Abstract：
:We studied 10 consecutive, sedated and paralyzed patients with Acute Respiratory Distress Syndrome (ARDS). The entire study lasted 4 hours, divided in 3 periods: 2 hours of recommended ventilation [lung protective strategy, LPS, i.e., ventilation with low tidal volume (< 8 mL/kg), limiting the plateau at 35 cm H2O, together with high positive end-expiratory pressure (PEEP)], 1 hour of sigh (LPS with 3 consecutive sighs/min at 45 cm H2O plateau pressure), and 1 hour of LPS. Total minute ventilation, PEEP, FiO2 and mean airway pressure were kept constant. The introduction of sighs induced a consistent recruitment and PaO2 improvement, and a decrease in venous admixture and PaCO2. Interrupting sighs and resuming LPS led to a progressive derecruitment, and all the physiological variables returned to baseline. Derecruitment was higher in patients with higher PaCO2 and lower VA/Q ratio. We conclude that: 1) LPS alone does not provide full lung recruitment and best oxygenation in ARDS; 2) application of sigh may provide pressure enough to recruit and volume enough to prevent reabsorption atelectasis.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Pelosi P,Bottino N,Panigada M,Eccher G,Gattinoni Lkeywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
313-7issue
5eissn
0375-9393issn
1827-1596journal_volume
65pub_type
杂志文章,评审abstract：OBJECTIVE:To investigate the relationship between Therapeutic Intervention Scoring System (TISS), length of ICU stay and severity of illness. DESIGN:Prospective study lasting 1 year. SETTING:Two 4-bed surgical-medical ICU. PATIENTS:All consecutively ICU admitted patients. METHODS:Every day TISS of each patient duri...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:In severe sepsis, several studies, a recent meta--analysis and studies evaluating multifaceted strategies for quality improvement, have shown that bundled care can improve survival. Here, the effectiveness of treatments for severe sepsis included in the bundles was analyzed. Despite the observational design of the stu...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
abstract：:Pulmonary complications are a source of greater postoperative morbidity and mortality and longer hospital stays. Although many factors have been implicated as predictors, few models have been developed with the rigorous methodology required for clinically useful tools. In this article we attempt to describe what to lo...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-03-01 00:00:00
abstract：:Results obtained with Althesin as anaesthetic in 100 patient subjected to urological surgery are presented. The continuous perfusion of Althesin gave a level of stable and flexible anaesthesia that, like the return to consciousness, was particularly appreciated by aged patients. Stress is laid on the fact that the har...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：BACKGROUND:To compare the anaesthetic epidural effects of levobupivacaine plus fentanyl versus bupivacaine plus fentanyl in patients undergoing lower limb surgery. METHODS:A single blind, randomised, prospective, multicentre study was designed to compare both therapies. The study was conducted in 10 tertiary hospitals...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,多中心研究,随机对照试验
doi：
更新日期：2008-07-01 00:00:00
abstract：:Surgery is currently the treatment of choice for acutely ruptured aneurysms, representing an efficient option both in the short and long term. We believe that the endovascular option may be of help in high surgical-risk cases. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:The authors briefly discuss the advantages and limits of sedation in critically ill patients. They also focus the importance of an individualized sedative approach which provides pain relief and modulates stress response, allowing patients to be easily arousable and cooperative as necessary. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 评论,社论
doi：10.23736/S0375-9393.18.13260-3
更新日期：2019-04-01 00:00:00
abstract：:Various aspects of the critically ill patient sharing pain, physical distress, anxiety, environmental components, predispose him to develop some sleep disorders (SD). We studied 20 conscious patients, age 16-80 (mean 48.15 SD of mean +/- 25), undergoing ICU mean 14.3 days (SD of mean +/- 7.5), to evaluate SD rate and ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:This report takes into consideration the complications due to "body packers" cocaine absorption. In particular we report a clinical case in which severe dysrhythmias occurred. We think an early insertion of a pacemaker able to rid ectopic focus by overdriving is essential by comparison with an effective anti-dysrhythm...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND:The goal of this paper was to investigate the association between patterns of intracranial hypertension (IH) and outcomes, to describe the treatment of patients with different patterns of IH, and to examine whether IH is an independent predictor of mortality and unfavourable outcome, respectively. METHODS:A...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Surgical trauma inhibits cellular immunity. Dexmedetomidine produces opioid-sparing effect and an impact on immune response. METHODS:Eighty-six surgical patients were enrolled and received postoperative patient-controlled intravenous analgesia (PCIA) with either fentanyl alone (fentanyl group) or combined w...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14581-4
更新日期：2021-01-12 00:00:00
abstract：:This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.17.12016-X
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:The NOL index is based on multiparametric analysis of heart rate (HR), skin conductance, wave plethysmography, and their time derivative. The aim of this study was to evaluate the NOL to detect standardized nociceptive stimuli with various remifentanil dosages under general anesthesia. METHODS:A prospective...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.18.12720-9
更新日期：2018-10-01 00:00:00
abstract：:A prolonged electrocardiographic QTc interval may be unsafe during general anesthesia; thus successful anesthetic management in patients affected by congenital long QT syndrome include avoidance of any event that increases sympathetic activity and drugs that prolong QT interval. Propofol seems to have less effect on t...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：:Known for two centuries, positive pressure non invasive mechanical ventilation (VMNPP) has been widely applied in acute respiratory failure (IRA) only in the last ten years. The fact that VMNPP is able to improve gas exchange by avoiding endotracheal intubation and its complications is the most attractive aspect in bo...
journal_title：Minerva anestesiologica
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：2000-10-01 00:00:00
abstract：AIM:Pain resulting from nerve lesions is classically referred to as a ''burning pain''. Both the axonal damage and sensitization of unmyelinated C-fibres have been considered as the possible generators of this sensation. The aim of this study was to verify the hypothesis that hot-burning sensations are produced by the ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:The paper reports the case of a young male which was severely poisoned by anilyne shoe black. After a few hours, he was in a semicomatose state, accompanied by "very dark" arterial blood gases with oxygen tension in excess of 100 mmHg. Following the administration of intravenous methylene blue (2 mg/kg), methemoglobin...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1990-12-01 00:00:00
abstract：:The authors illustrate some relevant emerging topics in pediatric anesthesia. Endotracheal cuffed tubes have entered into routine clinical practice in younger patients. Concerns about tracheal stenosis were overcome when manufactures began to produce a new class of high volume, low pressure endotracheal tubes. Ultraso...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2009-04-01 00:00:00
abstract：:Critical ultrasound, apparently a recent field, is in fact the outcome of a slow process, initiated since 1946. The lung was traditionally not considered as part of ultrasound, yet we considered its inclusion as a priority in our definition of critical ultrasound. Acute respiratory failure is one of the most distressi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2009-05-01 00:00:00
abstract：:For several years now, the need for improving healthcare quality has determined the adoption of a businesslike philosophy in American hospitals, through quality control and improvement systems. In Italy, the introduction of this business concept in public healthcare is recent, while quality assurance is still widely i...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：:We studied haemostatic parameter and Antithrombin III (ATIII) level in 50 consecutive admissions for severe burns between 1990 to1994 to the Centro Grandi Ustionati Ospedale S. Eugenio, Rome. The criteria for inclusion in the study were age <16 years and the presence of major burns (extent of the burns >30 and second ...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:The introduction of use of propofol in the anesthetists' pharmacopoeia has reinvigorated the research for a totally intravenous anaesthesia, for which the Authors propose a diagram. However, in experience related to the supplementary use of N2O, in virtue of its analgesic power, demonstrates yet another utility, permi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:The performance of a precise and safe peripheral nerve blockade (PNB) can currently rely on the aid of the ultrasounds and nerve stimulators. The injection pressure monitoring may be beneficial to perform a safer procedure. This review focuses on the pressures measured during PNB among studies conducted on animal, and...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.19.13518-3
更新日期：2019-09-01 00:00:00
abstract：:Sepsis is a condition at high risk for the patients to develop organ(s) or system dysfunction/failure and represent a very limiting process for survival. Researchers and clinicians proposed standardization of terminology for sepsis and related problems to improve communication and to evaluate the efficacy of preventiv...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:Accidents during anaesthesia may be clinical or technical. To avoid the latter, stress is laid on the by no means new concept that techniques and handling must fit contingent requirements and that they may be dangerous as much for their inadequate as for their excessive use. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：UNLABELLED:The aim of this study is the comparison between the use of bupivacaine alone and a mixture of bupivacaine, mepivacaine and hyaluronidase in both retrobulbar and peribulbar blockades for eye surgery. Three hundred ninety-nine consecutive adult patients scheduled for cataract surgery with regional anaesthesia ...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-11-01 00:00:00
abstract：BACKGROUND:Blind insertion of endotracheal tubes through the intubating laryngeal mask airway (ILMA) is unsuccessful in almost 50% of cases on the first attempt, with an overall success rate of approximately 90%. We used a portable fiber optic device (Foley Airway Stylet Tool® FAST) to detect the reasons for failed int...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:The goal of the present work is to describe the development and results of the pediatric epidural analgesia program at the ''Hospital Nacional de Pediatria Prof. Dr. J. P. Garrahan'' in Argentina. METHODS:Patients with thoracotomy, abdominal surgery, osteotomy, amputations or severe trauma were included in ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate the use of laryngeal mask airway (LMA)® Protector™ by comparison with traditional LMA for performing endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). METHODS:This was a retrospective observational single-center study including 143 patients w...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.19.13328-7
更新日期：2019-07-01 00:00:00
