Characterization of genome-wide genetic variations between two varieties of tea plant (Camellia sinensis) and development of InDel markers for genetic research.

abstract：BACKGROUND:Both male and female pigeons have the ability to produce a nutrient solution in their crop for the nourishment of their young. The production of the nutrient solution has been likened to lactation in mammals, and hence the product has been called pigeon 'milk'. It has been shown that pigeon 'milk' is essenti...

journal_title：BMC genomics

authors： Gillespie MJ,Haring VR,McColl KA,Monaghan P,Donald JA,Nicholas KR,Moore RJ,Crowley TM

更新日期：2011-09-19 00:00:00

abstract：BACKGROUND:Genome-wide expression profiles are altered during biological aging and can describe molecular regulation of tissue degeneration. Age-regulated mRNA expression trends from cross-sectional studies could describe how aging progresses. We developed a novel statistical methodology to identify age-regulated expre...

journal_title：BMC genomics

authors： Gheorghe M,Snoeck M,Emmerich M,Bäck T,Goeman JJ,Raz V

更新日期：2014-02-14 00:00:00

abstract：BACKGROUND:Due to the advancement in high throughput technology, single nucleotide polymorphism (SNP) is routinely being incorporated along with phenotypic information into genetic evaluation. However, this approach often cannot achieve high accuracy for some complex traits. It is possible that SNP markers are not suff...

journal_title：BMC genomics

authors： Hay EHA,Utsunomiya YT,Xu L,Zhou Y,Neves HHR,Carvalheiro R,Bickhart DM,Ma L,Garcia JF,Liu GE

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Tandem mass spectrometry (MS/MS) has become a standard method for identification of proteins extracted from biological samples but the huge number and the noise contamination of MS/MS spectra obstruct swift and reliable computer-aided interpretation. Typically, a minor fraction of the spectra per sample (mos...

journal_title：BMC genomics

authors： Mujezinovic N,Schneider G,Wildpaner M,Mechtler K,Eisenhaber F

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:Excretory/secretory proteins (ESPs) play a major role in parasitic infection as they are present at the host-parasite interface and regulate host immune system. In case of parasitic helminths, transcriptomics has been used extensively to understand the molecular basis of parasitism and for developing novel t...

journal_title：BMC genomics

authors： Garg G,Ranganathan S

更新日期：2011-11-30 00:00:00

abstract：BACKGROUND:Association mapping approaches are dependent upon discovery and validation of single nucleotide polymorphisms (SNPs). To further association studies in Anopheles gambiae we conducted a major resequencing programme, primarily targeting regions within or close to candidate genes for insecticide resistance. RE...

journal_title：BMC genomics

authors： Wilding CS,Weetman D,Steen K,Donnelly MJ

更新日期：2009-07-16 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression by targeting specific mRNA species for degradation or interfering with translation. Specific miRNAs are key regulators of adipogenesis, and are expressed at different levels in adipose tissue from lean and obese mice. The deg...

journal_title：BMC genomics

authors： Link JC,Hasin-Brumshtein Y,Cantor RM,Chen X,Arnold AP,Lusis AJ,Reue K

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:The question of whether synonymous codon choice is affected by cellular tRNA abundance has been positively answered in many organisms. In some recent works, concerning the human genome, this relation has been studied, but no conclusive answers have been found. In the human genome, the variation in base compo...

journal_title：BMC genomics

authors： Kotlar D,Lavner Y

更新日期：2006-04-03 00:00:00

abstract：BACKGROUND:The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in the fusion of ETV6 (TEL) and RUNX1 (AML1) genes and defines a relatively uniform category, although only some patients suffer very late relapse. TEL/AM...

journal_title：BMC genomics

authors： Gandemer V,Rio AG,de Tayrac M,Sibut V,Mottier S,Ly Sunnaram B,Henry C,Monnier A,Berthou C,Le Gall E,Le Treut A,Schmitt C,Le Gall JY,Mosser J,Galibert MD

更新日期：2007-10-23 00:00:00

abstract：BACKGROUND:Drosophila melanogaster females show changes in behavior and physiology after mating that are thought to maximize the number of progeny resulting from the most recent copulation. Sperm and seminal fluid proteins induce post-mating changes in females, however, very little is known about the resulting gene exp...

journal_title：BMC genomics

authors： Dalton JE,Kacheria TS,Knott SR,Lebo MS,Nishitani A,Sanders LE,Stirling EJ,Winbush A,Arbeitman MN

更新日期：2010-10-06 00:00:00

abstract：BACKGROUND:Toxoplasmosis is caused by the apicomplexan parasite Toxoplasma gondii and can be acquired either congenitally or via the oral route. In the latter case, transmission is mediated by two distinct invasive stages, i.e., bradyzoites residing in tissue cysts or sporozoites contained in environmentally resistant ...

journal_title：BMC genomics

authors： Possenti A,Fratini F,Fantozzi L,Pozio E,Dubey JP,Ponzi M,Pizzi E,Spano F

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:Electron microscopy analyses of replicating chloroplast molecules earlier predicted bidirectional Cairns replication as the prevalent mechanism, perhaps followed by rounds of a rolling circle mechanism. This standard model is being challenged by the recent proposition of homologous recombination-mediated rep...

journal_title：BMC genomics

authors： Krishnan NM,Rao BJ

更新日期：2009-05-20 00:00:00

abstract：BACKGROUND:The sacred lotus (Nelumbo nucifera) is widely cultivated in China for its edible rhizomes and seeds. Traditional plant breeding methods have been used to breed cultivars with increased yields and quality of rhizomes and seeds with limited success. Currently, the available genetic maps and molecular markers i...

journal_title：BMC genomics

authors： Liu Z,Zhu H,Liu Y,Kuang J,Zhou K,Liang F,Liu Z,Wang D,Ke W

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis remains poorly understood. Here we provide a high-resolution transcriptome of Plasmodium falciparum as i...

journal_title：BMC genomics

authors： van Biljon R,van Wyk R,Painter HJ,Orchard L,Reader J,Niemand J,Llinás M,Birkholtz LM

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Many gram-negative bacteria use type III secretion systems (T3SSs) to translocate effector proteins into host cells. T3SS effectors can give some bacteria a competitive edge over others within the same environment and can help bacteria to invade the host cells and allow them to multiply rapidly within the ho...

journal_title：BMC genomics

authors： Hobbs CK,Porter VL,Stow ML,Siame BA,Tsang HH,Leung KY

更新日期：2016-12-19 00:00:00

abstract：BACKGROUND:Paired-tag sequencing approaches are commonly used for the analysis of genome structure. However, mammalian genomes have a complex organization with a variety of repetitive elements that complicate comprehensive genome-wide analyses. RESULTS:Here, we systematically assessed the utility of paired-end and mat...

journal_title：BMC genomics

authors： van Heesch S,Kloosterman WP,Lansu N,Ruzius FP,Levandowsky E,Lee CC,Zhou S,Goldstein S,Schwartz DC,Harkins TT,Guryev V,Cuppen E

更新日期：2013-04-16 00:00:00

abstract：BACKGROUND:Salinity is an abiotic stress that negatively affects soybean [Glycine max (L.) Merr.] seed yield. Although a major gene for salt tolerance was identified and consistently mapped to chromosome (Chr.) 3 by linkage mapping studies, it does not fully explain genetic variability for tolerance in soybean germplas...

journal_title：BMC genomics

authors： Do TD,Vuong TD,Dunn D,Clubb M,Valliyodan B,Patil G,Chen P,Xu D,Nguyen HT,Shannon JG

更新日期：2019-04-25 00:00:00

abstract：BACKGROUND:Even though microsatellite loci frequently have been isolated using recently developed next-generation sequencing (NGS) techniques, this task is still difficult because of the subsequent polymorphism screening requires a substantial amount of time. Selecting appropriate polymorphic microsatellites is a criti...

journal_title：BMC genomics

authors： Xia Y,Luo W,Yuan S,Zheng Y,Zeng X

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:Using the piggyBac-mediated GAL4/UAS transgenic system established in the silkworm, Bombyx mori, we have previously reported that overexpression of the Ras1(CA) oncogene specifically in the posterior silk gland (PSG) improved cell growth, fibroin synthesis, and thus silk yield. However, the detailed molecula...

journal_title：BMC genomics

authors： Ma L,Ma Q,Li X,Cheng L,Li K,Li S

更新日期：2014-03-09 00:00:00

abstract：BACKGROUND:Soybean cyst nematode (SCN) is the most economically devastating pathogen of soybean. Two resistance loci, Rhg1 and Rhg4 primarily contribute resistance to SCN race 3 in soybean. Peking and PI 88788 are the two major sources of SCN resistance with Peking requiring both Rhg1 and Rhg4 alleles and PI 88788 only...

journal_title：BMC genomics

authors： Shi Z,Liu S,Noe J,Arelli P,Meksem K,Li Z

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:The identification of genetic markers associated with complex traits that are expensive to record such as feed intake or feed efficiency would allow these traits to be included in selection programs. To identify large-effect QTL, we performed a series of genome-wide association studies and functional analyse...

journal_title：BMC genomics

authors： Saatchi M,Beever JE,Decker JE,Faulkner DB,Freetly HC,Hansen SL,Yampara-Iquise H,Johnson KA,Kachman SD,Kerley MS,Kim J,Loy DD,Marques E,Neibergs HL,Pollak EJ,Schnabel RD,Seabury CM,Shike DW,Snelling WM,Spangler ML,

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:Membrane proteins constitute up to 30% of the human proteome. These proteins have special properties because the transmembrane segments are embedded into lipid bilayer while extramembranous parts are in different environments. Membrane proteins have several functions and are involved in numerous diseases. A ...

journal_title：BMC genomics

authors： Orioli T,Vihinen M

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Transposable elements (TEs) are mobile genetic sequences that randomly propagate within their host's genome. This mobility has the potential to affect gene transcription and cause disease. However, TEs are technically challenging to identify, which complicates efforts to assess the impact of TE insertions on...

journal_title：BMC genomics

authors： Kvikstad EM,Piazza P,Taylor JC,Lunter G

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The 2009 pandemic H1N1 influenza virus emerged in swine and quickly became a major global health threat. In mouse, non human primate, and swine infection models, the pH1N1 virus efficiently replicates in the lung and induces pro-inflammatory host responses; however, whether similar or different cellular path...

journal_title：BMC genomics

authors： Go JT,Belisle SE,Tchitchek N,Tumpey TM,Ma W,Richt JA,Safronetz D,Feldmann H,Katze MG

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Nicotiana benthamiana is a widely used model plant species for research on plant-pathogen interactions as well as other areas of plant science. It can be easily transformed or agroinfiltrated, therefore it is commonly used in studies requiring protein localization, interaction, or plant-based systems for pro...

journal_title：BMC genomics

authors： Baksa I,Nagy T,Barta E,Havelda Z,Várallyay É,Silhavy D,Burgyán J,Szittya G

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Oral squamous cell carcinoma (OSCC) is one of the most common forms of cancer associated with the presence of precancerous oral leukoplakia. Given the poor prognosis associated with oral leukoplakia, and the difficulties in distinguishing it from cancer lesions, there is an urgent need to elucidate the molec...

journal_title：BMC genomics

authors： Wang Z,Feng X,Liu X,Jiang L,Zeng X,Ji N,Li J,Li L,Chen Q

更新日期：2009-08-19 00:00:00

abstract：BACKGROUND:Pantoea spp. are frequently isolated from a wide range of ecological niches and have various biological roles, as plant epi- or endophytes, biocontrol agents, plant-growth promoters or as pathogens of both plant and animal hosts. This suggests that members of this genus have undergone extensive genotypic div...

journal_title：BMC genomics

authors： De Maayer P,Chan WY,Blom J,Venter SN,Duffy B,Smits TH,Coutinho TA

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Intensive research based on the inverse expression relationship has been undertaken to discover the miRNA-mRNA regulatory modules involved in the infection of Hepatitis C virus (HCV), the leading cause of chronic liver diseases. However, biological studies in other fields have found that inverse expression r...

journal_title：BMC genomics

authors： Song R,Liu Q,Liu T,Li J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Though glioblastoma multiforme (GBM) is the most frequently occurring brain malignancy in adults, clinical treatment still faces challenges due to poor prognoses and tumor relapses. Recently, microRNAs (miRNAs) have been extensively used with the aim of developing accurate molecular therapies, because of the...

journal_title：BMC genomics

authors： Yerukala Sathipati S,Huang HL,Ho SY

更新日期：2016-12-22 00:00:00

abstract：BACKGROUND:The bacterial CRISPR system is fast becoming the most popular genetic and epigenetic engineering tool due to its universal applicability and adaptability. The desire to deploy CRISPR-based methods in a large variety of species and contexts has created an urgent need for the development of easy, time- and cos...

journal_title：BMC genomics

authors： Köferle A,Worf K,Breunig C,Baumann V,Herrero J,Wiesbeck M,Hutter LH,Götz M,Fuchs C,Beck S,Stricker SH

更新日期：2016-11-14 00:00:00