当前位置： SCI文献检索 > CLINICAL NEUROLOGY AND NEUROSURGERY期刊下所有文献 > High long-term symptomatic recurrence rates after Chiari-1 decompression without dural opening: a single center experience.

High long-term symptomatic recurrence rates after Chiari-1 decompression without dural opening: a single center experience.

Abstract：

OBJECTIVE:We evaluated long-term outcomes of posterior fossa decompression (PFD) without duroplasty in consecutive patients with newly diagnosed Chiari-1 malformation. METHODS:We searched the institutional database for all adult patients who underwent Chiari decompression between 1995 and 2007. PFD was offered to all consecutive patients with Chairi-1 malformation during this time period. We excluded patients who underwent re-exploration after initial Chiari-1 decompression elsewhere. Besides the demographic variables, presenting symptoms, neurological and radiographic findings the clinical records were studied for long-term outcomes specifically symptomatic improvement. We defined symptomatic improvement as resolution of all presenting symptoms including pain and/or neurological deficits at the last follow-up. The factors associated with symptom recurrence were also analyzed. RESULTS:We identified 47 patients who underwent PFD for Chiari-1 malformation. Syringomyelia was noted in 36.2% of patients and the mean tonsilar herniation was 12.6mm. At a mean follow-up of 9.3 years, the symptomatic improvement rate was 60.6%. There were no operative complications. Repeat posterior fossa decompression was required for 31.9% patients with symptomatic recurrence at an average of 2.6 years after initial decompression. Fibrotic thickening overlying the dura mater was observed in one-third of these patients. CONCLUSIONS:This case series reports low complication but high long-term symptomatic recurrence rates adults with symptomatic Chiari-1 malformation undergoing PFD.

journal_name

Clin Neurol Neurosurg

journal_title

Clinical neurology and neurosurgery

authors

Krishna V,McLawhorn M,Kosnik-Infinger L,Patel S

doi

10.1016/j.clineuro.2013.12.016

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

53-8

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(13)00525-8

journal_volume

118

pub_type

杂志文章

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