Abstract:
BACKGROUND:Dual-energy absorptiometry (DXA) is the current reference standard for assessing pediatric osteoporosis; however due to its areal nature, it has limitations. Thus, quantitative ultrasound (QUS), a modality free of ionizing radiation, has been proposed as a potential surrogate for DXA. OBJECTIVE:To semi-quantitatively assess the diagnostic accuracy of QUS for evaluating pediatric osteoporosis according to the U.S. Preventive Services Task Force guidelines. MATERIALS AND METHODS:We retrieved articles on the diagnostic accuracy of quantitative US for assessing abnormal bone quality or quantity in patients of mean age ≤19 years from MEDLINE, EMBASE and Cochrane Library CCTR databases. Evidences were analyzed for reliability, construct and criterion validity, and responsiveness of quantitative US, according to the following questions: (1) How reliable is the acquisition of QUS measurements? (2) Is QUS diagnostically accurate to characterize bone strength and quality in osteoporotic children? (3) Is QUS sensitive to detect changes in bone status over time? (4) Is QUS able to predict future skeletal fractures/degeneration? Three reviewers independently evaluated the quality of reporting and methodological quality using the Standards for Reporting of Diagnostic Accuracy (STARD) and the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tools. RESULTS:Out of 262 retrieved references (215 unique), we included 28 studies (1,963 patients; 807 reported boys and 761 girls, others unspecified; reported mean age, 0-19 years). The mean quality of reporting score was "excellent" in 24/28 (86%) studies; 11/28 (39%) studies had "adequate" research design quality. CONCLUSION:There is no evidence of the diagnostic value of QUS at the present time despite the overall excellent and adequate research design quality of primary studies. Although QUS can produce reliable measurements, insufficient evidence has been reported to support other clinimetric properties of this technique.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Wang KC,Wang KC,Amirabadi A,Cheung E,Uleryk E,Moineddin R,Doria ASdoi
10.1007/s00247-014-3041-xsubject
Has Abstractpub_date
2014-12-01 00:00:00pages
1573-87issue
12eissn
0301-0449issn
1432-1998journal_volume
44pub_type
杂志文章,评审abstract::Perigraft seroma is a rare complication of synthetic vascular grafts. We describe a new sign observed in two children who underwent computed tomography of the chest for further evaluation of seromas complicating modified Blalock-Taussig procedures in which a polytetrafluoroethylene graft was used. In both patients con...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050141
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:Oral contrast preparation is fundamental to ensuring diagnostic examination quality for magnetic resonance enterography (MRE), yet little is known about the relative palatability and tolerability of various oral contrast agents in pediatric patients with known or suspected inflammatory bowel disease. OBJECT...
journal_title:Pediatric radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00247-019-04378-5
更新日期:2019-06-01 00:00:00
abstract::We present a 16-year-old boy with autoimmune liver disease and longstanding portal hypertension in whom a CT arteriogram demonstrated a large aneurysm arising from the distal, extra-parenchymal portion of the splenic artery. Because of its location adjacent to multiple venous collaterals, the aneurysm was indistinguis...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-009-1493-1
更新日期:2010-07-01 00:00:00
abstract::Atlas anomalies in terms of clefts and aplasia are rare. They can sometimes simulate fractures and need further evaluation. Imaging in terms of CT and MR can help resolve diagnostic confusion and also outline associated neurological involvement. A rare anomaly of anterior and posterior atlas arch, previously unclassif...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470100542
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Despite regulations, insufficient information is provided to adult patients prior to their radiologic examinations. Information regarding paediatric patients has not been systematically studied. OBJECTIVE:To survey parents' experience and wishes for information in connection with their child's radiographic ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-018-4300-z
更新日期:2019-02-01 00:00:00
abstract::Suspected appendicitis is the most common indication for emergent abdominal surgery in children. The clinical diagnosis of appendicitis can be challenging, and CT is playing an increasing role in the evaluation of right lower quadrant pain. Occasionally, alternative diagnoses to appendicitis can be suggested on CT. Th...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-008-1110-8
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Hirschsprung disease (HD) is a functional obstruction of the bowel caused by the absence of intrinsic enteric ganglion cells. The diagnosis of total colonic HD (TCHD) based on contrast enemas is difficult in newborns because radiological findings vary. OBJECTIVE:To evaluate the radiographic and contrast ene...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-008-0952-4
更新日期:2008-11-01 00:00:00
abstract::A 6-year-old boy developed progressive motor weakness and areflexia. The clinical picture, combined with electrophysiological findings, indicated a diagnosis of Guillain-Barré syndrome (GBS). MRI on admission revealed spinal cord swelling and increased signal intensity within the cord. It is concluded that, since a de...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050408
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Prader orchidometry has been the standard method for evaluating testicular size. As this technique is subjective and tends to overestimate the testicular volume, ultrasound (US) has been proposed as more reliable. OBJECTIVE:To evaluate the intra- and interobserver agreement of US measurements of testicular ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-018-4195-8
更新日期:2018-11-01 00:00:00
abstract::A case of vein of Galen aneurysm, studied with a fast gradient refocusing pulse MRI sequence, is presented. Fast MRI sequences allowed the acquisition of additional hemodynamic information that was not available with either routine MRI or angiography. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02013833
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Various skeletal muscle diseases result in fatty infiltration, making it important to develop noninvasive biomarkers to objectively measure muscular fat. OBJECTIVE:We compared T2 relaxation time mapping (T2 maps) and magnetic resonance spectroscopy (MRS) with physical characteristics previously correlated w...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2791-1
更新日期:2014-02-01 00:00:00
abstract::Kidney length (KL), renal area and renal parenchymal area were measured on i.v. urograms of 255 children without apparent kidney disease age 0 to 14 years. These parameters were compared with age, body height, body surface area and the distance between the 1st and 4th lumbar vertebral body. In addition, renal parenchy...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01464310
更新日期:1980-04-01 00:00:00
abstract::Calcification of the upper respiratory tract is exceptional in persons aged under 15 years, and only 9 cases have been published so far in the English or French literature. We present a new case and analyse those already reported. ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/BF02011495
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Conventional MRI sequences are often affected in neuropediatric imaging by unavoidable movements. Therefore, children younger than 6 years usually have to be examined under sedation/anesthesia. A new real-time MRI technique with automatic slice advancement allows for motion-robust T2-weighted volume coverage...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04771-5
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:The unicameral bone cyst (UBC) is a common cystic bone lesion seen in children. We review and summarize its MR findings, focusing on their appearance following contrast enhancement, and correlating them to known histologic features of UBC. SUBJECTS AND METHODS:A retrospective review of 20 cases (13 boys, 7 g...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000258
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Laterality defects are quite common in thoracoileopagus and parapagus dicephalus but rare in other types of conjoined twins. OBJECTIVE:To present the presumed laterality defects in cephalothoracoileopagus and prosopothoracoileopagus conjoined twins, based on the unilateral or bilateral absence or duplicatio...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2316-8
更新日期:2012-06-01 00:00:00
abstract::In 30 children with renal allografts the diagnostic validity of pulsed Doppler (PD) versus colour coded Doppler (CD) sonography was assessed prospectively. 46 PD examinations were performed calculating the resistive index (RI) in the segmental arteries in comparison to 46 CD scans, where renal blood flow throughout th...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012486
更新日期:1992-01-01 00:00:00
abstract::Common systemic disorders that cause cerebral venous thrombosis (CVT) in children include dehydration, trauma, infection and haematological diseases. No cause for CVT is identified in one quarter of all cases. We report a child with thalamic infarcts due to internal CVT who had congenital heterozygous protein-C defici...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050776
更新日期:2000-06-01 00:00:00
abstract::Seventy-five premature infants weighing between 600 and 3200 g were studied over a period of 1 year. All of the infants received surfactant therapy for hyaline membrane disease immediately after birth and, thereafter, up to four doses every 6 h. The roentgenographic findings in all patients were documented at birth an...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01372230
更新日期:1996-01-01 00:00:00
abstract::The technique of inversion-ligation appendectomy is used by some surgeons to eliminate the risk of peritoneal contamination as the result of incidental appendectomy during an otherwise clean surgical procedure. In most cases, the intussuscepted appendix necroses and sloughs into the cecum after several days. We presen...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470100492
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Influenza A (H1N1) can cause severe neurological complications. OBJECTIVE:The purpose of this study was to analyze clinical and MRI features of neurological complications after H1N1 infection in critically ill children. MATERIALS AND METHODS:We retrospectively analyzed clinical and neuroimaging findings in...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2682-5
更新日期:2013-09-01 00:00:00
abstract::Three newborns with thin ribs and thin long bones with multiple fractures are reported. Whereas one patient presents a syndromic association of bone dysplasia and intrauterine dwarfism two other patients cannot be appropriately evaluated due to lack of basic clinical and pathologic data. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388044
更新日期:1988-01-01 00:00:00
abstract::A marked thoracic deformity associated with intrathoracic tracheal narrowing was seen in a 17-year-old with achondroplasia and dyspnea. The role of chest deformity and its evaluation by CT and MRI in achondroplastic patients with respiratory symptoms are considered. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012508
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:In previous studies, typical radiological findings in the cervical spine of patients with diastrophic dysplasia (DD) have been kyphosis, displacement of the vertebrae, spina bifida occulta (SBO), anterior hypoplasia of vertebrae C3-5, and hyperplasia and dysmorphism of the odontoid process. OBJECTIVES:To ma...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-002-0720-9
更新日期:2002-09-01 00:00:00
abstract::Vasoactive intestinal polypeptide (VIP) secreting neural crest tumours are an uncommon but important treatable cause of intractable childhood diarrhoea. The radiological appearances of two cases are presented with a review of radiological findings in childhood VIP secreting neural crest tumours. Twenty eight cases of ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/BF02011377
更新日期:1990-01-01 00:00:00
abstract::Historically, the first case of congenital prepyloric membrane in an infant was documented in 1933 [1]. Since then cases have been reported only sporadically in the literature [2-8]. This is a case of congenital antral web which was identified by real-time ultrasonography, confirmed by barium meal study, and proven at...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02016251
更新日期:1992-01-01 00:00:00
abstract::Ureteral valves are an uncommon cause of upper urinary tract obstruction. The majority of cases are discovered only at surgery or autopsy. We report a case diagnosed by antegrade pyelography under sonographic guidance and we review the literature. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388420
更新日期:1988-01-01 00:00:00
abstract::We report a rare example of catastrophic antiphospholipid syndrome (CAPS) in a young child. A 3-year-old girl with no previous medical history presented with extensive and recurrent thromboses. The diagnosis of CAPS was based on the occurrence of cardiopulmonary embolism in the child with a high titre of autoantibodie...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-006-0183-5
更新日期:2006-08-01 00:00:00
abstract::Xanthogranulomatous pyelonephritis (XGP), a rare chronic renal infection in children, usually presents as high fever, pyuria and an abdominal mass. This child with clinical and radiologic evidence of osteomyelitis was not suspected of renal disease until a non-functioning kidney was discovered during a bone scan. The ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388099
更新日期:1987-01-01 00:00:00
abstract::Sporotrichosis in children is rare, and its osteoarticular form is very unusual. Disseminated forms are described mostly in immunocompromised patients. We report a case of a 5-year-old immunocompetent boy with multiple suppurated cutaneous lesions that progressed to polyarthritis of the hands and feet. Radiographic im...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-015-3299-7
更新日期:2015-08-01 00:00:00