Characterization and regulation of the resistance-nodulation-cell division-type multidrug efflux pumps MdtABC and MdtUVW from the fire blight pathogen Erwinia amylovora.

abstract：BACKGROUND:Generation of extended- spectrum β- lactamases is one of the major mechanisms by which clinical Klebsiella pneumoniae develop resistance to antibiotics. Combined antibiotics prove to be a relatively effective method of controlling such resistant strains. Some of Chinese herbal active ingredients are known to...

journal_title：BMC microbiology

authors： Cai W,Fu Y,Zhang W,Chen X,Zhao J,Song W,Li Y,Huang Y,Wu Z,Sun R,Dong C,Zhang F

更新日期：2016-08-08 00:00:00

abstract：BACKGROUND:Non typhoidal salmonellosis is one of the neglected zoonoses in most African countries. The use of sub-therapeutic doses of antibiotics as animal growth promoter enhances the emergence and dissemination of antimicrobial resistance in bacteria with food animal reservoirs and may also results in antibiotics re...

journal_title：BMC microbiology

authors： Adetoye A,Pinloche E,Adeniyi BA,Ayeni FA

更新日期：2018-08-30 00:00:00

abstract：BACKGROUND:Footrot and interdigital dermatitis are endemic infectious diseases in all sheep farming regions, impairing welfare and production. The development of efficacious vaccines against the primary causative pathogen has been hampered by the extensive antigenic diversity of Dichelobacter nodosus. Understanding the...

journal_title：BMC microbiology

authors： Davies PL,Blanchard AM,Staley CE,Bollard NJ,Coffey TJ,Tötemeyer S

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Chlamydia trachomatis, an obligate intracellular human pathogen, is the most prevalent bacterial sexually transmitted infection worldwide and a leading cause of preventable blindness. HtrA is a virulence and stress response periplasmic serine protease and molecular chaperone found in many bacteria. Recombina...

journal_title：BMC microbiology

authors： Huston WM,Theodoropoulos C,Mathews SA,Timms P

更新日期：2008-11-06 00:00:00

abstract：BACKGROUND:Mosquitoes are intermediate hosts for numerous disease causing organisms. Vector control is one of the most investigated strategy for the suppression of mosquito-borne diseases. Anopheles stephensi is one of the vectors of malaria parasite Plasmodium vivax. The parasite undergoes major developmental and matu...

journal_title：BMC microbiology

authors： Rani A,Sharma A,Rajagopal R,Adak T,Bhatnagar RK

更新日期：2009-05-19 00:00:00

abstract：BACKGROUND:Microorganisms are a large and diverse form of life. Many of them live in association with large multicellular organisms, developing symbiotic relations with the host and some have even evolved to form obligate endosymbiosis. All Carpenter ants (genus Camponotus) studied hitherto harbour primary endosymbioti...

journal_title：BMC microbiology

authors： de Souza DJ,Bézier A,Depoix D,Drezen JM,Lenoir A

更新日期：2009-02-06 00:00:00

abstract：BACKGROUND:The last step in the maturation process of the large subunit of [NiFe]-hydrogenases is a proteolytic cleavage of the C-terminal by a hydrogenase specific protease. Contrary to other accessory proteins these hydrogenase proteases are believed to be specific whereby one type of hydrogenases specific protease o...

journal_title：BMC microbiology

authors： Devine E,Holmqvist M,Stensjö K,Lindblad P

更新日期：2009-03-11 00:00:00

abstract：BACKGROUND:Comparative knowledge of microbiomes and resistomes across environmental interfaces between animal production systems and urban settings is lacking. In this study, we executed a comparative analysis of the microbiota and resistomes of metagenomes from cattle feces, catch basin water, manured agricultural soi...

journal_title：BMC microbiology

authors： Zaheer R,Lakin SM,Polo RO,Cook SR,Larney FJ,Morley PS,Booker CW,Hannon SJ,Van Domselaar G,Read RR,McAllister TA

更新日期：2019-08-27 00:00:00

abstract：BACKGROUND:It is unclear how DNA is packaged in a bacterial cell in the absence of nucleosomes. To investigate the initial level of DNA condensation in bacterial nucleoid we used in vivo DNA digestion coupled with high-throughput sequencing of the digestion-resistant fragments. To this end, we transformed E. coli cells...

journal_title：BMC microbiology

authors： Tolstorukov MY,Virnik K,Zhurkin VB,Adhya S

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Francisella tularensis is a fastidious, Gram-negative coccobacillus and is the causative agent of tularemia. To assess viability yet overcome lengthy incubation periods, a culture-based PCR method was used to detect early growth of the lowest possible number of F. tularensis cells. This method utilized a pre...

journal_title：BMC microbiology

authors： Buse HY,Morris BJ,Rice EW

更新日期：2020-03-25 00:00:00

abstract：BACKGROUND:Exposure of cells to environmental stress conditions can lead to the interruption of several intracellular processes, in particular those performed by macromolecular complexes such as the spliceosome. RESULTS:During nucleotide sequencing of cDNA libraries constructed using RNA isolated from B. emersonii cel...

journal_title：BMC microbiology

authors： Georg RC,Stefani RM,Gomes SL

更新日期：2009-10-29 00:00:00

abstract：BACKGROUND:Macrolides and lincosamides are two leading types of antibiotics commonly used in therapies. The study examines the differences in resistance to these antibiotics and their molecular bases in S. epidermidis as well as in rarely isolated species of coagulase-negative staphylococci such as S. hominis, S. haemo...

journal_title：BMC microbiology

authors： Szemraj M,Czekaj T,Kalisz J,Szewczyk EM

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:The KdpD/KdpE two-component system of Escherichia coli regulates expression of the kdpFABC operon encoding the high affinity K+ transport system KdpFABC. The input domain of KdpD comprises a domain that belongs to the family of universal stress proteins (Usp). It has been previously demonstrated that UspC bi...

journal_title：BMC microbiology

authors： Heermann R,Lippert ML,Jung K

更新日期：2009-07-09 00:00:00

abstract：BACKGROUND:The balanced synthesis of membrane phospholipids, fatty acids and cell wall constituents is a vital facet of bacterial physiology, but there is little known about the biochemical control points that coordinate these activities in Gram-positive bacteria. In Escherichia coli, the glycerol-phosphate acyltransfe...

journal_title：BMC microbiology

authors： Parsons JB,Yao J,Jackson P,Frank M,Rock CO

更新日期：2013-11-16 00:00:00

abstract：BACKGROUND:Sinorhizobium meliloti is an agriculturally important model symbiont. There is an ongoing need to update and improve its genome annotation. In this study, we used a high-throughput pyrosequencing approach to sequence the transcriptome of S. meliloti, and search for new bacterial genes missed in the previous ...

journal_title：BMC microbiology

authors： Mao C,Evans C,Jensen RV,Sobral BW

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:The gut comprises an essential barrier that protects both invertebrate and vertebrate animals from invasion by microorganisms. Disruption of the balanced relationship between indigenous gut microbiota and their host can result in gut bacteria eliciting host responses similar to those caused by invasive patho...

journal_title：BMC microbiology

authors： Broderick NA,Raffa KF,Handelsman J

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:Escherichia coli is a well-studied anaerobic bacteria which is able to regulate metabolic pathways depending on the type of sugar presented in the medium. We have studied the glucose-lactose shift in E. coli at the protein level using a recently developed mass spectrometry platform. METHOD:Cells were grown ...

journal_title：BMC microbiology

authors： Mostovenko E,Deelder AM,Palmblad M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Classical bacteriological characteristics of Salmonella enterica indicate that the members of this species are unable to utilize lactose as a carbon source. However, lactose-fermenting (Lac+) strains of several Salmonella serovars have been isolated from different foodborne outbreaks as well as different geo...

journal_title：BMC microbiology

authors： Leonard SR,Lacher DW,Lampel KA

更新日期：2015-08-25 00:00:00

abstract：BACKGROUND:Antimicrobial resistance is currently a major global issue. As the rate of emergence of antimicrobial resistance has superseded the rate of discovery and introduction of new effective drugs, the medical arsenal now is experiencing shortage of effective drugs to combat diseases, particularly against diseases ...

journal_title：BMC microbiology

authors： Teh CH,Nazni WA,Nurulhusna AH,Norazah A,Lee HL

更新日期：2017-02-16 00:00:00

abstract：BACKGROUND:Bacteria employ multiple mechanisms to control gene expression and react to their constantly changing environment. Bacterial growth in rich laboratory medium is a dynamic process in which bacteria utilize nutrients from simple to complex and change physical properties of the medium, as pH, during the process...

journal_title：BMC microbiology

authors： Sitkiewicz I,Musser JM

更新日期：2009-02-10 00:00:00

abstract：BACKGROUND:A major obstacle to industrial-scale astaxanthin production by the yeast Phaffia rhodozyma is the strong inhibitory effect of high glucose concentration on astaxanthin synthesis. We investigated, for the first time, the mechanism of the regulatory effect of high glucose (> 100 g/L) at the metabolite and tran...

journal_title：BMC microbiology

authors： Miao L,Chi S,Wu M,Liu Z,Li Y

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:Campylobacter jejuni is a leading foodborne pathogen worldwide. Despite the fastidious nature of C. jejuni growth, increasing numbers of human campylobacteriosis suggest that C. jejuni may possess unique mechanisms to survive under various stress conditions. C. jejuni possesses only three sigma factors (FliA...

journal_title：BMC microbiology

authors： Hwang S,Jeon B,Yun J,Ryu S

更新日期：2011-09-22 00:00:00

abstract：BACKGROUND:Several intracellular bacterial pathogens have evolved subtle strategies to subvert vesicular trafficking pathways of their host cells to avoid killing and to replicate inside the cells. Brucellae are Gram-negative facultative intracellular bacteria that are responsible for brucellosis, a worldwide extended ...

journal_title：BMC microbiology

authors： Hamer I,Goffin E,De Bolle X,Letesson JJ,Jadot M

更新日期：2014-09-02 00:00:00

abstract：ERRATUM:Upon publication of the original article (1) it was highlighted by the authors that a grant awarded to support the research work of the study was missed in the acknowledgements. It should also be acknowledged that the grant titled "Genotyping and Molecular Epidemiological Characteristic of Bacillus anthracis in...

journal_title：BMC microbiology

authors： Li S,Ma Q,Chen H,Wang D,Liu Y,Wei X,You L,Yao G,Tian K,Tang G

更新日期：2018-04-12 00:00:00

abstract：BACKGROUND:Total community rDNA was used to determine the diversity of bacteria and archaea from water, wet sediment and microbial mats samples of hot springs in the Eastern lowlands of Eritrea. The temperatures of the springs range from 49.5 °C to 100 °C while pH levels varied from 6.97 to 7.54. Akwar and Maiwooi have...

journal_title：BMC microbiology

authors： Ghilamicael AM,Budambula NLM,Anami SE,Mehari T,Boga HI

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:The catabolite control protein CcpA is a transcriptional regulator conserved in many Gram-positives, controlling the efficiency of glucose metabolism. Here we studied the role of Bacillus cereus ATCC 14579 CcpA in regulation of metabolic pathways and expression of enterotoxin genes by comparative transcripto...

journal_title：BMC microbiology

authors： van der Voort M,Kuipers OP,Buist G,de Vos WM,Abee T

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae has previously been characterized as a micro-organism that is genetically highly stable. In spite of this genetic stability, homologous DNA recombination has been hypothesized to lie at the basis of antigenic variation of the major surface protein, P1, of M. pneumoniae. In order to iden...

journal_title：BMC microbiology

authors： Sluijter M,Hoogenboezem T,Hartwig NG,Vink C

更新日期：2008-10-02 00:00:00

abstract：BACKGROUND:For a good probiotic candidate, the abilities to adhere to intestinal epithelium and to fortify barrier function are considered to be crucial for colonization and functionality of the strain. The strain Lactobacillus acidophilus LAB20 was isolated from the jejunum of a healthy dog, where it was found to be t...

journal_title：BMC microbiology

authors： Kainulainen V,Tang Y,Spillmann T,Kilpinen S,Reunanen J,Saris PE,Satokari R

更新日期：2015-01-16 00:00:00

abstract：BACKGROUND:Over the last years oleaginous yeasts have been studied for several energetic, oleochemical, medical and pharmaceutical purposes. However, only a small number of yeasts are known and have been deeply exploited. The search for new isolates with high oleaginous capacity becomes imperative, as well as the use o...

journal_title：BMC microbiology

authors： Miranda C,Bettencourt S,Pozdniakova T,Pereira J,Sampaio P,Franco-Duarte R,Pais C

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:The plasma membrane plays an essential role in selective permeability, compartmentalization, osmotic balance, and cellular uptake. The characteristics and functions of cyanobacterial membranes have been extensively investigated in recent years. Cell-penetrating peptides (CPPs) are special nanocarriers that c...

journal_title：BMC microbiology

authors： Liu BR,Huang YW,Lee HJ

更新日期：2013-03-14 00:00:00