON) in order to provide a precise diagnosis and genetic counseling. MATERIAL AND METHODS:Between 1982 and 2007, ten patients were clinically diagnosed with LHON and six of these patients agreed...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2012.015
更新日期:2012-09-01 00:00:00
abstract:Background:The ideal prophylaxis duration for transrectal ultrasonography-guided prostate biopsy is incompletely defined. Aims:To compare the infectious complications of transrectal ultrasonography-guided prostate biopsy with and without extended antibiotic prophylaxis. The secondary aim was to evaluate the risk facto...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2018.0477
更新日期:2018-09-21 00:00:00
abstract:BACKGROUND:As the idea of stem cell technology in the treatment of sensorial hearing loss has emerged over the past decades, the need for in vivo models for related experiments has become explicit. One of the most common experimental models for inner ear stem cell delivery experiments is the Wistar albino rat. AIMS:To...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2016.0226
更新日期:2017-05-05 00:00:00
abstract::Aneurysms of the azygos vein are rare and can sometimes mimic a paratracheal or posterior mediastinal mass. It is important to confirm the diagnosis with radiologic tools before performing invasive procedures, which carry the risk of hemorrhage. Here, we present a case in a 79-year-old asymptomatic patient of an incre...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2012.095
更新日期:2013-03-01 00:00:00
abstract::Definitive radiotherapy plays a major role in the treatment of locally advanced non-small cell lung cancer (LA NSCLC). After the impact of RT dose for lung cancer was established, a number of trials were structured with the aim of better local control and overall survival by either dose escalation or shortening the to...
journal_title:Balkan medical journal
pub_type: 杂志文章,评审
doi:10.5152/balkanmedj.2014.14496
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Inflammatory myofibroblastic tumors are rare benign tumors that can mimic malignancy. Their precise aetiology is unknown. They are seen more frequently in childhood and the most common involvement is seen in the lungs. Primary inflammatory myofibroblastic tumors of the gallbladder are rather infrequent. The ...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2013.8263
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Haematopoietic stem cell transplantation is a curative treatment option for many haematological disorders. Infection following haematopoietic stem cell transplantation is one of the major causes of mortality. AIMS:To investigate the outcomes of early cessation of empirical antibiotic treatment per protocol ...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2016.0012
更新日期:2017-04-05 00:00:00
abstract:BACKGROUND:Young maternal age is variously defined in studies of its effect on obstetrics and perinatal outcomes. Also, pregnancy has been reported as the leading cause of death in adolescent girls in low- and middle-income countries. AIMS:The aim of the study was to evaluate whether young maternal age was associated ...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.150364
更新日期:2016-05-01 00:00:00
abstract:Background:In plastic surgery practice, fasciocutaneous single-perforator-pedicled propeller flap is a preferred procedure; however, its survival rate is below than expected, especially in flaps with a big rotation arc. When botulinum toxin-A is injected into the muscle tissue that the perforator pedicle is arisen, the...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.galenos.2019.2019.9.44
更新日期:2020-02-28 00:00:00
abstract:OBJECTIVE:We aimed to determine the safety and feasibility of general anaesthesia (GA) compared with local anaesthesia + Monitored Anaesthesia Care (LA+MAC) for One-Day Thyroid Surgery (ODTS); to assess patient and operator satisfaction with either of the anesthetic approaches. MATERIAL AND METHODS:We reviewed prospec...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2012.006
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Bloodstream infections (BSI) are frequently seen after solid organ transplantation. The incidence of bloodstream infections differs among the types of transplantation. The microbiological features and antimicrobial resistance patterns change from centre to centre. AIMS:To evaluate the incidence and spectrum...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2013.9256
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:We investigated whether determination IL-6, IL-8, IL-1beta and TNF-alpha at baseline, total protein C (PC) levels at time of admission and 48 hours after initiation could complement the Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system to identify patients with sepsis, severe sepsis or...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2011.016
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Implant-based breast reconstruction after mastectomy has recently been reported to be the preferred type of surgery among breast-specific surgeons and plastic surgeons. AIMS:To explore the significant clinicopathological factors associated with long-term outcome related to local recurrences of the nipple am...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2017.0029
更新日期:2018-01-20 00:00:00
abstract:BACKGROUND:Continuous ambulatory peritoneal dialysis is a successful treatment modality for patients with end-stage renal disease. Peritoneal fibrosis (PF) is the most critical complication of long-term peritoneal dialysis (PD). AIMS:In our study, we aimed to compare the effects of colchicine and sirolimus on PF induc...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.15183
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Recently, accumulated research has found that the expression of telomerase activity (TA) was associated with colorectal cancer (CRC) advancement, whereas the TA prognostic effect in CRC patients is still controversial. AIMS:To investigate relationships between TA and CRC clinicopathological parameters. STU...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.151182
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The aim of this prospective, randomized, double-blind study was to investigate the postoperative analgesic effects of levobupivacaine or tramadol infiltration administered prior to surgery in septorhinoplasty (SRP) or endoscopic sinus surgery (ESS). MATERIAL AND METHODS:Sixty ASA class I-III adult patients e...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2012.027
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Family history of premature atherosclerosis imposes a high risk to people. The relationship between atherosclerosis and gene polymorphisms of various biomarkers such as Endothelial Nitric Oxide Synthase (eNOS), C-Reactive Protein (CRP), and Interleukin-6 (IL-6) has shown in previous studies. AIMS:The major ...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.151190
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Acrylamide is a widespread substance having many areas of utilization. Besides, it also forms a part of high-temperature processed starchy foods. To date, numerous in vivo and in vitro studies have documented that acrylamide has toxic effects on various organ systems. AIMS:To determine the potential protect...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2017.0830
更新日期:2018-04-04 00:00:00
abstract:OBJECTIVE:Obstructive sleep apnea syndrome (OSAS) is associated with increased cardiovascular morbidity and mortality. We aimed to investigate the matrix metalloproteinase-9 (MMP-9) level and MMP-9 gene polymorphism in sleep apnea patients with or without cardiovascular disease. STUDY DESIGN:Case-control study. MATER...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2012.068
更新日期:2013-03-01 00:00:00
abstract:Background:Oral immunotherapy for cow’s milk allergy is an effective treatment option because of its ability to increase the threshold for clinical reactions. Aims:To present our experience of oral immunotherapy for cow’s milk allergy in the pediatric allergy outpatient clinic, and to evaluate the long-term efficacy o...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.galenos.2020.2020.1.140
更新日期:2020-10-23 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the ex-utero intrapartum therapy (EXIT) applied to 3 of the 7 cases with oropharyngeal or neck masses and review the indicators of the need for an EXIT procedure. CASE REPORT:Prenatal presentation, size and localization of the masses, existence of fetal hydrops and associ...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.150096
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Presacral teratomas are usually observed in the first two decades of life and have a 50-67% incidence of malignant transformation. Surgery is the treatment of choice. CASE REPORT:Here, we report the case of 24-year-old female with chronic urinary retention after surgery for a presacral teratoma. CONCLUSION...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2014.9449
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The present study proposes to analyze the results obtained after transhiatal esophagectomies (THE), from the perspective of an Eastern European surgical center with low esophageal resection volume (LV). AIMS:Our analysis, which to the authors' knowledge is the first of its kind in Romania, has the purpose o...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.15514
更新日期:2015-01-01 00:00:00
abstract::Morphologically congenital sensorineural hearing loss can be investigated under two categories. The majority of congenital hearing loss causes (80%) are membranous malformations. Here, the pathology involves inner ear hair cells. There is no gross bony abnormality and, therefore, in these cases high-resolution compute...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2017.0367
更新日期:2017-09-29 00:00:00
abstract:BACKGROUND:Suicide is frequently encountered in patients suffering from major depressive disorder (MDD). Since only a third of treated depressed patients are able to achieve remission, in the last few years, new theories have been proposed to better understand the mechanism of this illness. Our paper analyzes the inter...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2016.150842
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Bell's palsy is the most frequent cause of unilateral facial paralysis. Inflammation is thought to play an important role in the pathogenesis of Bell's palsy. AIMS:Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are simple and inexpensive tests which are indicative of inflammatio...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.15456
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:In Bulgaria, more than 20 autochthonous human parasitic infections have been described and some of them are widespread. Over 50 imported protozoan and helminthic infections represent diagnostic and therapeutic challenges and pose epidemiological risks due to the possibility of local transmission. AIMS:To es...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.4274/balkanmedj.2017.0167
更新日期:2018-01-20 00:00:00
abstract:BACKGROUND:Citalopram is a selective serotonin reuptake inhibitor that requires routine cardiac monitoring to prevent a toxic dose. Prolongation of the QT interval has been observed in acute citalopram poisoning. Our previous experimental study showed that citalopram may be lead to QT prolongation by stimulating adenos...
journal_title:Balkan medical journal
pub_type: 杂志文章
doi:10.5152/balkanmedj.2015.15932
更新日期:2015-07-01 00:00:00