Abstract：
:Multiple sclerosis (MS) has several clinically different forms. Whereas the illness progresses slowly in most of the patients, 10% have an aggressively progressive course with fatal outcome without signs of remyelination capability. The process of remyelination depends on numerous interactive factors, including the presence of various growth factors, the most important of which in the adult is insulin growth factor-I (IGF-I). On the other hand, the most powerful postnatal regulator of IGF-I is growth hormone (GH), which also acts as a neuroprotective and an antiapoptotic agent, and has direct influence on myelination. Levels of these growth factors have never been examined in the cerebrospinal fluid (CSF) of patients with MS. The levels of IGF-I and GH were measured in serum and CSF of 46 MS patients and compared with those of 49 patients with no evidence of demyelinating disease. The only positive finding was a deficiency of GH in the CSF of MS patients. The possible implications of those findings in the etiopathogenesis of MS will be discussed.
journal_name
Clin Neurol Neurosurgjournal_title
Clinical neurology and neurosurgeryauthors
Poljakovic Z,Zurak N,Brinar V,Korsic M,Basic S,Hajnsek Sdoi
10.1016/j.clineuro.2005.11.014keywords:
subject
Has Abstractpub_date
2006-03-01 00:00:00pages
255-8issue
3eissn
0303-8467issn
1872-6968pii
S0303-8467(05)00213-1journal_volume
108pub_type
杂志文章abstract：:Recent studies have reported that microRNA-155 (miR-155) is linked to the clinical outcomes of many tumors. However, its role in prognosis of gliomas remains unclear. This meta-analysis aims to evaluate the prognostic value of miR-155 in the survival of patients with gliomas. Hazard ratios (HRs) with 95% confidence in...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.clineuro.2018.12.005
更新日期：2019-01-01 00:00:00
abstract：:We report a 38-year-old male patient who developed a Miller Fisher syndrome following a respiratory tract disorder associated with a serologically proven Mycoplasma pneumoniae infection. Although several neurologic manifestations have been reported after Mycoplasma pneumonia infection, Miller Fisher syndrome has not b...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/0303-8467(94)90038-8
更新日期：1994-02-01 00:00:00
abstract：:Two siblings suffering from acro-osteolysis, a rare disorder, are discussed. Although three distinct types of acro-osteolysis, namely familial, idiopathic, and due to vinyl-chloride, are clearly defined, these patients did not fit into any category. They had intact nails, preserved tactile and sensory system, plantar ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/0303-8467(80)90059-1
更新日期：1980-01-01 00:00:00
abstract：:A 7-year-old girl presented with focal seizures without symptoms of raised intracranial tension. Routine histological, immunocytochemical and ultrastructural methods revealed a desmoplastic low grade cerebral astrocytoma. Follow up for 2 years after biopsy did not show recruitment of neurological symptoms or signs. Bi...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/0303-8467(94)00051-7
更新日期：1995-02-01 00:00:00
abstract：:Meningiomas are the most common benign intracranial tumors in adults arising from the dura matter. The etiology of meningiomas is mostly unknown, although several risk factors have been described, such as ionizing radiation, head injury, hormones and genetic factors. According to WHO they are classified into 3 grades,...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2010.12.007
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:The ultrasonography findings in the superficial temporal artery (STA) in Moyamoya disease patients treated with indirect bypass remain unclear. We evaluated the time-related changes in ultrasonography findings of the STA main trunk and branches in patients with Moyamoya disease who underwent encephalo-duro-ar...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2017.06.013
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:This study was performed to evaluate the association between red blood cell distribution width (RDW) and 3-month mortality in patients with aneurysmal subarachnoid hemorrhage. PATIENTS AND METHODS:This observational study was performed from March 2007 to May 2017 in an emergency department. The baseline cha...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2018.06.044
更新日期：2018-09-01 00:00:00
abstract：:The clinicopathological features of a lipomatous meningioma of the falx cerebri with an unusual histological pattern are presented. ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(00)00094-9
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:We performed a retrospective study to identify factors associated with preoperative and late postoperative seizures in primary supratentorial meningiomas. PATIENTS AND METHODS:Between July 2003 and December 2014, we extracted 303 consecutive patients who underwent primary resection for supratentorial meningi...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2019.03.007
更新日期：2019-05-01 00:00:00
abstract：:Non-pituitary lesions account for a minority of sellar region abnormalities. We report the unusual occurrence of non-pituitary sellar/suprasellar lesions in a mother and her two daughters. Each of these cases was diagnosed and managed differently, illustrating the relative importance of radiographic imaging, tumor mar...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2007.09.021
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to translate new evidence about management of spinal metastases in a practical and reliable score for surgeons, radiation oncologists and oncologists, able to establish the need for surgery regardless the available technology and settings. PATIENTS AND METHODS:Three main items were ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.105896
更新日期：2020-08-01 00:00:00
abstract：:Essential Tremor (ET) is characterized by a 4-12-Hz postural and kinetic tremor, most commonly affecting the upper limbs. Deep brain stimulation (DBS) of the thalamus (Vim) has been found to be highly effective in severe/refractory forms of ET. Intra-operative assessment of tremor is performed using clinical methods b...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2008.10.017
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:The authors investigated the feasibility of a transforaminal endoscopic decompression and un-instrumented lumbar interbody fusion procedures with cancellous bone allograft in patients painful with end-stage degenerative vacuum disc disease. PATIENTS & METHODS:Twenty-nine patients who underwent endoscopic tra...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.106002
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:Chronic subdural hematoma (CSDH) is a condition that is frequently seen in the neurological and neurosurgical practice. Surgical treatment is overall preferred; however, conservative treatment is also an option. Both surgical and conservative treatment of CSDH vary across neurosurgeons. The aim of the present...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.105899
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Cranial nerve deficits during CEA are a known complication. The purpose of this study is to evaluate if significant changes in somatosensory evoked potentials and electroencephalography increase cranial nerve deficits during CEA. PROCEDURES:This is an observational retrospective case-control study analyzed ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2014.12.017
更新日期：2015-03-01 00:00:00
abstract：:It is rare for a dermoid cyst to develop intratumoral hemorrhage. A 61-year-old woman had a sudden-onset left hemiparesis and slow response to verbal requests for one week when unenhanced computed tomography scanning revealed a mixed iso- and hypo-dense heterogeneous lesion in the right fronto-temporal area. T1-weight...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2004.11.003
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:Transradial access has recently been gaining more popularity in various neurointerventional procedures. To this day, a systematic review and meta-analysis investigating the outcomes of transradial access for mechanical thrombectomy in acute stroke have not been performed. METHODS:PubMed, Embase, and Scopus d...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.106235
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVES:Electrical cortical stimulation mapping (ECSM) is the current gold standard functional mapping technique; however, it is burdened by several limitations. Our objective in this study is to show that extended functional mapping modalities can (1) allow neurosurgeons to map and preserve eloquent regions that ar...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2017.10.008
更新日期：2017-12-01 00:00:00
abstract：:Tardive dyskinesia (TD) is a hyperkinetic movement disorder induced by dopamine receptor blocking drugs (DRBDs). TD typically presents with stereotypy or dystonia, but may also cause akathisia, myoclonus, or tremor. However, no detailed reports of gait abnormalities have been documented. We report three patients expos...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2007.09.013
更新日期：2008-02-01 00:00:00
abstract：:Gangliocytoma of the sellar region are extremely rare and often coexist with pituitary adenoma. Aim of this review is to collect all the cases reported in literature and to summarize the most recent literature evidences on the subject. A systematic review was performed through PubMed searching for articles describing ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.clineuro.2016.08.002
更新日期：2016-10-01 00:00:00
abstract：:Recently, social media showed musicians performing pieces during awake surgery for brain diseases, such as tumors or dystonia. They tend to emphasize the use of intraoperative performance. Our aim is to review the literature on intraoperative performance in awake surgery for musicians, in order to understand if it is ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.clineuro.2020.105911
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To review the changes in the management of aneurysmal subarachnoid haemorrhage (SAH) in a single neurosurgical unit in the UK, following the publication of the international subarachnoid aneurysm trial (ISAT). METHODS:The presentation, investigations, treatments and outcome data of all patients admitted with...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2005.11.001
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE:Delayed facial palsy (DFP) has often been described during the recovery stage of Fisher syndrome (FS), but the implications of DFP in FS pathophysiology have not been reported previously. The aim of this study was to identify the incidence and clinical course of DFP in FS, and to determine its clinical/pathop...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2015.04.025
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:Decompression surgery is the standard treatment for lumbar spinal stenosis (LSS); however, despite the good clinical outcomes reported for this procedure, a relatively high dissatisfaction rate has been reported. We hypothesized that the previously used outcome measures do not accurately reflect patient satis...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.105710
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVES:Spinal intramedullary tuberculosis is a rare disease. This study aims to acquaint readers with its clinicoradiological features and emphasizes the importance of early treatment in intramedullary spinal tuberculosis. MATERIALS AND METHODS:Retrospective analysis was conducted from 1985 to 2006 over a period o...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2008.09.029
更新日期：2009-02-01 00:00:00
abstract：:Bilateral Symmetrical Calcifications (B.S.C.) in cerebro represent calcium deposits usually found in the basal ganglia and/or dentate nucleus. They can be the result of diverse disorders, but can also present themselves without any underlying disease. Most often they are asymptomatic, but if the calcifications are ext...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(88)80036-2
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:Mechanical thrombectomy (MT) following intravenous administration of recombinant tissue-type plasminogen activator (IV-rt-PA) is considered an effective treatment for the occlusion of the internal carotid artery or the M1 segment of the middle cerebral artery. However, its efficacy in treating basilar artery ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.105796
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:Understanding the microanatomy of the proximal middle cerebral artery (M1) and its early branches is very important for aneurysm surgery in this region. However, few articles provide detailed descriptions of such aneurysms. We report the angiographic characteristics of a series of M1 aneurysms and our experie...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2008.02.014
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVES:Mild cognitive impairment (MCI) may represent a transition to early Alzheimer's disease (AD). The retinal nerve fiber layer (RNFL) is composed of axons originating in retinal ganglion cells that eventually form the optic nerves. Previous studies have shown that degenerative changes occur in optic nerve fiber...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2011.02.014
更新日期：2011-09-01 00:00:00
abstract：:The authors describe a case of calcified, organized hematoma in the cerebellopontine angle which developed 20 years after subtotal removal of an acoustic neurinoma, presenting as a recurrence of acoustic neurinoma on computed tomography. It points out the difficulty in differentiating a recurrent tumor from an organiz...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(88)80013-1
更新日期：1988-01-01 00:00:00
