Balanced chromosomal translocation of chromosomes 6 and 7: a rare male factor of spontaneous abortions.

Abstract:

BACKGROUND:Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. CASE REPORT:We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions. CONCLUSION:Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.

journal_name

Balkan Med J

journal_title

Balkan medical journal

authors

Resim S,Kadıoğlu A,Akman T,Bayrak AG,Efe E

doi

10.5152/balkanmedj.2012.107

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

250-2

issue

2

eissn

2146-3123

issn

2146-3131

pii

bmj-30-2-250

journal_volume

30

pub_type

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