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Apparent diffusion coefficient values of the normal uterus: Interindividual variations during menstrual cycle.

Abstract：

OBJECTIVES:To assess the apparent diffusion coefficient (ADC) changes of the normal uterine zones among reproductive women during the menstrual cycle. METHODS:The study included 101 women of reproductive age, each with regular cycle and normal endometrium/myometrium, as proved on histopathology or MR imaging examination. Diffusion-weighted (DW) imaging was performed along the axial plane, using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 800s/mm(2). The mean and standard deviation of the ADC values of normal endometrium/myometrium were calculated for menstrual, proliferative and secretory phase. Analysis of variance followed by the least significant difference test was used for statistical analysis. RESULTS:The ADC values of the endometrium were different in the three phases of the menstrual cycle (menstrual phase: 1.25±0.27; proliferative phase: 1.39±0.20; secretory phase: 1.50±0.18) (F: 9.64, p: 0.00). Statistical significant difference was observed among all groups (p<0.05). The ADC values of the normal myometrium were different in the three phases of the menstrual cycle (menstrual phase: 1.91±0.35; proliferative phase: 1.72±0.27; secretory phase: 1.87±0.28) (F: 3.60, p: 0.03). Statistical significant difference was observed between menstrual and proliferative phase and between proliferative and secretory phase (p<0.05). No significant difference was noted between menstrual and secretory phase (p>0.05). CONCLUSIONS:A wide variation of ADC values of normal endometrium and myometrium is observed during different phases of the menstrual cycle.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Tsili AC,Argyropoulou MI,Tzarouchi L,Dalkalitsis N,Koliopoulos G,Paraskevaidis E,Tsampoulas K

doi

10.1016/j.ejrad.2011.04.057

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

1951-6

issue

8

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(11)00464-5

journal_volume

81

pub_type

杂志文章

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