Stiffness versus prestress relationship at subcellular length scale.

Abstract:

:Local intracellular variations of cell mechanical properties, which are essential for vital cellular functions, have not been well characterized and are poorly understood. Here, we used results from our previous biomechanical imaging study to obtain relationships between intracellular shear modulus and prestress. We found that the subcellular shear modulus vs. prestress relationships exhibited positive linear correlations, consistent with previously observed behaviors at the whole cell and tissue levels. This, in turn, suggests that the prestress may be a unifying factor that determines material properties of living matter at different length scales.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Canović EP,Seidl DT,Barbone PE,Smith ML,Stamenović D

doi

10.1016/j.jbiomech.2014.08.004

subject

Has Abstract

pub_date

2014-09-22 00:00:00

pages

3222-5

issue

12

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(14)00428-X

journal_volume

47

pub_type

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