Abstract:
:Transverse myelitis (TM) extending from midbrain to the entire spinal cord accompanied by internuclear ophthalmoplegia is extremely rare but cause serious central nervous system complications in patients with systemic lupus erythematosus. We report a case of a 28-yr-old woman with TM extending from the midbrain to the conus medullaris longitudinally and internuclear ophthalmoplegia associated with systemic lupus erythematosus. Her neurological symptoms had an abrupt catastrophic onset and rapidly progressed to respiratory failure within 24 hr. Bilateral internuclear ophthalmoplegia was also followed by TM. Brain MR images showed definite brainstem lesions, which were deeply associated with internuclear ophthalmoplegia, and diffuse signal changes in the whole spinal cord, medulla, pons and midbrain. Clinical improvement of her ophthalmoplegia and of neurological dysfunction of the upper extremities was noted after prompt and aggressive treatment with intravenous pulsed methylprednisolone and cyclophosphamide. However, the neurological dysfunction of the lower limbs and bladder and colon paralysis were almost unchanged until six months passed.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Rheu CW,Lee SI,Yoo WHdoi
10.3346/jkms.2005.20.6.1085keywords:
subject
Has Abstractpub_date
2005-12-01 00:00:00pages
1085-8issue
6eissn
1011-8934issn
1598-6357pii
2005121085journal_volume
20pub_type
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journal_title:Journal of Korean medical science
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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journal_title:Journal of Korean medical science
pub_type: 杂志文章
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journal_title:Journal of Korean medical science
pub_type: 杂志文章
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journal_title:Journal of Korean medical science
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journal_title:Journal of Korean medical science
pub_type: 杂志文章
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更新日期:1999-08-01 00:00:00
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journal_title:Journal of Korean medical science
pub_type: 杂志文章
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更新日期:2010-11-01 00:00:00
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journal_title:Journal of Korean medical science
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更新日期:2017-10-01 00:00:00