Experimental validation of frequently-used echocardiographic right-ventricular impedance parameters.

Abstract:

BACKGROUND:Aim of the study was to validate commonly used bedside right-ventricular (RV) impedance parameters, which are utilized in determining heart-lung interactions during mechanical ventilation. METHODS:Fifteen pigs were equally assigned to either an open or a closed pericardium group. In all animals, an inflatable vascular occluder and a flow probe were placed around the main pulmonary artery, which allowed for a gradual increase in pulmonary vascular impedance with banding of the pulmonary artery. A median sternotomy was performed for the open pericardium group, and a lateral thoracotomy was performed for the closed pericardium group. RESULTS:In the open pericardium group, mean acceleration time (ACmean) and the slope of the pulmonary artery flow correlated significantly with Poiseuille resistance over the banding (r=0.67 and r=0.65, respectively). In the closed pericardium group, the ratio of the right to left ventricular area, eccentricity index, and tricuspid annular plane systolic excursion did not correlate with resistance over the banding, only the ACmean showed a significant correlation with resistance over the banding (r=0.88). CONCLUSION:ACmean is a reliable parameter of RV impedance that can be used to study the heart-lung interactions during mechanical ventilation.

journal_name

Minerva Anestesiol

journal_title

Minerva anestesiologica

authors

Reis Miranda D,Marco Knook AH,Paalvast F,Rossi A,Hop W,Oei F,Van Bommel J,Gommers D

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

1169-77

issue

11

eissn

0375-9393

issn

1827-1596

pii

R02Y9999N00A140861

journal_volume

80

pub_type

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