Localized thymic amyloidosis presenting with myasthenia gravis: case report.

Abstract:

:A mediastinal mass was incidentally found on chest radiography in a 46-yr-old woman who had had myasthenia gravis (MG) for 2 months. Computed tomography revealed a 4-cm in size, well-defined, and lobulating mass with nodular calcification that was located in the thymus. Microscopically, the mass consisted of diffuse amorphous eosinophilic materials. These deposits exhibited apple-green birefringence under polarized light microscopy after Congo red staining. Immunohistochemical analysis revealed that they were positive for both kappa and lambda light chains and negative for amyloid A. A diagnosis of localized primary thymic amyloidosis was finally made. After thymectomy, the symptoms of MG were controlled with reduced corticosteroid requirements. Localized thymic amyloidosis associated with MG has not been reported to date.

journal_name

J Korean Med Sci

authors

Son SM,Lee YM,Kim SW,Lee OJ

doi

10.3346/jkms.2014.29.1.145

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

145-8

issue

1

eissn

1011-8934

issn

1598-6357

journal_volume

29

pub_type

杂志文章
  • Three-year outcomes of the innovative replacement of incontinence surgery procedure for treatment of female stress urinary incontinence: comparison with tension-free vaginal tape procedure.

    abstract::Innovative replacement of incontinence surgery (IRIS) is a polypropylene tape that is placed beneath the midurethra to restore urinary continence. We evaluated the long-term efficacy and safety of the IRIS procedure and compared it with tension-free vaginal tape (TVT) for the treatment of female stress urinary inconti...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2007.22.3.497

    authors: Yoon CJ,Jung HC

    更新日期:2007-06-01 00:00:00

  • Cross-sectional illustration on major types of conjoined twins.

    abstract::Conjoined twins show varying degree of conjoining in either facing or side-by-side fashion. Cephalothoracopagus janiceps is a prototype of facing anomaly in which the two bodies demonstrated a cross symmetry to the midline, that is axial symmetry. Interfacial and intersternal lines crossed at a right angle and no abno...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1988.3.1.19

    authors: Seo JW,Lee YS,Chi JG

    更新日期:1988-03-01 00:00:00

  • Genetic correlation of community-associated methicillin-resistant Staphylococcus aureus strains from carriers and from patients with clinical infection in one region of Korea.

    abstract::Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is an increasingly common worldwide and colonizing S. aureus strains may serve as the causative pathogen for overt clinical infections. This study was performed to determine whether the pathogenic CA-MRSA isolate in clinical infections was geneti...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2010.25.2.197

    authors: Bae IG,Kim JS,Kim S,Heo ST,Chang C,Lee EY

    更新日期:2010-02-01 00:00:00

  • Tempol attenuates renal fibrosis in mice with unilateral ureteral obstruction: the role of PI3K-Akt-FoxO3a signaling.

    abstract::This study investigated whether tempol, an anti-oxidant, protects against renal injury by modulating phosphatidylinositol 3-kinase (PI3K)-Akt-Forkhead homeobox O (FoxO) signaling. Mice received unilateral ureteral obstruction (UUO) surgery with or without administration of tempol. We evaluated renal damage, oxidative ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2014.29.2.230

    authors: Yoon HE,Kim SJ,Kim SJ,Chung S,Shin SJ

    更新日期:2014-02-01 00:00:00

  • Percutaneous papillary large balloon dilation during percutaneous cholangioscopic lithotripsy for the treatment of large bile-duct stones: a feasibility study.

    abstract::When access to a major duodenal papilla or endoscopic retrograde cholangiopancreatography has failed, percutaneous transhepatic cholangioscopic lithotripsy (PTCS-L) may be useful for removing common bile duct (CBD) stones. However, the feasibility and usefulness of percutaneous transhepatic papillary large-balloon dil...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2015.30.3.278

    authors: Han JY,Jeong S,Lee DH

    更新日期:2015-03-01 00:00:00

  • Cowden's disease--a report on the first case in Korea and literature review.

    abstract::Cowden's disease, or multiple hamartoma syndrome, is an uncommon condition with characteristic mucocutaneous lesions associated with abnormalities of the breast, thyroid, and gastrointestinal tract. We describe a 32-year-old man with oral mucosal papillomatosis and plantar hyperkeratosis as a definite case of Cowden's...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.1997.12.6.570

    authors: Lee HR,Moon YS,Yeom CH,Kim KW,Chun JY,Kim HK,Choi HS,Kim DK,Chung TS

    更新日期:1997-12-01 00:00:00

  • Corporeal blood gas changes according to duration of drug-induced prolonged erection.

    abstract::The corporeal blood gas changes in accordance with the duration of the prolonged erection which developed after intracorporeal pharmacotherapy with papaverine and phentolamine were investigated in 62 impotence patients. The picture of the corporeal blood taken from 15 psychogenic impotence patients (a control group) a...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1993.8.3.202

    authors: Kim SC,Seo KK,Oh CH

    更新日期:1993-06-01 00:00:00

  • A Novel Fundus Image Reading Tool for Efficient Generation of a Multi-dimensional Categorical Image Database for Machine Learning Algorithm Training.

    abstract:Background:We described a novel multi-step retinal fundus image reading system for providing high-quality large data for machine learning algorithms, and assessed the grader variability in the large-scale dataset generated with this system. Methods:A 5-step retinal fundus image reading tool was developed that rates im...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e239

    authors: Park SJ,Shin JY,Kim S,Son J,Jung KH,Park KH

    更新日期:2018-08-08 00:00:00

  • Recently occurring adult tetanus in Korea: emphasis on immunization and awareness of tetanus.

    abstract::Since a nationwide childhood vaccination with tetanus toxoid, tetanus has become a rare disease in Korea. However, we recently experienced 17 cases of adult tetanus in a university hospital during a 21-month period. Seventy percent of the patients were female, and the mean age was 63 yr (range, 29-87). The majority (8...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.1.11

    authors: Shin DH,Yu HS,Park JH,Shin JH,Kim SJ

    更新日期:2003-02-01 00:00:00

  • Complete Recovery of Oxysterol 7α-Hydroxylase Deficiency by Living Donor Transplantation in a 4-Month-Old Infant: the First Korean Case Report and Literature Review.

    abstract::Oxysterol 7α-hydroxylase deficiency is a very rare liver disease categorized as inborn errors of bile acid synthesis, caused by CYP7B1 mutations. As it may cause rapid progression to end-stage liver disease even in early infancy, a high index of suspicion is required to prevent fatal outcomes. We describe the case of ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e324

    authors: Hong J,Oh SH,Yoo HW,Nittono H,Kimura A,Kim KM

    更新日期:2018-11-22 00:00:00

  • Urine Methyl Hippuric Acid Levels in Acute Pesticide Poisoning: Estimation of Ingested Xylene Volume and Association with Clinical Outcome Parameters.

    abstract::To determine the relationship between the oral ingestion volume of xylene and methyl hippuric acid (MHA) in urine, we measured MHA in 11 patients whose ingested xylene volume was identified. The best-fit equation between urine MHA and ingested amount of xylene was as follows: y (ingested amount of xylene, mL/kg) = -0....

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2017.32.12.2051

    authors: Choi CY,Cho N,Park SY,Park S,Gil HW,Hong SY

    更新日期:2017-12-01 00:00:00

  • Identification of Downstream Genes of the mTOR Pathway that Predict Recurrence and Progression in Non-Muscle Invasive High-Grade Urothelial Carcinoma of the Bladder.

    abstract::Microarray analysis was used to investigate the lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes to overcome cross-talk at non-muscle invasive high-grade (HG)-urothelial carcinoma (UC) of the bladder, gene expression patterns, gene ontology, and gene clustering by triple (p70S6K, S6K, a...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2017.32.8.1327

    authors: Jin S,Chang IH,Kim JW,Whang YM,Kim HJ,Hong SA,Lee TJ

    更新日期:2017-08-01 00:00:00

  • Atypical pathogens as etiologic agents in hospitalized patients with community-acquired pneumonia in Korea: a prospective multi-center study.

    abstract::Local epidemiologic data on the etiologies of patients hospitalized with community-acquired pneumonia (CAP) is needed to develop guidelines for clinical practice. This study was conducted prospectively to determine the proportion of atypical bacterial pathogens in adults patients hospitalized with CAP in Korea between...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,多中心研究

    doi:10.3346/jkms.2006.21.4.602

    authors: Sohn JW,Park SC,Choi YH,Woo HJ,Cho YK,Lee JS,Sim HS,Kim MJ

    更新日期:2006-08-01 00:00:00

  • Virus Isolation from the First Patient with SARS-CoV-2 in Korea.

    abstract::Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first l...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2020.35.e84

    authors: Park WB,Kwon NJ,Choi SJ,Kang CK,Choe PG,Kim JY,Yun J,Lee GW,Seong MW,Kim NJ,Seo JS,Oh MD

    更新日期:2020-02-24 00:00:00

  • Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.

    abstract::NAD(P)H oxidase plays an important role in hypertension and its complication in aldosterone-salt rat. We questioned whether NAD(P)H oxidase subunit expression and activity are modulated by aldosterone and whether this is associated with target-organ damage. Rats were infused with aldosterone (0.75 microg/hr/day) for 6...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2008.23.6.1039

    authors: Park YM,Lim BH,Touyz RM,Park JB

    更新日期:2008-12-01 00:00:00

  • A catastrophic-onset longitudinal myelitis accompanied by bilateral internuclear ophthalmoplegia in a patient with systemic lupus erythematosus.

    abstract::Transverse myelitis (TM) extending from midbrain to the entire spinal cord accompanied by internuclear ophthalmoplegia is extremely rare but cause serious central nervous system complications in patients with systemic lupus erythematosus. We report a case of a 28-yr-old woman with TM extending from the midbrain to the...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.6.1085

    authors: Rheu CW,Lee SI,Yoo WH

    更新日期:2005-12-01 00:00:00

  • Bone marrow pathology of culture proven typhoid fever.

    abstract::The authors analysed bone marrow findings of sixteen cases of culture proven typhoid fever to reveal the pathologic changes according to the disease stage. The most frequent finding was chronic granulomatous inflammation (eight cases). Infection (bacteria) associated hemophagocytic syndrome (four cases), reactive marr...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1994.9.1.57

    authors: Shin BM,Paik IK,Cho HI

    更新日期:1994-02-01 00:00:00

  • Collision of three histologically distinct endometrial cancers of the uterus.

    abstract::A collision tumor is defined by the presence of two separate masses in one organ, which are pathologically distinct. We described a 70-yr-old patient who complained of abnormal vaginal bleeding with a collision tumor of the uterine corpus. The patient received total hysterectomy, bilateral salphingo-oophorectomy, bila...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.2012.27.1.89

    authors: Jang KS,Lee WM,Kim YJ,Cho SH

    更新日期:2012-01-01 00:00:00

  • Transcatheter closure of fenestration with detachable coils after the Fontan operation.

    abstract::We report our experience in 13 patients who underwent transcatheter closure of Fontan fenestration with the Cook detachable coils. These patients underwent the extracardiac type Fontan operation with a short conduit fenestration (n=7) or lateral tunnel type with a punch-hole fenestration (n=6). Fenestration closure wa...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2006.21.5.859

    authors: Kim SH,Kang IS,Huh J,Lee HJ,Yang JH,Jun TG

    更新日期:2006-10-01 00:00:00

  • Comparison of Drug-Eluting Balloon Followed by Bare Metal Stent with Drug-Eluting Stent for Treatment of de Novo Lesions: Randomized, Controlled, Single-Center Clinical Trial.

    abstract::The combined use of a drug-eluting balloon (DEB) and a bare metal stent (BMS) for the treatment of de novo non-small vessel coronary artery diseases (CAD) remains to be evaluated. We investigated the efficacy of a sequential treatment using a DEB together with a BMS implantation in comparison to a zotarolimus-eluting ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,随机对照试验

    doi:10.3346/jkms.2017.32.6.933

    authors: Chae IH,Yoon CH,Park JJ,Oh IY,Suh JW,Cho YS,Youn TJ,Choi DJ

    更新日期:2017-06-01 00:00:00

  • Large subcutaneous calcification in systemic lupus erythematosus: treatment with oral aluminum hydroxide administration followed by surgical excision.

    abstract::A 32-year-old woman with a long-standing systemic lupus erythematosus had multiple subcutaneous nodules on her axillae, iliac crests and limbs. Three years ago, these nodules began to appear and slowly became larger. Some of them amassed to form a large, fungating, lobulated mass on her right iliac crest. Roentgenogra...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1999.14.5.589

    authors: Park YM,Lee SJ,Kang H,Cho SH

    更新日期:1999-10-01 00:00:00

  • The role of whole-body FDG PET/CT, Tc 99m MDP bone scintigraphy, and serum alkaline phosphatase in detecting bone metastasis in patients with newly diagnosed lung cancer.

    abstract::Bone scan (BS) and serum alkaline phosphatase (ALP) concentration are used to detect bone metastasis in malignancy, although whole-body fluoro-D-glucose positron emission tomography computed tomography (FDG PET/CT) is being used increasingly. But BS is still used for the detection of metastatic bone lesion. So we comp...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2009.24.2.275

    authors: Min JW,Um SW,Yim JJ,Yoo CG,Han SK,Shim YS,Kim YW

    更新日期:2009-04-01 00:00:00

  • Use of cytochrome c oxidase subunit i (COI) nucleotide sequences for identification of the Korean Luciliinae fly species (Diptera: Calliphoridae) in forensic investigations.

    abstract::Blowflies, especially species belonging to the subfamily Luciliinae, are the first insects to lay eggs on corpses in Korea. Fast and accurate species identification has been a key task for forensic entomologists. Because conventional morphologic identification methods have many limitations with respect to forensic pra...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2009.24.6.1058

    authors: Park SH,Zhang Y,Piao H,Yu DH,Jeong HJ,Yoo GY,Chung U,Jo TH,Hwang JJ

    更新日期:2009-12-01 00:00:00

  • Blood Pressure Curve for Children Less than 10 Years of Age: Findings from the Ewha Birth and Growth Cohort Study.

    abstract:BACKGROUND:Routine blood pressure (BP) measurement is recommended to begin at 3 years of age, but there are no national BP reference values for Korean children less than 7 years of age. Therefore, we developed sex-, age-, and height-specific BP reference values for non-overweight children aged 3-9 years. METHODS:We an...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2020.35.e91

    authors: Lee HA,Park B,Park EA,Cho SJ,Kim HS,Choi EJ,Kim NE,Park H

    更新日期:2020-03-30 00:00:00

  • Congenital insensitivity to pain with anhidrosis: a case report.

    abstract::Congenital insensitivity to pain with anhidrosis (CIPA) is a very rare genetic disorder of the peripheral nervous system characterized by recurrent episodes of unexplained fever, generalized anhidrosis, insensitivity to pain and temperature, and accompanied by self-mutilating behavior and mental retardation. We report...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1999.14.4.460

    authors: Kim JS,Woo YJ,Kim GM,Kim CJ,Ma JS,Hwang TJ,Lee MC

    更新日期:1999-08-01 00:00:00

  • The clinical measures associated with C-peptide decline in patients with type 1 diabetes over 15 years.

    abstract::This study was done to characterize the natural course of C-peptide levels in patients with type 1 diabetes and identify distinguishing characters among patients with lower rates of C-peptide decline. A sample of 95 children with type 1 diabetes was analyzed to retrospectively track serum levels of C-peptide, HbA1c, w...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2013.28.9.1340

    authors: Lee TH,Kwon AR,Kim YJ,Chae HW,Kim HS,Kim DH

    更新日期:2013-09-01 00:00:00

  • Anastomosis of vessels less than 2 mm with the vascular clip system clip applier.

    abstract::Sutures may cause endothelial trauma and occlusion. The vascular clip system (VCS) clip applier may minimize endothelial injury. Fourteen carotid arteries of nine adult rabbits were transected and re-anastomosed with either #7-0 polypropylene (Group I, n=8) or VCS clips (Group II, n=6). The animals were sacrificed at ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2001.16.3.303

    authors: Lee JW,Choo SJ,Oh JH,Lee I,Kwon YM,Lee YJ,Lee SK,Song H,Song MG

    更新日期:2001-06-01 00:00:00

  • Reactive cutaneous cytophagocytosis in nocardiosis.

    abstract::Cutaneous nocardiosis, which usually manifests in the form of pustules, abscesses, or subcutaneous nodules, is occasionally found in immunocompromised patients. A 59-yr-old Korean man with myasthenia gravis and thymoma developed nodular skin lesions on his trunk. Histopathologically, abscess formation with a dense inf...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2002.17.2.279

    authors: Kim CY,Kim TH,Lee WS,Lee AY

    更新日期:2002-04-01 00:00:00

  • Massive thrombosis after central venous catheterization in a patient with previously undiagnosed Behcet's disease.

    abstract::Thrombosis is an important complication of central venous catheterization. Among the many intrinsic and extrinsic factors, the patient's medical disease can play a role in thrombogenesis. Behcet's disease (BD), classified as a vasculitis, is a multisystem disease involving the small blood vessels. It is often difficul...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2001.16.6.814

    authors: Ko SH,Kang SK,Lee SK,Song HS

    更新日期:2001-12-01 00:00:00

  • Clinicopathologic analysis of 124 biopsy-proven peripheral nerve diseases.

    abstract::We reviewed dinical, histological and ultrastructural findings of 124 cases of sural nerve biopsy specimens to delineate the trends of peripheral nerve diseases in our institute. Eighty-one were men and 43 were women. We categorized them into five groups: specific diagnosis (66 cases, 53.2%), axonal degeneration type ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2000.15.2.211

    authors: Hong SM,Ha H,Suh JH,Kim KK,Khang SK,Ro JY,Park SH

    更新日期:2000-04-01 00:00:00