Abstract:
OBJECTIVE:Interstitial lung diseases are associated with increased risk of lung cancer. The prevalence of ILA at diagnosis of advanced non-small-cell lung cancer (NSCLC) and its impact on overall survival (OS) remain to be investigated. MATERIALS AND METHOD:The study included 120 treatment-naïve stage IV NSCLC patients (53 males, 67 females). ILA was scored on CT prior to any systemic therapy using a 4-point scale [0=no evidence of ILA, 1=equivocal for ILA, 2=suspicious for ILA, 3=ILA] by a sequential reading method previously reported. ILA scores of 2 or 3 indicated the presence of ILA. RESULTS:ILA was present in 17 patients (14%) with advanced NSCLC prior to any treatment (score3: n=2, score2: n=15). These 17 patients were significantly older (median age: 69 vs. 63, p=0.04) and had a heavier smoking history (median: 40 vs. 15.5 pack-year, p=0.003) than those with ILA score 0 or 1. Higher ILA scores were associated with shorter OS (p=0.001). Median OS of the 17 patients with ILA was 7.2 months [95%CI: 2.9-9.4] compared to 14.8 months [95%CI: 11.1-18.4] in patients with ILA score 0 or 1 (p=0.002). In a multivariate model, the presence of ILA remained significant for increased risk for death (HR=2.09, p=0.028) after adjusting for first-line systemic therapy (chemotherapy, p<0.001; TKI, p<0.001; each compared to no therapy) and pack years of smoking (p=0.40). CONCLUSION:Radiographic ILA was present in 14% of treatment-naïve advanced NSCLC patients. Higher ILA scores were associated with shorter OS, indicating that ILA could be a marker of shorter survival in advanced NSCLC.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Nishino M,Cardarella S,Dahlberg SE,Araki T,Lydon C,Jackman DM,Rabin MS,Hatabu H,Johnson BEdoi
10.1016/j.ejrad.2015.01.021subject
Has Abstractpub_date
2015-05-01 00:00:00pages
998-1004issue
5eissn
0720-048Xissn
1872-7727pii
S0720-048X(15)00064-9journal_volume
84pub_type
杂志文章abstract::To determine if proton magnetic resonance spectroscopy (1H MRS) of thyroid carcinoma is feasible and to determine if 1H MRS spectra of malignant tumors differ from that of normal thyroid tissue. We performed 1H MRS at 1.5 T at echo-times (TE) 136 and 272 ms to examine eight patients with thyroid cancer (primary tumour...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2004.05.003
更新日期:2005-04-01 00:00:00
abstract:INTRODUCTION:Concerning the preoperative clinical diagnostic work-up of glioma patients, tumor heterogeneity challenges the oncological therapy. The current study assesses the performance of a multimodal imaging approach to differentiate between areas in malignant gliomas and to investigate the extent to which such a c...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.02.006
更新日期:2014-05-01 00:00:00
abstract::Chiari III malformation is an extremely rare condition, and is characterized by the hindbrain herniation into a low occipital or high cervical encephalocele together with the pathologic and imaging features of the Chiari II malformation. In this report, an unusual variant of the Chiari III malformation was diagnosed i...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00334-5
更新日期:2001-09-01 00:00:00
abstract::Research into the possibilities of AI in cardiac CT has been growing rapidly in the last decade. With the rise of publicly available databases and AI algorithms, many researchers and clinicians have started investigations into the use of AI in the clinical workflow. This review is a comprehensive overview on the types...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2020.108969
更新日期:2020-07-01 00:00:00
abstract::Automatic computer-assisted detection (auto-CAD) of significant coronary artery disease (CAD) in coronary computed tomography angiography (cCTA) has been shown to have relatively high accuracy. However, to date, scarce data are available regarding the performance of auto-CAD in the setting of acute chest pain. This st...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.01.017
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To evaluate the diagnostic efficacy of curved planar reformations along the duct (long-axis CPR) and series of reformations perpendicular to the duct (short-axis MPR) in evaluating T-factors of pancreaticobiliary malignancy. MATERIALS AND METHODS:Twenty-five patients with surgically proven pancreaticobiliary m...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.01.022
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To examine factors associated with one step surgery in case of non-palpable breast cancer. MATERIALS AND METHODS:Clinical data of 152 consecutively diagnosed patients with breast cancer were analyzed retrospectively. Preoperative diagnostic findings were divided in subgroups: mammographically visible mass/micr...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.02.033
更新日期:2007-12-01 00:00:00
abstract::The physics of bubbles and of their oscillations is extremely complex and attempts at its mathematical description are generally inaccessible. Yet some idea, in broad descriptive terms at least, is very helpful in understanding bubble phenomena of clinical interest. A brief attempt to provide such a description is giv...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(02)00023-2
更新日期:2002-03-01 00:00:00
abstract::Ultrasonography (US) is a readily available non-invasive tool useful for the detection of musculoskeletal and soft tissue masses. Although X-Ray is often the first imaging study for evaluating both bone and soft tissue lesions, and magnetic resonance imaging and computed tomography are mandatory in lesions staging, US...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2017.02.042
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To prospectively evaluate the diagnostic performance of 64-section multidetector computed tomography (MDCT) to detect significant coronary artery stenosis using conventional coronary angiography (CCA) as the reference standard. MATERIALS AND METHODS:Institutional Review Board approval and informed consent were...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2007.01.009
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To evaluate image quality (IQ) and radiation dose in cone-beam computed tomography (CBCT) of the ankle using a novel twin robotic X-ray system. METHOD:We examined 16 cadaveric ankles with standard-dose (FD) and low-dose (LD) protocols using the new system's CBCT mode. For comparison, we performed multi-slice C...
journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejrad.2019.108659
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:The purpose of our study is to test for: (a) correlation between the presence of a perifollicular T2-hypointense rim on MRI with the presence of perifollicular hemorrhage on histology; and (b) correlation between this finding and diminished ovarian viability after intra-operative detorsion. METHODS AND MATERIA...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.09.020
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To investigate basilar artery atherosclerotic plaque distribution characteristics in symptomatic patients using 3.0T high-resolution MRI. MATERIALS AND METHODS:Thirty-eight patients with recent ischemic strokes or transient ischemic attacks were included. Conventional angiographic luminal imaging of these pati...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.10.031
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:The purpose of our study was to compare signal characteristics and image qualities of MR imaging at 3.0T and 1.5T in patients with diffuse parenchymal liver disease. MATERIALS AND METHODS:25 consecutive patients with diffuse parenchymal liver disease underwent abdominal MR imaging at both 3.0T and 1.5T within ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.07.027
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To evaluate if computed tomography (CT) coronary calcium scoring is needed after detection of coronary calcifications on conventional chest radiographs. MATERIALS AND METHODS:One hundred and five patients (67 men; 57.2+/-12.8 years) with suspected coronary artery disease underwent conventional chest radiograph...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.10.016
更新日期:2009-03-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) is poised to make significant contributions to the study of neuropsychiatric illnesses. Whatever neural pathology attends such illnesses has proven subtle at best. By identifying predictable, regionally specific deficits in brain function, fMRI can suggest brain regions for...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(99)00048-0
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:Aim of the study was to evaluate if a whole-body magnetic resonance angiography (MRA) protocol meets the requirements to evaluate the donor and host site target vessels for planning of microvascular head and neck reconstructions. PATIENTS AND METHODS:In 20 patients, scheduled for reconstruction of the mandi...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.11.016
更新日期:2012-02-01 00:00:00
abstract::The radiographic film wastage and the different parameters affecting this wastage were analysed for a 9-week period at a 600-bed University Hospital. An overall reject rate of 7.6% was found. The different reasons for rejection were evaluated, while retake rate, relation between working experience of the personnel, am...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(91)90067-6
更新日期:1991-05-01 00:00:00
abstract:PURPOSE:Our study was aimed to assess the diagnostic value of MR cholangiopancreatography (MRCP) and MR imaging at 3 T device when evaluating biliary adverse events after liver transplantation. MATERIALS AND METHODS:A series of 384 MR examinations in 232 liver transplant subjects with suspected biliary complications (...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.07.009
更新日期:2018-09-01 00:00:00
abstract::In this study, we evaluated a large number of subjects using BOLD MRI to provide more information about oxygen metabolism in the normal function of transplanted kidneys and to distinguish acute graft rejection from normal function kidneys. This study included 122 subjects (20 volunteers, 72 patients with normal functi...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.02.041
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:To investigate whether the evaluation of multiple spectral regions can increase the diagnostic performance of 1H-MRS of the breast and reduce false positive findings. METHODS:93 patients (mean age 56 years, range 23-79) undergoing breast MRI for routine clinical indications on a 1.5T scanner were eligible f...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.04.014
更新日期:2017-07-01 00:00:00
abstract::The thoracic inlet is insufficiently investigated by conventional radiographic techniques. CT clearly demonstrates this area free of superimposition. Thorough knowledge of cross sectional anatomy is essential for CT interpretation. There is a wide spectrum of pathology involving the thoracic inlet because its visceral...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::The new American Thoracic Society/European Respiratory Society (ATS/ERS) update to the multidisciplinary classification of idiopathic interstitial pneumonias (IIPs) defines both rare IIPs and rare histologic patterns of IIPs. Although these diseases are rare, each has some distinguishing imaging and pathologic charact...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.11.032
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare the diagnostic accuracy of 64-slice CT with that of invasive angiography in the detection of graft and/or coronary angioplasty stenosis in children who had undergone coronary artery surgery. POPULATION AND METHODS:Fifteen consecutive children (8 male and 7 female; age...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2008.06.008
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To assess the effect of a breath-hold after forced expiration on the rate of pneumothorax after computed tomography (CT)-guided transthoracic needle biopsy of pulmonary lesions. MATERIALS AND METHODS:Between January 2008 and December 2011, percutaneous CT-guided lung biopsy was performed in 440 patients. Two h...
journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejrad.2012.09.013
更新日期:2013-01-01 00:00:00
abstract::A double curve catheter for the left axillary artery approach to aortofemoral, selective renal and visceral angiography is described. The catheter shape enables a fast and easy catheterization of the abdominal aorta. Up till now no complications have been encountered. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract:OBJECTIVE:To compare outcomes after imaging-guided transforaminal lumbar nerve root blocks in MRI confirmed symptomatic disc herniation patients with and without Modic changes (MC). METHODS:Consecutive adult patients with MRI confirmed symptomatic lumbar disc herniations and an imaging-guided lumbar nerve root block i...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.06.008
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To assess diaphragmatic motion during forced breathing in a health screening center cohort by time-resolved quantitative analysis using dynamic chest radiography and demonstrate the characteristics and associations with demographics and pulmonary function of participants. MATERIALS AND METHODS:This prospecti...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.01.034
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of sonography-guided percutaneous microwave ablation of intrahepatic primary cholangiocarcinoma. MATERIALS AND METHODS:From May 2006 to March 2010, 15 patients (11 men, 4 women; mean age, 57.4 years) with 24 histologically proven intrahepatic primary cholangiocarcinoma les...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.01.014
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:This prospective study aimed to investigate the correlation between two perfusion methods: arterial spin labeling (ASL) and dynamic contrast enhanced (DCE) technique in patients with nasopharyngeal carcinoma (NPC) and to optimize ASL protocol. MATERIALS AND METHODS:Forty-five newly diagnosed NPC patients under...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.09.034
更新日期:2018-11-01 00:00:00