Patterns of seminoma tissue markers and deletions.

abstract：:Estrogen signaling plays an important role in breast carcinogenesis. An increased understanding of estrogen gene targets and their effects will allow for more directed and effective therapies for individuals with breast cancer, particularly those with estrogen receptor positive tumors resistant to tamoxifen therapy. H...

journal_title：International journal of cancer

authors： Tuttle R,Miller KR,Maiorano JN,Termuhlen PM,Gao Y,Berberich SJ

更新日期：2012-05-15 00:00:00

abstract：:We studied the in vivo growth-inhibitory effect of the new S-adenosylmethionine decarboxylase inhibitor 4-amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A). L1210-bearing DBA-2 mice were treated with increasing CGP 48664A doses from 1 day after i.p. L1210 cell inoculation. Treatment was continued for 4 days, after w...

journal_title：International journal of cancer

authors： Dorhout B,Te Velde RJ,Ferwerda H,Kingma AW,De Hoog E,Muskiet FA

更新日期：1995-04-10 00:00:00

abstract：:The sensitivity of human tissues and tumors to infection with type C adenoviruses correlates with the expression of the human coxsackie B- and adenovirus receptor, hCAR. HCAR is heterogeneously expressed in various tissues and types of human cancer cells, which has implications for the use of adenoviruses as vectors i...

journal_title：International journal of cancer

authors： Fuxe J,Liu L,Malin S,Philipson L,Collins VP,Pettersson RF

更新日期：2003-03-01 00:00:00

abstract：:PDT has been reported to induce cancer cell expression of cytokines, such as IL-6 and TNF-alpha, but it has been unclear whether cytokine expression by cancer cells is directly related to the antitumor effect of PDT. We treated Lewis lung carcinoma (LLC) cells with a new photosensitizer, mono-L-aspartyl chlorin e6 (NP...

journal_title：International journal of cancer

authors： Usuda J,Okunaka T,Furukawa K,Tsuchida T,Kuroiwa Y,Ohe Y,Saijo N,Nishio K,Konaka C,Kato H

更新日期：2001-08-15 00:00:00

abstract：:Studies have shown an increased risk of malignancies in women with endometriosis. Little is known about the impact of endometriosis on cancer survival. We investigated whether the survival after a diagnosis of a malignancy differs in women with a previously diagnosed endometriosis compared to other women. Women with a...

journal_title：International journal of cancer

authors： Melin A,Lundholm C,Malki N,Swahn ML,Sparen P,Bergqvist A

更新日期：2011-08-15 00:00:00

abstract：:Although reproductive factors have been shown to be related to the composition of bile and functioning of the biliary system, their relationship with biliary tract cancer has not been studied in detail. Between 1984 and 1987 we conducted a case-control study of 75 women with cancer of the biliary tract and 252 control...

journal_title：International journal of cancer

authors： Moerman CJ,Berns MP,Bueno de Mesquita HB,Runia S

更新日期：1994-04-15 00:00:00

abstract：:Previous studies have shown that the in vitro-selected adriamycin-resistant human small-cell lung-carcinoma cell line GLC4-ADR150 displays multidrug resistance as the result of 3-fold decreased DNA-topoisomerase II (topo II) activity and a 6-fold reduction in adriamycin accumulation. Not the MDR1 gene, but the MRP gen...

journal_title：International journal of cancer

authors： Versantvoort CH,Withoff S,Broxterman HJ,Kuiper CM,Scheper RJ,Mulder NH,de Vries EG

更新日期：1995-05-04 00:00:00

abstract：:We have examined the effects of the synthetic matrix metalloproteinase inhibitor, batimastat (BB-94) and the angiotensin-converting enzyme inhibitor, captopril, on metalloproteinase activity of murine Lewis-lung-carcinoma cells (3LL) in vitro, and on local growth and lung metastasis of the same tumor implanted intramu...

journal_title：International journal of cancer

authors： Prontera C,Mariani B,Rossi C,Poggi A,Rotilio D

更新日期：1999-05-31 00:00:00

abstract：:Cholangiocarcinoma is the second most common primary hepatic cancer, with a rising incidence worldwide. Owing to late diagnosis and limited treatment options, the prognosis for cholangiocarcinoma remains dismal, compelling a search for new treatments. As aspirin exhibits a well-supported chemopreventive effect on comm...

journal_title：International journal of cancer

authors： Shen X,Shen X

更新日期：2021-03-15 00:00:00

abstract：:A "divergent pathway" model for the development of cutaneous melanoma has been proposed. The model hypothesizes that melanomas occurring in people with a low tendency to develop nevi will, on average, arise more commonly on habitually sun-exposed body sites such as the head and neck. In contrast, people with an inhere...

journal_title：International journal of cancer

authors： Olsen CM,Zens MS,Stukel TA,Sacerdote C,Chang YM,Armstrong BK,Bataille V,Berwick M,Elwood JM,Holly EA,Kirkpatrick C,Mack T,Bishop JN,Østerlind A,Swerdlow AJ,Zanetti R,Green AC,Karagas MR,Whiteman DC

更新日期：2009-02-15 00:00:00

abstract：:While chrysotile has been commonly used by Chinese textile industry for many years, investigations on the association of chrysotile exposure with risk of mesothelioma in China are scarce. We conducted a case-control study in a county located at Southeastern China, including 46 cases and 230 individually matched contro...

journal_title：International journal of cancer

authors： Jiang Z,Chen T,Chen J,Ying S,Gao Z,He X,Miao C,Yu M,Feng L,Xia H,Wu W,Chen R,Morinaga K,Lou J,Zhang X

更新日期：2018-02-01 00:00:00

abstract：:Using antisera for two specific basement membrane (b.m.) antigens such as laminin and collagen type-IV, together with electron microscopy, we have shown that fully antigenic b.m. and morphologically typical basal lamina (b.l.) are associated with normal and transformed cells of the melanocyte lineage in different ways...

journal_title：International journal of cancer

authors： Natali PG,Nicotra MR,Bellocci M,Cavaliere R,Bigotti A

更新日期：1985-04-15 00:00:00

abstract：:Human papillomavirus (HPV) has been identified as a causative agent of cervical cancer and oropharyngeal cancer (OPC). Intriguingly, estrogen and HPV were shown to play synergistic roles in cervical carcinogenesis. We recently demonstrated that the apolipoprotein B mRNA-editing catalytic polypeptide 3 (APOBEC3, A3) fa...

journal_title：International journal of cancer

authors： Kano M,Kondo S,Wakisaka N,Wakae K,Aga M,Moriyama-Kita M,Ishikawa K,Ueno T,Nakanishi Y,Hatano M,Endo K,Sugimoto H,Kitamura K,Muramatsu M,Yoshizaki T

更新日期：2019-09-15 00:00:00

abstract：:In advanced cancer patients, the oxidative stress could take place either at the onset of disease or as a function of disease progression. To test this hypothesis, the following parameters were investigated: the erythrocyte activity of the enzymes superoxide dismutase (SOD) and glutathione peroxidase (GPx), the serum ...

journal_title：International journal of cancer

authors： Mantovani G,Macciò A,Madeddu C,Mura L,Gramignano G,Lusso MR,Mulas C,Mudu MC,Murgia V,Camboni P,Massa E,Ferreli L,Contu P,Rinaldi A,Sanjust E,Atzei D,Elsener B

更新日期：2002-03-01 00:00:00

abstract：:The expression of the recently described rap genes, closely related in the effector region to the ras proto-oncogenes, was examined by Northern blot analysis in 41 primary human tumors. The structural and in vitro biological properties of the rap gene products suggest their possible antagonistic action in the same eff...

journal_title：International journal of cancer

authors： Culine S,Olofsson B,Gosselin S,Honore N,Tavitian A

更新日期：1989-12-15 00:00:00

abstract：:A glucuronide doxorubicin prodrug N-[4-doxorubicin-N-carbonyl (oxymethyl) phenyl] O-beta-glucuronyl carbamate (DOX-GA3) has been developed to improve the antitumor effects of doxorubicin (DOX). The prodrug was originally designed to be activated into drug by human beta-glucuronidase (GUS) released from tumor cells in ...

journal_title：International journal of cancer

authors： Houba PH,Boven E,van der Meulen-Muileman IH,Leenders RG,Scheeren JW,Pinedo HM,Haisma HJ

更新日期：2001-02-15 00:00:00

abstract：:The human bowel contains a large and dynamic bacterial population that is not only essential for intestinal health, but also critical for the development of diseases such as cancer. In this respect, the Gram-positive bacterium Streptococcus bovis has been associated with colon cancer for many years. To investigate the...

journal_title：International journal of cancer

authors： Tjalsma H,Schöller-Guinard M,Lasonder E,Ruers TJ,Willems HL,Swinkels DW

更新日期：2006-11-01 00:00:00

abstract：:This study investigates the role of tumor nitric oxide (NO) and vascular regulation in tumor ulceration following high-dose tumor necrosis factor-alpha (TNF) treatment. Using TNF-responsive (MethA) and nonresponsive (LL2) mouse tumors, tumor NO concentration was measured with an electrochemical sensor and tumor blood ...

journal_title：International journal of cancer

authors： Menon C,Bauer TW,Kelley ST,Raz DJ,Bleier JI,Patel K,Steele K,Prabakaran I,Shifrin A,Buerk DG,Sehgal CM,Fraker DL

更新日期：2008-07-15 00:00:00

abstract：:Spreading is a critical process involved in motility and growth of tumor cells during the metastatic cascade. Focal adhesion kinase, src-proteins and PKC have been reported to participate in the regulation of cytoskeleton organization in both normal and transformed cells during spreading. The role of other signaling e...

journal_title：International journal of cancer

authors： Aguirre Ghiso JA,Farías EF,Alonso DF,Arregui C,Bal de Kier Joffé E

更新日期：1997-05-29 00:00:00

abstract：:Although the existence of a humoral response against tumor-associated antigens is well appreciated, a systematic analysis of its possible induction by the tumor remains missing. We compared the specific IgG response of Stage IV melanoma patients during vaccination. Patients had been treated within 2 clinical trials wi...

journal_title：International journal of cancer

authors： Ehlken H,Schadendorf D,Eichmüller S

更新日期：2004-01-10 00:00:00

abstract：:Accurate prognostic parameters in prostate biopsies are needed to better counsel individual patients with prostate cancer. We evaluated the prognostic impact of morphologic and immunohistochemical parameters in preoperative prostate cancer biopsies. A consecutive series of prostate biopsies of 279 men (72% with clinic...

journal_title：International journal of cancer

authors： Zellweger T,Günther S,Zlobec I,Savic S,Sauter G,Moch H,Mattarelli G,Eichenberger T,Curschellas E,Rüfenacht H,Bachmann A,Gasser TC,Mihatsch MJ,Bubendorf L

更新日期：2009-05-01 00:00:00

abstract：:It has been suggested that smoking is associated with estrogen-negative breast cancer but not with estrogen-positive breast cancer. A population-based case-control study was conducted in Geneva, Switzerland, to determine the relation of passive and active smoking to breast cancer when the referent unexposed category c...

journal_title：International journal of cancer

authors： Morabia A,Bernstein M,Ruiz J,Héritier S,Diebold Berger S,Borisch B

更新日期：1998-01-30 00:00:00

abstract：:A new cell line from a sporadic Wilms' tumor was established and extensively characterized. In nude mice, the tumor cells rapidly formed tumors which, in histological characteristics and extracellular-matrix (ECM) composition resembled sarcomatoid Wilms' tumor. The tumor cells produced B chains of laminin, but no A ch...

journal_title：International journal of cancer

authors： Talts JF,Aufderheide E,Sorokin L,Ocklind G,Mattsson R,Ekblom P

更新日期：1993-07-09 00:00:00

abstract：:We recently reported the identification of a human SART3 gene that encodes a tumor-rejection antigen recognized by cytotoxic T lymphocytes (CTLs). The squamous-cell carcinoma antigen recognized by T cells-3 (SART3) is an RNA-binding protein expressed in the nucleus of the majority of proliferating cells, including nor...

journal_title：International journal of cancer

authors： Harada K,Yamada A,Yang D,Itoh K,Shichijo S

更新日期：2001-09-01 00:00:00

abstract：:Previous studies have shown that macrophage cell lines retained the ability to phagocytize, to secrete lysosomal enzymes, and to function as effector cells in antibody-dependent cellular cytoxicity. In this paper, the cytolytic activity of murine macrophage cell lines against tumor target cells was assessed using an 1...

journal_title：International journal of cancer

authors： Taniyama T,Holden HT

更新日期：1980-07-15 00:00:00

abstract：:This article has been retracted at the request of: Editor-in-Chief and Co-author 'Restoring sensitivity to oxaliplatin by a novel approach in gemcitabine-resistant pancreatic cancer cells in vitro and in vivo' by Banerjee, S., Kong, D., Azmi, A. S., Wang, Z., Ahmad, A., Sethi, S. and Sarkar, F. H. The above article, p...

journal_title：International journal of cancer

authors：

更新日期：2016-11-01 00:00:00

abstract：:Dietary patterns reflect combinations of dietary exposures, and here we examine these in relation to prostate cancer risk. In a case-control study, 80 incident primary prostate cancer cases and 334 urology clinic controls were enrolled from 1997 through 1999 in Kingston, Ontario, Canada. Food-frequency questionnaires ...

journal_title：International journal of cancer

authors： Walker M,Aronson KJ,King W,Wilson JW,Fan W,Heaton JP,MacNeily A,Nickel JC,Morales A

更新日期：2005-09-10 00:00:00

abstract：:The survival experience of 284 patients with cancer of the cervix uteri registered by the population-based Zimbabwe National Cancer Registry in 1995-1997 is described. The vital status of these subjects was established by linkage with death registration and by retrieval of patient files from medical records department...

journal_title：International journal of cancer

authors： Chokunonga E,Ramanakumar AV,Nyakabau AM,Borok MZ,Chirenje ZM,Sankila R,Parkin DM

更新日期：2004-03-20 00:00:00

abstract：:In childhood acute lymphoblastic leukaemia there are large interpatient variations in levels of the apoptosis-regulating proteins Bax and Bcl-2, but the molecular basis for this variation is unknown. Point-mutations in bax have been reported in cell lines derived from haematological malignancies. Frameshift mutations,...

journal_title：International journal of cancer

authors： Salomons GS,Buitenhuis CK,Martínez Muñoz C,Verwijs-Jassen M,Behrendt H,Zsiros J,Smets LA

更新日期：1998-06-19 00:00:00

abstract：:Trilaciclib is an intravenous CDK4/6 inhibitor administered prior to chemotherapy to preserve haematopoietic stem and progenitor cells and immune system function from chemotherapy-induced damage (myelopreservation). The effects of administering trilaciclib prior to carboplatin, etoposide and atezolizumab (E/P/A) were ...

journal_title：International journal of cancer

authors： Daniel D,Kuchava V,Bondarenko I,Ivashchuk O,Reddy S,Jaal J,Kudaba I,Hart L,Matitashvili A,Pritchett Y,Morris SR,Sorrentino JA,Antal JM,Goldschmidt J

更新日期：2020-12-21 00:00:00