Co-modulated behavior and effects of differentially expressed miRNA in colorectal cancer.

abstract：BACKGROUND:Understanding the underlying genetic structure of human populations is of fundamental interest to both biological and social sciences. Advances in high-throughput genotyping technology have markedly improved our understanding of global patterns of human genetic variation. The most widely used methods for col...

journal_title：BMC genomics

authors： Maróti Z,Boldogkői Z,Tombácz D,Snyder M,Kalmár T

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:Parasitic wasps constitute one of the largest group of venomous animals. Although some physiological effects of their venoms are well documented, relatively little is known at the molecular level on the protein composition of these secretions. To identify the majority of the venom proteins of the endoparasit...

journal_title：BMC genomics

authors： Vincent B,Kaeslin M,Roth T,Heller M,Poulain J,Cousserans F,Schaller J,Poirié M,Lanzrein B,Drezen JM,Moreau SJ

更新日期：2010-12-07 00:00:00

abstract：BACKGROUND:Interactions among transcription factors (TFs) and histone modifications (HMs) play an important role in the precise regulation of gene expression. The context specificity of those interactions and further its dynamics in normal and disease remains largely unknown. Recent development in genomics technology e...

journal_title：BMC genomics

authors： Zhang L,Xue G,Liu J,Li Q,Wang Y

更新日期：2018-12-31 00:00:00

abstract：BACKGROUND:Two fifths of the world's population is at risk from dengue. The absence of effective drugs and vaccines leaves vector control as the primary intervention tool. Understanding dengue virus (DENV) host interactions is essential for the development of novel control strategies. The availability of genome sequenc...

journal_title：BMC genomics

authors： Guo X,Xu Y,Bian G,Pike AD,Xie Y,Xi Z

更新日期：2010-06-16 00:00:00

abstract：BACKGROUND:A high caloric diet, in conjunction with low levels of physical activity, promotes obesity. Many studies are available regarding the relation between dietary saturated fats and the etiology of obesity, but most focus on liver, muscle and white adipose tissue. Furthermore, the majority of transcriptomic studi...

journal_title：BMC genomics

authors： Nyima T,Müller M,Hooiveld GJ,Morine MJ,Scotti M

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:We use an approach based on Factor Analysis to analyze datasets generated for transcriptional profiling. The method groups samples into biologically relevant categories, and enables the identification of genes and pathways most significantly associated to each phenotypic group, while allowing for the partici...

journal_title：BMC genomics

authors： Lozano JJ,Soler M,Bermudo R,Abia D,Fernandez PL,Thomson TM,Ortiz AR

更新日期：2005-08-17 00:00:00

abstract：BACKGROUND:Meloidogyne chitwoodi commonly known as Columbia root-knot nematode or CRKN is one of the most devastating pests of potato in the Pacific Northwest of the United States of America. In addition to the roots, it infects potato tubers causing internal as well as external defects, thereby reducing the market val...

journal_title：BMC genomics

authors： Bali S,Vining K,Gleason C,Majtahedi H,Brown CR,Sathuvalli V

更新日期：2019-11-28 00:00:00

abstract：BACKGROUND:Ensifer alkalisoli YIC4027, a recently characterized nitrogen-fixing bacterium of the genus Ensifer, has been isolated from root nodules of the host plant Sesbania cannabina. This plant is widely used as green manure and for soil remediation. E. alkalisoli YIC4027 can grow in saline-alkaline soils and is a n...

journal_title：BMC genomics

authors： Dang X,Xie Z,Liu W,Sun Y,Liu X,Zhu Y,Staehelin C

更新日期：2019-08-12 00:00:00

abstract：BACKGROUND:Uranium (U) is a naturally occurring radionuclide that has been found in the aquatic environment due to anthropogenic activities. Exposure to U may pose risk to aquatic organisms due to its radiological and chemical toxicity. The present study aimed to characterize the chemical toxicity of U in Atlantic salm...

journal_title：BMC genomics

authors： Song Y,Salbu B,Teien HC,Sørlie Heier L,Rosseland BO,Høgåsen T,Tollefsen KE

更新日期：2014-08-20 00:00:00

abstract：BACKGROUND:There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases. East Coast fever, caused by the protist Theileria parva, kills one million cattle each year in sub-Saharan Africa, and contribu...

journal_title：BMC genomics

authors： Norling M,Bishop RP,Pelle R,Qi W,Henson S,Drábek EF,Tretina K,Odongo D,Mwaura S,Njoroge T,Bongcam-Rudloff E,Daubenberger CA,Silva JC

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:Despite significant efforts from the research community, an extensive portion of the proteins encoded by human genes lack an assigned cellular function. Most metazoan proteins are composed of structural and/or functional domains, of which many appear in multiple proteins. Once a domain is characterized in on...

journal_title：BMC genomics

authors： Kemmer D,Podowski RM,Arenillas D,Lim J,Hodges E,Roth P,Sonnhammer EL,Höög C,Wasserman WW

更新日期：2006-03-13 00:00:00

abstract：BACKGROUND:Litchi (Litchi chinensis Sonn.) is an economically important evergreen fruit tree widely cultivated in subtropical areas. Low temperature is absolutely required for floral induction of litchi, but its molecular mechanism is not fully understood. Leaves of litchi played a key role during floral induction and ...

journal_title：BMC genomics

authors： Zhang H,Shen J,Wei Y,Chen H

更新日期：2017-05-10 00:00:00

abstract：BACKGROUND:Sclerotinia sclerotiorum is a broad-host range necrotrophic pathogen which is the causative agent of Sclerotinia stem rot (SSR), and a major disease of soybean (Glycine max). A time course transcriptomic analysis was performed in both compatible and incompatible soybean lines to identify pathogenicity and de...

journal_title：BMC genomics

authors： Westrick NM,Ranjan A,Jain S,Grau CR,Smith DL,Kabbage M

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:HPA axis plays a major role in physiological homeostasis. It is also involved in stress and adaptive response to the environment. In farm animals in general and specifically in pigs, breeding strategies have highly favored production traits such as lean growth rate, feed efficiency and prolificacy at the cos...

journal_title：BMC genomics

authors： Sautron V,Terenina E,Gress L,Lippi Y,Billon Y,Larzul C,Liaubet L,Villa-Vialaneix N,Mormède P

更新日期：2015-11-17 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) and insertions/deletions (InDels) are the major genetic variations and are distributed extensively across the whole plant genome. However, few studies of these variations have been conducted in the long-lived perennial tea plant. RESULTS:In this study, we investigated ...

journal_title：BMC genomics

authors： Liu S,An Y,Tong W,Qin X,Samarina L,Guo R,Xia X,Wei C

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:One of the most fundamental and challenging tasks in bio-informatics is to identify related sequences and their hidden biological significance. The most popular and proven best practice method to accomplish this task is aligning multiple sequences together. However, multiple sequence alignment is a computing...

journal_title：BMC genomics

authors： Nguyen KD,Pan Y,Nong G

更新日期：2011-12-23 00:00:00

abstract：BACKGROUND:The importance of Indian germplasm as origin and primary center of diversity of cultivated melon is widely accepted. Genetic diversity of several collections from Indian has been studied previously, although an integrated analysis of these collections in a global diversity perspective has not been possible. ...

journal_title：BMC genomics

authors： Gonzalo MJ,Díaz A,Dhillon NPS,Reddy UK,Picó B,Monforte AJ

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:The hepatitis E virus (HEV) is the causative pathogen of hepatitis E, a global public health concern. HEV comprises 8 genotypes with a wide host range and geographic distribution. This study aims to determine the genetic factors influencing the molecular adaptive changes of HEV open reading frames (ORFs) and...

journal_title：BMC genomics

authors： Baha S,Behloul N,Liu Z,Wei W,Shi R,Meng J

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:Large amounts of mammalian protein-protein interaction (PPI) data have been generated and are available for public use. From a systems biology perspective, Proteins/genes interactions encode the key mechanisms distinguishing disease and health, and such mechanisms can be uncovered through network analysis. A...

journal_title：BMC genomics

authors： Ding Y,Chen M,Liu Z,Ding D,Ye Y,Zhang M,Kelly R,Guo L,Su Z,Harris SC,Qian F,Ge W,Fang H,Xu X,Tong W

更新日期：2012-07-20 00:00:00

abstract：BACKGROUND:Comparative genomics has emerged as a promising means of unravelling the molecular networks underlying complex traits such as drought tolerance. Here we assess the genotype-dependent component of the drought-induced transcriptome response in two poplar genotypes differing in drought tolerance. Drought-induce...

journal_title：BMC genomics

authors： Cohen D,Bogeat-Triboulot MB,Tisserant E,Balzergue S,Martin-Magniette ML,Lelandais G,Ningre N,Renou JP,Tamby JP,Le Thiec D,Hummel I

更新日期：2010-11-12 00:00:00

abstract：BACKGROUND:Sand fly saliva plays an important role in blood feeding and Leishmania transmission as it was shown to increase parasite virulence. On the other hand, immunity to salivary components impedes the establishment of infection. Therefore, it is most desirable to gain a deeper insight into the composition of sali...

journal_title：BMC genomics

authors： Hostomská J,Volfová V,Mu J,Garfield M,Rohousová I,Volf P,Valenzuela JG,Jochim RC

更新日期：2009-06-25 00:00:00

abstract：BACKGROUND:Citrus blight is a very important progressive decline disease of commercial citrus. The etiology is unknown, although the disease can be transmitted by root grafts, suggesting a viral etiology. Diagnosis is made by demonstrating physical blockage of xylem cells that prevents the movement of water. This test ...

journal_title：BMC genomics

authors： Fu S,Shao J,Roy A,Brlansky RH,Zhou C,Hartung JS

更新日期：2019-12-11 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a deadly disease with a five-year survival of less than 5%. A better understanding of the underlying biology may suggest novel therapeutic targets. Recent surveys of the pancreatic cancer genome have uncovered numerous new alterations; yet systematic functional characterization of candid...

journal_title：BMC genomics

authors： Shain AH,Salari K,Giacomini CP,Pollack JR

更新日期：2013-09-16 00:00:00

abstract：:After publication of [1], the authors were informed by John A. Rhodes of a counterexample to Theorem 11 of [1]. ...

journal_title：BMC genomics

authors： Nute M,Chou J,Molloy EK,Warnow T

更新日期：2020-02-10 00:00:00

abstract：BACKGROUND:Starvation not only affects the nutritional and health status of the animals, but also the microbial composition in the host's intestine. Next-generation sequencing provides a unique opportunity to explore gut microbial communities and their interactions with hosts. However, studies on gut microbiomes have b...

journal_title：BMC genomics

authors： Xia JH,Lin G,Fu GH,Wan ZY,Lee M,Wang L,Liu XJ,Yue GH

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:The AP2/ERF transcription factor, one of the largest gene families in plants, plays a crucial role in the regulation of growth and development, metabolism, and responses to biotic and abiotic stresses. Castor bean (Ricinus communis L., Euphobiaceae) is one of most important non-edible oilseed crops and its s...

journal_title：BMC genomics

authors： Xu W,Li F,Ling L,Liu A

更新日期：2013-11-13 00:00:00

abstract：BACKGROUND:Plant microRNAs (miRNAs) are involved in post-transcriptional regulatory mechanisms of several processes, including the response to biotic and abiotic stress, often contributing to the adaptive response of the plant to adverse conditions. In addition to conserved miRNAs, found in a wide range of plant specie...

journal_title：BMC genomics

authors： De Paola D,Cattonaro F,Pignone D,Sonnante G

更新日期：2012-01-24 00:00:00

abstract：BACKGROUND:Whilst being closely related to the model actinomycete Streptomyces coelicolor A3(2), S. lividans 66 differs from it in several significant and phenotypically observable ways, including antibiotic production. Previous comparative gene hybridization studies investigating such differences have used low-density...

journal_title：BMC genomics

authors： Lewis RA,Laing E,Allenby N,Bucca G,Brenner V,Harrison M,Kierzek AM,Smith CP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Improving fiber quality is a major challenge in cotton breeding, since the molecular basis of fiber quality traits is poorly understood. Fine mapping and candidate gene prediction of quantitative trait loci (QTL) controlling cotton fiber quality traits can help to elucidate the molecular basis of fiber quali...

journal_title：BMC genomics

authors： Liu D,Zhang J,Liu X,Wang W,Liu D,Teng Z,Fang X,Tan Z,Tang S,Yang J,Zhong J,Zhang Z

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:Intramuscular fat (IMF) is one of the most important factors positively associated with meat quality. Triglycerides (TGs), as the main component of IMF, play an essential role in muscle lipid metabolism. This transcriptome analysis of pectoralis muscle tissue aimed to identify functional genes and biological...

journal_title：BMC genomics

authors： Liu L,Liu X,Cui H,Liu R,Zhao G,Wen J

更新日期：2019-11-15 00:00:00