当前位置： SCI文献检索 > CLINICAL NEUROLOGY AND NEUROSURGERY期刊下所有文献 > Diagnosis of tuberculosis infection based on synthetic peptides from Mycobacterium tuberculosis antigen 85 complex.

Diagnosis of tuberculosis infection based on synthetic peptides from Mycobacterium tuberculosis antigen 85 complex.

Abstract：

AIM:The laboratory diagnosis of pulmonary tuberculosis (TB) and tuberculous meningitis (TBM) is particularly challenging. The aim of the present work is to develop an immunoassay for the diagnosis of TB infection, using synthetic peptides of antigen (Ag) 85 complex of M. tuberculosis (Mtb) H37Rv. METHODS:Four peptides (7-10 amino acids long) corresponding to group-specific epitopes of Ag 85 complex of Mtb were synthesized. All peptides were evaluated by enzyme-linked immunosorbent assay (ELISA) for immunoreactivity with sera and CSF samples of TB and TBM patients respectively. The diagnostic value of the four peptides was evaluated in both the samples. RESULTS:It was observed that Ag 85 peptide 1, 3 and 4 had the highest positive rates in the pulmonary patients; however, Ag 85 peptide 1 and 2 had shown good positivity in the TBM subjects. CONCLUSIONS:The synthetic peptide based ELISA using Ag 85 complex peptides is a sensitive, specific, rapid and cost effective immunoassay for early diagnosis of pulmonary and extrapulmonary TB. In addition, these synthetic peptides are comparatively easy to produce in a reproducible manner compared with the whole antigen.

journal_name

Clin Neurol Neurosurg

journal_title

Clinical neurology and neurosurgery

authors

Kashyap RS,Shekhawat SD,Nayak AR,Purohit HJ,Taori GM,Daginawala HF

doi

10.1016/j.clineuro.2012.07.031

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

678-83

issue

6

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(12)00423-4

journal_volume

115

pub_type

杂志文章

相关文献

CLINICAL NEUROLOGY AND NEUROSURGERY文献大全
  • Can vascular risk factors influence number and size of cerebral metastases? A 3D-MRI study in patients with different tumor entities.

    abstract：OBJECTIVE:There is increasing evidence that cerebral microangiopathy reduces number of brain metastases. Aim of this study was to analyse if vascular risk factors (arterial hypertension, diabetes mellitus, smoking, and hypercholesterolemia) or the presence of peripheral arterial occlusive disease (PAOD) can have an imp...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2018.01.001

    authors： Nagel S,Berk BA,Kortmann RD,Hoffmann KT,Seidel C

    更新日期：2018-02-01 00:00:00

  • Growth hormone and insulin growth factor-I levels in plasma and cerebrospinal fluid of patients with multiple sclerosis.

    abstract：:Multiple sclerosis (MS) has several clinically different forms. Whereas the illness progresses slowly in most of the patients, 10% have an aggressively progressive course with fatal outcome without signs of remyelination capability. The process of remyelination depends on numerous interactive factors, including the pr...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2005.11.014

    authors： Poljakovic Z,Zurak N,Brinar V,Korsic M,Basic S,Hajnsek S

    更新日期：2006-03-01 00:00:00

  • Risk factors for cranial nerve deficits during carotid endarterectomy: a retrospective study.

    abstract：BACKGROUND:Cranial nerve deficits during CEA are a known complication. The purpose of this study is to evaluate if significant changes in somatosensory evoked potentials and electroencephalography increase cranial nerve deficits during CEA. PROCEDURES:This is an observational retrospective case-control study analyzed ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2014.12.017

    authors： Thirumala PD,Kumar H,Bertolet M,Habeych ME,Crammond DJ,Balzer JR

    更新日期：2015-03-01 00:00:00

  • Butterfly vertebra.

    abstract：:A patient with a so-called 'butterfly vertebra' is presented. Radiography, including computed tomography, is shown. The embryology and pathogenesis of the vertebral column with respect to vertebral abnormalities are discussed, with special reference to butterfly vertebra. Finally, attention is paid to the clinical man...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/0303-8467(82)90039-7

    authors： de Graaf RJ,Matricali B,Hamburger HL

    更新日期：1982-01-01 00:00:00

  • Tacrolimus-related polyneuropathy: case report and review of the literature.

    abstract：:Patients, in particular recipients of orthotopic liver transplants, receiving the immunosuppressant tacrolimus (FK-506), are at risk for developing central neurotoxic adverse events. We report the occurrence of a tacrolimus-induced peripheral neurotoxic event, i.e. pure motor axonal polyneuropathy of the lower limbs i...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2007.10.014

    authors： De Weerdt A,Claeys KG,De Jonghe P,Ysebaert D,Chapelle T,Roeyen G,Jorens PG

    更新日期：2008-03-01 00:00:00

  • Neurologic symptoms and diagnosis in adults with mast cell disease.

    abstract：OBJECTIVE:To identify complications of mastocytosis that impact the nervous system across a large cohort. PATIENTS AND METHODS:In this retrospective series, we reviewed the electronic medical records of adult patients with a diagnosis of mastocytosis who were referred to a Neurologist at Mayo Clinic in Rochester, MN f...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2011.05.002

    authors： Smith JH,Butterfield JH,Pardanani A,DeLuca GC,Cutrer FM

    更新日期：2011-09-01 00:00:00

  • Different Aspects on Clinical Presentation of Developmental Venous Anomalies: Are They as Benign as Known? A Single Center Experience.

    abstract：BACKGROUND:Cerebral developmental venous anomalies (DVAs) are frequently diagnosed incidentally owing to the advances in neuroimaging. They are regarded as clinically insignificant due to their supposed quiescent existence which the authors aimed to contradict in this paper. AIM:In the aim of constituting a better und...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2020.106443

    authors： Kurt G,Aslan A,Kara E,Erol G,Şahin MB,Uçar M

    更新日期：2020-12-18 00:00:00

  • Patient acceptance of awake craniotomy.

    abstract：OBJECTIVES:The aim of this study was to objectively assess the patients' acceptance for awake craniotomy in a group of neurosurgical patients, who underwent this procedure for removal of lesions in or close to eloquent brain areas. PATIENTS AND METHODS:Patients acceptance for awake craniotomy under local anesthesia an...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2011.06.010

    authors： Wrede KH,Stieglitz LH,Fiferna A,Karst M,Gerganov VM,Samii M,von Gösseln HH,Lüdemann WO

    更新日期：2011-12-01 00:00:00

  • Syndrome of continuous muscle fibre activity confined to the legs.

    abstract：:We report a 35-year-old woman with painful muscle cramps in both legs, this being the only symptom of the syndrome of continuous muscle fibre activity. Diagnosis was confirmed by electromyography during sleep. ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/0303-8467(90)90035-4

    authors： de Waal M,Bertelsmann FW,Strijers RL

    更新日期：1990-01-01 00:00:00

  • Cerebral embolism during elective carotid endarterectomy treated with tissue plasminogen activator: utility of intraoperative EEG monitoring.

    abstract：:Electroencephalography (EEG) is routinely used during elective carotid endarterectomy (CEA) for monitoring cerebral perfusion. The period most frequently associated with cerebral hypoperfusion is the one during the clamping of the carotid artery. We present a case whereby acute hypoperfusion, as detected by ipsilatera...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2010.01.009

    authors： Michaelides C,Nguyen TN,Chiappa KH,Kwolek CJ,Simon MV

    更新日期：2010-06-01 00:00:00

  • The quality of life of patients after a lumbar microdiscectomy: a four-year monitoring study.

    abstract：INTRODUCTION/AIM:Health-conditioned quality of patients' life is equally a result of their subjective perception of the disease and their objective condition. The aim of this paper is to evaluate the quality of life of surgically treated lumbar radiculopathy patients by using a generic and a lumbar disease-specific que...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2010.03.014

    authors： Bosković K,Cigić T,Grajić M,Todorović-Tomasević S,Knezević A

    更新日期：2010-09-01 00:00:00

  • Progressive dementia, without cerebral hemorrhage, in a patient with hereditary cerebral amyloid angiopathy.

    abstract：:A now 58-year-old female patient, carrier of the point-mutation in the beta-amyloid gene on chromosome 21 which causes hereditary cerebral hemorrhage with amyloidosis - Dutch type, developed progressive dementia after the age of 55 years. She never suffered from a cerebral hemorrhage. Dementia has been described as a ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/0303-8467(92)90181-2

    authors： Haan J,Bakker E,Jennekens-Schinkel A,Roos RA

    更新日期：1992-01-01 00:00:00

  • Rhinorrhoea as the presenting symptom of pituitary adenoma.

    abstract：:A case, in which rhinorrhoea was caused by a pituitary adenoma, is presented. Leakage of CSF or metrizamide could be observed on CT. ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/0303-8467(84)90278-6

    authors： Bilo HJ,Ponssen H,van der Veen EA,Wolbers JG

    更新日期：1984-01-01 00:00:00

  • The interleukin-10 levels as a potential indicator of positive response to interferon beta treatment of multiple sclerosis patients.

    abstract：OBJECTIVES:Only a part of MS patients treated with interferon beta (IFN) respond positively to the applied treatment and to date no parameter predicting the response to treatment has been found. The aim of the study was to determine whether the levels of interleukin-10 and -12 (IL-10 and IL-12) might be the parameters ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.clineuro.2005.10.011

    authors： Bartosik-Psujek H,Stelmasiak Z

    更新日期：2006-10-01 00:00:00

  • Treatment allocation of ruptured anterior communicating artery aneurysms: The influence of aneurysm morphology.

    abstract：OBJECTIVES:Since publication of the ISAT study, the majority of neurovascular centers adhere to "coil first" policy for patients with subarachnoid hemorrhage (SAH). However, final allocation in favor of coiling or clipping is based on anatomic features of ruptured intracranial aneurysms with respect to clinical charact...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2019.105506

    authors： Darkwah Oppong M,Deuschl C,Pierscianek D,Rauschenbach L,Chihi M,Radbruch A,Dammann P,Wrede KH,Özkan N,Müller O,Forsting M,Sure U,Jabbarli R

    更新日期：2019-11-01 00:00:00

  • Peripheral facial nerve paralysis in children: the value of routine diagnostic work-up studies.

    abstract：:Acute facial nerve paralysis is a relatively common pediatric disorder. Idiopathic facial nerve palsy (Bell's palsy) has to be distinguished from other etiologies. Retrospective review of the results of routine diagnostic work-up studies of our patients, failed to reveal any clinically significant abnormalities and di...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/0303-8467(88)90007-8

    authors： Eshel G,Lahat E,Azizi E

    更新日期：1988-01-01 00:00:00

  • Acute ischemic stroke in the very elderly Chinese: risk factors, hospital management and one-year outcome.

    abstract：BACKGROUND:Little information is available on Asian patients over 80 years with stroke. We aimed to investigate characteristics of the very elderly ischemic stroke hospitalized patients in China. METHODS:We prospectively enrolled consecutive patients with acute ischemic stroke from March, 2002 to October, 2008 into th...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2011.01.005

    authors： Wang D,Hao Z,Tao W,Kong F,Zhang S,Wu B,Lin S,Liu M

    更新日期：2011-07-01 00:00:00

  • Molecular and clinical prognostic factors for favorable outcome following surgical resection of adult intramedullary spinal cord astrocytomas.

    abstract：OBJECTIVE:Intramedullary spinal cord astrocytomas are uncommon but important entities. Aggressive surgical resection is believed to be critical to prevent subsequent neurological deterioration; however, the prognostic significance of numerous patient and molecular variables remains unclear. We sought to investigate the...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2016.03.009

    authors： Xiao R,Abdullah KG,Miller JA,Lubelski D,Steinmetz MP,Shin JH,Krishnaney AA,Mroz TE,Benzel EC

    更新日期：2016-05-01 00:00:00

  • Facial motor evoked potentials in cerebellopontine angle surgery: technique, pitfalls and predictive value.

    abstract：OBJECTIVE:To obtain information on functional integrity of the facial nerve by transcranial electrical motor evoked potentials independent of nerve visualization and to improve prediction of postoperative function. PATIENTS AND METHODS:In a prospective clinical study, 68 patients with cerebello-pontine angle tumors an...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2011.06.011

    authors： Matthies C,Raslan F,Schweitzer T,Hagen R,Roosen K,Reiners K

    更新日期：2011-12-01 00:00:00

  • Thalamic deep brain stimulation for posttraumatic action tremor.

    abstract：:We report a case of thalamic deep brain stimulation (DBS) for treatment of posttraumatic tremor. An 18-year-old right-handed man developed a disabling and medically refractory action tremor in the right upper extremity 9 months after sustaining diffuse axonal injury in a motor vehicle collision. DBS of the left ventra...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2003.12.004

    authors： Umemura A,Samadani U,Jaggi JL,Hurtig HI,Baltuch GH

    更新日期：2004-09-01 00:00:00

  • Prevalence and determinants of depression in Mexican patients with Parkinson's disease.

    abstract：OBJECTIVE:To assess the prevalence and associated factors of depression in a Mexican Parkinson's disease (PD) population. BACKGROUND:Depressive symptoms are frequent in PD and have been recognized as a major determinant of quality of life. Only two previous studies have partially addressed depression in Mexican PD pat...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2012.03.035

    authors： Rodríguez-Violante M,Cervantes-Arriaga A,Berlanga-Flores C,Ruiz-Chow A

    更新日期：2012-12-01 00:00:00

  • Von Recklinghausen neurofibromatosis (VRNF) and pregnancy. A single case study.

    abstract：:A case of Von Recklinghausen neurofibromatosis (VRNF) with progression during two pregnancies and obstetrical complications is described to illustrate the effect of pregnancy on VRNF and vice versa. The interaction between VRNF and pregnancy is discussed. The obstetrical complications and progression of VRNF lesions d...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/s0303-8467(87)80052-5

    authors： Boiten J,Jansen EN,de Graaff R

    更新日期：1987-01-01 00:00:00

  • Chronic opioid use is associated with increased postoperative urinary retention, length of stay and non-routine discharge following lumbar fusion surgery.

    abstract：BACKGROUND:The incidence of chronic opioid use (COU) is increasing with health related complications impacting both patients and healthcare services. OBJECTIVE:The aim of this study was to identify the impact of COU on postoperative urinary retention (PUR) in patients following lumbar fusion surgery as well as its imp...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2020.106161

    authors： Doherty RJ,Wahood W,Yolcu YU,Zreik J,Goyal A,Gazelka HM,Habermann EB,Sebastian A,Bydon M

    更新日期：2020-10-01 00:00:00

  • Primary decompressive craniectomy for poor-grade middle cerebral artery aneurysms with associated intracerebral hemorrhage.

    abstract：OBJECTIVE:Aggressive surgery seems mandatory for poor-grade middle cerebral artery (MCA) aneurysm with associated intracerebral hemorrhage (ICH). However, primary decompressive craniectomy (DC) is controversial. We performed a case control study to define the role of primary DC. MATERIALS AND METHODS:We analyzed data ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.clineuro.2015.03.009

    authors： Zhao B,Zhao Y,Tan X,Cao Y,Wu J,Zhong M,Wang S

    更新日期：2015-06-01 00:00:00

  • Axonal damage in multiple sclerosis: a complex issue in a complex disease.

    abstract：:Multiple sclerosis is no longer considered to simply be an autoimmune demyelinating disease. Axonal destruction is another central pathological feature and a contributor to the accumulating disability of disease progression. The mechanism underlying axonal pathology has not been fully clarified but does not appear to ...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章,评审

    doi：10.1016/j.clineuro.2004.02.017

    authors： Grigoriadis N,Ben-Hur T,Karussis D,Milonas I

    更新日期：2004-06-01 00:00:00

  • Hypo-fractionated stereotactic radiotherapy of five fractions with linear accelerator for vestibular schwannomas: A systematic review and meta-analysis.

    abstract：:Vestibular schwannomas (VS) are benign tumors stemming from the eighth cranial nerve. Treatment options for VS include conservative management, microsurgery, stereotactic radiosurgery, and fractionated radiotherapy. Though microsurgery has been the standard of care for larger lesions, hypo-fractionated stereotactic ra...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.clineuro.2018.01.005

    authors： Nguyen T,Duong C,Sheppard JP,Lee SJ,Kishan AU,Lee P,Tenn S,Chin R,Kaprealian TB,Yang I

    更新日期：2018-03-01 00:00:00

  • New cerebral microbleeds in ischemic stroke patients on warfarin treatment: two-year follow-up.

    abstract：OBJECTIVE:Cerebral microbleeds (CMBs) are known to be indicative of bleeding-prone microangiopathy. Little is known about the significance of CMBs in anticoagulated patients. We determined the frequency of new CMBs in ischemic stroke patients who had been receiving warfarin treatment for 2 years. METHODS:A total of 20...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2013.03.004

    authors： Orken DN,Uysal E,Timer E,Kuloglu-Pazarcı N,Mumcu S,Forta H

    更新日期：2013-09-01 00:00:00

  • One-stage coiling versus clipping of multiple intracranial aneurysms in elderly patients.

    abstract：OBJECTIVES:Although multiple intracranial aneurysms (MIAs) are frequent and disastrous, determining treatment strategy for them is often complicated, especially in elderly patients (≥60 years old). We evaluated the safety and effectiveness of one-stage coiling versus surgical clipping for MIAs in elderly patients. MET...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2020.106415

    authors： Xie Q,Gu Y,Song Y,Leng B,Zheng Y,Xu F

    更新日期：2020-12-05 00:00:00

  • Infrasellar craniopharyngioma.

    abstract：OBJECT:Infrasellar craniopharyngioma (IC) is a rare tumor. This study aimed to investigate the clinical manifestations, treatment methods, and prognosis of IC, which invades the cranial base, nasal sinuses, nasopharynx and clivus. METHODS:Eleven consecutive cases of IC who received treatment in People's Liberation Arm...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2011.09.010

    authors： Yu X,Liu R,Wang Y,Wang H,Zhao H,Wu Z

    更新日期：2012-02-01 00:00:00

  • Spinal cord stimulation in the treatment of complex regional pain syndrome type 1: Is trial truly required?

    abstract：OBJECTIVE:Spinal cord stimulation has been proven highly effective in the treatment of Complex Regional Pain Syndrome (CRPS). The definitive implantation of a neurostimulator is usually preceded by a therapeutic test (trial), which has the purpose of identifying whether the patient would respond positively to neuromodu...

    journal_title：Clinical neurology and neurosurgery

    pub_type： 杂志文章

    doi：10.1016/j.clineuro.2018.06.014

    authors： Risson EG,Serpa AP,Berger JJ,Koerbel RFH,Koerbel A

    更新日期：2018-08-01 00:00:00