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An increased flip angle in late phase Gd-EOB-DTPA MRI shows improved performance in bile duct visualization compared to T2w-MRCP.

Abstract：

OBJECTIVES:To estimate the additional value of an increased flip angle of 35° in late phase Gd-EOB-DTPA-enhanced magnetic resonance cholangiography, as compared to T2w-MRCP. METHODS:40 adult patients underwent Gd-EOB-DTPA enhanced MRI of the liver including a T2-weighted 3D TSE MRCP (T2w-MRCP) as well as a late phase T1-weighted THRIVE sequences applying a flip angle of 35° (fa35). Two experienced observers evaluated the images regarding the delineation of the different biliary regions using a three-point grading system. A five-point scale was applied to determine the readers' confidence in identifying anatomical variations of the biliary tree. ROI analysis was performed to compare the signal-to-noise (SNR) and contrast-to-noise (CNR) ratios. RESULTS:The quality for visualizing the biliary tree differed between T2w-MRCP and fa35 (p=<0.001). Late phase EOB-MRC was rated as good for delineating the entire biliary system, whereas T2w-MRCP received an overall poor rating. Especially the depiction of the intrahepatic bile ducts was estimated as problematic in T2w-MRCP. T2w-MRCP and fa35 revealed a discordant assessment of anatomical variations in 12.5% of the cases, comprising a generally higher confidence level for fa35 (4.0 ± 1.1 vs. 2.2 ± 1.2, p=<0.001). SNR proofed to be significantly higher in fa35 (p=<0.001), whereas T2w-MRCP revealed a significantly higher CNR (<0.001). CONCLUSIONS:Gd-EOB-DTPA enhanced magnetic resonance cholangiography acquired with a flip angle of 35° revealed a better diagnostic performance compared to T2w-MRCP and might be a valuable adjunct in assessing functional bile duct abnormalities.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Stelter L,Freyhardt P,Grieser C,Walter T,Geisel D,Baur A,Seehofer D,Denecke T

doi

10.1016/j.ejrad.2014.06.005

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

1723-7

issue

10

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(14)00305-2

journal_volume

83

pub_type

杂志文章

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